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alloxan and Edema, Pulmonary

alloxan has been researched along with Edema, Pulmonary in 43 studies

Alloxan: Acidic compound formed by oxidation of URIC ACID. It is isolated as an efflorescent crystalline hydrate.
alloxan : A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.

Research Excerpts

ExcerptRelevanceReference
"Induction of acute pulmonary edema with intravenously administered alloxan and administration of ANF according to five protocols."7.69Renal natriuretic effects of atrial natriuretic peptide in dogs with alloxan-induced acute pulmonary edema. ( Cernacek, P; Levy, M, 1996)
"To investigate how fast and to what extent superior vena caval hypertension (SVCH) increases lung water in acute increased-permeability state, we studied the time course of lung water accumulation for 3 h in anesthetized dogs under different treatments: 1) controls without intervention (5 dogs), 2) SVCH alone (5 dogs), 3) mild lung microvascular injury induced by low-dose alloxan (75 mg/kg) alone (5 dogs), and 4) SVCH coupled with low-dose alloxan (5 dogs)."7.68Effect of superior vena caval hypertension on alloxan-induced lung injury in dogs. ( Ando, F; Arakawa, M; Hirakawa, S; Kambara, K; Miyazaki, H; Segawa, T, 1990)
"We studied the incidence of electron microscopic pathological patterns of the alveolar septum observed 30 min after induction of pulmonary edema by dextran-70 infusion (6 dogs, dextran group) and by alloxan injection (6 dogs, alloxan group)."7.67Electron microscopic pathological patterns of alveolar septum in acute dextran-induced and alloxan-induced pulmonary edema in dogs. ( Arakawa, M; Hirakawa, S; Isono, H; Kambara, K; Nakahara, K; Oda, H; Shoumura, S, 1988)
"No radiologic evidence of pulmonary edema was demonstrated in two dogs studied in period 1."5.25"Closing volume" changes in alloxan-induced pulmonary edema in anesthetized dogs. ( Cowan, G; Graf, PD; Jones, JG; Lemen, R, 1975)
"Induction of acute pulmonary edema with intravenously administered alloxan and administration of ANF according to five protocols."3.69Renal natriuretic effects of atrial natriuretic peptide in dogs with alloxan-induced acute pulmonary edema. ( Cernacek, P; Levy, M, 1996)
" Pulmonary edema was induced in 18 mongrel dogs by either dextran (n = 12) or alloxan (n = 6) administration."3.68Ultrastructural substrates for increased lung water content in experimental pulmonary edema. ( Ando, F; Arakawa, M; Hirakawa, S; Isono, H; Kambara, K; Kawada, T; Nakahara, K; Oda, H; Segawa, T; Shoumura, S, 1993)
"To investigate how fast and to what extent superior vena caval hypertension (SVCH) increases lung water in acute increased-permeability state, we studied the time course of lung water accumulation for 3 h in anesthetized dogs under different treatments: 1) controls without intervention (5 dogs), 2) SVCH alone (5 dogs), 3) mild lung microvascular injury induced by low-dose alloxan (75 mg/kg) alone (5 dogs), and 4) SVCH coupled with low-dose alloxan (5 dogs)."3.68Effect of superior vena caval hypertension on alloxan-induced lung injury in dogs. ( Ando, F; Arakawa, M; Hirakawa, S; Kambara, K; Miyazaki, H; Segawa, T, 1990)
" The smoke-exposed animals were compared with controls and with animals exposed to alloxan or to high-pressure-induced pulmonary edema."3.68Distribution of extravascular lung water after acute smoke inhalation. ( Clark, WR; Hakim, TS; Nieman, G, 1990)
"To determine the effect of the type of lung injury on the thermodilution estimation of extravascular lung water, we produced pulmonary edema in 25 anesthetized dogs by injection of alloxan or alpha-naphthylthiourea (ANTU) into the pulmonary circulation or by instillation of hydrochloric acid (HCI) into the airway."3.67Type of lung injury influences the thermal-dye estimation of extravascular lung water. ( Carlile, PV; Gray, BA, 1984)
