Page last updated: 2024-10-16

allantoin and Inflammation

allantoin has been researched along with Inflammation in 12 studies

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to evaluate and compare the postoperative effect of a topic gel containing chlorhexidine, chitosan, allantoine and dexpanthenol versus a placebo for pain and inflammation control after third molar surgery."9.34Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial. ( Bornstein, MM; González-Serrano, J; López-Quiles, J; Molinero-Mourelle, P; Rubio-Alonso, L; Sáez-Alcaide, LM, 2020)
" After ET administration, some decreasing trends were seen in biomarkers of oxidative damage and inflammation, including allantoin (urate oxidation), 8-hydroxy-2'-deoxyguanosine (DNA damage), 8-iso-PGF2α (lipid peroxidation), protein carbonylation, and C-reactive protein."7.85Administration of Pure Ergothioneine to Healthy Human Subjects: Uptake, Metabolism, and Effects on Biomarkers of Oxidative Damage and Inflammation. ( Cheah, IK; Halliwell, B; Lim, KH; Tang, RM; Yew, TS, 2017)
"24; p < 0."6.80Efficacy of chlorhexidine, dexpanthenol, allantoin and chitosan gel in comparison with bicarbonate oral rinse in controlling post-interventional inflammation, pain and cicatrization in subjects undergoing dental surgery. ( Estrugo-Devesa, A; González-Navarro, B; Jan-Pallí, E; Jané-Salas, E; lez-Navarro, BG; Lope-Lopez, J; Lopez-Lopez, J; Milani, M, 2015)
"The aim of this study was to evaluate and compare the postoperative effect of a topic gel containing chlorhexidine, chitosan, allantoine and dexpanthenol versus a placebo for pain and inflammation control after third molar surgery."5.34Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial. ( Bornstein, MM; González-Serrano, J; López-Quiles, J; Molinero-Mourelle, P; Rubio-Alonso, L; Sáez-Alcaide, LM, 2020)
"Amelioration of both oxidative and inflammation status after cholesterol lowering treatment in CKD might be mediated by restoration of antioxidant taurine concentrations during therapy (from 51."5.20Impact of cholesterol lowering treatment on plasma kynurenine and tryptophan concentrations in chronic kidney disease: relationship with oxidative stress improvement. ( Carru, C; Mangoni, AA; Sanna, M; Satta, AE; Sotgia, S; Zinellu, A, 2015)
" After ET administration, some decreasing trends were seen in biomarkers of oxidative damage and inflammation, including allantoin (urate oxidation), 8-hydroxy-2'-deoxyguanosine (DNA damage), 8-iso-PGF2α (lipid peroxidation), protein carbonylation, and C-reactive protein."3.85Administration of Pure Ergothioneine to Healthy Human Subjects: Uptake, Metabolism, and Effects on Biomarkers of Oxidative Damage and Inflammation. ( Cheah, IK; Halliwell, B; Lim, KH; Tang, RM; Yew, TS, 2017)
" Plasma MED concentrations, inflammation and oxidative stress indices [Kynurenine/Tryptophan (Kyn/Trp) ratio, malondialdehyde (MDA) and allantoin/uric acid (All/UA) ratio] were measured in 30 CKD patients randomized to three cholesterol lowering regimens for 12 months (simvastatin 40mg/day, ezetimibe/simvastatin 10/20mg/day, or ezetimibe/simvastatin 10/40mg/day)."3.83Effect of cholesterol lowering treatment on plasma markers of endothelial dysfunction in chronic kidney disease. ( Carru, C; Ena, S; Mangoni, AA; Satta, AE; Sotgia, S; Sotgiu, E; Zinellu, A, 2016)
"24; p < 0."2.80Efficacy of chlorhexidine, dexpanthenol, allantoin and chitosan gel in comparison with bicarbonate oral rinse in controlling post-interventional inflammation, pain and cicatrization in subjects undergoing dental surgery. ( Estrugo-Devesa, A; González-Navarro, B; Jan-Pallí, E; Jané-Salas, E; lez-Navarro, BG; Lope-Lopez, J; Lopez-Lopez, J; Milani, M, 2015)
"Comfrey has a centuries-old tradition as a medicinal plant."2.48Comfrey: a clinical overview. ( Staiger, C, 2012)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's9 (75.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Sáez-Alcaide, LM1
Molinero-Mourelle, P1
González-Serrano, J1
Rubio-Alonso, L1
Bornstein, MM1
López-Quiles, J1
Dickerhof, N1
Pearson, JF1
Hoskin, TS1
Berry, LJ1
Turner, R2
Sly, PD1
Kettle, AJ2
Zinellu, A2
Sotgia, S2
Mangoni, AA2
Sanna, M1
Satta, AE2
Carru, C2
Lopez-Lopez, J1
Lope-Lopez, J1
Jan-Pallí, E1
lez-Navarro, BG1
González-Navarro, B1
Jané-Salas, E1
Estrugo-Devesa, A1
Milani, M1
Sotgiu, E1
Ena, S1
Cheah, IK1
Tang, RM1
Yew, TS1
Lim, KH1
Halliwell, B1
Meotti, FC1
Jameson, GN1
Harwood, DT1
Stockwell, S1
Rees, MD1
Thomas, SR1
Staiger, C1
Araújo, LU1
Reis, PG1
Barbosa, LC1
Saúde-Guimarães, DA1
Grabe-Guimarães, A1
Mosqueira, VC1
Carneiro, CM1
Silva-Barcellos, NM1
Becker, BF1
Kastenbauer, S1
Ködel, U1
Kiesl, D1
Pfister, HW1
Jonas, FJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Investigating the Efficacy of Ergothioneine to Delay Cognitive Decline in Mild Cognitively Impaired Subjects[NCT03641404]Phase 3106 participants (Anticipated)Interventional2018-08-31Not yet recruiting
The Effects of Daily Anti-inflammatory Supplementation on Foundation Pain Index Scores in Chronic Opiate Patients[NCT05896878]20 participants (Anticipated)Interventional2023-07-10Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for allantoin and Inflammation

