allantoin has been researched along with Cicatrix in 20 studies
Cicatrix: The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study was designed to investigate whether local administration of a mixture composed of cepae extract, allantoin, and heparin (CAH) decreased already formed epidural fibrosis (EF) at the laminectomy site." | 7.83 | Effects of cepae extract, allantoin, and heparin mixture on developing andalready formed epidural fibrosis in a rat laminectomy model. ( Aktaş, A; Çetinalp, NE; Özay, R; Özdemir, HM; Şekerci, Z; Yavuz, OY; Yiğit, F, 2016) |
| "24; p < 0." | 6.80 | Efficacy of chlorhexidine, dexpanthenol, allantoin and chitosan gel in comparison with bicarbonate oral rinse in controlling post-interventional inflammation, pain and cicatrization in subjects undergoing dental surgery. ( Estrugo-Devesa, A; González-Navarro, B; Jan-Pallí, E; Jané-Salas, E; lez-Navarro, BG; Lope-Lopez, J; Lopez-Lopez, J; Milani, M, 2015) |
| "The study was designed to investigate whether local administration of a mixture composed of cepae extract, allantoin, and heparin (CAH) decreased already formed epidural fibrosis (EF) at the laminectomy site." | 3.83 | Effects of cepae extract, allantoin, and heparin mixture on developing andalready formed epidural fibrosis in a rat laminectomy model. ( Aktaş, A; Çetinalp, NE; Özay, R; Özdemir, HM; Şekerci, Z; Yavuz, OY; Yiğit, F, 2016) |
| "24; p < 0." | 2.80 | Efficacy of chlorhexidine, dexpanthenol, allantoin and chitosan gel in comparison with bicarbonate oral rinse in controlling post-interventional inflammation, pain and cicatrization in subjects undergoing dental surgery. ( Estrugo-Devesa, A; González-Navarro, B; Jan-Pallí, E; Jané-Salas, E; lez-Navarro, BG; Lope-Lopez, J; Lopez-Lopez, J; Milani, M, 2015) |
| "A topical scar gel containing extract of Allium cepae, allantoin and heparin (Contractubex®; Merz Pharmaceuticals GmbH, Germany), has shown efficacy in improving the appearance of various scar types." | 2.79 | The prophylactic use of a topical scar gel containing extract of Allium cepae, allantoin, and heparin improves symptoms and appearance of cesarean-section scars compared with untreated scars. ( Acker, C; Buske, K; Iglesias Benavides, JL; Lehn, A; Ocampo-Candiani, J; Vázquez-Martínez, OT, 2014) |
| "Contractubex gel is effective in scar prevention in Chinese patients having laser removal of tattoos." | 2.72 | Use of onion extract, heparin, allantoin gel in prevention of scarring in chinese patients having laser removal of tattoos: a prospective randomized controlled trial. ( Chan, HH; Chan, PC; Ho, WS; Ying, SY, 2006) |
| "Additionally, the scars were characterized after a six-month treatment-free follow-up period." | 2.68 | Possibilities of scar treatment after thoracic surgery. ( Görtelmeyer, R; Maragakis, M; Michel, G; Willital, GH, 1995) |
| "The appearance of the scar, including scar type and scar size as well as scar colour, was assessed by the physician." | 2.67 | Efficacy of Contractubex gel in the treatment of fresh scars after thoracic surgery in children and adolescents. ( Heine, H; Willital, GH, 1994) |
| "Cutaneous scars (particularly hypertrophic and keloid scars), not only can cause adverse cosmetic problems, but also can be associated with emotional distress such as anxiety and depression." | 2.55 | The Effectiveness of Topical Anti-scarring Agents and a Novel Combined Process on Cutaneous Scar Management. ( Chen, CY; Fang, QQ; Huang, CL; Tan, WQ; Wang, XW; Wu, LH; Xu, JH; Zhang, LY; Zhang, MX, 2017) |
| "Parameters measured included scar size, color, and pliability (consistency/hardness), as well as patients' and physicians' subjective assessments of treatment efficacy and tolerability." | 1.39 | Efficacy of early initiation of a gel containing extractum cepae, heparin, and allantoin for scar treatment: an observational, noninterventional study of daily practice. ( Simon, J; Willital, GH, 2013) |
