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alfuzosin and Adenoma, Prostatic

alfuzosin has been researched along with Adenoma, Prostatic in 186 studies

alfuzosin: structure given in first source

Research Excerpts

ExcerptRelevanceReference
"To compare the effects of alfuzosin hydrochloride and tamsulosin hydrochloride on choroidal thickness (CT) and pupil diameter (PD) sizes in patients with benign prostatic hyperplasia."9.24The Effects of Systemic Alfuzosin and Tamsulosin Hydrochloride on Choroidal Thickness and Pupil Diameter Sizes in Cases with Benign Prostatic Hyperplasia. ( Dogan, M; Halat, AO; Karalar, M; Keles, I; Kutluksaman, B, 2017)
"The objective of this study was to assess the efficacy and safety of alfuzosin 10 mg monotherapy or combined antihypertensive medication on blood pressure (BP) in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH/LUTS) with or without antihypertensive medication."9.20Multicenter, prospective, comparative cohort study evaluating the efficacy and safety of alfuzosin 10 mg with regard to blood pressure in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia with or without antihypertensive med ( Chung, WS; Hyun, JS; Kim, SW; Lee, SW; Min, KS; Moon, DG; Moon, KH; Park, JK; Park, K; Ryu, JK; Yang, DY; Yang, SK; Zhang, LT, 2015)
"The aim of this study was to assess patient outcome after discontinuation of alfuzosin treatment in patients with benign prostatic hyperplasia (BPH)."9.17Evaluation of patient outcome after discontinuation of alfuzosin treatment for benign prostatic hyperplasia: a multicentre, prospective study. ( Chung, JH; Han, JH; Jo, JK; Kang, DH; Kim, TH; Lee, JW; Lee, JY; Lee, KS; Lee, SH; Lee, SW, 2013)
"The aim of this study was to compare the efficacy and safety of alfuzosin (Alf) and tamsulosin (Tam) in patients with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH)."9.15Randomized crossover comparison of tamsulosin and alfuzosin in patients with urinary disturbances caused by benign prostatic hyperplasia. ( Atahan, Ö; Budak, YU; Karadağ, E; Öner, S, 2011)
"To compare the efficacy of Alfuzosin XL 10 mg once daily for the acute management of acute urinary retention (AUR) with placebo in patients with benign prostatic hyperplasia (BPH) and to determine the predictors that impact this."9.14Alfuzosin 10 mg once daily increases the chances of successful trial without catheter after acute urinary retention secondary to benign prostate hyperplasia. ( Consigliere, D; Li, MK; Macalalag, M; Tibung, MJ; Tiong, HY, 2009)
"To evaluate the effect of alfuzosin 10 mg once daily administered for 2 years on progression events in men with lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH)."9.12Alfuzosin 10 mg once daily prevents overall clinical progression of benign prostatic hyperplasia but not acute urinary retention: results of a 2-year placebo-controlled study. ( Roehrborn, CG, 2006)
"To determine the efficacy and safety of the selective alpha(1)-blocker alfuzosin in men with lower urinary tract symptoms (LUTS) and painful ejaculation, compared with those with LUTS only, as painful ejaculation is one of the most prevalent, differentiating and bothersome symptoms in men with chronic prostatitis/chronic pelvic pain syndrome."9.12The beneficial effect of alfuzosin 10 mg once daily in 'real-life' practice on lower urinary tract symptoms (LUTS), quality of life and sexual dysfunction in men with LUTS and painful ejaculation. ( Elhilali, M; Emberton, M; Nickel, JC; Vallancien, G, 2006)
"This randomized, double-blind, placebo-controlled study was conducted to investigate whether alfuzosin 10 mg once daily improves the maximum flow rate (Q(max)) and lower urinary tract symptoms (LUTS) of benign prostatic hyperplasia (BPH) after 1 week and 1 month of treatment."9.12Rapid onset of action with alfuzosin 10 mg once daily in men with benign prostatic hyperplasia: a randomized, placebo-controlled trial. ( Resnick, MI; Roehrborn, CG, 2007)
"This pilot study was undertaken to assess the efficacy and safety of the alpha(1)-blocker alfuzosin 10mg once daily (OD), the PDE-5 inhibitor sildenafil 25mg OD, and the combination of both on lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) and erectile dysfunction (ED)."9.12Combination of alfuzosin and sildenafil is superior to monotherapy in treating lower urinary tract symptoms and erectile dysfunction. ( Gonzalez, RR; Kaplan, SA; Te, AE, 2007)
"To study the impact of alfuzosin 10 mg once daily (OD) on the outcome of a trial without catheter (TWOC) after a first episode of acute urinary retention (AUR) related to benign prostatic hyperplasia (BPH) and the subsequent management of BPH in these patients."9.11Alfuzosin 10 mg once daily in the management of acute urinary retention: results of a double-blind placebo-controlled study. ( Hargreave, TB; McNeill, SA; Roehrborn, CG, 2005)
"A new patented prolonged release formulation of the alpha1-adrenoceptor antagonist alfuzosin has been developed for once-daily (OD) administration in benign prostatic hyperplasia (BPH)."9.10Alfuzosin, an alpha1-adrenoceptor antagonist for the treatment of benign prostatic hyperplasia: once daily versus 3 times daily dosing in healthy subjects. ( Ahtoy, P; Chrétien, P; Delfolie, A; Dupain, T; Rauch, C; Rouchouse, A, 2002)
"The blood and prostatic concentrations of alfuzosin were determined in patients with benign prostatic hyperplasia (BPH)."9.10Prostatic tissual distribution of alfuzosin in patients with benign prostatic hyperplasia following repeated oral administration. ( Bressolle, F; Costa, P; Delmas, V; Mottet, N; Robert, M, 2003)
"To examine the efficacy and safety of a once-daily formulation of alfuzosin in a pooled analysis of three parallel, randomized, double-blind, placebo-controlled 3-month studies of patients with lower urinary tract symptoms (LUTS) consistent with clinical benign prostatic hyperplasia."9.10Safety and efficacy of alfuzosin 10 mg once-daily in the treatment of lower urinary tract symptoms and clinical benign prostatic hyperplasia: a pooled analysis of three double-blind, placebo-controlled studies. ( Nordling, J; Roehrborn, CG; Van Kerrebroeck, P, 2003)
"Together, our findings suggest that alfuzosin OD exhibits a urodynamically measurable effect on bladder outlet obstruction due to benign prostatic hyperplasia in men with lower urinary tract symptoms within hours of the first administration."9.10First dose efficacy of alfuzosin once daily in men with symptomatic benign prostatic hyperplasia. ( Forrest, J; Gittelman, M; Jacobs, S; Kim, D; Marks, LS; Roehrborn, CG, 2003)
") prolonged-release formulation of the clinically uroselective alpha1-blocker, alfuzosin, in patients with symptomatic benign prostatic hyperplasia (BPH)."9.10Long-term safety and efficacy of a once-daily formulation of alfuzosin 10 mg in patients with symptomatic benign prostatic hyperplasia: open-label extension study. ( Jardin, A; Laval, KU; van Cangh, P; van Kerrebroec, P, 2002)
"To establish whether the administration of sustained-release (SR) alfuzosin improves the outcome of a trial without catheter (TWOC) after an episode of acute urinary retention."9.09Sustained-release alfuzosin and trial without catheter after acute urinary retention: a prospective, placebo-controlled. ( Daruwala, PD; Hargreave, TB; McNeill, SA; Mitchell, ID; Shearer, MG, 1999)
"As we have previously published 4 articles reporting the treatment of 7,093 clinical benign prostatic hyperplasia (BPH) patients treated with alfuzosin in a 3-month open-labelled study which was subsequently extended to 12, 24, and 36 months, the objective of this article is to provide additional data on dropouts, acute urinary retention (AUR), progression to surgery, and safety under the natural conditions of general practice, paying special attention to the predictive factors."9.09History of 7,093 patients with lower urinary tract symptoms related to benign prostatic hyperplasia treated with alfuzosin in general practice up to 3 years. ( Comet, D; Grange, JC; Lukacs, B; McCarthy, C, 2000)
