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alloxan and Atherogenesis

alloxan has been researched along with Atherogenesis in 10 studies

Alloxan: Acidic compound formed by oxidation of URIC ACID. It is isolated as an efflorescent crystalline hydrate.
alloxan : A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.

Research Excerpts

ExcerptRelevanceReference
" We histologically assessed the atherosclerotic lesion development, cellular content, pimonidazole positive-hypoxic area, the nuclear localization of hypoxia-inducible factor-1α, and apoptosis."7.85Altered glucose metabolism and hypoxic response in alloxan-induced diabetic atherosclerosis in rabbits. ( Asada, Y; Iwakiri, T; Kawai, K; Kitamura, K; Koshimoto, C; Kuge, Y; Matsuura, Y; Sugita, C; Tamaki, N; Yamasaki, K; Yamashita, A; Zhao, S; Zhao, Y, 2017)
"Experiments were undertaken to ascertain whether the previously demonstrated inhibition of the development of experimental aortic atherosclerosis in alloxan-diabetic rabbits fed cholesterol was due to the injection of alloxan per se or to the existence of the diabetic state produced by alloxan."7.63The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit. IV. The effect of insulin therapy on the inhibition of atherosclerosis in the alloxan-diabetic rabbit. ( BRECHIN, DJ; DUFF, GL; FINKELSTEIN, WE, 1954)
" We histologically assessed the atherosclerotic lesion development, cellular content, pimonidazole positive-hypoxic area, the nuclear localization of hypoxia-inducible factor-1α, and apoptosis."3.85Altered glucose metabolism and hypoxic response in alloxan-induced diabetic atherosclerosis in rabbits. ( Asada, Y; Iwakiri, T; Kawai, K; Kitamura, K; Koshimoto, C; Kuge, Y; Matsuura, Y; Sugita, C; Tamaki, N; Yamasaki, K; Yamashita, A; Zhao, S; Zhao, Y, 2017)
"Experiments were undertaken to ascertain whether the previously demonstrated inhibition of the development of experimental aortic atherosclerosis in alloxan-diabetic rabbits fed cholesterol was due to the injection of alloxan per se or to the existence of the diabetic state produced by alloxan."3.63The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit. IV. The effect of insulin therapy on the inhibition of atherosclerosis in the alloxan-diabetic rabbit. ( BRECHIN, DJ; DUFF, GL; FINKELSTEIN, WE, 1954)
"Alloxan was used to induce diabetes in male Watanabe heritable hyperlipidemic (WHHL) rabbits that were sacrificed 2 and 6 months after the induction of diabetes."1.33VEGF-A, VEGF-D, VEGF receptor-1, VEGF receptor-2, NF-kappaB, and RAGE in atherosclerotic lesions of diabetic Watanabe heritable hyperlipidemic rabbits. ( Ahtialansaari, T; Babu, M; Bhardwaj, S; Hakumaki, J; Herzig, KH; Kokina, I; Laakso, M; Laitinen, T; Roy, H; Uotila, S; Ylä-Herttuala, S, 2006)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's1 (10.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Elseweidy, MM1
Elnagar, GM1
M Elsawy, M1
Ali, AA1
Zein, N1
Oršolić, N1
Sirovina, D1
Odeh, D1
Gajski, G1
Balta, V1
Šver, L1
Jazvinšćak Jembrek, M1
Matsuura, Y1
Yamashita, A1
Zhao, Y1
Iwakiri, T1
Yamasaki, K1
Sugita, C1
Koshimoto, C1
Kitamura, K1
Kawai, K1
Tamaki, N1
Zhao, S1
Kuge, Y1
Asada, Y1
DUFF, GL3
McMILLAN, GC1
Gupta, S1
Sharma, SB1
Prabhu, KM1
COOK, DL1
MILLS, LM1
GREEN, DM1
BRECHIN, DJ1
FINKELSTEIN, WE1
PAYNE, TP1
Dhar, P1
Bhattacharyya, D1
Bhattacharyya, DK1
Ghosh, S1
Roy, H1
Bhardwaj, S1
Babu, M1
Kokina, I1
Uotila, S1
Ahtialansaari, T1
Laitinen, T1
Hakumaki, J1
Laakso, M1
Herzig, KH1
Ylä-Herttuala, S1

