alloxan and Aging
alloxan has been researched along with Aging in 18 studies
Alloxan: Acidic compound formed by oxidation of URIC ACID. It is isolated as an efflorescent crystalline hydrate.
alloxan : A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the histological alterations of extracellular matrix in long-term alloxan-induced diabetes and aging urethras of male rats with descriptions of total connective tissue, muscle layer and collagen types I and III relative amounts." | 7.77 | Histologic study of urethral extracellular matrix and collagen from aging and long-term alloxan-induced diabetic male rats. ( Cassini, MF; Cologna, AJ; Fazan, VP; Foss, MC; Martins, AC; Reis, RB; Rodrigues, AA; Suaid, HJ; Tucci, S, 2011) |
| "to evaluate structural and functional effects of Alloxan- induced diabetes and aging on bladder of rats." | 7.74 | Long term evaluation of functional and morphological bladder alterations on alloxan-induced diabetes and aging: experimental study in rats. ( Cologna, AJ; Fazan, VP; Foss, MC; Martins, AC; Rodrigues, AA; Suaid, HJ; Tucci, S, 2008) |
| "Thus, alloxan diabetes increases ADA activity in an age- and tissue-specific manner." | 5.30 | Alloxan diabetes regulates adenosine deaminase activity in mice: tissue- and age-specific correlation. ( Sharma, R; Singh, LS, 1998) |
| "To evaluate the histological alterations of extracellular matrix in long-term alloxan-induced diabetes and aging urethras of male rats with descriptions of total connective tissue, muscle layer and collagen types I and III relative amounts." | 3.77 | Histologic study of urethral extracellular matrix and collagen from aging and long-term alloxan-induced diabetic male rats. ( Cassini, MF; Cologna, AJ; Fazan, VP; Foss, MC; Martins, AC; Reis, RB; Rodrigues, AA; Suaid, HJ; Tucci, S, 2011) |
| "to evaluate structural and functional effects of Alloxan- induced diabetes and aging on bladder of rats." | 3.74 | Long term evaluation of functional and morphological bladder alterations on alloxan-induced diabetes and aging: experimental study in rats. ( Cologna, AJ; Fazan, VP; Foss, MC; Martins, AC; Rodrigues, AA; Suaid, HJ; Tucci, S, 2008) |
| "Alloxan-induced hyperglycemia was accompanied by activation of lipid peroxidation processes with different degree of their completeness depending on the age of experimental animals." | 3.73 | Age-related differences in the degree of lipid peroxidation and state of antioxidant protection under the influence of alloxan. ( Gvozdenko, TA; Yan'kova, VI, 2005) |
| "Alloxan diabetes in lizards Calotes versicolor, belonging to three age groups, induced decreased levels of percentage of solubility of collagen in dorsal and ventral skin regions after 7 days of treatment." | 3.67 | Alloxan-induced changes in the collagen characteristics in the skin of male garden lizards, Calotes versicolor, from three age groups. ( Behera, HN; Mishra, G, 1986) |
| "Alloxan treatment reduced HSP90 levels and promoted proteasomal degradation of tau, c-Jun N-amino terminal kinase, and histone deacetylase (HDAC) 6." | 1.38 | Adaptive responses to alloxan-induced mild oxidative stress ameliorate certain tauopathy phenotypes. ( Kimura, T; Maeda, S; Mizoroki, T; Murayama, M; Sahara, N; Soeda, Y; Takashima, A; Yamashita, S; Yoshiike, Y, 2012) |
| "Thus, alloxan diabetes increases ADA activity in an age- and tissue-specific manner." | 1.30 | Alloxan diabetes regulates adenosine deaminase activity in mice: tissue- and age-specific correlation. ( Sharma, R; Singh, LS, 1998) |
| "Both methylene blue and CoCl2 have been found to accelerate the ageing of collagen in normal lizards." | 1.28 | Effect of methylene blue and cobaltous chloride on the alloxan-induced changes in collagen characteristics in the skin of garden lizard Calotes versicolor. ( Behera, HN; Mishra, G, 1989) |
Research
Studies (18)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (61.11) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Kara, A | 1 |
| Unal, D | 1 |
| Simsek, N | 1 |
| Yucel, A | 1 |
| Yucel, N | 1 |
| Selli, J | 1 |
| Rodrigues, AA | 2 |
| Suaid, HJ | 2 |
| Tucci, S | 2 |
| Fazan, VP | 2 |
| Foss, MC | 2 |
| Cologna, AJ | 2 |
| Martins, AC | 2 |
| Reis, RB | 1 |
| Cassini, MF | 1 |
| Yoshiike, Y | 1 |
| Yamashita, S | 1 |
| Mizoroki, T | 1 |
| Maeda, S | 1 |
| Murayama, M | 1 |
| Kimura, T | 1 |
| Sahara, N | 1 |
| Soeda, Y | 1 |
| Takashima, A | 1 |
| MULLER, HK | 1 |
| KLEIFELD, O | 1 |
| FUCHS, R | 1 |
| DARDENNE, U | 1 |
| HOCKWIN, O | 1 |
| ARENS, P | 1 |
| SOKOLOVEROVA, IM | 1 |
| Yan'kova, VI | 1 |
| Gvozdenko, TA | 1 |
| Riley, WJ | 1 |
| McConnell, TJ | 1 |
| Maclaren, NK | 1 |
| McLaughlin, JV | 1 |
| Taylor, G | 1 |
| Altura, BM | 1 |
| Lum, G | 1 |
| Turlapaty, PD | 1 |
| Altura, BT | 1 |
| Kodama, T | 1 |
| Iwase, M | 1 |
| Nunoi, K | 1 |
| Maki, Y | 1 |
| Yoshinari, M | 1 |
| Fujishima, M | 1 |
| Singh, LS | 1 |
| Sharma, R | 1 |
| Mishra, G | 2 |
| Behera, HN | 2 |
| Broekhuyse, RM | 1 |
| Rowsell, EV | 1 |
| al-Tai, AH | 1 |
| Carnie, JA | 1 |
| Howland, BE | 1 |
| Zebrowski, EJ | 1 |
| Selye, H | 1 |
| Tuchweber, B | 1 |
| Gabbiani, G | 1 |
| Finkelstein, JD | 1 |
| Kyle, W | 1 |
| Harris, BJ | 1 |
Other Studies
18 other studies available for alloxan and Aging
| Article | Year |
|---|---|
Ultra-structural changes and apoptotic activity in cerebellum of post-menopausal-diabetic rats: a histochemical and ultra-structural study.
