Page last updated: 2024-10-22

alfuzosin and Alzheimer Disease

alfuzosin has been researched along with Alzheimer Disease in 2 studies

alfuzosin: structure given in first source

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research Excerpts

ExcerptRelevanceReference
"Tamsulosin has been associated with dementia, but the results have been inconsistent."1.72Use of α1-adrenoceptor antagonists tamsulosin and alfuzosin and the risk of Alzheimer's disease. ( Hartikainen, S; Latvala, L; Murtola, TJ; Tiihonen, M; Tolppanen, AM, 2022)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Gurjar, AS1
Darekar, MN1
Yeong, KY1
Ooi, L1
Latvala, L1
Tiihonen, M1
Murtola, TJ1
Hartikainen, S1
Tolppanen, AM1

Other Studies

2 other studies available for alfuzosin and Alzheimer Disease

ArticleYear
In silico studies, synthesis and pharmacological evaluation to explore multi-targeted approach for imidazole analogues as potential cholinesterase inhibitors with neuroprotective role for Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2018, 05-01, Volume: 26, Issue:8

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors;

2018
Use of α1-adrenoceptor antagonists tamsulosin and alfuzosin and the risk of Alzheimer's disease.
    Pharmacoepidemiology and drug safety, 2022, Volume: 31, Issue:10

    Topics: Adrenergic alpha-Antagonists; Alzheimer Disease; Case-Control Studies; Humans; Male; Quinazolines; R

2022