"To assess the efficacy and safety of a new prolonged release formulation of the uroselective alpha(1)-blocker alfuzosin for a once-daily dosing regimen in patients with lower urinary tract symptoms (LUTS) suggestive of symptomatic benign prostatic hyperplasia (BPH)."9.09Efficacy and safety of a new prolonged release formulation of alfuzosin 10 mg once daily versus alfuzosin 2.5 mg thrice daily and placebo in patients with symptomatic benign prostatic hyperplasia. ALFORTI Study Group. ( Jardin, A; Laval, KU; van Cangh, P; van Kerrebroeck, P, 2000)
"This general practitioner-run study assess the security as well as the efficacy and impact on health-related quality of life of a sustained-release (SR) form of alfuzosin in Spanish patients suffering from lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH)."9.09Safety and efficacy of sustained-release alfuzosin on lower urinary tract symptoms suggestive of benign prostatic hyperplasia in 3,095 Spanish patients evaluated during general practice. ( Alfaro, V; Badiella, L; Fernández-Hernando, N; Guil, M; Sánchez-Chapado, M, 2000)
"To assess the effect of the age of patients with benign prostatic hyperplasia (BPH) on the clinical uroselectivity of alfuzosin during general medical practice."9.09The clinical uroselectivity of alfuzosin is not significantly affected by the age of patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia. ( Alfaro, V; Badiella, LI; Fernández-Hernando, N; Guil, M; Sánchez-Chapado, M, 2000)
"To assess the efficacy and safety, and determine the optimal dosage, of a once-daily (OD) formulation of the clinically uroselective alpha(1)-blocker, alfuzosin, in patients with lower urinary tract symptoms and symptomatic benign prostatic hyperplasia."9.09Efficacy and safety of once-daily alfuzosin in the treatment of lower urinary tract symptoms and clinical benign prostatic hyperplasia: a randomized, placebo-controlled trial. ( Roehrborn, CG, 2001)
"To investigate in men with benign prostatic hyperplasia (BPH) treated in the general practitioner setting (1) the magnitude and durability of symptom score improvement with alfuzosin; (2) the effect on patients perceived health-related quality of life (HRQL) and sexuality, (3) adverse outcomes and treatment failure; and (4) progression to acute urinary retention and prostate surgery."9.08Prospective study of men with clinical benign prostatic hyperplasia treated with alfuzosin by general practitioners: 1-year results. ( Jardin, A; Leplège, A; Lukacs, B; Thibault, P, 1996)
"To assess the efficacy and safety of a sustained-release (SR) formulation of alfuzosin, a selective alpha(1)-blocker, in patients with symptomatic benign prostatic hyperplasia (BPH)."9.08Efficacy and safety of sustained-release alfuzosin 5 mg in patients with benign prostatic hyperplasia. ALGEBI Study Group. ( Buzelin, JM; Delauche-Cavallier, MC; Geffriaud-Ricouard, C; Roth, S, 1997)
"The objective of this double-blind, placebo-controlled urodynamic pressure/flow study was to assess the efficacy of short-term treatment with the alpha 1-blocker alfuzosin in outflow obstruction of patients with symptomatic benign prostatic hyperplasia (BPH)."9.08Effects of short-term treatment with the alpha 1-blocker alfuzosin on urodynamic pressure/flow parameters in patients with benign prostatic hyperplasia. ( Casadei, G; Colombo, R; Di Silverio, F; Giberti, C; Martorana, G; Pacifico, P; Rigatti, P; von Heland, M, 1997)
"To compare the efficacy and tolerability of the alpha 1 A-subtype selective drug tamsulosin with the nonsubtype-selective agent alfuzosin in the treatment of patients with lower urinary tract symptoms (LUTS) suggestive of bladder outlet obstruction (BOO), often termed symptomatic benign prostatic hyperplasia (BPH)."9.08Comparison of tamsulosin with alfuzosin in the treatment of patients with lower urinary tract symptoms suggestive of bladder outlet obstruction (symptomatic benign prostatic hyperplasia). The European Tamsulosin Study Group. ( Buzelin, JM; Fonteyne, E; Khan, A; Kontturi, M; Witjes, WP, 1997)
"Alfuzosin, a selective alpha 1-adrenoceptor antagonist which is effective in the symptomatic treatment of benign prostatic hyperplasia (BPH), was compared with prazosin, another drug commonly used for the same purpose."9.07Alpha-blocking treatment with alfuzosin in symptomatic benign prostatic hyperplasia: comparative study with prazosin. The PRAZALF Group. ( Blondin, P; Buzelin, JM; Hebert, M, 1993)
"In order to assess the efficacy and safety of alfuzosin, a selective alpha-1 receptor antagonist, 205 patients with Benign Prostatic Hyperplasia (BPH) were randomly assigned in a double-blind, placebo-controlled manner, to receive either alfuzosin 2."9.07Alfuzosin in the treatment of benign prostatic hyperplasia: effects on symptom scores, urinary flow rates and residual volume. A multicentre, double-blind, placebo-controlled trial. ALFECH Study Group. ( Hansen, BJ; Mensink, HJ; Meyhoff, HH; Nordling, J; Walter, S, 1994)
"To address the long-term results of alfuzosin, an alpha 1-antagonist, in patients with benign prostatic hyperplasia (BPH)."9.07Long-term treatment of benign prostatic hyperplasia with alfuzosin: a 24-30 month survey. BPHALF Group. ( Attali, P; Bensadoun, H; Delauche-Cavallier, MC; Jardin, A; Stalla-Bourdillon, A, 1994)
"The effects of alfuzosin, a potent alpha 1-blocker, were assessed in patients with benign prostatic hyperplasia, in a double-blind, multicenter, placebo-controlled, cross-over study."9.07Belgian multicenter clinical study of alfuzosin, a selective alpha 1-blocker, in the treatment of benign prostatic hyperplasia. The Alfuzosin Belgian Group. ( De Sy, W; Santoni, JP; Schulman, CC; Tomas, M; Vandendris, M, 1994)
"In order to assess the efficacy and safety of alfuzosin, an alpha-1 blocker, in symptomatic patients with benign prostatic hyperplasia (BPH), 131 patients who had completed a 6-month placebo-controlled trial conducted on parallel groups entered a 12-month open study; 122 patients were treated with alfuzosin for 12 months and 56 patients for 18 months."9.07Long-term treatment of benign prostatic hyperplasia with alfuzosin: a 12-18 month assessment. BPHALF Group. ( Attali, P; Bensadoun, H; Delauche-Cavallier, MC; Jardin, A, 1993)
" Search terms included benign prostatic hyperplasia, alfuzosin, treatment, alpha(1)-adrenergic receptor blocker, long-term, followup, lower urinary tract symptoms, complications or adverse events, sexual, retention and cardiovascular."8.83Alfuzosin for symptomatic benign prostatic hyperplasia: long-term experience. ( McVary, KT, 2006)
"The chemistry, pharmacology, pharmacokinetics, clinical efficacy, and adverse effects of alfuzosin hydrochloride in the treatment of benign prostatic hyperplasia (BPH) are discussed."8.82Alfuzosin hydrochloride for the treatment of benign prostatic hyperplasia. ( Lee, M, 2003)
"Extended-release (ER) alfuzosin hydrochloride is the most recently approved alpha-adrenergic receptor antagonist (AARA) for the management of symptomatic benign prostatic hyperplasia (BPH)."8.82Extended-release alfuzosin hydrochloride: a new alpha-adrenergic receptor antagonist for symptomatic benign prostatic hyperplasia. ( Guay, DR, 2004)
"To evaluate the efficacy and adverse effects of alfuzosin for the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH)."8.82Alfuzosin for treatment of lower urinary tract symptoms compatible with benign prostatic hyperplasia: a systematic review of efficacy and adverse effects. ( MacDonald, R; Wilt, TJ, 2005)
"A pooled analysis was conducted in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia to examine the relationship between the postvoid residual urine (PVR) volume and various clinical characteristics and to assess the effect of alfuzosin, a clinically uroselective alpha(1)-blocker, on PVR volume and any other associated outcome."8.81Postvoid residual urine in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: pooled analysis of eleven controlled studies with alfuzosin. ( Geffriaud-Ricouard, C; Hargreave, TB; McNeill, SA; Roehrborn, CG; Santoni, J, 2001)
