alfuzosin has been researched along with Muscle Contraction in 8 studies
alfuzosin: structure given in first source
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the mechanism of action of imatinib mesylate (Gleevec), a protein tyrosine kinase inhibitor on the human prostate with benign prostatic hyperplasia." | 7.77 | Imatinib mesylate (Gleevec) as protein-tyrosine kinase inhibitor elicits smooth muscle relaxation in isolated human prostatic tissue. ( Abdulkadir, NA; Cetinkaya, M; Demirturk, K; Gur, S; Hellstrom, WJ; Karabakan, M; Ozgur-Akdemir, A; Volkan-Oztekin, C, 2011) |
| "To determine how partial bladder outlet obstruction (PBOO) in a rat model affects erectile function, and whether an uroselective alpha1-adrenoceptor antagonist, alfuzosin (Sanofi-Aventis, Paris, France) attenuates any erectile dysfunction (ED)." | 7.74 | Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction. ( Agrawal, KC; Chandra, S; Gur, S; Hellstrom, WJ; Kadowitz, PJ; Koka, PS; Sikka, SC, 2008) |
| "To evaluate the efficacy of alfuzosin treatment on voiding and storage in patients with lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) with respect to bladder outlet obstruction and contractility." | 5.15 | The long-term effect of alfuzosin in patients with lower urinary tract symptoms suggestive of benign prostate hyperplasia: evaluation of voiding and storage function with respect to bladder outlet obstruction grade and contractility. ( Cho, JS; Choo, MS; Han, JY; Kim, JC; Lee, KS; Lee, YS; Song, K, 2011) |
| "To evaluate the mechanism of action of imatinib mesylate (Gleevec), a protein tyrosine kinase inhibitor on the human prostate with benign prostatic hyperplasia." | 3.77 | Imatinib mesylate (Gleevec) as protein-tyrosine kinase inhibitor elicits smooth muscle relaxation in isolated human prostatic tissue. ( Abdulkadir, NA; Cetinkaya, M; Demirturk, K; Gur, S; Hellstrom, WJ; Karabakan, M; Ozgur-Akdemir, A; Volkan-Oztekin, C, 2011) |
| "To determine how partial bladder outlet obstruction (PBOO) in a rat model affects erectile function, and whether an uroselective alpha1-adrenoceptor antagonist, alfuzosin (Sanofi-Aventis, Paris, France) attenuates any erectile dysfunction (ED)." | 3.74 | Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction. ( Agrawal, KC; Chandra, S; Gur, S; Hellstrom, WJ; Kadowitz, PJ; Koka, PS; Sikka, SC, 2008) |
| "(-)-Tamsulosin was a very potent, insurmountable antagonist of noradrenaline-mediated contractions of human prostate, yielding an approximate pA2 estimate of 9." | 1.29 | Evaluation of the pharmacological selectivity profile of alpha 1 adrenoceptor antagonists at prostatic alpha 1 adrenoceptors: binding, functional and in vivo studies. ( Chalmers, DH; Kenny, BA; Miller, AM; Naylor, AM; O'Connell, J; Williamson, IJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gur, S | 2 |
| Sikka, SC | 1 |
| Chandra, S | 1 |
| Koka, PS | 1 |
| Agrawal, KC | 1 |
| Kadowitz, PJ | 1 |
| Hellstrom, WJ | 2 |
| Kobayashi, S | 1 |
| Tomiyama, Y | 1 |
| Maruyama, K | 1 |
| Hoyano, Y | 1 |
| Yamazaki, Y | 1 |
| Kusama, H | 1 |
| Song, K | 1 |
| Choo, MS | 1 |
| Lee, KS | 1 |
| Han, JY | 1 |
| Lee, YS | 1 |
| Kim, JC | 1 |
| Cho, JS | 1 |
| Ozgur-Akdemir, A | 1 |
| Demirturk, K | 1 |
| Karabakan, M | 1 |
| Volkan-Oztekin, C | 1 |
| Abdulkadir, NA | 1 |
| Cetinkaya, M | 1 |
| Giuliano, F | 1 |
| Bernabe, J | 1 |
| Droupy, S | 1 |
| Alexandre, L | 1 |
| Allard, J | 1 |
| Tambaro, S | 1 |
| Ruiu, S | 1 |
| Dessi, C | 1 |
| Mongeau, R | 1 |
| Marchese, G | 1 |
| Pani, L | 1 |
| Colabufo, NA | 1 |
| Pagliarulo, V | 1 |
| Berardi, F | 1 |
| Contino, M | 1 |
| Perrone, R | 1 |
| Niso, M | 1 |
| Albo, G | 1 |
| de Rienzo, G | 1 |
| Pagliarulo, A | 1 |
| Kenny, BA | 1 |
| Miller, AM | 1 |
| Williamson, IJ | 1 |
| O'Connell, J | 1 |
| Chalmers, DH | 1 |
| Naylor, AM | 1 |
1 trial available for alfuzosin and Muscle Contraction
| Article | Year |
|---|---|
The long-term effect of alfuzosin in patients with lower urinary tract symptoms suggestive of benign prostate hyperplasia: evaluation of voiding and storage function with respect to bladder outlet obstruction grade and contractility.
Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Muscle | 2011 |
7 other studies available for alfuzosin and Muscle Contraction
| Article | Year |
|---|---|
Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction.
Topics: Adrenergic alpha-Antagonists; Animals; Blotting, Western; Erectile Dysfunction; Immunohistochemistry | 2008 |
Effects of four different alpha(1)-adrenoceptor antagonists on alpha-adrenoceptor agonist-induced contractions in isolated mouse and hamster ureters.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; An | 2009 |
Imatinib mesylate (Gleevec) as protein-tyrosine kinase inhibitor elicits smooth muscle relaxation in isolated human prostatic tissue.
Topics: Adrenergic alpha-Antagonists; Aged; Benzamides; Humans; Hyperplasia; Imatinib Mesylate; Male; Middle | 2011 |
A comparison of the effects of tamsulosin and alfuzosin on neurally evoked increases in bladder neck and seminal vesicle pressure in rats.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Ejaculation; Evoked Potentials; Male; M | 2004 |
Evaluation of tamsulosin and alfuzosin activity in the rat vas deferens: relevance to ejaculation delays.
Topics: Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Ejaculation; Electric Stimu | 2005 |
Human epididymal and prostatic tracts of vas deferens: different contraction response to noradrenaline stimulation in isolated organ bath assay.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Aged; Dose-Response Relationship, D | 2007 |
Evaluation of the pharmacological selectivity profile of alpha 1 adrenoceptor antagonists at prostatic alpha 1 adrenoceptors: binding, functional and in vivo studies.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Blood Pressure; D | 1996 |