alisporivir has been researched along with Pneumonia--Viral* in 1 studies
1 other study(ies) available for alisporivir and Pneumonia--Viral
Article | Year |
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Inhibition of SARS-CoV-2 Infection by the Cyclophilin Inhibitor Alisporivir (Debio 025).
Cyclophilins play a key role in the life cycle of coronaviruses. Alisporivir (Debio 025) is a nonimmunosuppressive analogue of cyclosporine with potent cyclophilin inhibition properties. Alisporivir reduced SARS-CoV-2 RNA production in a dose-dependent manner in Vero E6 cells, with a 50% effective concentration (EC Topics: Animals; Antiviral Agents; Betacoronavirus; Cell Line; Chlorocebus aethiops; Coronavirus Infections; COVID-19; Cyclophilins; Cyclosporine; Humans; Pandemics; Pneumonia, Viral; SARS-CoV-2; Vero Cells; Virus Replication | 2020 |