"The efficacy of alfuzosin in improving lower urinary tract symptoms and relieving bladder outlet obstruction has been demonstrated in numerous short- and long-term placebo-controlled studies and large-scale open studies, involving over 16,000 patients with symptomatic benign prostatic hyperplasia (BPH)."8.80Clinical uroselectivity of alfuzosin in the treatment of benign prostatic hyperplasia. ( Kirby, RS, 1998)
"To study the efficiency of using alfuzosin 10 mg (Alfuprost MR, SUN Pharma) in routine clinical practice in order to predict its feasibility for treating acute urinary retention."7.96[The use of alfuzosin in the treatment of patients with acute urinary retention]. ( Ergakov, DV; Martov, AG, 2020)
"To assess the effect of alfuzosin (XATRAL) 10 mg once daily on sexual function in men with moderate to severe lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH), patients with suggestive symptomatic BPH, an International Prostate Symptom Score (IPSS) >8 (range of scores, 0-35), and sexual attempts at least once per month were enrolled."7.78Impact of alfuzosin on sexual function in Taiwanese men with benign prostatic hyperplasia. ( Chang, HC; Chen, CS; Chen, WH; Chiang, PH; Chu, SH; Hwang, TI; Lee, LM; Lin, MS; Yeh, SD, 2012)
"We report on 1 case of alfuzosin induced thrombocytopenia after treatment for benign prostatic hyperplasia."7.76Alfuzosin induced thrombocytopenia after treatment for benign prostatic hyperplasia. ( Güner, E; Güner, S; Mutlu, B; Taşçi, AI, 2010)
"Assess safety and efficacy of 10-mg prolonged-release alfuzosin (Xatral XL) in benign prostatic hyperplasia (BPH) patients with lower urinary tract symptoms (LUTS)."7.75Safety and efficacy of a prolonged-release formulation of alfuzosin 10 mg once daily in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia. ( Chodchoy, V; Kongkanand, A; Lojanapiwat, B; Pumpaisanchai, S; Ratana-Olarn, K; Sae-Tang, P; Taweemonkongsap, T, 2009)
"To compare the incidence of intraoperative floppy-iris syndrome (IFIS) in men exposed to tamsulosin and men exposed to alfuzosin and evaluate the effect of IFIS on the complication rate of cataract surgery."7.74Intraoperative floppy-iris syndrome associated with alpha1-adrenoreceptors: comparison of tamsulosin and alfuzosin. ( Blouin, J; Blouin, MC; Dragomir, A; Lapointe, A; Perreault, S, 2007)
"The construction and characterization of potentiometric membrane electrodes are described for the quantification of alfuzosin, a drug used in a mono- and combined therapy of benign prostatic hyperplasia (BPH)."7.74Potentiometric sensors enabling fast screening of the benign prostatic hyperplasia drug alfuzosin in pharmaceuticals, urine and serum. ( Gupta, B; Gupta, VK; Singh, AK, 2007)
"To assess the 3-year efficacy and safety of the selective alpha(1)-blocker alfuzosin at 10 mg once daily in men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) in 'real-life practice'."7.74Alfuzosin 10 mg once daily for treating benign prostatic hyperplasia: a 3-year experience in real-life practice. ( Alcaraz, A; Elhilali, M; Emberton, M; Hartung, R; Harving, N; Matzkin, H; Vallancien, G; van Moorselaar, RJ, 2008)
"To calculate the economic consequences of using alfuzosin 10 mg once daily for managing acute urinary retention (AUR) related to benign prostatic hyperplasia (BPH)."7.73The economic impact of using alfuzosin 10 mg once daily in the management of acute urinary retention in the UK: a 6-month analysis. ( Annemans, L; Cleemput, I; Hargreave, T; Lamotte, M; McNeill, A, 2005)
"We analyzed the influence of treatment response on the risk of acute urinary retention and benign prostatic hyperplasia related surgery in 5,792 men complaining of lower urinary tract symptoms who were treated for 6 months with the selective alpha1-blocker alfuzosin at 10 mg once daily."7.73Response to daily 10 mg alfuzosin predicts acute urinary retention and benign prostatic hyperplasia related surgery in men with lower urinary tract symptoms. ( Alcaraz, A; Elhilali, M; Emberton, M; Lukacs, B; Matzkin, H; Vallancien, G, 2006)
"40 patients with benign prostatic hyperplasia (BPH) were treated with the alpha-blocker alfuzosin which was administered per os twice a day in a dose 5 mg."7.69[The treatment of patients with benign prostatic hyperplasia using the selective alpha-blocker alfuzosin]. ( Matushevskiĭ, IA; Mazo, EB; Nikitin, IuIu, 1997)
"Treatment with alfuzosin 10 mg significantly improved urinary symptoms and Qmax compared with placebo and was well tolerated."6.71Efficacy and safety of two doses (10 and 15 mg) of alfuzosin or tamsulosin (0.4 mg) once daily for treating symptomatic benign prostatic hyperplasia. ( Nordling, J, 2005)
"Alfuzosin was well tolerated: the qualitative and quantitative distribution of adverse effects was identical to that previously observed in placebo-controlled trials (vertigo-dizziness: 2."6.69[Prospective follow-up of 3,228 patients suffering from clinical benign prostatic hyperplasia (BPH) treated for 3 years wi alfuzosin in general practice. BPH Group in General Practice]. ( Comet, D; Grange, JC; Lukacs, B; Mc Carthy, C, 1999)
"Silodosin is a novel, more selective alpha-blocker, which is specific to the lower urinary tract and may have fewer side effects than other alpha-blockers."6.55Silodosin for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia. ( Dahm, P; Jung, JH; Kim, J; Kim, MH; MacDonald, R; Reddy, B, 2017)
"Alfuzosin is a uroselective alpha(1)-blocker that relaxes the smooth muscle of the bladder neck and prostate gland to alleviate BPH symptoms."6.43Efficacy and safety of alfuzosin 10 mg once daily in the treatment of symptomatic benign prostatic hyperplasia. ( Kuritzky, L; Rosenberg, MT; Sadovsky, R, 2006)
" No dosage titration is required."6.41Alfuzosin: a review of the therapeutic use of the prolonged-release formulation given once daily in the management of benign prostatic hyperplasia. ( McKeage, K; Plosker, GL, 2002)
" A limited range of clinical studies have shown oral alfuzosin to be more effective than placebo (in studies of < or = 6 months duration), to have sustained effects on long term administration (< or = 30 months), and to be comparable with the alpha 1-adrenoceptor antagonist prazosin, in the symptomatic treatment of benign prostatic hyperplasia."6.38Alfuzosin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in benign prostatic hyperplasia. ( Fitton, A; McTavish, D; Wilde, MI, 1993)
" The follow-up included 3 visits: visit of inclusion in the program of patients with a previously prescribed drug of Alfuprost MR in a dosage of 10 mg once a day (visit "0"), visit 1 at 30 days (+/-5 days) later, and visit 2 at 90 days (+/-5 days) after inclusion in the study."5.72[The influence of alfuzosin monotherapy on the sexual function of patients with benign prostatic hyperplasia in real clinical practice (results of a Russian multicenter study)]. ( Bernikov, AN; Loran, OB; Pushkar, DY, 2022)
"Incidence of benign prostatic hyperplasia (BPH), one of the most common conditions affecting adult men, increases dramatically after the age of 50."5.42[Impact of alfuzosin 10 mg once daily on quality of life in Tunisian patients with lower urinary symptoms suggestive of benign prostatic hyperplasia]. ( Adbi, H; Ben Raies, N; Ben Rhouma, S; Binous, MY; H'sairi, M; Horchani, A; Mosbah, AT; Nouira, Y, 2015)
"A novel slow release formulation of alfuzosin should improve compliance by reducing dosing to one 10 mg tablet per day."5.33Early symptom improvement of benign prostatic hyperplasia (BPH) treated with once daily alfuzosin. ( Casey, R; Elhilali, M; Kuzmarov, I; Nickel, JC; Saad, F; Valiquette, L, 2005)