"We studied the incidence of electron microscopic pathological patterns of the alveolar septum observed 30 min after induction of pulmonary edema by dextran-70 infusion (6 dogs, dextran group) and by alloxan injection (6 dogs, alloxan group)."3.67Electron microscopic pathological patterns of alveolar septum in acute dextran-induced and alloxan-induced pulmonary edema in dogs. ( Arakawa, M; Hirakawa, S; Isono, H; Kambara, K; Nakahara, K; Oda, H; Shoumura, S, 1988)
" After inducing pulmonary edema using alloxan, functional residual capacity (FRC) decreased 38%, CL decreased 66% and RP increased 106% (p less than 0."3.67Effects of end-expiratory lung volume on lung mechanics in normal and edematous lungs. ( Carlstrom, JR; Richardson, P, 1985)
"Pulmonary edema caused by increased membrane permeability was created in dogs by alloxan and infusion of saline solution."3.66Effect of positive end-expiratory pressure on lung water in pulmonary edema caused by increased membrane permeability. ( Bredenberg, CE; Helbert, C; Paskanik, A, 1983)
" To test the hypothesis that [(14)C]urea might be used to distinguish pulmonary edema due to acutely increased intravascular pressure from that due to vascular damage by alloxan, we studied [(51)Cr]erythrocytes (r), [(125)I]albumin (a), [(14)C]urea (u), and tritiated water as dilution indicators in the pulmonary circulation of anesthetized dogs."3.65In vivo assessment of pulmonary vascular integrity in experimental pulmonary edema. ( Brigham, KL; Snell, JD, 1973)
"As overt pulmonary edema developed by dextran infusion, the ratio exponentially decreased to 1."1.27Fluid volume balance between pulmonary intravascular space and extravascular space in dogs. ( Arakawa, M; Hirakawa, S; Iinuma, J; Kambara, K; Miyazaki, H; Segawa, T; Yasuda, Y, 1986)
"Pulmonary edema has been proposed as a stimulus for pulmonary C-fibers."1.27Pulmonary edema in dogs fails to cause reflex responses. ( Cassidy, SS; Reynolds, RC; Wead, WB, 1987)
" Endotoxin treatment was associated with increased activity of the protectant antioxidant enzyme systems of the lung in an apparent dose-response manner."1.26Endotoxin protection against oxygen-induced acute and chronic lung injury. ( Frank, L; Roberts, RJ, 1979)
"During the pulmonary edema, 57Co-cyanocabalamin and 125I-albumin appeared in the blood and 131I-albumin entered the alveolar saline."1.26Solute permeability of the alveolar epithelium in alloxan edema in dogs. ( Egan, EA; McIntyre, BR; Nelson, RM, 1978)
"No radiologic evidence of pulmonary edema was demonstrated in two dogs studied in period 1."1.25"Closing volume" changes in alloxan-induced pulmonary edema in anesthetized dogs. ( Cowan, G; Graf, PD; Jones, JG; Lemen, R, 1975)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199036 (83.72)18.7374
1990's7 (16.28)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
AVIADO, DM1
SCHMIDT, CF1
ZAJIC, F2
FEJFAR, Z1
FEJFAROVA, M2
HLAVOVA, A1
PEARCE, ML3
YAMASHITA, J1
BEAZELL, J1
Staub, NC4
Nagano, H2
Cottrell, TS1
Levine, OR1
Senior, RM1
Wiener, J1
Spiro, D1
Fishman, AP1
Helbert, C1
Paskanik, A1
Bredenberg, CE1
Carlile, PV1
Gray, BA1
Adcock, DK1
Drake, RE2
Scott, RL1
Gabel, JC2
Uehara, C1
Romaldini, H1
Afonso, JE1
dos Santos, ML1
Ratto, OR1
Snashall, PD1
Keyes, SJ1
Morgan, BM1
McAnulty, RJ1
Mitchell-Heggs, PF1
Mclvor, JM1
Howlett, KA1
Derks, CM1
D'Hollander, AA1
Jacobovitz-Derks, D1
Prichard, JS1
Rajagopalan, B1
Lee, Gde J1
Awai, K1
Utsumi, T1
Kajima, T1
Fukuda, H1
Nakamura, S1
Fujikawa, K1
Azuma, K1
Ito, K1
Oda, H2
Arakawa, M5
Kambara, K5
Nakahara, K2
Segawa, T4
Ando, F3
Kawada, T2
Hirakawa, S5
Shoumura, S3
Isono, H3
Anand, A1
Paintal, AS2
Whitteridge, D1
Levy, M1
Cernacek, P1
Arens, JF1
Taylor, AE1
Hopewell, PC1
Frank, L1
Roberts, RJ1
Vreim, CE1
Ohkuda, K1
Nelson, RM1
McIntyre, BR1
Egan, EA1
Coleridge, JC1
Coleridge, HM1
Lemen, R2
Jones, JG2
Graf, PD2
Cowan, G1
Neufeld, GR1
Williams, JJ1
Graves, DJ1
Soma, LR1
Marshall, BE1
Emura, S1
Miyazaki, H2
Clark, WR1
Nieman, G1
Hakim, TS1
Iinuma, J1
Yasuda, Y1
Wead, WB1
Cassidy, SS1
Reynolds, RC1
Richardson, P1
Carlstrom, JR1
Brigham, KL1
Snell, JD1
Hyman, AL1
Pennington, DG1
Kadowitz, PJ1
Meyer, EC2
Ottaviano, R2
Baker, LE1
Denniston, JC1
Ritchie, BC1
Schauberger, G1
Szám, I1
Nikolits, I1
Dési, I1
Gottsegen, G2
Kellner, M1
Kovách, AG1
Maklári, E1

