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alfuzosin and Impotence

alfuzosin has been researched along with Impotence in 19 studies

alfuzosin: structure given in first source

Research Excerpts

ExcerptRelevanceReference
"This pilot study was undertaken to assess the efficacy and safety of the alpha(1)-blocker alfuzosin 10mg once daily (OD), the PDE-5 inhibitor sildenafil 25mg OD, and the combination of both on lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) and erectile dysfunction (ED)."9.12Combination of alfuzosin and sildenafil is superior to monotherapy in treating lower urinary tract symptoms and erectile dysfunction. ( Gonzalez, RR; Kaplan, SA; Te, AE, 2007)
"To examine the efficacy and safety of a once-daily formulation of alfuzosin in a pooled analysis of three parallel, randomized, double-blind, placebo-controlled 3-month studies of patients with lower urinary tract symptoms (LUTS) consistent with clinical benign prostatic hyperplasia."9.10Safety and efficacy of alfuzosin 10 mg once-daily in the treatment of lower urinary tract symptoms and clinical benign prostatic hyperplasia: a pooled analysis of three double-blind, placebo-controlled studies. ( Nordling, J; Roehrborn, CG; Van Kerrebroeck, P, 2003)
"To assess the effect of alfuzosin (XATRAL) 10 mg once daily on sexual function in men with moderate to severe lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH), patients with suggestive symptomatic BPH, an International Prostate Symptom Score (IPSS) >8 (range of scores, 0-35), and sexual attempts at least once per month were enrolled."7.78Impact of alfuzosin on sexual function in Taiwanese men with benign prostatic hyperplasia. ( Chang, HC; Chen, CS; Chen, WH; Chiang, PH; Chu, SH; Hwang, TI; Lee, LM; Lin, MS; Yeh, SD, 2012)
"To determine how partial bladder outlet obstruction (PBOO) in a rat model affects erectile function, and whether an uroselective alpha1-adrenoceptor antagonist, alfuzosin (Sanofi-Aventis, Paris, France) attenuates any erectile dysfunction (ED)."7.74Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction. ( Agrawal, KC; Chandra, S; Gur, S; Hellstrom, WJ; Kadowitz, PJ; Koka, PS; Sikka, SC, 2008)
"To assess the 3-year efficacy and safety of the selective alpha(1)-blocker alfuzosin at 10 mg once daily in men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) in 'real-life practice'."7.74Alfuzosin 10 mg once daily for treating benign prostatic hyperplasia: a 3-year experience in real-life practice. ( Alcaraz, A; Elhilali, M; Emberton, M; Hartung, R; Harving, N; Matzkin, H; Vallancien, G; van Moorselaar, RJ, 2008)
"This pilot study was undertaken to assess the efficacy and safety of the alpha(1)-blocker alfuzosin 10mg once daily (OD), the PDE-5 inhibitor sildenafil 25mg OD, and the combination of both on lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) and erectile dysfunction (ED)."5.12Combination of alfuzosin and sildenafil is superior to monotherapy in treating lower urinary tract symptoms and erectile dysfunction. ( Gonzalez, RR; Kaplan, SA; Te, AE, 2007)
"To examine the efficacy and safety of a once-daily formulation of alfuzosin in a pooled analysis of three parallel, randomized, double-blind, placebo-controlled 3-month studies of patients with lower urinary tract symptoms (LUTS) consistent with clinical benign prostatic hyperplasia."5.10Safety and efficacy of alfuzosin 10 mg once-daily in the treatment of lower urinary tract symptoms and clinical benign prostatic hyperplasia: a pooled analysis of three double-blind, placebo-controlled studies. ( Nordling, J; Roehrborn, CG; Van Kerrebroeck, P, 2003)