"To compare the effects of alfuzosin hydrochloride and tamsulosin hydrochloride on choroidal thickness (CT) and pupil diameter (PD) sizes in patients with benign prostatic hyperplasia."5.24The Effects of Systemic Alfuzosin and Tamsulosin Hydrochloride on Choroidal Thickness and Pupil Diameter Sizes in Cases with Benign Prostatic Hyperplasia. ( Dogan, M; Halat, AO; Karalar, M; Keles, I; Kutluksaman, B, 2017)
"The objective of this study was to assess the efficacy and safety of alfuzosin 10 mg monotherapy or combined antihypertensive medication on blood pressure (BP) in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH/LUTS) with or without antihypertensive medication."5.20Multicenter, prospective, comparative cohort study evaluating the efficacy and safety of alfuzosin 10 mg with regard to blood pressure in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia with or without antihypertensive med ( Chung, WS; Hyun, JS; Kim, SW; Lee, SW; Min, KS; Moon, DG; Moon, KH; Park, JK; Park, K; Ryu, JK; Yang, DY; Yang, SK; Zhang, LT, 2015)
"To compare the efficacy and safety of tamsulosin and alfuzosin in patients with acute urinary retention (AUR) secondary to benign prostatic hyperplasia (BPH)."5.19A comparative study on the use of tamsulosin versus alfuzosin in spontaneous micturition recovery after transurethral catheter removal in patients with benign prostatic growth. ( Carrillo-Ruiz, JD; González-Valle, JC; Guzman-Esquivel, J; Labra-Salgado, IR; Maldonado-Ávila, M; Manzanilla-García, HA; Rosas-Nava, E; Sierra-Ramírez, JA, 2014)
"To compare the efficacy and safety of single (tamsulosin) and double dose (tamsulosin + alfuzosin) alpha-blocker therapy for treating catheterized patients with acute urinary retention (AUR) due to benign prostatic hyperplasia (BPH)."5.19Is the double dose alpha-blocker treatment superior than the single dose in the management of patients suffering from acute urinary retention caused by benign prostatic hyperplasia? ( Kara, O; Yazici, M, 2014)
"The aim of this study was to assess patient outcome after discontinuation of alfuzosin treatment in patients with benign prostatic hyperplasia (BPH)."5.17Evaluation of patient outcome after discontinuation of alfuzosin treatment for benign prostatic hyperplasia: a multicentre, prospective study. ( Chung, JH; Han, JH; Jo, JK; Kang, DH; Kim, TH; Lee, JW; Lee, JY; Lee, KS; Lee, SH; Lee, SW, 2013)
" We compared the efficacy of alfuzosin 10 mg alone or in combination with sildenafil 50 mg in the treatment of LUTS due to benign prostatic hyperplasia."5.16Efficacy of alfuzosin and sildenafil combination in male patients with lower urinary tract symptoms. ( Akyüz, M; Güneş, M; Kalkan, S; Karaman, MI; Koca, O; Öztürk, Mİ, 2012)
"To evaluate the efficacy of alfuzosin treatment on voiding and storage in patients with lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) with respect to bladder outlet obstruction and contractility."5.15The long-term effect of alfuzosin in patients with lower urinary tract symptoms suggestive of benign prostate hyperplasia: evaluation of voiding and storage function with respect to bladder outlet obstruction grade and contractility. ( Cho, JS; Choo, MS; Han, JY; Kim, JC; Lee, KS; Lee, YS; Song, K, 2011)
"The aim of this study was to compare the efficacy and safety of alfuzosin (Alf) and tamsulosin (Tam) in patients with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH)."5.15Randomized crossover comparison of tamsulosin and alfuzosin in patients with urinary disturbances caused by benign prostatic hyperplasia. ( Atahan, Ö; Budak, YU; Karadağ, E; Öner, S, 2011)
"To compare the efficacy of Alfuzosin XL 10 mg once daily for the acute management of acute urinary retention (AUR) with placebo in patients with benign prostatic hyperplasia (BPH) and to determine the predictors that impact this."5.14Alfuzosin 10 mg once daily increases the chances of successful trial without catheter after acute urinary retention secondary to benign prostate hyperplasia. ( Consigliere, D; Li, MK; Macalalag, M; Tibung, MJ; Tiong, HY, 2009)
"To determine the effect of alfuzosin on sexual function by using the Male Sexual Health Questionnaire (MSHQ) in men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH)."5.14An open, non-comparative, multicentre study on the impact of alfuzosin on sexual function using the Male Sexual Health Questionnaire in patients with benign prostate hyperplasia. ( Cheon, J; Chung, BH; Chung, MK; Kim, MK; Kim, SW; Lee, JY; Lee, KS; Lee, SW; Park, JK; Park, K, 2010)
"To evaluate the effect of alfuzosin 10 mg once daily administered for 2 years on progression events in men with lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH)."5.12Alfuzosin 10 mg once daily prevents overall clinical progression of benign prostatic hyperplasia but not acute urinary retention: results of a 2-year placebo-controlled study. ( Roehrborn, CG, 2006)
"To determine the efficacy and safety of the selective alpha(1)-blocker alfuzosin in men with lower urinary tract symptoms (LUTS) and painful ejaculation, compared with those with LUTS only, as painful ejaculation is one of the most prevalent, differentiating and bothersome symptoms in men with chronic prostatitis/chronic pelvic pain syndrome."5.12The beneficial effect of alfuzosin 10 mg once daily in 'real-life' practice on lower urinary tract symptoms (LUTS), quality of life and sexual dysfunction in men with LUTS and painful ejaculation. ( Elhilali, M; Emberton, M; Nickel, JC; Vallancien, G, 2006)
"This randomized, double-blind, placebo-controlled study was conducted to investigate whether alfuzosin 10 mg once daily improves the maximum flow rate (Q(max)) and lower urinary tract symptoms (LUTS) of benign prostatic hyperplasia (BPH) after 1 week and 1 month of treatment."5.12Rapid onset of action with alfuzosin 10 mg once daily in men with benign prostatic hyperplasia: a randomized, placebo-controlled trial. ( Resnick, MI; Roehrborn, CG, 2007)
"This pilot study was undertaken to assess the efficacy and safety of the alpha(1)-blocker alfuzosin 10mg once daily (OD), the PDE-5 inhibitor sildenafil 25mg OD, and the combination of both on lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) and erectile dysfunction (ED)."5.12Combination of alfuzosin and sildenafil is superior to monotherapy in treating lower urinary tract symptoms and erectile dysfunction. ( Gonzalez, RR; Kaplan, SA; Te, AE, 2007)
"To study the impact of alfuzosin 10 mg once daily (OD) on the outcome of a trial without catheter (TWOC) after a first episode of acute urinary retention (AUR) related to benign prostatic hyperplasia (BPH) and the subsequent management of BPH in these patients."5.11Alfuzosin 10 mg once daily in the management of acute urinary retention: results of a double-blind placebo-controlled study. ( Hargreave, TB; McNeill, SA; Roehrborn, CG, 2005)
"A new patented prolonged release formulation of the alpha1-adrenoceptor antagonist alfuzosin has been developed for once-daily (OD) administration in benign prostatic hyperplasia (BPH)."5.10Alfuzosin, an alpha1-adrenoceptor antagonist for the treatment of benign prostatic hyperplasia: once daily versus 3 times daily dosing in healthy subjects. ( Ahtoy, P; Chrétien, P; Delfolie, A; Dupain, T; Rauch, C; Rouchouse, A, 2002)
"The blood and prostatic concentrations of alfuzosin were determined in patients with benign prostatic hyperplasia (BPH)."5.10Prostatic tissual distribution of alfuzosin in patients with benign prostatic hyperplasia following repeated oral administration. ( Bressolle, F; Costa, P; Delmas, V; Mottet, N; Robert, M, 2003)
"To examine the efficacy and safety of a once-daily formulation of alfuzosin in a pooled analysis of three parallel, randomized, double-blind, placebo-controlled 3-month studies of patients with lower urinary tract symptoms (LUTS) consistent with clinical benign prostatic hyperplasia."5.10Safety and efficacy of alfuzosin 10 mg once-daily in the treatment of lower urinary tract symptoms and clinical benign prostatic hyperplasia: a pooled analysis of three double-blind, placebo-controlled studies. ( Nordling, J; Roehrborn, CG; Van Kerrebroeck, P, 2003)
