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alfuzosin and Bladder Neck Obstruction

alfuzosin has been researched along with Bladder Neck Obstruction in 21 studies

alfuzosin: structure given in first source

Research Excerpts

ExcerptRelevanceReference
"Our objective was to assess the effect of the selective alpha(1)-blocker alfuzosin on urodynamic parameters and quality of life in female patients with primary bladder neck obstruction (PBNO)."9.14Effect of alfuzosin on female primary bladder neck obstruction. ( Athanasopoulos, A; Giannitsas, K; Gyftopoulos, K; Perimenis, P, 2009)
"The objective of this double-blind, placebo-controlled urodynamic pressure/flow study was to assess the efficacy of short-term treatment with the alpha 1-blocker alfuzosin in outflow obstruction of patients with symptomatic benign prostatic hyperplasia (BPH)."9.08Effects of short-term treatment with the alpha 1-blocker alfuzosin on urodynamic pressure/flow parameters in patients with benign prostatic hyperplasia. ( Casadei, G; Colombo, R; Di Silverio, F; Giberti, C; Martorana, G; Pacifico, P; Rigatti, P; von Heland, M, 1997)
"A pooled analysis was conducted in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia to examine the relationship between the postvoid residual urine (PVR) volume and various clinical characteristics and to assess the effect of alfuzosin, a clinically uroselective alpha(1)-blocker, on PVR volume and any other associated outcome."8.81Postvoid residual urine in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: pooled analysis of eleven controlled studies with alfuzosin. ( Geffriaud-Ricouard, C; Hargreave, TB; McNeill, SA; Roehrborn, CG; Santoni, J, 2001)
"The efficacy of alfuzosin in improving lower urinary tract symptoms and relieving bladder outlet obstruction has been demonstrated in numerous short- and long-term placebo-controlled studies and large-scale open studies, involving over 16,000 patients with symptomatic benign prostatic hyperplasia (BPH)."8.80Clinical uroselectivity of alfuzosin in the treatment of benign prostatic hyperplasia. ( Kirby, RS, 1998)
"To determine how partial bladder outlet obstruction (PBOO) in a rat model affects erectile function, and whether an uroselective alpha1-adrenoceptor antagonist, alfuzosin (Sanofi-Aventis, Paris, France) attenuates any erectile dysfunction (ED)."7.74Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction. ( Agrawal, KC; Chandra, S; Gur, S; Hellstrom, WJ; Kadowitz, PJ; Koka, PS; Sikka, SC, 2008)
"A patient who presented with priapism after ingestion of alfuzosin is described."7.73Stuttering priapism after ingestion of alfuzosin. ( Ananthakrishnan, K; Fordham, MV; Manikandan, R; Qazi, HA, 2006)
"To evaluate the efficacy of alfuzosin treatment on voiding and storage in patients with lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) with respect to bladder outlet obstruction and contractility."5.15The long-term effect of alfuzosin in patients with lower urinary tract symptoms suggestive of benign prostate hyperplasia: evaluation of voiding and storage function with respect to bladder outlet obstruction grade and contractility. ( Cho, JS; Choo, MS; Han, JY; Kim, JC; Lee, KS; Lee, YS; Song, K, 2011)
"Our objective was to assess the effect of the selective alpha(1)-blocker alfuzosin on urodynamic parameters and quality of life in female patients with primary bladder neck obstruction (PBNO)."5.14Effect of alfuzosin on female primary bladder neck obstruction. ( Athanasopoulos, A; Giannitsas, K; Gyftopoulos, K; Perimenis, P, 2009)
"To assess the symptomatic outcome following transurethral prostatectomy (TURP), alpha-blockade and placebo treatment in uncomplicated benign prostatic hyperplasia (BPH), 260 patients were evaluated with the recently formulated Danish Prostatic Symptom Score (DAN-PSS-1) system: 205 were randomized to either the selective alpha-blocker alfuzosin or placebo and 55 underwent TURP."5.08Symptomatic outcome of transurethral prostatectomy, alpha-blockade and placebo in the treatment of benign prostatic hyperplasia. Evaluation of treatment with the Danish Prostatic Symptom Score (DAN-PSS-1) system. The ALFECH Study Group. ( Flyger, H; Hansen, BJ; Mensink, HJ; Meyhoff, HH; Mortensen, S, 1996)
"The objective of this double-blind, placebo-controlled urodynamic pressure/flow study was to assess the efficacy of short-term treatment with the alpha 1-blocker alfuzosin in outflow obstruction of patients with symptomatic benign prostatic hyperplasia (BPH)."5.08Effects of short-term treatment with the alpha 1-blocker alfuzosin on urodynamic pressure/flow parameters in patients with benign prostatic hyperplasia. ( Casadei, G; Colombo, R; Di Silverio, F; Giberti, C; Martorana, G; Pacifico, P; Rigatti, P; von Heland, M, 1997)