| "On the 30th day, scar tissues were excised to investigate the immunohistochemical and ultrastructural effects of these agents." | 1.38 | Comparison of the effects of Contractubex® gel in an experimental model of scar formation in rats: an immunohistochemical and ultrastructural study. ( Bilac, C; Giray, G; Guzel, E; Inan, S; Muftuoglu, S; Ozturkcan, S; Sahin, MT, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 10 (50.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ozay, R | 2 |
| Keskin, E | 1 |
| Balkan, MS | 1 |
| Aktas, A | 2 |
| Akturk, UD | 1 |
| Esener, O | 1 |
| Akturk, T | 1 |
| Hanalioglu, S | 1 |
| Atabey, C | 1 |
| Sekerci, Z | 2 |
| Gonchakov, GV | 1 |
| Merkulova, YA | 1 |
| Prager, W | 1 |
| Gauglitz, GG | 1 |
| Ocampo-Candiani, J | 1 |
| Vázquez-Martínez, OT | 1 |
| Iglesias Benavides, JL | 1 |
| Buske, K | 1 |
| Lehn, A | 1 |
| Acker, C | 1 |
| Kerwin, LY | 1 |
| El Tal, AK | 1 |
| Stiff, MA | 1 |
| Fakhouri, TM | 1 |
| Lopez-Lopez, J | 1 |
| Lope-Lopez, J | 1 |
| Jan-Pallí, E | 1 |
| lez-Navarro, BG | 1 |
| González-Navarro, B | 1 |
| Jané-Salas, E | 1 |
| Estrugo-Devesa, A | 1 |
| Milani, M | 1 |
| Yavuz, OY | 1 |
| Yiğit, F | 1 |
| Çetinalp, NE | 1 |
| Özdemir, HM | 1 |
| Fang, QQ | 1 |
| Chen, CY | 1 |
| Zhang, MX | 1 |
| Huang, CL | 1 |
| Wang, XW | 1 |
| Xu, JH | 1 |
| Wu, LH | 1 |
| Zhang, LY | 1 |
| Tan, WQ | 1 |
| Stozkowska, W | 2 |
| Raczyńska, K | 1 |
| Aysan, E | 1 |
| Bektas, H | 1 |
| Ersoz, F | 1 |
| Sari, S | 1 |
| Huq, G | 1 |
| Calka, O | 1 |
| Omer, C | 1 |
| Akdeniz, N | 1 |
| Necmettin, A | 1 |
| Özkol, HU | 1 |
| Ozkol Hatice, U | 1 |
| Karadag, AS | 1 |
| Serap, KA | 1 |
| Behçet, L | 1 |
| Lütfi, B | 1 |
| Sahin, MT | 1 |
| Inan, S | 1 |
| Ozturkcan, S | 1 |
| Guzel, E | 1 |
| Bilac, C | 1 |
| Giray, G | 1 |
| Muftuoglu, S | 1 |
| Willital, GH | 3 |
| Simon, J | 1 |
| CAHEN, R | 1 |
| PESSONNIER, A | 1 |
| Ho, WS | 1 |
| Ying, SY | 1 |
| Chan, PC | 1 |
| Chan, HH | 1 |
| Janicki, S | 2 |
| Jaśkowski, J | 1 |
| Kasprzak, A | 1 |
| Kondrat, W | 1 |
| Heine, H | 1 |
| Maragakis, M | 1 |
| Michel, G | 1 |
| Görtelmeyer, R | 1 |
| de Buman, M | 1 |
| Walther, M | 1 |
| de Weck, R | 1 |
| Sznitowska, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness and Tolerability of an Overnight 4-week Treatment With Patch Containing Onion Extract and Allantoin for Cesarean Section Scars[NCT04046783] | 93 participants (Actual) | Observational | 2019-03-02 | Completed | |||
| A Prospective, Single-center, Randomized, Parallel Group Trial to Investigate the Efficacy of Contractubex® Gel, Containing Extractum Cepae, Allantoin, and Heparin, in Scars After Abdominal Caesarean Section[NCT01112371] | Phase 4 | 61 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
| The Role of 5-Fluorouracil in Post-Operative Scar Formation Following Direct Brow Ptosis Repair[NCT03219580] | Phase 3 | 50 participants (Anticipated) | Interventional | 2017-05-20 | Enrolling by invitation | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for allantoin and Cicatrix
| Article | Year |
|---|---|
Scar prevention and remodeling: a review of the medical, surgical, topical and light treatment approaches.
Topics: Administration, Cutaneous; Allantoin; Antimitotic Agents; Botulinum Toxins, Type A; Cicatrix; Dermab | 2014 |
The Effectiveness of Topical Anti-scarring Agents and a Novel Combined Process on Cutaneous Scar Management.
Topics: Administration, Topical; Allantoin; Cicatrix; Drug Combinations; Heparin; Ointments; Plant Extracts; | 2017 |
The Effectiveness of Topical Anti-scarring Agents and a Novel Combined Process on Cutaneous Scar Management.
Topics: Administration, Topical; Allantoin; Cicatrix; Drug Combinations; Heparin; Ointments; Plant Extracts; | 2017 |
The Effectiveness of Topical Anti-scarring Agents and a Novel Combined Process on Cutaneous Scar Management.
Topics: Administration, Topical; Allantoin; Cicatrix; Drug Combinations; Heparin; Ointments; Plant Extracts; | 2017 |
The Effectiveness of Topical Anti-scarring Agents and a Novel Combined Process on Cutaneous Scar Management.
Topics: Administration, Topical; Allantoin; Cicatrix; Drug Combinations; Heparin; Ointments; Plant Extracts; | 2017 |
[Efficiency and application safety of Cepan cream. Observation of a new indication].