"alpha(1)-Adrenoceptor antagonists such as alfuzosin, doxazosin, tamsulosin and terazosin are first-line agents for the treatment of lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH), but are only second-line agents (doxazosin and terazosin only) for the treatment of arterial hypertension."4.83Effects of alpha(1)-adrenoceptor antagonists on male sexual function. ( de la Rosette, JJ; Michel, MC; van Dijk, MM, 2006)
"To assess the effect of alfuzosin (XATRAL) 10 mg once daily on sexual function in men with moderate to severe lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH), patients with suggestive symptomatic BPH, an International Prostate Symptom Score (IPSS) >8 (range of scores, 0-35), and sexual attempts at least once per month were enrolled."3.78Impact of alfuzosin on sexual function in Taiwanese men with benign prostatic hyperplasia. ( Chang, HC; Chen, CS; Chen, WH; Chiang, PH; Chu, SH; Hwang, TI; Lee, LM; Lin, MS; Yeh, SD, 2012)
"To determine how partial bladder outlet obstruction (PBOO) in a rat model affects erectile function, and whether an uroselective alpha1-adrenoceptor antagonist, alfuzosin (Sanofi-Aventis, Paris, France) attenuates any erectile dysfunction (ED)."3.74Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction. ( Agrawal, KC; Chandra, S; Gur, S; Hellstrom, WJ; Kadowitz, PJ; Koka, PS; Sikka, SC, 2008)
"Functional measurement of cavernosal smooth muscle relaxation in the presence of tadalafil and alfuzosin."3.74Combination of alfuzosin and tadalafil exerts in vitro an additive relaxant effect on human corpus cavernosum. ( Alexandre, L; Behr-Roussel, D; Charles Tremeaux, J; Combes, M; Giuliano, F; Gorny, D; Oger, S, 2008)
"To assess the 3-year efficacy and safety of the selective alpha(1)-blocker alfuzosin at 10 mg once daily in men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) in 'real-life practice'."3.74Alfuzosin 10 mg once daily for treating benign prostatic hyperplasia: a 3-year experience in real-life practice. ( Alcaraz, A; Elhilali, M; Emberton, M; Hartung, R; Harving, N; Matzkin, H; Vallancien, G; van Moorselaar, RJ, 2008)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.26)18.2507
2000's14 (73.68)29.6817
2010's4 (21.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Umul, M1
Altay, AB1
Bademkiran, F1
Turna, B1
Semerci, MB1
Apaydin, E1
Cikili, N1
Gur, S1
Sikka, SC1
Chandra, S1
Koka, PS1
Agrawal, KC1
Kadowitz, PJ1
Hellstrom, WJ1
Liguori, G1
Trombetta, C1
De Giorgi, G1
Pomara, G1
Maio, G1
Vecchio, D1
Ocello, G1
Ollandini, G1
Bucci, S1
Belgrano, E1
Roumeguère, T1
Zouaoui Boudjeltia, K1
Hauzeur, C1
Schulman, C1
Vanhaeverbeek, M1
Wespes, E1
Leungwattanakij, S1
Watanachote, D1
Noppakulsatit, P1
Petchpaibuol, T1
Choeypunt, N1
Tongbai, T1
Wanamkang, T1
Lojanapiwat, B1
Permpongkosol, S2
Tantiwong, A1
Pripatnanont, C1
Akarasakul, D1
Kongwiwatanakul, S1
Chotikawanich, E1
Krilad-O-Larn, S1
Ratana-O-Larn, K1
Hwang, TI1
Chu, SH1
Lin, MS1
Chen, CS1
Lee, LM1
Chang, HC1
Yeh, SD1
Chen, WH1
Chiang, PH1
Larson, TR1
Palea, S1
Barras, M1
Roehrborn, CG1
Van Kerrebroeck, P1
Nordling, J1
Michel, MC2
Seftel, A1
van Dijk, MM1
de la Rosette, JJ1
O'Leary, MP1
Kaplan, SA1
Gonzalez, RR1
Te, AE1
Sciarra, A1
Oger, S1
Behr-Roussel, D1
Gorny, D1
Charles Tremeaux, J1
Combes, M1
Alexandre, L1
Giuliano, F1
Vallancien, G1
Emberton, M1
Alcaraz, A1
Matzkin, H1
van Moorselaar, RJ1
Hartung, R1
Harving, N1
Elhilali, M1
Höfner, K1
Claes, H1
De Reijke, TM1
Folkestad, B1
Speakman, MJ1