"A pooled analysis was conducted in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia to examine the relationship between the postvoid residual urine (PVR) volume and various clinical characteristics and to assess the effect of alfuzosin, a clinically uroselective alpha(1)-blocker, on PVR volume and any other associated outcome."4.81Postvoid residual urine in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: pooled analysis of eleven controlled studies with alfuzosin. ( Geffriaud-Ricouard, C; Hargreave, TB; McNeill, SA; Roehrborn, CG; Santoni, J, 2001)
"The efficacy of alfuzosin in improving lower urinary tract symptoms and relieving bladder outlet obstruction has been demonstrated in numerous short- and long-term placebo-controlled studies and large-scale open studies, involving over 16,000 patients with symptomatic benign prostatic hyperplasia (BPH)."4.80Clinical uroselectivity of alfuzosin in the treatment of benign prostatic hyperplasia. ( Kirby, RS, 1998)
"To determine how partial bladder outlet obstruction (PBOO) in a rat model affects erectile function, and whether an uroselective alpha1-adrenoceptor antagonist, alfuzosin (Sanofi-Aventis, Paris, France) attenuates any erectile dysfunction (ED)."3.74Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction. ( Agrawal, KC; Chandra, S; Gur, S; Hellstrom, WJ; Kadowitz, PJ; Koka, PS; Sikka, SC, 2008)
"A patient who presented with priapism after ingestion of alfuzosin is described."3.73Stuttering priapism after ingestion of alfuzosin. ( Ananthakrishnan, K; Fordham, MV; Manikandan, R; Qazi, HA, 2006)
"The aim of our study was to evaluate the symptomatic and urodynamic changes after 1-5 years of treatment with alfuzosin in patients with benign prostatic hyperplasia."3.72Clinical and pressure-flow changes after long-term treatment with alfuzosin SR. ( De Nunzio, C; Franco, G; Iori, F; Laurenti, C; Leonardo, C; Minardi, V, 2003)
"With tamsulosin treatment, both mesopic and scotopic PD decreased, respectively, from 3."2.73The effects of two systemic alpha1-adrenergic blockers on pupil diameter: a prospective randomized single-blind study. ( Adibelli, FM; Akova, YA; Altan-Yaycioglu, R; Gul, U; Pelit, A; Yaycioglu, O, 2007)
"alpha(1)-Blockers were effective and safe for treating young and middle-aged men with symptomatic bladder neck obstruction."2.72Obstructive primary bladder neck disease: evaluation of the efficacy and safety of alpha1-blockers. ( Artibani, W; Calpista, A; Cisternino, A; De Marco, V; Iafrate, M; Prayer Galetti, T; Zeccolini, G, 2006)
"Alfuzosina has a specific antagonist effect on the alfa-1-adrenergic post-junctional receptor posed at urethral laeve musculature, prostatic capsule and vesical trgonum."2.67[Assessment of the effects of alfuzosin on miction with dynamic echography]. ( Gentili, G; Mautone, A; Milani, M; Tucci, G, 1994)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's5 (23.81)18.2507
2000's12 (57.14)29.6817
2010's3 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Athanasopoulos, A1
Gyftopoulos, K1
Giannitsas, K1
Perimenis, P1
Gur, S1
Sikka, SC1
Chandra, S1
Koka, PS1
Agrawal, KC1
Kadowitz, PJ1
Hellstrom, WJ1
Koh, JS1
Kim, SJ1
Kim, HS1
Kim, JC2
Lee, YS2
Lee, HN1
Han, JY2
Choo, MS2
Lee, KS2
Song, K1
Cho, JS1
De Nunzio, C1
Franco, G1
Iori, F1
Leonardo, C1
Minardi, V1
Laurenti, C1
van Moorselaar, RJ1
Hartung, R1
Emberton, M1
Harving, N1
Matzkin, H1
Elhilali, M1
Alcaraz, A1
Vallancien, G1
Seftel, A1
Cisternino, A1
Zeccolini, G1
Calpista, A1
De Marco, V1
Prayer Galetti, T1
Iafrate, M1
Artibani, W1
Qazi, HA1
Ananthakrishnan, K1
Manikandan, R1
Fordham, MV1
Altan-Yaycioglu, R1
Yaycioglu, O1
Gul, U1
Pelit, A1
Adibelli, FM1
Akova, YA1
Mariappan, P1
Brown, DJ1
McNeill, AS1
Milani, M1
Mautone, A1
Tucci, G1
Gentili, G1
Hansen, BJ1
Flyger, H1
Mortensen, S1
Mensink, HJ1
Meyhoff, HH1
Martorana, G1
Giberti, C1
Di Silverio, F1
von Heland, M1
Rigatti, P1
Colombo, R1
Casadei, G1
Pacifico, P1
Kirby, RS1
Rossi, C1
Kortmann, BB1
Sonke, GS1
Floratos, DL1
Kiemeney, LA1
Wijkstra, H1
de la ROSETTE, JJ1
McNeill, SA1
Hargreave, TB1
Geffriaud-Ricouard, C1
Santoni, J1
Roehrborn, CG1
Chess-Williams, R1
Ramsay, JW1
Scott, GI1
Whitfield, HN1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Long Term Effects of Alfuzosin (Xatral XL) in LUTS/BPH Patients: Evaluation of Symptom-specific Goal Achievement According to Symptom Improvement, Bladder Outlet Obstruction Grade and Bladder Contractility[NCT00836823]Phase 4130 participants (Actual)Interventional2005-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for alfuzosin and Bladder Neck Obstruction