Other Studies

10 other studies available for alloxan and Atherogenesis

ArticleYear
Losartan and azelastine either alone or in combination as modulators for endothelial dysfunction and platelets activation in diabetic hyperlipidemic rats.
    The Journal of pharmacy and pharmacology, 2020, Volume: 72, Issue:12

    Topics: Alloxan; Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Blood Platelets; Diabete

2020
Efficacy of Caffeic Acid on Diabetes and Its Complications in the Mouse.
    Molecules (Basel, Switzerland), 2021, May-28, Volume: 26, Issue:11

    Topics: Alloxan; Animals; Antioxidants; Apoptosis; Atherosclerosis; Blood Glucose; Caffeic Acids; Diabetes C

2021
Altered glucose metabolism and hypoxic response in alloxan-induced diabetic atherosclerosis in rabbits.
    PloS one, 2017, Volume: 12, Issue:4

    Topics: Alloxan; Animals; Apoptosis; Atherosclerosis; Autoradiography; Body Weight; Cluster Analysis; Diabet

2017
The inhibition of experimental cholesterol atherosclerosis by alloxan diabetes in the rabbit.
    American heart journal, 1948, Volume: 36, Issue:3

    Topics: Alloxan; Animals; Atherosclerosis; Cholesterol; Diabetes Mellitus, Experimental; Humans; Rabbits

1948
Ameliorative effect of Cassia auriculata L. leaf extract on glycemic control and atherogenic lipid status in alloxan-induced diabetic rabbits.
    Indian journal of experimental biology, 2009, Volume: 47, Issue:12

    Topics: Alloxan; Animals; Atherosclerosis; Blood Glucose; Cassia; Cholesterol, HDL; Cholesterol, LDL; Diabet

2009
The mechanism of alloxan protection in experimental atherosclerosis.
    The Journal of experimental medicine, 1954, Volume: 99, Issue:2

    Topics: Alloxan; Animals; Arteriosclerosis; Atherosclerosis; Cholesterol; Diabetes Mellitus, Experimental; L

1954
The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit. IV. The effect of insulin therapy on the inhibition of atherosclerosis in the alloxan-diabetic rabbit.
    The Journal of experimental medicine, 1954, Oct-01, Volume: 100, Issue:4

    Topics: Alloxan; Animals; Arteriosclerosis; Atherosclerosis; Blood Glucose; Cholesterol; Diabetes Mellitus,

1954
The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit. III. The mechanism of the inhibition of experimental cholesterol atherosclerosis in alloxan-diabetic rabbits.
    The Journal of experimental medicine, 1950, Oct-01, Volume: 92, Issue:4

    Topics: Alloxan; Animals; Aorta; Arteriosclerosis; Atherosclerosis; Blood Glucose; Cholesterol; Diabetes Mel

1950
Dietary comparison of conjugated linolenic acid (9 cis, 11 trans, 13 trans) and alpha-tocopherol effects on blood lipids and lipid peroxidation in alloxan-induced diabetes mellitus in rats.
    Lipids, 2006, Volume: 41, Issue:1

    Topics: Alloxan; alpha-Tocopherol; Animals; Atherosclerosis; Diabetes Mellitus, Experimental; Diet; Erythroc

2006
VEGF-A, VEGF-D, VEGF receptor-1, VEGF receptor-2, NF-kappaB, and RAGE in atherosclerotic lesions of diabetic Watanabe heritable hyperlipidemic rabbits.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:12

    Topics: Alloxan; Animals; Atherosclerosis; Diabetes Mellitus, Experimental; Disease Models, Animal; Hyperlip

2006