Topics: Allantoin; Animals; Blepharitis; Burns; Chamomile; Cicatrix; Drug Combinations; Drug Synergism; Eyel | 2008 |
8 trials available for allantoin and Cicatrix
| Article | Year |
|---|---|
[Evaluation of advantages of Contractubex gel usage for postsurgical scars treatment in comparison with absence of systematized topical scars treatment of kids with congenital cleft lip and palate].
Topics: Allantoin; Cicatrix; Cleft Lip; Cleft Palate; Dermatologic Agents; Drug Combinations; Gels; Heparin; | 2020 |
Effectiveness and Safety of an Overnight Patch Containing Allium cepa Extract and Allantoin for Post-Dermatologic Surgery Scars.
Topics: Adult; Aged; Aged, 80 and over; Allantoin; Cicatrix; Dermatologic Agents; Dermatologic Surgical Proc | 2018 |
The prophylactic use of a topical scar gel containing extract of Allium cepae, allantoin, and heparin improves symptoms and appearance of cesarean-section scars compared with untreated scars.
Topics: Administration, Cutaneous; Adolescent; Adult; Allantoin; Cesarean Section; Cicatrix; Drug Combinatio | 2014 |
Efficacy of chlorhexidine, dexpanthenol, allantoin and chitosan gel in comparison with bicarbonate oral rinse in controlling post-interventional inflammation, pain and cicatrization in subjects undergoing dental surgery.
Topics: Adult; Allantoin; Analgesics; Bicarbonates; Chitosan; Chlorhexidine; Cicatrix; Cross-Over Studies; F | 2015 |
Use of onion extract, heparin, allantoin gel in prevention of scarring in chinese patients having laser removal of tattoos: a prospective randomized controlled trial.
Topics: Adult; Allantoin; Cicatrix; Drug Combinations; Female; Gels; Heparin; Humans; Laser Therapy; Male; O | 2006 |
Efficacy of Contractubex gel in the treatment of fresh scars after thoracic surgery in children and adolescents.
Topics: Administration, Topical; Adolescent; Allantoin; Allium; Child; Child, Preschool; Cicatrix; Dermatolo | 1994 |
Possibilities of scar treatment after thoracic surgery.
Topics: Administration, Topical; Adolescent; Allantoin; Child; Child, Preschool; Cicatrix; Dermatologic Agen | 1995 |
[Effectiveness of Alphastria cream in the prevention of pregnancy stretch marks (striae distensae). Results of a double-blind study].
Topics: Allantoin; Cicatrix; Clinical Trials as Topic; Dermatologic Agents; Double-Blind Method; Drug Combin | 1987 |
9 other studies available for allantoin and Cicatrix
| Article | Year |
|---|---|
Effects of Topically Applied Contractubex® on Epidural Fibrosis and Axonal Regeneration in Injured Rat Sciatic Nerve.
Topics: Allantoin; Animals; Cicatrix; Male; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2023 |
Effects of cepae extract, allantoin, and heparin mixture on developing andalready formed epidural fibrosis in a rat laminectomy model.
Topics: Allantoin; Animals; Cicatrix; Epidural Space; Fibrosis; Heparin; Laminectomy; Male; Rats; Rats, Spra | 2016 |
Effects of contractubex on the prevention of postoperative peritoneal adhesion.
Topics: Allantoin; Animals; Cicatrix; Drug Combinations; Female; Heparin; Humans; Keloid; Peritoneal Cavity; | 2010 |
Irritant contact dermatitis caused by Ranunculus kotschyi Boiss in 6 cases.
Topics: Adult; Aged; Allantoin; Anti-Bacterial Agents; Anti-Inflammatory Agents; Arthralgia; Betamethasone; | 2011 |
Comparison of the effects of Contractubex® gel in an experimental model of scar formation in rats: an immunohistochemical and ultrastructural study.
Topics: Administration, Topical; Allantoin; Animals; Cicatrix; Disease Models, Animal; Drug Combinations; Fe | 2012 |
Efficacy of early initiation of a gel containing extractum cepae, heparin, and allantoin for scar treatment: an observational, noninterventional study of daily practice.
Topics: Adult; Allantoin; Cicatrix; Cohort Studies; Color; Dermatologic Agents; Diagnostic Self Evaluation; | 2013 |
[Study of dihydroxyaluminum allantoinate and chlorhydroxyaluminum allantoinate. V. Effect on cicatrization of gastric ulcer].
Topics: Allantoin; Aluminum Hydroxide; Antacids; Bismuth; Cicatrix; Histamine; Reserpine; Stomach Ulcer | 1963 |
[Technology and preliminary evaluation of ointments that increase the elasticity of post-burn scars].
Topics: Adolescent; Adult; Allantoin; Burns; Chamomile; Child; Child, Preschool; Cicatrix; Dermatologic Agen | 1984 |
The effect of vehicle on allantoin penetration into human skin from an ointment for improving scar elasticity.
Topics: Allantoin; Cicatrix; Elasticity; Female; Gels; Humans; Male; Ointment Bases; Ointments; Pharmaceutic | 1988 |