Page last updated: 2024-11-06

alloxan and Extravascular Hemolysis

alloxan has been researched along with Extravascular Hemolysis in 9 studies

Alloxan: Acidic compound formed by oxidation of URIC ACID. It is isolated as an efflorescent crystalline hydrate.
alloxan : A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.

Research Excerpts

ExcerptRelevanceReference
"Three hours after iv administration of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine to mice infected with chloroquine-sensitive (CS) and chloroquine-resistant (CR) strains of Plasmodium berghei, the 2 compounds showed remarkable antimalarial actions."7.67[Antimalarial action of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine in Plasmodium berghei]. ( Chang, HL; Huang, ZY; Wang, JJ; Wu, KY, 1989)
"Alloxan, which was a drug that caused diabetes mellitus, mostly generated hydrogen peroxide by the reaction of alloxan and reduced glutathione, in vitro."3.75Low catalase activity in blood is associated with the diabetes caused by alloxan. ( Ishihara, K; Iwata, H; Masuoka, N; Nishihara, R; Ogino, K; Takemoto, K; Tanaka, M; Taniuchi, K; Wang, DH, 2009)
"Three hours after iv administration of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine to mice infected with chloroquine-sensitive (CS) and chloroquine-resistant (CR) strains of Plasmodium berghei, the 2 compounds showed remarkable antimalarial actions."3.67[Antimalarial action of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine in Plasmodium berghei]. ( Chang, HL; Huang, ZY; Wang, JJ; Wu, KY, 1989)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's1 (11.11)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Oršolić, N1
Sirovina, D1
Odeh, D1
Gajski, G1
Balta, V1
Šver, L1
Jazvinšćak Jembrek, M1
Ramkumar, KM1
Vijayakumar, RS1
Vanitha, P1
Suganya, N1
Manjula, C1
Rajaguru, P1
Sivasubramanian, S1
Gunasekaran, P1
LA BARRE, J1
HANQUINET, J1
Takemoto, K1
Tanaka, M1
Iwata, H1
Nishihara, R1
Ishihara, K1
Wang, DH1
Ogino, K1
Taniuchi, K1
Masuoka, N1
ROSE, CS1
GYORGY, P1
Clark, IA1
Hunt, NH1
Fee, JA2
Bergamini, R1
Briggs, RG1
Huang, ZY1
Chang, HL1
Wu, KY1
Wang, JJ1
Teitelbaum, HD1

Other Studies

9 other studies available for alloxan and Extravascular Hemolysis

ArticleYear
Efficacy of Caffeic Acid on Diabetes and Its Complications in the Mouse.
    Molecules (Basel, Switzerland), 2021, May-28, Volume: 26, Issue:11

    Topics: Alloxan; Animals; Antioxidants; Apoptosis; Atherosclerosis; Blood Glucose; Caffeic Acids; Diabetes C

2021
Protective effect of gallic acid on alloxan-induced oxidative stress and osmotic fragility in rats.
    Human & experimental toxicology, 2014, Volume: 33, Issue:6

    Topics: Alloxan; Animals; Antioxidants; Biomarkers; Blood Glucose; Catalase; Cytoprotection; Diabetes Mellit

2014
About changes in hepatic function during alloxanic diabetes.
    Archives internationales de pharmacodynamie et de therapie, 1948, Jul-01, Volume: 77, Issue:1

    Topics: Alloxan; Animals; Cell Death; Diabetes Mellitus, Experimental; Hemolysis

1948
Low catalase activity in blood is associated with the diabetes caused by alloxan.
    Clinica chimica acta; international journal of clinical chemistry, 2009, Volume: 407, Issue:1-2

    Topics: Acatalasia; Alloxan; Animals; Blood Glucose; Catalase; Diabetes Complications; Diabetes Mellitus; Gl

2009
Hemolysis with alloxan and alloxan-like compounds, and the protective action of tocopherol.
    Blood, 1950, Volume: 5, Issue:11

    Topics: Alloxan; Cell Death; Hemolysis; Tocopherols

1950
Evidence for reactive oxygen intermediates causing hemolysis and parasite death in malaria.
    Infection and immunity, 1983, Volume: 39, Issue:1

    Topics: Alloxan; Animals; Deferoxamine; Erythrocytes; Female; Free Radicals; Hemolysis; Hydrogen Peroxide; M

1983
Observations on the mechanism of the oxygen/dialuric acid-induced hemolysis of vitamin e-deficient rat red blood cells and the protective roles of catalase and superoxide dismutase.
    Archives of biochemistry and biophysics, 1975, Volume: 169, Issue:1

    Topics: Alloxan; Animals; Barbiturates; Catalase; Cell Membrane; Cytochrome c Group; Electron Spin Resonance

1975
[Antimalarial action of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine in Plasmodium berghei].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:2

    Topics: Alloxan; Animals; Antimalarials; Female; Glutathione Reductase; Hemolysis; Malaria; Mice; Plasmodium

1989
Evidence that superoxide dismutase plays a role in protecting red blood cells against peroxidative hemolysis.
    Biochemical and biophysical research communications, 1972, Oct-06, Volume: 49, Issue:1

    Topics: Aerobiosis; Alloxan; Animals; Barbiturates; Catalase; Drug Antagonism; Erythrocytes; Free Radicals;

1972