Other Studies

43 other studies available for alloxan and Edema, Pulmonary

ArticleYear
Pathogenesis of pulmonary edema by alloxan.
    Circulation research, 1957, Volume: 5, Issue:2

    Topics: Alloxan; Pulmonary Edema

1957
[Experimental alloxan pulmonary edema. II. Respiratory changes].
    Ceskoslovenska fysiologie, 1959, Volume: 8, Issue:3

    Topics: Alloxan; Pulmonary Edema

1959
Experimental pulmonary oedema produced by alloxan. II. Haemodynamic and respiratory changes in vagotomised dogs.
    Cor et vasa, 1962, Volume: 4

    Topics: Alloxan; Animals; Blood Coagulation; Blood Physiological Phenomena; Cell Respiration; Dogs; Hemodyna

1962
MEASUREMENT OF PULMONARY EDEMA.
    Circulation research, 1965, Volume: 16

    Topics: Alloxan; Animals; Blood Gas Analysis; Body Fluids; Carbon Dioxide; Dogs; Hydrogen-Ion Concentration;

1965
Pulmonary edema in dogs, especially the sequence of fluid accumulation in lungs.
    Journal of applied physiology, 1967, Volume: 22, Issue:2

    Topics: Alloxan; Animals; Blood Flow Velocity; Blood Pressure; Blood Transfusion; Blood Volume; Capillaries;

1967
Electron microscopic alterations at the alveolar level in pulmonary edema.
    Circulation research, 1967, Volume: 21, Issue:6

    Topics: Alloxan; Animals; Carbon; Dogs; Hemodynamics; Microscopy, Electron; Pulmonary Alveoli; Pulmonary Ede

1967
Effect of positive end-expiratory pressure on lung water in pulmonary edema caused by increased membrane permeability.
    The Annals of thoracic surgery, 1983, Volume: 36, Issue:1

    Topics: Alloxan; Animals; Body Water; Capillary Permeability; Cardiac Output; Dogs; Hydrostatic Pressure; Po

1983
Type of lung injury influences the thermal-dye estimation of extravascular lung water.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1984, Volume: 57, Issue:3

    Topics: Alloxan; Animals; Cardiac Output; Dogs; Extracellular Space; Hydrochloric Acid; Lung; Pulmonary Circ

1984
Dog lymph flow in increased capillary permeability states.
    Microvascular research, 1983, Volume: 25, Issue:3

    Topics: Alloxan; Animals; Blood Pressure; Capillary Permeability; Dogs; Lung; Lymph; Pulmonary Edema

1983
[Physiopathology of pulmonary edema due to the increase of microvascular permeability. Experimental study in dogs].
    Arquivos brasileiros de cardiologia, 1982, Volume: 39, Issue:6

    Topics: Alloxan; Animals; Blood Pressure; Capillary Permeability; Dogs; Pulmonary Edema

1982
The radiographic detection of acute pulmonary oedema. A comparison of radiographic appearances, densitometry and lung water in dogs.
    The British journal of radiology, 1981, Volume: 54, Issue:640

    Topics: Absorptiometry, Photon; Acute Disease; Alloxan; Animals; Body Water; Dogs; Female; Lung; Male; Pulmo

1981
Gas exchange and respiratory mechanics in moderate and severe pulmonary oedema in dogs.
    Bulletin europeen de physiopathologie respiratoire, 1981, Volume: 17, Issue:2

    Topics: Alloxan; Animals; Disease Models, Animal; Dogs; Lung; Lung Volume Measurements; Oleic Acids; Pulmona

1981
Transvascular albumin flux and the interstitial water volume in experimental pulmonary oedema in dogs.
    Clinical science (London, England : 1979), 1980, Volume: 59, Issue:2

