Page last updated: 2024-10-22

alfuzosin and Cancer of Prostate

alfuzosin has been researched along with Cancer of Prostate in 7 studies

alfuzosin: structure given in first source

Research Excerpts

ExcerptRelevanceReference
"The adrenergic alpha-1 and -2 adrenoceptors in six human hypertrophied prostatic adenomas were measured in the saturation experiment using 3H-prazosin and 3H-yohimbine."3.68[Comparison of selective alpha-1 blockades for alpha-receptors in human hypertrophied prostatic adenomas]. ( Kondo, S; Morita, T, 1992)
"Treatment with prazosin (30 μM) altered the expression of several cell stress-related proteins: elevating phospho-p38α and reducing S6 kinase in both cell lines."1.43Relative cytotoxic potencies and cell death mechanisms of α1 -adrenoceptor antagonists in prostate cancer cell lines. ( Anoopkumar-Dukie, S; Chess-Williams, R; Forbes, A; McDermott, C, 2016)
" A history and several investigations were conducted to determine the etiology of this adverse event."1.32Priapism as a possible acute side effect of radical radiotherapy for prostate cancer. ( Hayter, C; Lomaga, MA, 2004)
"5."1.29Alfuzosin, a selective alpha 1-adrenoceptor antagonist in the lower urinary tract. ( Gautier, E; Hicks, PE; Langer, SZ; Lechaire, J; Lefèvre-Borg, F; Manoury, P; O'Connor, SE; Pierre, F; Pimoule, C; Schoemaker, H, 1993)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Forbes, A1
Anoopkumar-Dukie, S1
Chess-Williams, R1
McDermott, C1
Murtola, TJ1
Kujala, PM1
Tammela, TL1
Lomaga, MA1
Hayter, C1
Liu, SJ1
Xu, KX1
Wang, XF1
Hou, SK1
Wang, YC1
Magri, V1
Trinchieri, A1
Montanari, E1
Del Nero, A1
Mangiarotti, B1
Zirpoli, P1
de Eguileor, M1
Marras, E1
Ceriani, I1
Vral, A1
Perletti, G1
Lefèvre-Borg, F1
O'Connor, SE1
Schoemaker, H1
Hicks, PE1
Lechaire, J1
Gautier, E1
Pierre, F1
Pimoule, C1
Manoury, P1
Langer, SZ1
Morita, T1
Kondo, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Open-Labeled Study of Prophylactic Vs. Therapeutic Use of Uroxatrol to Determine Improvements in Urinary Morbidity Following Men Undergoing Prostate Brachytherapy[NCT00201630]Phase 3150 participants Interventional2005-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for alfuzosin and Cancer of Prostate

ArticleYear
Relative cytotoxic potencies and cell death mechanisms of α1 -adrenoceptor antagonists in prostate cancer cell lines.
    The Prostate, 2016, Volume: 76, Issue:8

    Topics: Adrenergic alpha-1 Receptor Antagonists; Antineoplastic Agents; Apoptosis; Autophagy; Cell Death; Ce

2016
High-grade prostate cancer and biochemical recurrence after radical prostatectomy among men using 5α-reductase inhibitors and alpha-blockers.
    The Prostate, 2013, Volume: 73, Issue:9

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-1 Receptor Antagonists; Azasteroids; Cohort Studies;

2013
Priapism as a possible acute side effect of radical radiotherapy for prostate cancer.
    The Canadian journal of urology, 2004, Volume: 11, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aged; Humans; Male; Priapism; Prostate; Prostatic Neoplasms; Quinazoli

2004
[The growth inhibition effect of alpha-adrenoceptor antagonists on androgen- independent prostate cancer cell line].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2004, May-22, Volume: 42, Issue:10

    Topics: Adrenergic alpha-Antagonists; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Survival; Do

2004
Reduction of PSA values by combination pharmacological therapy in patients with chronic prostatitis: implications for prostate cancer detection.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2007, Volume: 79, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Algorithms; Androgen Antagonists; Anti-Bacterial Agents;

2007
Alfuzosin, a selective alpha 1-adrenoceptor antagonist in the lower urinary tract.
    British journal of pharmacology, 1993, Volume: 109, Issue:4

    Topics: Adenofibroma; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cats; Decerebrate State;

1993
[Comparison of selective alpha-1 blockades for alpha-receptors in human hypertrophied prostatic adenomas].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1992, Volume: 83, Issue:3

    Topics: Adenoma; Adrenergic alpha-Antagonists; Aged; Humans; Male; Piperazines; Prazosin; Prostatic Hyperpla

1992