"Together, our findings suggest that alfuzosin OD exhibits a urodynamically measurable effect on bladder outlet obstruction due to benign prostatic hyperplasia in men with lower urinary tract symptoms within hours of the first administration."5.10First dose efficacy of alfuzosin once daily in men with symptomatic benign prostatic hyperplasia. ( Forrest, J; Gittelman, M; Jacobs, S; Kim, D; Marks, LS; Roehrborn, CG, 2003)
") prolonged-release formulation of the clinically uroselective alpha1-blocker, alfuzosin, in patients with symptomatic benign prostatic hyperplasia (BPH)."5.10Long-term safety and efficacy of a once-daily formulation of alfuzosin 10 mg in patients with symptomatic benign prostatic hyperplasia: open-label extension study. ( Jardin, A; Laval, KU; van Cangh, P; van Kerrebroec, P, 2002)
"To establish whether the administration of sustained-release (SR) alfuzosin improves the outcome of a trial without catheter (TWOC) after an episode of acute urinary retention."5.09Sustained-release alfuzosin and trial without catheter after acute urinary retention: a prospective, placebo-controlled. ( Daruwala, PD; Hargreave, TB; McNeill, SA; Mitchell, ID; Shearer, MG, 1999)
"As we have previously published 4 articles reporting the treatment of 7,093 clinical benign prostatic hyperplasia (BPH) patients treated with alfuzosin in a 3-month open-labelled study which was subsequently extended to 12, 24, and 36 months, the objective of this article is to provide additional data on dropouts, acute urinary retention (AUR), progression to surgery, and safety under the natural conditions of general practice, paying special attention to the predictive factors."5.09History of 7,093 patients with lower urinary tract symptoms related to benign prostatic hyperplasia treated with alfuzosin in general practice up to 3 years. ( Comet, D; Grange, JC; Lukacs, B; McCarthy, C, 2000)
"To assess the efficacy and safety of a new prolonged release formulation of the uroselective alpha(1)-blocker alfuzosin for a once-daily dosing regimen in patients with lower urinary tract symptoms (LUTS) suggestive of symptomatic benign prostatic hyperplasia (BPH)."5.09Efficacy and safety of a new prolonged release formulation of alfuzosin 10 mg once daily versus alfuzosin 2.5 mg thrice daily and placebo in patients with symptomatic benign prostatic hyperplasia. ALFORTI Study Group. ( Jardin, A; Laval, KU; van Cangh, P; van Kerrebroeck, P, 2000)
"This general practitioner-run study assess the security as well as the efficacy and impact on health-related quality of life of a sustained-release (SR) form of alfuzosin in Spanish patients suffering from lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH)."5.09Safety and efficacy of sustained-release alfuzosin on lower urinary tract symptoms suggestive of benign prostatic hyperplasia in 3,095 Spanish patients evaluated during general practice. ( Alfaro, V; Badiella, L; Fernández-Hernando, N; Guil, M; Sánchez-Chapado, M, 2000)
"To assess the effect of the age of patients with benign prostatic hyperplasia (BPH) on the clinical uroselectivity of alfuzosin during general medical practice."5.09The clinical uroselectivity of alfuzosin is not significantly affected by the age of patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia. ( Alfaro, V; Badiella, LI; Fernández-Hernando, N; Guil, M; Sánchez-Chapado, M, 2000)
"To assess the efficacy and safety, and determine the optimal dosage, of a once-daily (OD) formulation of the clinically uroselective alpha(1)-blocker, alfuzosin, in patients with lower urinary tract symptoms and symptomatic benign prostatic hyperplasia."5.09Efficacy and safety of once-daily alfuzosin in the treatment of lower urinary tract symptoms and clinical benign prostatic hyperplasia: a randomized, placebo-controlled trial. ( Roehrborn, CG, 2001)
"To assess the symptomatic outcome following transurethral prostatectomy (TURP), alpha-blockade and placebo treatment in uncomplicated benign prostatic hyperplasia (BPH), 260 patients were evaluated with the recently formulated Danish Prostatic Symptom Score (DAN-PSS-1) system: 205 were randomized to either the selective alpha-blocker alfuzosin or placebo and 55 underwent TURP."5.08Symptomatic outcome of transurethral prostatectomy, alpha-blockade and placebo in the treatment of benign prostatic hyperplasia. Evaluation of treatment with the Danish Prostatic Symptom Score (DAN-PSS-1) system. The ALFECH Study Group. ( Flyger, H; Hansen, BJ; Mensink, HJ; Meyhoff, HH; Mortensen, S, 1996)
"To investigate in men with benign prostatic hyperplasia (BPH) treated in the general practitioner setting (1) the magnitude and durability of symptom score improvement with alfuzosin; (2) the effect on patients perceived health-related quality of life (HRQL) and sexuality, (3) adverse outcomes and treatment failure; and (4) progression to acute urinary retention and prostate surgery."5.08Prospective study of men with clinical benign prostatic hyperplasia treated with alfuzosin by general practitioners: 1-year results. ( Jardin, A; Leplège, A; Lukacs, B; Thibault, P, 1996)
"To assess the efficacy and safety of a sustained-release (SR) formulation of alfuzosin, a selective alpha(1)-blocker, in patients with symptomatic benign prostatic hyperplasia (BPH)."5.08Efficacy and safety of sustained-release alfuzosin 5 mg in patients with benign prostatic hyperplasia. ALGEBI Study Group. ( Buzelin, JM; Delauche-Cavallier, MC; Geffriaud-Ricouard, C; Roth, S, 1997)
"Two placebo-controlled studies involving 588 patients (292 receiving SR alfuzosin 5 mg twice daily and 296 a placebo) were pooled; 51% of the patients were > or = 65 years of age and 43% had associated cardiovascular disease including hypertension and/or were receiving concomitant antihypertensive drugs."5.08Clinical uroselectivity: evidence from patients treated with slow-release alfuzosin for symptomatic benign prostatic obstruction. ( Buzelin, JM; Delauche-Cavallier, MC; Geffriaud-Ricouard, C; Roth, S; Santoni, JP, 1997)
"The objective of this double-blind, placebo-controlled urodynamic pressure/flow study was to assess the efficacy of short-term treatment with the alpha 1-blocker alfuzosin in outflow obstruction of patients with symptomatic benign prostatic hyperplasia (BPH)."5.08Effects of short-term treatment with the alpha 1-blocker alfuzosin on urodynamic pressure/flow parameters in patients with benign prostatic hyperplasia. ( Casadei, G; Colombo, R; Di Silverio, F; Giberti, C; Martorana, G; Pacifico, P; Rigatti, P; von Heland, M, 1997)
"To compare the efficacy and tolerability of the alpha 1 A-subtype selective drug tamsulosin with the nonsubtype-selective agent alfuzosin in the treatment of patients with lower urinary tract symptoms (LUTS) suggestive of bladder outlet obstruction (BOO), often termed symptomatic benign prostatic hyperplasia (BPH)."5.08Comparison of tamsulosin with alfuzosin in the treatment of patients with lower urinary tract symptoms suggestive of bladder outlet obstruction (symptomatic benign prostatic hyperplasia). The European Tamsulosin Study Group. ( Buzelin, JM; Fonteyne, E; Khan, A; Kontturi, M; Witjes, WP, 1997)
"Alfuzosin, a selective alpha 1-adrenoceptor antagonist which is effective in the symptomatic treatment of benign prostatic hyperplasia (BPH), was compared with prazosin, another drug commonly used for the same purpose."5.07Alpha-blocking treatment with alfuzosin in symptomatic benign prostatic hyperplasia: comparative study with prazosin. The PRAZALF Group. ( Blondin, P; Buzelin, JM; Hebert, M, 1993)
