Page last updated: 2024-10-22

alfuzosin and Ureteral Calculi

alfuzosin has been researched along with Ureteral Calculi in 13 studies

alfuzosin: structure given in first source

Ureteral Calculi: Stones in the URETER that are formed in the KIDNEY. They are rarely more than 5 mm in diameter for larger renal stones cannot enter ureters. They are often lodged at the ureteral narrowing and can cause excruciating renal colic.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study is to evaluate the efficacy of alfuzosin with methylprednisolone on expulsion and pain control of lower ureteral stones <10 mm in size."7.78Effects of alfuzosin with methylprednisolone for spontaneous expulsion and pain control of lower ureteral stone. ( Hwang, EC; Hwang, IS; Jung, SI; Kang, TW; Kim, MK; Kim, SO; Kwon, DD; Lu, JW; Park, K; Ryu, SB; Yu, HS, 2012)
"To assess the spontaneous passage rate for patients being treated with alfuzosin 10mg daily after presenting with an acute ureteral stone compared with a control group, and to assess the respective pain control status."5.15Medical expulsive therapy using alfuzosin for patient presenting with ureteral stone less than 10mm: a prospective randomized controlled trial. ( Chau, LH; Fan, CW; Fung, BT; Li, JC; Li, MK; Tai, DC, 2011)
"Medical treatment of lower ureteral calculi with tamsulosin and alfuzosin resulted in a significantly increased stone expulsion rate, decreased expulsion time, and a reduced need for analgesic therapy."5.14Prospective randomized trial comparing efficacy of alfuzosin and tamsulosin in management of lower ureteral stones. ( Agrawal, A; Agrawal, M; Gupta, A; Gupta, M; Lavania, P; Sarkari, A, 2009)
"This study shows that alfuzosin 10mg is well tolerated by young healthy subjects and may therefore be safely administered to young normotensive patients affected by distal ureteral stones and prostatitis."5.12Alfuzosin (10 mg) does not affect blood pressure in young healthy men. ( Bartoletti, R; Cai, T; Carini, M; Gavazzi, A; Geppetti, P; Giubilei, G; Gontero, P; Mondaini, N; Ungar, A, 2006)
"The aim of this study is to evaluate the efficacy of alfuzosin with methylprednisolone on expulsion and pain control of lower ureteral stones <10 mm in size."3.78Effects of alfuzosin with methylprednisolone for spontaneous expulsion and pain control of lower ureteral stone. ( Hwang, EC; Hwang, IS; Jung, SI; Kang, TW; Kim, MK; Kim, SO; Kwon, DD; Lu, JW; Park, K; Ryu, SB; Yu, HS, 2012)
"Alfuzosin therapy was tolerable with only minor adverse effects (headache, dizziness, mild postural hypotension, and rhinitis)."2.80Alfuzosin treatment improves the rate and time for stone expulsion in patients with distal uretral stones: a prospective randomized controlled study. ( El Said, NO; El Wakeel, L; Kamal, KM; Morad, Ael R, 2015)
"Alfuzosin is a safe and effective agent for the expulsive therapy of ureteral stones smaller than 10 mm in size."2.52Efficacy and Safety of Alfuzosin as Medical Expulsive Therapy for Ureteral Stones: A Systematic Review and Meta-Analysis. ( Chen, K; Kang, R; Li, J; Liu, C; Wan, SP; Wu, W; Zeng, G, 2015)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's7 (53.85)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Oestreich, MC1
Vernooij, RW1
Sathianathen, NJ1
Hwang, EC2
Kuntz, GM1
Koziarz, A1
Scales, CD1
Dahm, P1
Sentürk, AB1
Aydin, C1
Ekici, M1
Yaytokgil, M1
Akkoc, A1
Baykam, MM1
Çelik, S1
Akdeniz, F1
Afsar Yildirim, M1
Bozkurt, O1
Gursoy Bulut, M1
Hacihasanoglu, ML1
Demir, O1
El Said, NO1
El Wakeel, L1
Kamal, KM1
Morad, Ael R1
Liu, S1
Yu, Y1
Gao, Y1
Yang, X1
Pang, Z1
Liu, C1
Zeng, G1
Kang, R1
Wu, W1
Li, J1
Chen, K1
Wan, SP1
Agrawal, M1
Gupta, M1
Gupta, A1
Agrawal, A1
Sarkari, A1
Lavania, P1
García Morúa, A1
Gutiérrez García, JD1
Martínez Montelongo, R1
Gómez Guerra, LS1
Chau, LH1
Tai, DC1
Fung, BT1
Li, JC1
Fan, CW1
Li, MK1
Hwang, IS1
Yu, HS1
Kim, SO1
Jung, SI1
Kang, TW1
Kwon, DD1
Park, K1
Ryu, SB1
Kim, MK1
Lu, JW1
Deliveliotis, C1
Chrisofos, M1
Gougousis, E1
Papatsoris, A1
Dellis, A1
Varkarakis, IM1
Mondaini, N1
Giubilei, G1
Ungar, A1
Gontero, P1
Cai, T1
Gavazzi, A1
Bartoletti, R1
Geppetti, P1
Carini, M1
Pedro, RN1
Hinck, B1
Hendlin, K1
Feia, K1
Canales, BK1
Monga, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Silodosin vs. Tamsulosin on Spontaneous Passage of Acutely Obstructing Ureteral Calculi in Medical Expulsive Therapy[NCT02369744]Phase 41 participants (Actual)Interventional2013-03-31Terminated (stopped due to due to lack of suitable patient population)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for alfuzosin and Ureteral Calculi

