alkenes and Disease Models, Animal

Topics: Acute Disease; Alkenes; Angiogenesis Inducing Agents; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Female; Male; Myocardial Infarction; Polyphenols; Rats; Rats, Sprague-Dawley; Swine

Topics: Alkenes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Differentiation; Cinnamates; Dementia, Vascular; Depsides; Disease Models, Animal; Gene Expression Regulation; Humans; Lactates; Neural Stem Cells; Neurons; Neuroprotective Agents; Nootropic Agents; Polyphenols; Rosmarinic Acid; Stroke; tau Proteins

Topics: Alkenes; Animals; Antiviral Agents; Chlorocebus aethiops; Disease Models, Animal; Drug Discovery; High-Throughput Screening Assays; Lactones; Lung; Mice; Mice, Inbred BALB C; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Specific Pathogen-Free Organisms; Vero Cells; Virus Replication

Topics: Acyclic Monoterpenes; Adrenalectomy; Alkenes; Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Catalase; Cell Adhesion Molecules; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Glutathione; Immunologic Factors; Inflammation; Kidney; Lipid Peroxidation; Male; Nitric Oxide Synthase Type II; Oxidative Stress; Rats, Wistar; Superoxide Dismutase

Topics: Alkenes; Amino Acid Transport System ASC; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Brain Ischemia; Calcium-Binding Proteins; Caspase 1; Cell Survival; Cells, Cultured; Disease Models, Animal; Inflammasomes; Injections, Intraperitoneal; Interleukin-1beta; Intracellular Signaling Peptides and Proteins; Male; Microfilament Proteins; Microglia; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphate-Binding Proteins; Polyphenols; Pyroptosis; Rats, Sprague-Dawley; Reperfusion Injury

Topics: Administration, Oral; Alkenes; Animals; Biological Availability; Brain Infarction; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Compounding; Emulsifying Agents; Emulsions; Hematologic Diseases; Hemorheology; Humans; Hydrophobic and Hydrophilic Interactions; Injections, Intravenous; Male; Oils; Particle Size; Polyphenols; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Water

Topics: Acute Kidney Injury; Alkenes; Animals; Apoptosis; Biomarkers; Blood Urea Nitrogen; Carrier Proteins; Cell Line; Creatinine; Cytoprotection; Disease Models, Animal; Humans; Intracellular Signaling Peptides and Proteins; Kidney; Male; Oxidative Stress; Phosphoproteins; Phosphorylation; Polyphenols; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Renal Agents; Reperfusion Injury; Signal Transduction; TOR Serine-Threonine Kinases

Topics: Alkenes; Animals; Antigens, CD; Astragalus Plant; Brain; Brain Edema; Cadherins; Carotid Artery Thrombosis; Cell Adhesion Molecules; Cerebrovascular Circulation; Claudin-5; Collagen Type IV; Disease Models, Animal; Drug Combinations; Drugs, Chinese Herbal; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex IV; Intracranial Hemorrhages; Laminin; Male; Mice; Occludin; Panax notoginseng; Polyphenols; Receptors, Cell Surface; Reperfusion Injury; Saponins; Tissue Plasminogen Activator; Zonula Occludens-1 Protein

Topics: Alkenes; Anaphylaxis; Animals; Calcium Signaling; Cell Degranulation; Disease Models, Animal; HEK293 Cells; Humans; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Docking Simulation; Phospholipase C gamma; Polyphenols; Receptors, G-Protein-Coupled; RNA, Small Interfering; Signal Transduction

Topics: Alkenes; Animals; Disease Models, Animal; Intervertebral Disc Degeneration; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Nucleus Pulposus; Polyphenols; Rabbits; Regeneration

Topics: Acetaminophen; Alkenes; Animals; Anti-Inflammatory Agents; Apoptosis; Chemical and Drug Induced Liver Injury; Cytokines; Disease Models, Animal; Heme Oxygenase-1; Humans; Inflammation; Inflammation Mediators; Kelch-Like ECH-Associated Protein 1; Male; Membrane Proteins; Mice; Mice, Inbred ICR; NF-E2-Related Factor 2; Oxidative Stress; Polyphenols; Salvia miltiorrhiza; Signal Transduction

Topics: Alkenes; Animals; Antidepressive Agents; Corticosterone; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Hindlimb Suspension; Hippocampus; Illicium; Male; Mice; Mice, Inbred ICR; Phenols; Prefrontal Cortex; Serotonin; Stress, Psychological; Swimming; Time Factors

Topics: Alkenes; Animals; Annonaceae; Anti-Ulcer Agents; Antioxidants; bcl-2-Associated X Protein; Cyclooxygenase 2; Disease Models, Animal; Ethanol; Gastric Mucosa; Glutathione; Helicobacter Infections; Helicobacter pylori; Hemorrhage; HSP70 Heat-Shock Proteins; Ketones; Male; Malondialdehyde; Nitric Oxide; Phytotherapy; Plant Extracts; Rats; Stomach Ulcer; Sulfhydryl Compounds