"In order to assess the efficacy and safety of alfuzosin, a selective alpha-1 receptor antagonist, 205 patients with Benign Prostatic Hyperplasia (BPH) were randomly assigned in a double-blind, placebo-controlled manner, to receive either alfuzosin 2."5.07Alfuzosin in the treatment of benign prostatic hyperplasia: effects on symptom scores, urinary flow rates and residual volume. A multicentre, double-blind, placebo-controlled trial. ALFECH Study Group. ( Hansen, BJ; Mensink, HJ; Meyhoff, HH; Nordling, J; Walter, S, 1994)
"To address the long-term results of alfuzosin, an alpha 1-antagonist, in patients with benign prostatic hyperplasia (BPH)."5.07Long-term treatment of benign prostatic hyperplasia with alfuzosin: a 24-30 month survey. BPHALF Group. ( Attali, P; Bensadoun, H; Delauche-Cavallier, MC; Jardin, A; Stalla-Bourdillon, A, 1994)
"The effects of alfuzosin, a potent alpha 1-blocker, were assessed in patients with benign prostatic hyperplasia, in a double-blind, multicenter, placebo-controlled, cross-over study."5.07Belgian multicenter clinical study of alfuzosin, a selective alpha 1-blocker, in the treatment of benign prostatic hyperplasia. The Alfuzosin Belgian Group. ( De Sy, W; Santoni, JP; Schulman, CC; Tomas, M; Vandendris, M, 1994)
"In order to assess the efficacy and safety of alfuzosin, an alpha-1 blocker, in symptomatic patients with benign prostatic hyperplasia (BPH), 131 patients who had completed a 6-month placebo-controlled trial conducted on parallel groups entered a 12-month open study; 122 patients were treated with alfuzosin for 12 months and 56 patients for 18 months."5.07Long-term treatment of benign prostatic hyperplasia with alfuzosin: a 12-18 month assessment. BPHALF Group. ( Attali, P; Bensadoun, H; Delauche-Cavallier, MC; Jardin, A, 1993)
" Search terms included benign prostatic hyperplasia, alfuzosin, treatment, alpha(1)-adrenergic receptor blocker, long-term, followup, lower urinary tract symptoms, complications or adverse events, sexual, retention and cardiovascular."4.83Alfuzosin for symptomatic benign prostatic hyperplasia: long-term experience. ( McVary, KT, 2006)
"alpha(1)-Adrenoceptor antagonists such as alfuzosin, doxazosin, tamsulosin and terazosin are first-line agents for the treatment of lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH), but are only second-line agents (doxazosin and terazosin only) for the treatment of arterial hypertension."4.83Effects of alpha(1)-adrenoceptor antagonists on male sexual function. ( de la Rosette, JJ; Michel, MC; van Dijk, MM, 2006)
"The chemistry, pharmacology, pharmacokinetics, clinical efficacy, and adverse effects of alfuzosin hydrochloride in the treatment of benign prostatic hyperplasia (BPH) are discussed."4.82Alfuzosin hydrochloride for the treatment of benign prostatic hyperplasia. ( Lee, M, 2003)
"Extended-release (ER) alfuzosin hydrochloride is the most recently approved alpha-adrenergic receptor antagonist (AARA) for the management of symptomatic benign prostatic hyperplasia (BPH)."4.82Extended-release alfuzosin hydrochloride: a new alpha-adrenergic receptor antagonist for symptomatic benign prostatic hyperplasia. ( Guay, DR, 2004)
"To evaluate the efficacy and adverse effects of alfuzosin for the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH)."4.82Alfuzosin for treatment of lower urinary tract symptoms compatible with benign prostatic hyperplasia: a systematic review of efficacy and adverse effects. ( MacDonald, R; Wilt, TJ, 2005)
"A pooled analysis was conducted in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia to examine the relationship between the postvoid residual urine (PVR) volume and various clinical characteristics and to assess the effect of alfuzosin, a clinically uroselective alpha(1)-blocker, on PVR volume and any other associated outcome."4.81Postvoid residual urine in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: pooled analysis of eleven controlled studies with alfuzosin. ( Geffriaud-Ricouard, C; Hargreave, TB; McNeill, SA; Roehrborn, CG; Santoni, J, 2001)
"The efficacy of alfuzosin in improving lower urinary tract symptoms and relieving bladder outlet obstruction has been demonstrated in numerous short- and long-term placebo-controlled studies and large-scale open studies, involving over 16,000 patients with symptomatic benign prostatic hyperplasia (BPH)."4.80Clinical uroselectivity of alfuzosin in the treatment of benign prostatic hyperplasia. ( Kirby, RS, 1998)
"To study the efficiency of using alfuzosin 10 mg (Alfuprost MR, SUN Pharma) in routine clinical practice in order to predict its feasibility for treating acute urinary retention."3.96[The use of alfuzosin in the treatment of patients with acute urinary retention]. ( Ergakov, DV; Martov, AG, 2020)
"Alfuzosin and tamsulosin are recently co-administrated with vardenafil to treat symptoms of benign prostatic hyperplasia and erectile dysfunction."3.91Simultaneous HPLC determination of alfuzosin, tamsulosin and vardenafil in human plasma and pharmaceutical formulations using time programmed fluorescence detection. ( Belal, F; Borg, H; Fathy, M; Walash, MI; Zayed, S, 2019)
"To assess the effect of alfuzosin (XATRAL) 10 mg once daily on sexual function in men with moderate to severe lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH), patients with suggestive symptomatic BPH, an International Prostate Symptom Score (IPSS) >8 (range of scores, 0-35), and sexual attempts at least once per month were enrolled."3.78Impact of alfuzosin on sexual function in Taiwanese men with benign prostatic hyperplasia. ( Chang, HC; Chen, CS; Chen, WH; Chiang, PH; Chu, SH; Hwang, TI; Lee, LM; Lin, MS; Yeh, SD, 2012)
"We report on 1 case of alfuzosin induced thrombocytopenia after treatment for benign prostatic hyperplasia."3.76Alfuzosin induced thrombocytopenia after treatment for benign prostatic hyperplasia. ( Güner, E; Güner, S; Mutlu, B; Taşçi, AI, 2010)
"Assess safety and efficacy of 10-mg prolonged-release alfuzosin (Xatral XL) in benign prostatic hyperplasia (BPH) patients with lower urinary tract symptoms (LUTS)."3.75Safety and efficacy of a prolonged-release formulation of alfuzosin 10 mg once daily in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia. ( Chodchoy, V; Kongkanand, A; Lojanapiwat, B; Pumpaisanchai, S; Ratana-Olarn, K; Sae-Tang, P; Taweemonkongsap, T, 2009)
"To compare the incidence of intraoperative floppy-iris syndrome (IFIS) in men exposed to tamsulosin and men exposed to alfuzosin and evaluate the effect of IFIS on the complication rate of cataract surgery."3.74Intraoperative floppy-iris syndrome associated with alpha1-adrenoreceptors: comparison of tamsulosin and alfuzosin. ( Blouin, J; Blouin, MC; Dragomir, A; Lapointe, A; Perreault, S, 2007)
"The construction and characterization of potentiometric membrane electrodes are described for the quantification of alfuzosin, a drug used in a mono- and combined therapy of benign prostatic hyperplasia (BPH)."3.74Potentiometric sensors enabling fast screening of the benign prostatic hyperplasia drug alfuzosin in pharmaceuticals, urine and serum. ( Gupta, B; Gupta, VK; Singh, AK, 2007)
"To assess the 3-year efficacy and safety of the selective alpha(1)-blocker alfuzosin at 10 mg once daily in men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) in 'real-life practice'."3.74Alfuzosin 10 mg once daily for treating benign prostatic hyperplasia: a 3-year experience in real-life practice. ( Alcaraz, A; Elhilali, M; Emberton, M; Hartung, R; Harving, N; Matzkin, H; Vallancien, G; van Moorselaar, RJ, 2008)
"To assess the predictors of acute urinary retention (AUR) and/or surgery related to benign prostatic hyperplasia (BPH) in 3514 men complaining of lower urinary tract symptoms and treated for 6 months with the selective alpha1-blocker alfuzosin at 10 mg once daily."3.73Symptom deterioration during treatment and history of AUR are the strongest predictors for AUR and BPH-related surgery in men with LUTS treated with alfuzosin 10 mg once daily. ( Alcaraz, A; Elhilali, M; Emberton, M; Hartung, R; Harving, N; Matzkin, H; Vallancien, G; van Moorselaar, J, 2005)