ArticleYear
Comfrey: a clinical overview.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:10

    Topics: Allantoin; Analgesics; Anti-Inflammatory Agents; Cinnamates; Comfrey; Depsides; Humans; Inflammation

2012

Trials

3 trials available for allantoin and Inflammation

ArticleYear
Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial.
    Medicina oral, patologia oral y cirugia bucal, 2020, Sep-01, Volume: 25, Issue:5

    Topics: Allantoin; Chitosan; Chlorhexidine; Double-Blind Method; Edema; Humans; Inflammation; Molar, Third;

2020
Impact of cholesterol lowering treatment on plasma kynurenine and tryptophan concentrations in chronic kidney disease: relationship with oxidative stress improvement.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2015, Volume: 25, Issue:2

    Topics: Aged; Allantoin; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Res

2015
Efficacy of chlorhexidine, dexpanthenol, allantoin and chitosan gel in comparison with bicarbonate oral rinse in controlling post-interventional inflammation, pain and cicatrization in subjects undergoing dental surgery.
    Current medical research and opinion, 2015, Volume: 31, Issue:12

    Topics: Adult; Allantoin; Analgesics; Bicarbonates; Chitosan; Chlorhexidine; Cicatrix; Cross-Over Studies; F

2015

Other Studies

8 other studies available for allantoin and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Oxidative stress in early cystic fibrosis lung disease is exacerbated by airway glutathione deficiency.
    Free radical biology & medicine, 2017, Volume: 113

    Topics: Age of Onset; Allantoin; Bronchiectasis; Bronchoalveolar Lavage Fluid; Case-Control Studies; Child;

2017
Effect of cholesterol lowering treatment on plasma markers of endothelial dysfunction in chronic kidney disease.
    Journal of pharmaceutical and biomedical analysis, 2016, Sep-10, Volume: 129

    Topics: Allantoin; Anticholesteremic Agents; Arginine; Biomarkers; Cholesterol; Endothelium; Ezetimibe; Fema

2016
Administration of Pure Ergothioneine to Healthy Human Subjects: Uptake, Metabolism, and Effects on Biomarkers of Oxidative Damage and Inflammation.
    Antioxidants & redox signaling, 2017, 02-10, Volume: 26, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Allantoin; Antioxidants; Betaine; Biomarkers; C-Reactive Protein; Deoxy

2017
Administration of Pure Ergothioneine to Healthy Human Subjects: Uptake, Metabolism, and Effects on Biomarkers of Oxidative Damage and Inflammation.
    Antioxidants & redox signaling, 2017, 02-10, Volume: 26, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Allantoin; Antioxidants; Betaine; Biomarkers; C-Reactive Protein; Deoxy

2017
Administration of Pure Ergothioneine to Healthy Human Subjects: Uptake, Metabolism, and Effects on Biomarkers of Oxidative Damage and Inflammation.
    Antioxidants & redox signaling, 2017, 02-10, Volume: 26, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Allantoin; Antioxidants; Betaine; Biomarkers; C-Reactive Protein; Deoxy

2017
Administration of Pure Ergothioneine to Healthy Human Subjects: Uptake, Metabolism, and Effects on Biomarkers of Oxidative Damage and Inflammation.
    Antioxidants & redox signaling, 2017, 02-10, Volume: 26, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Allantoin; Antioxidants; Betaine; Biomarkers; C-Reactive Protein; Deoxy

2017
Urate as a physiological substrate for myeloperoxidase: implications for hyperuricemia and inflammation.
    The Journal of biological chemistry, 2011, Apr-15, Volume: 286, Issue:15

    Topics: Allantoin; Cardiovascular Diseases; Humans; Hydrogen Peroxide; Hyperuricemia; Inflammation; NADPH Ox

2011
In vivo wound healing effects of Symphytum officinale L. leaves extract in different topical formulations.
    Die Pharmazie, 2012, Volume: 67, Issue:4

    Topics: Administration, Topical; Allantoin; Animals; Chemistry, Pharmaceutical; Comfrey; Emulsions; Female;

2012
Urate oxidation in CSF and blood of patients with inflammatory disorders of the nervous system.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

    Topics: Allantoin; Blood-Brain Barrier; Brain; Central Nervous System Diseases; Guillain-Barre Syndrome; Hum

2004
[Experiences on the use of medicinal plant extracts for traumatic and inflammatory swelling of the soft tissue].
    Deutsches medizinisches Journal, 1966, Oct-05, Volume: 17, Issue:19

    Topics: Allantoin; Choline; Humans; Hydantoins; Inflammation; Plants, Medicinal; Wounds and Injuries

1966