Topics: Acute Disease; Alkenes; Amylases; Animals; Biomarkers; Ceruletide; Disease Models, Animal; Dose-Response Relationship, Drug; Exocrine Pancreatic Insufficiency; Lipase; Male; MicroRNAs; Nitriles; Pancreas; Rats; Rats, Sprague-Dawley

Topics: Alkenes; Animals; Axons; Blotting, Western; Brain; Disease Models, Animal; Epilepsy; Humans; Immunohistochemistry; Interneurons; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microscopy, Confocal; Mutation; Piperidines; Voltage-Gated Sodium Channel beta-1 Subunit

Topics: Alkenes; Animals; Brain Injuries; Carbon Monoxide; Carbon Monoxide Poisoning; Disease Models, Animal; Erythrocytes; Hematocrit; Hemorheology; Hippocampus; Humans; Malondialdehyde; Mannitol; Neurotoxicity Syndromes; Polyphenols; Rats

Topics: Alkenes; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Benzene Derivatives; Brain; Disease Models, Animal; Fluorescent Dyes; Humans; Imaging, Three-Dimensional; Mice, Inbred C57BL; Mice, Transgenic; Microscopy; Plaque, Amyloid; Stilbenes

Topics: Acyclic Monoterpenes; Adult; Alkenes; Animals; Annona; Antineoplastic Agents, Phytogenic; beta-Cyclodextrins; Bicyclic Monoterpenes; Cell Line, Tumor; Cyclohexane Monoterpenes; Cyclohexanones; Disease Models, Animal; Drug Compounding; Gas Chromatography-Mass Spectrometry; Hep G2 Cells; Humans; Inhibitory Concentration 50; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Monoterpenes; Oils, Volatile; Plant Leaves; Sesquiterpenes; Sesquiterpenes, Germacrane; Terpenes; Young Adult

Topics: Alkenes; Animals; Antidepressive Agents, Second-Generation; Chronic Disease; Cognition Disorders; Depressive Disorder; Disease Models, Animal; Drug Therapy, Combination; Fluoxetine; Male; Maze Learning; Polyphenols; Rats; Rats, Sprague-Dawley; Stress, Psychological

Topics: Administration, Intranasal; Alkenes; Animals; Antiviral Agents; Benzamides; Disease Models, Animal; Epithelial Cells; Humans; Hydrazines; Isoindoles; Lung; Macrophages, Alveolar; Mice; Mice, Inbred ICR; Smallpox; Variola virus; Viral Load; Virus Replication

Topics: Alkenes; Animals; Antibiotics, Antineoplastic; Apoptosis; Biomarkers; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mice; Phenols; Snail Family Transcription Factors; STAT3 Transcription Factor

Topics: Alkenes; Animals; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Inflammation; Interleukin-1beta; Interleukin-6; Male; Microglia; Neuroprotective Agents; NF-kappa B; Polyphenols; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Stroke; Toll-Like Receptor 4

Topics: Alkenes; Alzheimer Disease; Animals; Benzene Derivatives; Brain; Disease Models, Animal; Mice; Plaque, Amyloid; Stilbenes

Topics: Alkenes; Alzheimer Disease; Animals; Benzene Derivatives; Brain; Disease Models, Animal; Mice; Plaque, Amyloid; Stilbenes

Topics: Alkenes; Animals; Cyclic GMP; Disease Models, Animal; Ion Channels; Ischemic Preconditioning, Myocardial; Linoleic Acids; Male; Mitochondria, Heart; Mitochondrial ADP, ATP Translocases; Mitochondrial Proteins; Myocardial Reperfusion Injury; Nitric Oxide; Nitro Compounds; Rats; Rats, Sprague-Dawley; Uncoupling Protein 2

Topics: Age Factors; Alkenes; Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Animals; Antibodies; Benzene Derivatives; Calcium-Binding Proteins; Cell Count; Cell Movement; Cerebral Amyloid Angiopathy; CX3C Chemokine Receptor 1; Disease Models, Animal; Green Fluorescent Proteins; Leukocyte Common Antigens; Mice; Mice, Transgenic; Microfilament Proteins; Microglia; Plaque, Amyloid; Receptors, Chemokine; Stilbenes

Topics: Alkenes; Animals; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Magnetic Resonance Spectroscopy; Male; Metabolomics; Molecular Structure; Nitriles; Organ Size; Pancreas, Exocrine; Pancreatitis; Rats; Rats, Sprague-Dawley; Reference Standards

Topics: Alkenes; Animals; Benzofurans; Disease Models, Animal; Male; Mice; Nitric Oxide; Pain; Pain Measurement; Plant Bark; Plant Extracts; Primulaceae; Receptors, Adrenergic, alpha; Receptors, Serotonin; Signal Transduction

Topics: Alkenes; Amides; Animals; Antimalarials; Crystallography, X-Ray; Disease Models, Animal; Heterocyclic Compounds; Malaria; Mice; Models, Molecular; Molecular Structure; Oxidation-Reduction; Oxygen; Parasitic Sensitivity Tests; Plasmodium berghei; Propanols; Stereoisomerism; Sulfhydryl Compounds; Sulfides; Sulfones