ArticleYear
Alpha-blockers after shock wave lithotripsy for renal or ureteral stones in adults.
    The Cochrane database of systematic reviews, 2020, 11-12, Volume: 11

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2020
Efficacy and Safety of Alfuzosin as Medical Expulsive Therapy for Ureteral Stones: A Systematic Review and Meta-Analysis.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Humans; Quinazolines; Sulfonamides; Tamsulosin; Ureter; Ureteral Calculi; Urological Agents

2015

Trials

7 trials available for alfuzosin and Ureteral Calculi

ArticleYear
Alfuzosin treatment improves the rate and time for stone expulsion in patients with distal uretral stones: a prospective randomized controlled study.
    Pharmacotherapy, 2015, Volume: 35, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Female; Humans; Male; Middle Aged; Pain; Prosp

2015
Decreased urinary glycosaminoglycan excretion following alfuzosin treatment on ureteral stent-related symptoms: a prospective, randomized, placebo-controlled study.
    Urolithiasis, 2016, Volume: 44, Issue:2

    Topics: Adult; Double-Blind Method; Female; Glycosaminoglycans; Hematuria; Humans; Lower Urinary Tract Sympt

2016
Prospective randomized trial comparing efficacy of alfuzosin and tamsulosin in management of lower ureteral stones.
    Urology, 2009, Volume: 73, Issue:4

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Female; Humans; Male; Middle Aged; Prospective Stud

2009
Medical expulsive therapy using alfuzosin for patient presenting with ureteral stone less than 10mm: a prospective randomized controlled trial.
    International journal of urology : official journal of the Japanese Urological Association, 2011, Volume: 18, Issue:7

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents,

2011
Is there a role for alpha1-blockers in treating double-J stent-related symptoms?
    Urology, 2006, Volume: 67, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Female; Humans; Hydronephrosis; Male; Middle Aged; Postop

2006
Alfuzosin (10 mg) does not affect blood pressure in young healthy men.
    European urology, 2006, Volume: 50, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adult; Blood Pressure; Cross-Over Studies; Dose-Response Relationship,

2006
Alfuzosin stone expulsion therapy for distal ureteral calculi: a double-blind, placebo controlled study.
    The Journal of urology, 2008, Volume: 179, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adult; Double-Blind Method; Female; Humans; Male; Quinazolines; Ureter

2008

Other Studies

4 other studies available for alfuzosin and Ureteral Calculi

ArticleYear
Comparison of three most frequently used alpha blocker agents in medical expulsive therapy for distal ureteral calculi, result of a retrospective observational study.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2018, Mar-31, Volume: 90, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Analgesics; Drug Combinations; Drug Utilizatio

2018
Tadalafil versus alpha blockers (alfuzosin, doxazosin, tamsulosin and silodosin) as medical expulsive therapy for < 10 mm distal and proximal ureteral stones.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2018, Jun-30, Volume: 90, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Doxazosin; Female; Flank Pain; Humans;

2018
[Use of alfuzosin for expulsion of stones in the distal third of ureter].
    Actas urologicas espanolas, 2009, Volume: 33, Issue:9

    Topics: Adrenergic alpha-Antagonists; Adult; Female; Humans; Male; Middle Aged; Quinazolines; Ureteral Calcu

2009
Effects of alfuzosin with methylprednisolone for spontaneous expulsion and pain control of lower ureteral stone.
    Urological research, 2012, Volume: 40, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Drug Therapy, Combination; Female;

2012