    Topics: Alloxan; Animals; Blood Pressure; Blood Proteins; Capillary Permeability; Dogs; Half-Life; Hypotensi

1980
[Experimental study on early detection of alloxan-induced pulmonary injury by magnetic resonance imaging].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1995, Volume: 55, Issue:9

    Topics: Alloxan; Animals; Female; Lung; Magnetic Resonance Imaging; Pulmonary Edema; Rats; Rats, Wistar; Tom

1995
Ultrastructural substrates for increased lung water content in experimental pulmonary edema.
    Histology and histopathology, 1993, Volume: 8, Issue:1

    Topics: Alloxan; Animals; Dextrans; Dogs; Extravascular Lung Water; Female; Lung; Male; Microscopy, Electron

1993
Mechanisms underlying enhanced responses of J receptors of cats to excitants in pulmonary oedema.
    The Journal of physiology, 1993, Volume: 471

    Topics: Alloxan; Animals; Biguanides; Bradykinin; Capillary Permeability; Capsaicin; Cats; Histamine; Lung C

1993
Renal natriuretic effects of atrial natriuretic peptide in dogs with alloxan-induced acute pulmonary edema.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1996, Volume: 19, Issue:6

    Topics: Acute Disease; Alloxan; Animals; Atrial Natriuretic Factor; Catalase; Diuresis; Dogs; Female; Glomer

1996
Unchanged pulmonary capillary filtration coefficients after Escherichia coli endotoxin infusion.
    The Journal of surgical research, 1978, Volume: 25, Issue:2

    Topics: Alloxan; Animals; Blood Pressure; Blood Volume; Capillary Permeability; Cardiac Output; Dogs; Endoto

1978
Failure of positive end-expiratory pressure to decrease lung water content in alloxan-induced pulmonary edema.
    The American review of respiratory disease, 1979, Volume: 120, Issue:4

    Topics: Alloxan; Animals; Body Water; Disease Models, Animal; Dogs; Lung; Oxygen; Positive-Pressure Respirat

1979
Endotoxin protection against oxygen-induced acute and chronic lung injury.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1979, Volume: 47, Issue:3

    Topics: Alloxan; Animals; Dose-Response Relationship, Drug; Endotoxins; Hemorrhage; Lung Diseases; Oleic Aci

1979
Proportions of dog lung lymph in the thoracic and right lymph ducts.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1977, Volume: 43, Issue:5

    Topics: Alloxan; Animals; Blood Proteins; Dogs; Female; Lung; Lymph; Lymphatic System; Male; Pulmonary Edema

1977
Solute permeability of the alveolar epithelium in alloxan edema in dogs.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1978, Volume: 44, Issue:3

    Topics: Alloxan; Animals; Cell Membrane; Cell Membrane Permeability; Dogs; Pulmonary Alveoli; Pulmonary Edem

1978
Afferent C-fibers and cardiorespiratory chemoreflexes.
    The American review of respiratory disease, 1977, Volume: 115, Issue:6 Pt 2

    Topics: Alloxan; Animals; Capsaicin; Cats; Dogs; Heart; Lung; Nerve Fibers; Pressure; Prostaglandins; Pulmon

1977
"Closing volume" changes in alloxan-induced pulmonary edema in anesthetized dogs.
    Journal of applied physiology, 1975, Volume: 39, Issue:2

    Topics: Alloxan; Animals; Blood Pressure; Dogs; Femoral Artery; Lung; Lung Volume Measurements; Oxygen; Pulm

1975
Pulmonary capillary permeability in man and a canine model of chemical pulmonary edema.
    Microvascular research, 1975, Volume: 10, Issue:2

    Topics: Adult; Alloxan; Animals; Blood Flow Velocity; Blood Pressure; Blood Volume; Capillaries; Capillary P

1975
Pretreatment with catalase or dimethyl sulfoxide protects alloxan-induced acute lung edema in dogs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Alloxan; Animals; Blood Pressure; Catalase; Dimethyl Su

1992
Effect of superior vena caval hypertension on alloxan-induced lung injury in dogs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 68, Issue:2

    Topics: Alloxan; Animals; Dogs; Extravascular Lung Water; Hypertension; Lung; Lung Injury; Pulmonary Edema;

1990
Distribution of extravascular lung water after acute smoke inhalation.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 68, Issue:6

    Topics: Alloxan; Animals; Blood Pressure; Blood Vessels; Body Water; Capillary Permeability; Dogs; Lung; Lun

1990
Fluid volume balance between pulmonary intravascular space and extravascular space in dogs.
    Japanese circulation journal, 1986, Volume: 50, Issue:9