Topics: Administration, Inhalation; Alkenes; Animals; Animals, Newborn; Disease Models, Animal; Drug Administration Schedule; Hypertension, Pulmonary; Nebulizers and Vaporizers; Nitric Oxide; Nitric Oxide Donors; Streptococcal Infections; Streptococcus agalactiae; Swine; Treatment Outcome

Topics: Alkenes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Edema; Humans; Hydroxamic Acids; Male; Molecular Structure; Nitric Oxide; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship

Topics: Alkenes; Animals; Creatine Kinase; Disease Models, Animal; Drugs, Chinese Herbal; Electrophoresis, Gel, Two-Dimensional; Male; Medicine, Chinese Traditional; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Panax notoginseng; Plants, Medicinal; Polyphenols; Proteomics; Rats; Rats, Wistar; Salvia miltiorrhiza; Saponins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors

Topics: Administration, Oral; Alkenes; Analgesics; Animals; Behavior, Animal; Benzofurans; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Injections, Intravenous; Interleukin-1beta; Mice; Motor Activity; Neuralgia; Neutrophil Infiltration; Pain; Pain Measurement; Pain Threshold; Peroxidase; Time Factors

Topics: Alkenes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzene; Benzene Derivatives; Binding, Competitive; Blood-Brain Barrier; Carbon Radioisotopes; Coloring Agents; Congo Red; Disease Models, Animal; Imaging, Three-Dimensional; Male; Mice; Mice, Transgenic; Microscopy; Peptide Fragments; Plaque, Amyloid; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Stilbenes

Topics: Aconitine; Alkenes; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Chloride; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Indoles; Lethal Dose 50; Male; Mice; Quaternary Ammonium Compounds; Rats

Topics: Acute Disease; Alkenes; Animals; Animals, Newborn; Blood Gas Analysis; Blood Pressure; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Nebulizers and Vaporizers; Nitric Oxide Donors; Random Allocation; Respiratory Function Tests; Swine

Topics: Alkenes; Amyloid beta-Peptides; Animals; Benzene Derivatives; Brain; Disease Models, Animal; Humans; Metabolic Clearance Rate; Mice; Plaque, Amyloid; Predictive Value of Tests; Prion Diseases; Reproducibility of Results; Scrapie; Stilbenes; Tomography, Emission-Computed

Topics: Alkenes; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Benzoates; Blood Vessels; Cerebral Amyloid Angiopathy; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peptide Fragments; Plaque, Amyloid

Topics: Alkenes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzene Derivatives; Cerebral Amyloid Angiopathy; Craniotomy; Disease Models, Animal; Disease Progression; Fluorescent Dyes; Humans; Image Processing, Computer-Assisted; Kinetics; Meninges; Mice; Mice, Transgenic; Plaque, Amyloid; Skin Window Technique; Stilbenes

Topics: Afferent Pathways; Alkenes; Animals; Capsaicin; Disease Models, Animal; Enzyme Inhibitors; Inflammation Mediators; Male; Nociceptors; Okadaic Acid; Pain; Pain Threshold; Phosphoprotein Phosphatases; Physical Stimulation; Polyenes; Posterior Horn Cells; Pyrones; Rats; Rats, Sprague-Dawley; Reaction Time; Synaptic Transmission; Time Factors

Topics: Acute Disease; Alkenes; Amylases; Animals; Biomarkers; Ceruletide; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Lipase; Male; Mice; Nitriles; Pancreas, Exocrine; Pancreatitis; Peptide Fragments; Predictive Value of Tests; Protein Array Analysis; Proteomics; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Severity of Illness Index; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors

Topics: Acute Disease; Alkenes; Animals; Biomarkers; Cells, Cultured; Cluster Analysis; Disease Models, Animal; Male; Nitriles; Pancreas, Exocrine; Pancreatitis; Peptide Fragments; Peptide Hydrolases; Predictive Value of Tests; Protein Array Analysis; Proteomics; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Sequence Analysis, Protein; Serum Albumin; Severity of Illness Index; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Trypsin

Topics: Acute Disease; Alkenes; Amylases; Animals; Apoptosis; Ceruletide; Disease Models, Animal; Female; Mice; Nitriles; Pancreas; Pancreatitis; Rats; Time Factors

Topics: Alkenes; Animals; Aorta, Thoracic; Arteriosclerosis; Cholesterol; Disease Models, Animal; Egg Yolk; Female; Propylamines; Rabbits

Topics: Administration, Oral; Alkenes; Animals; Carotenoids; Chemical Phenomena; Chemistry; Disease Models, Animal

Topics: Acetates; Alkenes; Animals; Animals, Laboratory; Behavior, Animal; Chemical Industry; Disease Models, Animal; Environmental Exposure; Humans; Male; Nicotine; Rats; Smoking; Social Behavior; Tape Recording; Toxicology; Vinyl Compounds