"To calculate the economic consequences of using alfuzosin 10 mg once daily for managing acute urinary retention (AUR) related to benign prostatic hyperplasia (BPH)."3.73The economic impact of using alfuzosin 10 mg once daily in the management of acute urinary retention in the UK: a 6-month analysis. ( Annemans, L; Cleemput, I; Hargreave, T; Lamotte, M; McNeill, A, 2005)
"We analyzed the influence of treatment response on the risk of acute urinary retention and benign prostatic hyperplasia related surgery in 5,792 men complaining of lower urinary tract symptoms who were treated for 6 months with the selective alpha1-blocker alfuzosin at 10 mg once daily."3.73Response to daily 10 mg alfuzosin predicts acute urinary retention and benign prostatic hyperplasia related surgery in men with lower urinary tract symptoms. ( Alcaraz, A; Elhilali, M; Emberton, M; Lukacs, B; Matzkin, H; Vallancien, G, 2006)
"The aim of our study was to evaluate the symptomatic and urodynamic changes after 1-5 years of treatment with alfuzosin in patients with benign prostatic hyperplasia."3.72Clinical and pressure-flow changes after long-term treatment with alfuzosin SR. ( De Nunzio, C; Franco, G; Iori, F; Laurenti, C; Leonardo, C; Minardi, V, 2003)
"To determine the effectiveness of alfuzosin on symptom reduction, patients' perceived health-related quality of life (HRQL) improvement, adverse outcomes, treatment failure, and progression to acute urinary retention and prostate surgery in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH) in a 1-year prospective, open-labeled study."3.70One-year follow-up of 2829 patients with moderate to severe lower urinary tract symptoms treated with alfuzosin in general practice according to IPSS and a health-related quality-of-life questionnaire. BPM Group in General Practice. ( Comet, D; Grange, JC; Lukacs, B, 2000)
"40 patients with benign prostatic hyperplasia (BPH) were treated with the alpha-blocker alfuzosin which was administered per os twice a day in a dose 5 mg."3.69[The treatment of patients with benign prostatic hyperplasia using the selective alpha-blocker alfuzosin]. ( Matushevskiĭ, IA; Mazo, EB; Nikitin, IuIu, 1997)
"The adrenergic alpha-1 and -2 adrenoceptors in six human hypertrophied prostatic adenomas were measured in the saturation experiment using 3H-prazosin and 3H-yohimbine."3.68[Comparison of selective alpha-1 blockades for alpha-receptors in human hypertrophied prostatic adenomas]. ( Kondo, S; Morita, T, 1992)
"Patients with symptomatic benign prostatic hyperplasia and cataracts requiring a uroselective α1-antagonist may consider trying alfuzosin first."2.79Prospective masked comparison of intraoperative floppy iris syndrome severity with tamsulosin versus alfuzosin. ( Campbell, JR; Chang, DF; Colin, J; Schweitzer, C, 2014)
"With tamsulosin treatment, both mesopic and scotopic PD decreased, respectively, from 3."2.73The effects of two systemic alpha1-adrenergic blockers on pupil diameter: a prospective randomized single-blind study. ( Adibelli, FM; Akova, YA; Altan-Yaycioglu, R; Gul, U; Pelit, A; Yaycioglu, O, 2007)
"The aetiology of AUR was benign prostatic hyperplasia (BPH) in 29 patients and constipation in the remaining 2 patients."2.72A prospective pilot study to validate the management protocol for patients presenting with acute urinary retention: a community-based, nonhospitalised protocol. ( Byrne, DJ; Goodman, CM; Gopi, SS; Robertson, A, 2006)
"Doxazosin and alfuzosin were both well tolerated, with most all-cause adverse events reported as mild or moderate."2.71Comparative efficacy of two alpha-adrenoreceptor antagonists, doxazosin and alfuzosin, in patients with lower urinary tract symptoms from benign prostatic enlargement. ( de Reijke, TM; Klarskov, P, 2004)
"Treatment with alfuzosin 10 mg significantly improved urinary symptoms and Qmax compared with placebo and was well tolerated."2.71Efficacy and safety of two doses (10 and 15 mg) of alfuzosin or tamsulosin (0.4 mg) once daily for treating symptomatic benign prostatic hyperplasia. ( Nordling, J, 2005)
"Alfuzosin 10 mg OD is an effective treatment for symptomatic BPH for at least 12 months, with a better cardiovascular safety profile than the immediate release formulation."2.70The efficacy and safety of a new once-a-day formulation of an alpha-blocker. ( Van Kerrebroeck, PE, 2001)
"Alfuzosin was well tolerated: the quantitative and qualitative distribution of adverse events (AEs) was similar to that previously observed in placebo-controlled studies."2.69Clinical uroselectivity: a 3-year follow-up in general practice. BPH Group in General Practice. ( Comet, D; Grange, JC; Lukacs, B; McCarthy, C, 1998)
" To date, the role of varying dosing regimens in responding patients has not been well studied."2.69Intermittent alpha-blocker therapy in the treatment of men with lower urinary tract symptoms. ( Cologna, A; Kaplan, SA; Kohn, IJ; Martins, AC; Reis, RB; Suaid, HJ; Te, AE, 1998)
"Alfuzosin was well tolerated: the qualitative and quantitative distribution of adverse effects was identical to that previously observed in placebo-controlled trials (vertigo-dizziness: 2."2.69[Prospective follow-up of 3,228 patients suffering from clinical benign prostatic hyperplasia (BPH) treated for 3 years wi alfuzosin in general practice. BPH Group in General Practice]. ( Comet, D; Grange, JC; Lukacs, B; Mc Carthy, C, 1999)
"01)."2.69Safety, efficacy and impact on Patients' quality of life of a long-term treatment with the alpha(1)-blocker alfuzosin in symptomatic patients with BPH. The Italian Alfuzosin Co-Operative Group. ( , 2000)
"Alfuzosin was prescribed at the recommended dose of 2."2.68Safety profile of 3 months' therapy with alfuzosin in 13,389 patients suffering from benign prostatic hypertrophy. ( Blondin, P; Du Boys, B; Grippon, P; Lassale, C; Lukacs, B; MacCarthy, C, 1996)
"Alfuzosina has a specific antagonist effect on the alfa-1-adrenergic post-junctional receptor posed at urethral laeve musculature, prostatic capsule and vesical trgonum."2.67[Assessment of the effects of alfuzosin on miction with dynamic echography]. ( Gentili, G; Mautone, A; Milani, M; Tucci, G, 1994)
"Alfuzosin was demonstrated to be effective with respect to out-flow obstructive symptoms (quality of the stream, hesitancy, sensation of incomplete emptying of the bladder) and other functional symptoms (diurnal frequency and nocturia)."2.66[Efficacy of an alpha-blocker, alfuzosin, on urinary disorders in men with prostatic adenoma. Intermediate results of a European multicenter study]. ( Jardin, A, 1988)
"Silodosin is a novel, more selective alpha-blocker, which is specific to the lower urinary tract and may have fewer side effects than other alpha-blockers."2.55Silodosin for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia. ( Dahm, P; Jung, JH; Kim, J; Kim, MH; MacDonald, R; Reddy, B, 2017)
" α(1) Blockers generally lead to more adverse effects compared with placebo, and those caused by terazosin were more frequent than others."2.49The efficacy and safety of alpha-1 blockers for benign prostatic hyperplasia: an overview of 15 systematic reviews. ( Liu, Y; Mao, C; Qin, X; Yang, K; Yang, Z; Yuan, J, 2013)
"Alfuzosin is a uroselective alpha(1)-blocker that relaxes the smooth muscle of the bladder neck and prostate gland to alleviate BPH symptoms."2.43Efficacy and safety of alfuzosin 10 mg once daily in the treatment of symptomatic benign prostatic hyperplasia. ( Kuritzky, L; Rosenberg, MT; Sadovsky, R, 2006)
"The progression of benign prostatic hyperplasia (BPH) can be defined as a deterioration of clinical variables such as lower urinary tract symptoms (LUTS), health-related quality of life and peak flow rate, increased prostate size, or unfavourable outcomes such as acute urinary retention (AUR) and BPH-related surgery."2.43The natural history of benign prostatic hyperplasia. ( Fitzpatrick, JM, 2006)
"Medical treatment for benign prostatic hyperplasia is reviewed by the author."2.42[Pharmacologic treatment of benign prostatic hyperplasia]. ( Romics, I, 2003)
