allopurinol and Osteochondritis-Dissecans

Joint pain is a common complaint in pediatrics and is most often attributed to overuse or injury. In the face of persistent, severe, or recurrent symptoms, the differential typically expands to include bony or structural causes versus rheumatologic conditions. Rarely, a child has two distinct causes for joint pain. In this case, an obese 15-year-old male was diagnosed with gout, a disease common in adults but virtually ignored in the field of pediatrics. The presence of juvenile idiopathic arthritis (JIA) complicated and delayed the consideration of this second diagnosis. Indeed, the absence of gout from this patient's differential diagnosis resulted in a greater than two-year delay in receiving treatment. The patients' BMI was 47.4, and he was also mis-diagnosed with osteochondritis dissecans and underwent medical treatment for JIA, assorted imaging studies, and multiple surgical procedures before the key history of increased pain with red meat ingestion, noticed by the patient, and a subsequent elevated uric acid confirmed his ultimate diagnosis. With the increased prevalence of obesity in the adolescent population, the diagnosis of gout should be an important consideration in the differential diagnosis for an arthritic joint in an overweight patient, regardless of age.

Topics: Adolescent; Allopurinol; Ankle Joint; Arthritis, Gouty; Arthritis, Juvenile; Colchicine; Delayed Diagnosis; Diagnosis, Differential; Gout Suppressants; Humans; Magnetic Resonance Imaging; Male; Obesity; Orthopedic Procedures; Osteochondritis Dissecans; Severity of Illness Index; Time-to-Treatment; Treatment Failure; Uric Acid