alfuzosin has been researched along with Long QT Syndrome in 3 studies
alfuzosin: structure given in first source
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Incidents of adverse cardiac drug reactions are more common in patients with preexisting heart disease than the general population." | 1.39 | Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity. ( Bers, DM; Diecke, S; Gong, T; Knowles, JW; Lan, F; Lee, AS; Liang, P; Nguyen, PK; Robbins, RC; Sallam, K; Sanchez-Freire, V; Wang, PJ; Wang, Y; Wu, JC, 2013) |
| "Alfuzosin is a rare example of a non-antiarrhythmic drug that delays cardiac repolarization not by blocking hK(v)11." | 1.35 | Alfuzosin delays cardiac repolarization by a novel mechanism. ( Brown, AM; Chen, Y; Danthi, SJ; Eng, H; Kramer, JW; Kuryshev, YA; Lacerda, AE; Renganathan, M; Yang, T, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, P | 1 |
| Lan, F | 1 |
| Lee, AS | 1 |
| Gong, T | 1 |
| Sanchez-Freire, V | 1 |
| Wang, Y | 1 |
| Diecke, S | 1 |
| Sallam, K | 1 |
| Knowles, JW | 1 |
| Wang, PJ | 1 |
| Nguyen, PK | 1 |
| Bers, DM | 1 |
| Robbins, RC | 1 |
| Wu, JC | 1 |
| Extramiana, F | 1 |
| Maison-Blanche, P | 1 |
| Cabanis, MJ | 1 |
| Ortemann-Renon, C | 1 |
| Beaufils, P | 1 |
| Leenhardt, A | 1 |
| Lacerda, AE | 1 |
| Kuryshev, YA | 1 |
| Chen, Y | 1 |
| Renganathan, M | 1 |
| Eng, H | 1 |
| Danthi, SJ | 1 |
| Kramer, JW | 1 |
| Yang, T | 1 |
| Brown, AM | 1 |
1 trial available for alfuzosin and Long QT Syndrome
| Article | Year |
|---|---|
Clinical assessment of drug-induced QT prolongation in association with heart rate changes.
Topics: Adrenergic alpha-Antagonists; Adult; Aza Compounds; Cross-Over Studies; Double-Blind Method; Electro | 2005 |
2 other studies available for alfuzosin and Long QT Syndrome
| Article | Year |
|---|---|
Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity.
Topics: Action Potentials; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic, Familial; Cell Differentia | 2013 |
Alfuzosin delays cardiac repolarization by a novel mechanism.
Topics: Action Potentials; Animals; Cell Line; Female; Guinea Pigs; Humans; Long QT Syndrome; Male; Myocytes | 2008 |