Topics: Aging; Alloxan; Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain Edema; Cerebellum; Diabetes | 2014 |
Long term evaluation of functional and morphological bladder alterations on alloxan-induced diabetes and aging: experimental study in rats.
Topics: Aging; Alloxan; Animals; Collagen; Cystotomy; Denervation; Diabetes Mellitus, Experimental; Disease | 2008 |
Histologic study of urethral extracellular matrix and collagen from aging and long-term alloxan-induced diabetic male rats.
Topics: Aging; Alloxan; Animals; Collagen; Diabetes Mellitus, Experimental; Extracellular Matrix; Male; Rats | 2011 |
Adaptive responses to alloxan-induced mild oxidative stress ameliorate certain tauopathy phenotypes.
Topics: Acetylation; Adaptation, Physiological; Aging; Alloxan; Animals; Disease Models, Animal; Female; His | 2012 |
[The breakdown of radiophosphorus into electrophoretically separable phosphate fractions by the lens, relative to age and to poisoning with naphthalene, dinitrophenol and alloxan].
Topics: Aging; Alloxan; Animals; Cataract; Diabetes Mellitus, Experimental; Dinitrophenols; Lens, Crystallin | 1955 |
[Role of the higher segments of the central nervous system, of the growth factor and of the sex hormones in the pathogenesis of experimental (alloxan) diabetes].
Topics: Aging; Alloxan; Animals; Central Nervous System; Diabetes Mellitus, Experimental; Gonadal Steroid Ho | 1959 |
Age-related differences in the degree of lipid peroxidation and state of antioxidant protection under the influence of alloxan.
Topics: Aging; Alloxan; Animals; Antioxidants; Diabetes Mellitus, Experimental; Hyperglycemia; Hyperlipidemi | 2005 |
The diabetogenic effects of streptozotocin in mice are prolonged and inversely related to age.
Topics: Aging; Alloxan; Animals; Diabetes Mellitus, Experimental; Fluorescent Antibody Technique; Glucose To | 1981 |
Sequential changes in serum glucose, triglycerides and cholesterol in aging of normal and alloxan-diabetic rats.
Topics: Aging; Alloxan; Animals; Blood Glucose; Body Weight; Cholesterol; Creatinine; Diabetes Mellitus, Exp | 1981 |
A new diabetes model induced by neonatal alloxan treatment in rats.
Topics: Acetylglucosaminidase; Aging; Alloxan; Animals; Animals, Newborn; Blood Glucose; Body Weight; Diabet | 1993 |
Alloxan diabetes regulates adenosine deaminase activity in mice: tissue- and age-specific correlation.
Topics: Adenosine Deaminase; Aging; Alloxan; Animals; Diabetes Mellitus, Experimental; Female; Intestine, Sm | 1998 |
Effect of methylene blue and cobaltous chloride on the alloxan-induced changes in collagen characteristics in the skin of garden lizard Calotes versicolor.
Topics: Aging; Alloxan; Animals; Cobalt; Collagen; Drug Interactions; Lizards; Methylene Blue; Skin | 1989 |
Alloxan-induced changes in the collagen characteristics in the skin of male garden lizards, Calotes versicolor, from three age groups.
Topics: Aging; Alloxan; Animals; Blood Glucose; Body Weight; Collagen; Diabetes Mellitus, Experimental; Live | 1986 |
Lipids in tissues of the eye. V. Phospholipid metabolism in normal and cataractous lens.
Topics: Aging; Albumins; Alcohols; Alloxan; Animals; Cataract; Cattle; Cytosine Nucleotides; Diabetes Mellit | 1971 |
Increased liver L-serine-pyruvate aminotransferase activity under gluconeogenic conditions.
Topics: Aging; Alloxan; Animals; Animals, Newborn; Female; Fetus; Glucagon; Gluconeogenesis; L-Serine Dehydr | 1973 |
Serum and pituitary gonadotropin levels in alloxan-diabetic rats.
Topics: Aging; Alloxan; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response | 1974 |
[Clinical implications of calciphylaxis].
Topics: Aged; Aging; Alloxan; Aluminum; Animals; Autonomic Nervous System; Calciphylaxis; Dextrans; Haplorhi | 1969 |
Methionine metabolism in mammals. Regulation of homocysteine methyltransferases in rat tissue.
Topics: Aging; Alloxan; Animals; Betaine; Chromatography, Gel; Cycloheximide; Cysteine; Dactinomycin; Dietar | 1971 |