    Topics: Alloxan; Animals; Blood Volume; Body Water; Dextrans; Dogs; Dye Dilution Technique; Extracellular Sp

1986
Electron microscopic pathological patterns of alveolar septum in acute dextran-induced and alloxan-induced pulmonary edema in dogs.
    Histology and histopathology, 1988, Volume: 3, Issue:4

    Topics: Alloxan; Animals; Dextrans; Dogs; Microscopy, Electron; Pulmonary Alveoli; Pulmonary Edema

1988
Pulmonary edema in dogs fails to cause reflex responses.
    The American journal of physiology, 1987, Volume: 252, Issue:1 Pt 2

    Topics: Alloxan; Animals; Blood Pressure; Capsaicin; Dogs; Female; Heart Rate; Lung; Male; Pulmonary Edema;

1987
Effects of end-expiratory lung volume on lung mechanics in normal and edematous lungs.
    Respiration; international review of thoracic diseases, 1985, Volume: 47, Issue:2

    Topics: Alloxan; Animals; Body Weight; Cats; Lung; Lung Compliance; Lung Volume Measurements; Nitrogen; Posi

1985
Proceedings: "Airway closure" in alloxan induced pulmonary oedema and raised left atrial pressure.
    British journal of anaesthesia, 1974, Volume: 46, Issue:4

    Topics: Airway Resistance; Alloxan; Animals; Blood Pressure; Cardiac Catheterization; Dogs; Pulmonary Edema;

1974
In vivo assessment of pulmonary vascular integrity in experimental pulmonary edema.
    The Journal of clinical investigation, 1973, Volume: 52, Issue:8

    Topics: Alloxan; Animals; Blood; Blood Pressure; Blood Vessels; Carbon Dioxide; Carbon Isotopes; Cell Membra

1973
Effect of acute pulmonary edema on pulmonary arterial pressure in intact dogs.
    The American journal of physiology, 1973, Volume: 224, Issue:1

    Topics: Acute Disease; Alloxan; Animals; Blood Flow Velocity; Blood Pressure; Catheterization; Dogs; Female;

1973
The effect of fibrin on the morphometric distribution of pulmonary exudative edema.
    Laboratory investigation; a journal of technical methods and pathology, 1973, Volume: 29, Issue:3

    Topics: Alloxan; Animals; Autoradiography; Blood Pressure; Body Weight; Bronchi; Dogs; Exudates and Transuda

1973
Noninvasive measurement of intrathoracic fluids.
    Chest, 1974, Volume: 65

    Topics: Alloxan; Animals; Body Fluids; Dogs; Electrodes; Methods; Plethysmography, Impedance; Pulmonary Edem

1974
Pulmonary collateral lymph flow: detection using lymph oxygen tensions.
    Journal of applied physiology, 1972, Volume: 32, Issue:6

    Topics: Alloxan; Animals; Blood Pressure; Body Water; Dogs; Femoral Artery; Intestines; Liver; Lung; Lymph;

1972
The sequence of events during fluid accumulation in acute pulmonary edema.
    Japanese heart journal, 1967, Volume: 8, Issue:6

    Topics: Acute Disease; Alloxan; Animals; Dogs; Exudates and Transudates; Lung; Pulmonary Alveoli; Pulmonary

1967
Mechanism of stimulation of type J pulmonary receptors.
    The Journal of physiology, 1969, Volume: 203, Issue:3

    Topics: Action Potentials; Alloxan; Animals; Blood Pressure; Capillaries; Cats; Chlorine; Halothane; Histami

1969
Inadequacy of perivascular edema hypothesis to account for distribution of pulmonary blood flow in lung edema.
    Circulation research, 1969, Volume: 24, Issue:6

    Topics: Alloxan; Animals; Blood Pressure; Dogs; Pressure; Pulmonary Alveoli; Pulmonary Circulation; Pulmonar

1969
Electroencephalographic studies in experimental pulmonary oedema.
    Acta medica Academiae Scientiarum Hungaricae, 1965, Volume: 21, Issue:2

    Topics: Alloxan; Ammonium Chloride; Animals; Brain; Cats; Electroencephalography; Epinephrine; Female; Male;

1965
Studies on the pathogenesis of pulmonary alloxan oedema.
    Acta medica Academiae Scientiarum Hungaricae, 1965, Volume: 21, Issue:2

    Topics: Alloxan; Animals; Blood Pressure; Cerebrovascular Circulation; Dogs; Parabiosis; Pulmonary Edema

1965