ArticleYear
Clinical uroselectivity of alfuzosin in the treatment of benign prostatic hyperplasia.
    European urology, 1998, Volume: 33 Suppl 2

    Topics: Adrenergic alpha-Antagonists; Blood Pressure; Delayed-Action Preparations; Humans; Hypotension, Orth

1998
Postvoid residual urine in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: pooled analysis of eleven controlled studies with alfuzosin.
    Urology, 2001, Volume: 57, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Humans; Male; Middle Aged

2001
The use of alpha-adrenoceptor antagonists in lower urinary tract disease.
    Expert opinion on pharmacotherapy, 2002, Volume: 3, Issue:2

    Topics: Adrenergic alpha-Antagonists; Humans; Hypertension; Male; Prostatic Hyperplasia; Quinazolines; Sulfo

2002

Trials

11 trials available for alfuzosin and Bladder Neck Obstruction

ArticleYear
Effect of alfuzosin on female primary bladder neck obstruction.
    International urogynecology journal and pelvic floor dysfunction, 2009, Volume: 20, Issue:2

    Topics: Adrenergic alpha-Antagonists; Female; Humans; Middle Aged; Patient Satisfaction; Prospective Studies

2009
Comparison of alpha-blocker, extracorporeal magnetic stimulation alone and in combination in the management of female bladder outlet obstruction.
    International urogynecology journal, 2011, Volume: 22, Issue:7

    Topics: Adrenergic alpha-Antagonists; Adult; Combined Modality Therapy; Female; Humans; Magnetic Field Thera

2011
Most bothersome symptom and symptom specific goal achievement in patients with benign prostatic obstruction: a prospective open label study.
    The Journal of urology, 2011, Volume: 185, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Goals; Humans; Male; Middle Aged; Prospective Studies; Pros