Reviews

4 reviews available for alfuzosin and Impotence

ArticleYear
Is there a rationale for the chronic use of phosphodiesterase-5 inhibitors for lower urinary tract symptoms secondary to benign prostatic hyperplasia?
    BJU international, 2009, Volume: 104, Issue:4

    Topics: Aged; Carbolines; Erectile Dysfunction; Humans; Imidazoles; Male; Middle Aged; Phosphodiesterase Inh

2009
Current treatment options for benign prostatic hyperplasia and their impact on sexual function.
    Urology, 2003, Volume: 61, Issue:4

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Erectile Dysfunction; Finasteride; Human

2003
Effects of alpha(1)-adrenoceptor antagonists on male sexual function.
    Drugs, 2006, Volume: 66, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic Antagonists; Adult; Aged; Doxazosin; Ejaculation

2006
Treatment and pharmacologic management of BPH in the context of common comorbidities.
    The American journal of managed care, 2006, Volume: 12, Issue:5 Suppl

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Azasteroids; Cardiovascular Diseases; Co

2006

Trials

6 trials available for alfuzosin and Impotence

ArticleYear
Efficacy and safety of combined oral therapy with tadalafil and alfuzosin: an integrated approach to the management of patients with lower urinary tract symptoms and erectile dysfunction. Preliminary report.
    The journal of sexual medicine, 2009, Volume: 6, Issue:2

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Aged; Carbolines; Drug Therapy, Combination; Ere

2009
Sexuality and management of benign prostatic hyperplasia with alfuzosin: SAMBA Thailand.
    The journal of sexual medicine, 2010, Volume: 7, Issue:9

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Ejaculation; Erectile Dysfunction; Humans; Male; Midd

2010
Treatment with a uroselective α1-blocker improves voiding and sexual function: a study in Thai men with lower urinary tract symptoms.
    The journal of sexual medicine, 2011, Volume: 8, Issue:9

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Erectile Dysfunction; Humans; Male; Middle Aged; Peni

2011
Safety and efficacy of alfuzosin 10 mg once-daily in the treatment of lower urinary tract symptoms and clinical benign prostatic hyperplasia: a pooled analysis of three double-blind, placebo-controlled studies.
    BJU international, 2003, Volume: 92, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Erectile Dysfunct

2003
Combination of alfuzosin and sildenafil is superior to monotherapy in treating lower urinary tract symptoms and erectile dysfunction.
    European urology, 2007, Volume: 51, Issue:6

    Topics: Adrenergic alpha-Antagonists; Aged; Drug Therapy, Combination; Erectile Dysfunction; Humans; Male; M

2007
Tamsulosin 0.4 mg once daily: effect on sexual function in patients with lower urinary tract symptoms suggestive of benign prostatic obstruction.
    European urology, 1999, Volume: 36, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Drug Therapy, Combinati

1999

Other Studies

9 other studies available for alfuzosin and Impotence

ArticleYear
The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity.
    Turkish journal of medical sciences, 2014, Volume: 44, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Autonomic Nervous System; Blood Glucose; Body Mass In

2014
Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction.
    BJU international, 2008, Volume: 102, Issue:11

    Topics: Adrenergic alpha-Antagonists; Animals; Blotting, Western; Erectile Dysfunction; Immunohistochemistry

2008
Impact of alfuzosin on sexual function in Taiwanese men with benign prostatic hyperplasia.
    The Kaohsiung journal of medical sciences, 2012, Volume: 28, Issue:8

    Topics: Aged; Drug Administration Schedule; Erectile Dysfunction; Humans; Lower Urinary Tract Symptoms; Male

2012
Comparison of the relaxant effects of alfuzosin, phentolamine and sildenafil on rabbit isolated corpus cavernosum.
    BJU international, 2003, Volume: 91, Issue:9

    Topics: Adrenergic alpha-Antagonists; Animals; Erectile Dysfunction; Male; Muscle Relaxation; Penile Erectio

2003
Ejaculatory dysfunction and alpha-adrenoceptor antagonists.
    BJU international, 2004, Volume: 94, Issue:3

    Topics: Adrenergic alpha-Antagonists; Ejaculation; Erectile Dysfunction; Humans; Male; Quinazolines; Sulfona

2004
Alfuzosin 10 mg once daily improves sexual function in men with lower urinary tract symptoms and concomitant sexual dysfunction.
    The Journal of urology, 2005, Volume: 174, Issue:5

    Topics: Adrenergic alpha-Antagonists; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule;

2005
Lower urinary tract symptoms (LUTS) and sexual dysfunction (SD): new targets for new combination therapies?
    European urology, 2007, Volume: 51, Issue:6

    Topics: Adrenergic alpha-Antagonists; Age Factors; Aged; Drug Therapy, Combination; Enzyme Inhibitors; Erect

2007
Combination of alfuzosin and tadalafil exerts in vitro an additive relaxant effect on human corpus cavernosum.
    The journal of sexual medicine, 2008, Volume: 5, Issue:4

    Topics: Adrenergic alpha-Antagonists; Carbolines; Dose-Response Relationship, Drug; Drug Therapy, Combinatio

2008
Alfuzosin 10 mg once daily for treating benign prostatic hyperplasia: a 3-year experience in real-life practice.
    BJU international, 2008, Volume: 101, Issue:7

    Topics: Adrenergic alpha-Antagonists; Aged; Disease Progression; Erectile Dysfunction; Humans; Male; Nocturi

2008