Page last updated: 2024-11-06

alloxan and Diabetic Retinopathy

alloxan has been researched along with Diabetic Retinopathy in 20 studies

Alloxan: Acidic compound formed by oxidation of URIC ACID. It is isolated as an efflorescent crystalline hydrate.
alloxan : A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.

Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

Research Excerpts

ExcerptRelevanceReference
"Hyperglycemia is the primary cause of the majority of diabetes complications, including diabetic retinopathy (DR)."1.40Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy. ( Gurel, Z; Pratt, MR; Sheibani, N; Zaro, BW, 2014)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19908 (40.00)18.7374
1990's5 (25.00)18.2507
2000's4 (20.00)29.6817
2010's2 (10.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Shi, J1
Li, L1
Gurel, Z1
Zaro, BW1
Pratt, MR1
Sheibani, N1
King, JL1
Mason, JO1
Cartner, SC1
Guidry, C1
DE ROETTH, A1
YEN, FP1
DEROETTH, A1
PEI, YF1
SCHRADER, KE1
Gaucher, D1
Chiappore, JA1
Pâques, M1
Simonutti, M1
Boitard, C1
Sahel, JA1
Massin, P1
Picaud, S1
Liu, SQ1
Kang, J1
Li, CJ1
Tang, EJ1
Wen, B1
Cai, R1
Yang, HJ1
Kern, TS2
Engerman, RL1
Mizutani, M1
Lorenzi, M1
Zarebska, A2
Łańcut, M1
Bakiera, K2
Matejko, E1
Czerny, K2
Kiś, G2
Wójtowicz, Z2
Cichacz-Kwiatkowska, B1
Lis-Sochocka, M1
Matas, AJ1
Sutherland, DE1
Steffes, MW1
Najarian, JS1
Okamoto, T1
Oikawa, S1
Toyota, T1
Schröder, S1
Palinski, W1
Schmid-Schönbein, GW1
Ben-Nun, J1
Alder, VA1
Constable, IJ1
Roberts, CE1
Wang, M1
Wang, YH1
Srivastava, Y1
Venkatakrishna-Bhatt, H1
Verma, Y1
Prem, AS1
Yuchi, Y1
Sakumichi, K1
Murata, H1

Reviews

1 review available for alloxan and Diabetic Retinopathy

ArticleYear
Islet transplantation.
    Surgery, gynecology & obstetrics, 1977, Volume: 145, Issue:5

    Topics: Alloxan; Animals; Blood Glucose; Body Weight; Carbohydrate Metabolism; Diabetes Mellitus; Diabetes M

1977

Other Studies

19 other studies available for alloxan and Diabetic Retinopathy

ArticleYear
circKMT2E Protect Retina from Early Diabetic Retinopathy through SIRT1 Signaling Pathway via Sponging miR-204-5p.
    Computational and mathematical methods in medicine, 2022, Volume: 2022

    Topics: Alloxan; Diabetes Mellitus; Diabetic Retinopathy; Humans; MicroRNAs; Retina; RNA, Circular; Signal T

2022
Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Acetylglucosamine; Alloxan; Animals; Apoptosis; Diabetic Retinopathy; Disease Models, Animal; Endoth

2014
The influence of alloxan-induced diabetes on Müller cell contraction-promoting activities in vitreous.
    Investigative ophthalmology & visual science, 2011, Sep-27, Volume: 52, Issue:10

    Topics: Alloxan; Animals; Blood Glucose; Blotting, Western; Carbonic Anhydrase I; Carbonic Anhydrase II; Dia

2011
Experimental diabetic retinopathy. Retinal metabolism in the alloxan diabetic rat.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1960, Volume: 63

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Rats; Retina

1960
METABOLISM OF THE ALLOXAN DIABETIC RAT RETINA.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1964, Volume: 71

    Topics: Adrenalectomy; Alloxan; Animals; Chlorpropamide; Diabetes Mellitus, Experimental; Diabetic Retinopat

1964
[BLOOD SUGAR CURVES AND LENS OPACITIES AFTER ALLOXAN APPLICATION IN RATS].
    Bericht uber die Zusammenkunft. Deutsche Ophthalmologische Gesellschaft, 1964, Volume: 65

    Topics: Alloxan; Animals; Blood Glucose; Cataract; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Ra

1964
Microglial changes occur without neural cell death in diabetic retinopathy.
    Vision research, 2007, Volume: 47, Issue:5

    Topics: Alloxan; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electroretinogra

2007
Differences in expression of retinal proteins between diabetic and normal rats.
    World journal of gastroenterology, 2007, Apr-14, Volume: 13, Issue:14

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Ele

2007
Comparison of retinal lesions in alloxan-diabetic rats and galactose-fed rats.
    Current eye research, 1994, Volume: 13, Issue:12

    Topics: Alloxan; Animals; Basement Membrane; Capillaries; Diabetes Mellitus, Experimental; Diabetic Retinopa

1994
Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy.
    The Journal of clinical investigation, 1996, Jun-15, Volume: 97, Issue:12

    Topics: Aged; Alloxan; Animals; Cell Death; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Female; H

1996
Ultrastructural changes in the receptor parts of retinal rods in experimental alloxan-induced diabetes in rabbits.
    Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 2001, Volume: 56

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Progression; Male;

2001
Histological changes in the retina in experimental alloxan-induced diabetes in rabbits.
    Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 2001, Volume: 56

    Topics: Alloxan; Animals; Cell Nucleus; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Progr

2001
Absence of angiogenesis-inhibitory activity in aqueous humor of diabetic rabbits.
    Diabetes, 1990, Volume: 39, Issue:1

    Topics: Allantois; Alloxan; Animals; Aqueous Humor; Cattle; Cell Division; Cells, Cultured; Chorion; Diabete

1990
Activated monocytes and granulocytes, capillary nonperfusion, and neovascularization in diabetic retinopathy.
    The American journal of pathology, 1991, Volume: 139, Issue:1

    Topics: Alloxan; Animals; Capillaries; Diabetic Retinopathy; Granulocytes; Hyperglycemia; Leukocytes; Macrop

1991
The patency of the retinal vasculature to erythrocytes in retinal vascular disease.
    Investigative ophthalmology & visual science, 1990, Mar-01, Volume: 31, Issue:3

    Topics: Alloxan; Animals; Diabetic Retinopathy; Disease Models, Animal; Endothelium, Vascular; Erythrocytes;

1990
[A morphological study of the retinal vessels in experimental diabetic rats].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 1989, Volume: 25, Issue:1

    Topics: Alloxan; Animals; Capillaries; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Male; Rats; Ra

1989
Retardation of retinopathy by Momordica charantia L. (bitter gourd) fruit extract in alloxan diabetic rats.
    Indian journal of experimental biology, 1987, Volume: 25, Issue:8

    Topics: Administration, Oral; Alloxan; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; N-Gly

1987
[Experimental study on the production of diabetic retinopathy. Preliminary report].
    Nihon ganka kiyo, 1971, Volume: 22, Issue:9

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Diet; Disease Models, Anima

1971
[The retinal metabolism of experimental diabetic rabbits. II. The influence of alloxan injection on the retinal metabolism].
    Nippon Ganka Gakkai zasshi, 1964, Volume: 68, Issue:7

    Topics: Alloxan; Animals; Diabetic Retinopathy; Rabbits; Retina

1964