2011
The long-term effect of alfuzosin in patients with lower urinary tract symptoms suggestive of benign prostate hyperplasia: evaluation of voiding and storage function with respect to bladder outlet obstruction grade and contractility.
    Urology, 2011, Volume: 77, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Muscle

2011
Alfuzosin 10 mg once daily improves sexual function in men with lower urinary tract symptoms and concomitant sexual dysfunction.
    BJU international, 2005, Volume: 95, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aged; Ejaculation; Humans; Male; Pain; Penile Erection; Quality of Lif

2005
Obstructive primary bladder neck disease: evaluation of the efficacy and safety of alpha1-blockers.
    Urologia internationalis, 2006, Volume: 76, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Humans; Male; Middle Aged; Quinazolines; Sulfonamides; Tamsulos

2006
The effects of two systemic alpha1-adrenergic blockers on pupil diameter: a prospective randomized single-blind study.
    Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 375, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Humans; Intraoperative

2007
[Assessment of the effects of alfuzosin on miction with dynamic echography].
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 1994, Volume: 66, Issue:4 Suppl

    Topics: Adrenergic alpha-Antagonists; Double-Blind Method; Humans; Male; Prostatic Hyperplasia; Quinazolines

1994
Symptomatic outcome of transurethral prostatectomy, alpha-blockade and placebo in the treatment of benign prostatic hyperplasia. Evaluation of treatment with the Danish Prostatic Symptom Score (DAN-PSS-1) system. The ALFECH Study Group.
    Scandinavian journal of urology and nephrology, 1996, Volume: 30, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Follow-Up Studies; Humans; Male; Middle Aged;

1996
Effects of short-term treatment with the alpha 1-blocker alfuzosin on urodynamic pressure/flow parameters in patients with benign prostatic hyperplasia.
    European urology, 1997, Volume: 32, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Double-Blind Method; Follow-Up Studies; Human

1997
A double-blind controlled trial of a new alpha-1 blocking drug in the treatment of bladder outflow obstruction.
    British journal of urology, 1985, Volume: 57, Issue:6

    Topics: Adult; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Humans; Male; Middle Aged; Pro

1985

Other Studies

7 other studies available for alfuzosin and Bladder Neck Obstruction

ArticleYear
Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction.
    BJU international, 2008, Volume: 102, Issue:11

    Topics: Adrenergic alpha-Antagonists; Animals; Blotting, Western; Erectile Dysfunction; Immunohistochemistry

2008
Clinical and pressure-flow changes after long-term treatment with alfuzosin SR.
    Urologia internationalis, 2003, Volume: 71, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Humans; Male; Middle Aged; Prostatic Hyperplasia; Quinazo

2003
Alfuzosin 10 mg once daily improves sexual function in men with lower urinary tract symptoms and concomitant sexual dysfunction.
    The Journal of urology, 2005, Volume: 174, Issue:5

    Topics: Adrenergic alpha-Antagonists; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule;

2005
Stuttering priapism after ingestion of alfuzosin.
    Urology, 2006, Volume: 68, Issue:4

    Topics: Adrenergic alpha-Antagonists; Humans; Male; Middle Aged; Priapism; Quinazolines; Urinary Bladder Nec

2006
Intravesical prostatic protrusion is better than prostate volume in predicting the outcome of trial without catheter in white men presenting with acute urinary retention: a prospective clinical study.
    The Journal of urology, 2007, Volume: 178, Issue:2

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Endosonography; Humans; Male;

2007
[Alfuzosin in benign prostatic hyperplasia. A new principle is evaluated. Report of a study].
    Fortschritte der Medizin. Supplement : die Kongressinformation fur die Praxis, 1995, Volume: 166

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Humans; Male

1995
alpha-Blockade improves symptoms suggestive of bladder outlet obstruction but fails to relieve it.
    The Journal of urology, 2001, Volume: 165, Issue:1

    Topics: Adrenergic alpha-Antagonists; Humans; Male; Middle Aged; Prazosin; Quinazolines; Severity of Illness

2001