" The confirmed efficacy, proven bioavailability and good cardiovascular safety profile support the use of this drug for the management of lower urinary tract symptoms secondary to benign prostate hyperplasia (BPH)."2.42Alfuzosin for the management of benign prostate hyperplasia. ( Lowe, FC; Weiner, DM, 2003)
"Tamsulosin has selectivity for the a alpha(1) and alpha(1d) receptor subtypes."2.42Role of the newer alpha, -adrenergic-receptor antagonists in the treatment of benign prostatic hyperplasia-related lower urinary tract symptoms. ( Lowe, FC, 2004)
"As alfuzosin has been shown to reduce PVR, this factor may help prevent recurrent retention following TWOC."2.41Does acute urinary retention respond to alpha-blockers alone? ( McNeill, SA, 2001)
" The most frequently reported adverse event potentially related to alpha blockade was dizziness, which occurred in 5."2.41Alfuzosin: overview of pharmacokinetics, safety, and efficacy of a clinically uroselective alpha-blocker. ( Roehrborn, CG, 2001)
" No dosage titration is required."2.41Alfuzosin: a review of the therapeutic use of the prolonged-release formulation given once daily in the management of benign prostatic hyperplasia. ( McKeage, K; Plosker, GL, 2002)
") formulation of alfuzosin has recently been developed in order to improve the convenience of dosing and to provide optimal pharmacokinetic coverage over a 24-h period."2.41Alfuzosin: a clinically uroselective alpha1-blocker. ( Höfner, K; Jonas, U, 2002)
"dizziness and orthostatic hypotension)."2.40A meta-analysis on the efficacy and tolerability of alpha1-adrenoceptor antagonists in patients with lower urinary tract symptoms suggestive of benign prostatic obstruction. ( Djavan, B; Marberger, M, 1999)
" A limited range of clinical studies have shown oral alfuzosin to be more effective than placebo (in studies of < or = 6 months duration), to have sustained effects on long term administration (< or = 30 months), and to be comparable with the alpha 1-adrenoceptor antagonist prazosin, in the symptomatic treatment of benign prostatic hyperplasia."2.38Alfuzosin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in benign prostatic hyperplasia. ( Fitton, A; McTavish, D; Wilde, MI, 1993)
" The follow-up included 3 visits: visit of inclusion in the program of patients with a previously prescribed drug of Alfuprost MR in a dosage of 10 mg once a day (visit "0"), visit 1 at 30 days (+/-5 days) later, and visit 2 at 90 days (+/-5 days) after inclusion in the study."1.72[The influence of alfuzosin monotherapy on the sexual function of patients with benign prostatic hyperplasia in real clinical practice (results of a Russian multicenter study)]. ( Bernikov, AN; Loran, OB; Pushkar, DY, 2022)
"The delayed presentation of spinal cord ischemia was precipitated by commencement of alpha-blockers for benign prostatic hyperplasia."1.51Successful reversal of isolated delayed spinal cord ischemia following endovascular abdominal aneurysm repair. ( Al-Jarrah, M; Al-Omari, MH; Aljarrah, Q; Alzoubi, A; Elheis, M; Jamal, A, 2019)
"Incidence of benign prostatic hyperplasia (BPH), one of the most common conditions affecting adult men, increases dramatically after the age of 50."1.42[Impact of alfuzosin 10 mg once daily on quality of life in Tunisian patients with lower urinary symptoms suggestive of benign prostatic hyperplasia]. ( Adbi, H; Ben Raies, N; Ben Rhouma, S; Binous, MY; H'sairi, M; Horchani, A; Mosbah, AT; Nouira, Y, 2015)
"Secondary outcomes of hypotension and head trauma were also significantly increased in the exposed cohort (odds ratios 1."1.42The risk of fall and fracture with the initiation of a prostate-selective α antagonist: a population based cohort study. ( Dixon, S; Fraser, LA; Hayward, J; Hwang, YJ; McArthur, E; Ordon, M; Welk, B, 2015)
"The standard gold care medications for benign prostatic hyperplasia (BPH) are the alpha-1-adrenergic antagonists, they are an effective medications and are generally well tolerated."1.40Alpha-1 adrenergic antagonists induced severe rhinitis in patients with benign prostatic hyperplasia. ( Hassoun, G; Kedem, E; Nassar, L; Shahar, E, 2014)
"Since trial results for benign prostatic hyperplasia phytotherapeutic agents are inconsistent, they may also be contaminated."1.36Investigating contamination of phytotherapy products for benign prostatic hyperplasia with alpha-blockers and 5alpha-reductase inhibitors. ( Adomat, H; Elterman, DS; Fleshner, N; Guns, E; Hersey, K; Lawrentschuk, N; Wood, CA, 2010)
"Doxazosin GITS treatment resulted in optimal management of BP within the normal range, especially in pharmacologically or physiologically hypertensive patients."1.36Effects of α-blocker 'add on' treatment on blood pressure in symptomatic BPH with or without concomitant hypertension. ( Chung, BH; Lee, SH; Mah, SY; Park, KK, 2010)
"Forty males with benign prostatic hyperplasia (BPH) applying to the Department of Urology with lower urinary tract symptoms (LUTS) were enrolled in the study consecutively."1.35Comparing the therapeutic outcome of different alpha-blocker treatments for BPH in the same individuals. ( Adayener, C; Akyol, I; Ates, F; Iseri, C; Senkul, T; Yilmaz, O, 2008)
"A novel slow release formulation of alfuzosin should improve compliance by reducing dosing to one 10 mg tablet per day."1.33Early symptom improvement of benign prostatic hyperplasia (BPH) treated with once daily alfuzosin. ( Casey, R; Elhilali, M; Kuzmarov, I; Nickel, JC; Saad, F; Valiquette, L, 2005)
"Alfuzosin 10 mg was well tolerated; the most common adverse event related to vasodilatation was dizziness/postural dizziness (3."1.33Long-term efficacy and safety of alfuzosin 10 mg once daily: a 2-year experience in 'real-life' practice. ( Alcaraz, A; Elhilali, M; Emberton, M; Hartung, R; Harving, N; Matzkin, H; Vallancien, G; van Moorselaar, RJ, 2006)
" Just 16 patients (3%) developed adverse events; measures undertaken were to modify the dosage or to interrupt the treatment (2 cases)."1.31[Prostatic benign hypertrophy: review of effectiveness, tolerance, and impact on quality of life of prolonged treatment with alfuzosin]. ( Ausín, I; Barajas, R; Gabriel, R; Vela Navarrete, R, 2000)
"Tamsulosin has a markedly lower re-treatment percentage than alfuzosin and terazosin."1.31Long-term risk of re-treatment of patients using alpha-blockers for lower urinary tract symptoms. ( de la Rosette, JJ; Floratos, DL; Kiemeney, LA; Kortmann, BB; Rossi, C; Sonke, GS, 2002)
"To construct and validate a short-form benign prostatic hypertrophy (BPH) health-related quality-of-life (HRQL) questionnaire which is more practical in use and as informative as the 20-item visual analogue scale questionnaire (QOL20) previously validated in French."1.30Construction and validation of a short-form benign prostatic hypertrophy health-related quality-of-life questionnaire. BPH Group in General Practice. ( Comet, D; Grange, JC; Lukacs, B; Thibault, P, 1997)

Research

Studies (186)

TimeframeStudies, this research(%)All Research%
pre-19902 (1.08)18.7374
1990's52 (27.96)18.2507
2000's92 (49.46)29.6817
2010's37 (19.89)24.3611
2020's3 (1.61)2.80

Authors

AuthorsStudies
Kenny, B1
Ballard, S1
Blagg, J1
Fox, D1
Meyer, MD2
Altenbach, RJ2
Basha, FZ2
Carroll, WA2
Condon, S1
Elmore, SW1
Kerwin, JF2
Sippy, KB2
Tietje, K2
Wendt, MD2
Hancock, AA2
Brune, ME2
Buckner, SA2
Drizin, I2
Bai, H1
Lebold, SA1
Lee, E1
Pratt, JK1
Pushkar, DY1
Loran, OB1
Bernikov, AN1
Ohyama, K1
Hori, Y1
Sugiura, M1
Martov, AG1
Ergakov, DV1
Minh, TD1
Thanh Ha, TN1
Duy, TN1
Hoang, NN1
PhamTien, D1
Thai, HP1
Thi, HN1
Thi Lan, PD1
Quoc, BP1
Ivkin, DY1
Povydysh, MN1
Cong, BN1
Krasnova, MV1
Dogan, M1
Kutluksaman, B1
Keles, I1
Karalar, M1
Halat, AO1
Jung, JH1
Kim, J1
MacDonald, R2
Reddy, B1
Kim, MH1
Dahm, P1
Walash, MI1
Belal, F1
Fathy, M1
Zayed, S1
Borg, H1
Aljarrah, Q1
Al-Omari, MH1
Elheis, M1
Al-Jarrah, M1
Jamal, A1
Alzoubi, A1
Praus, F1
Miernik, A1
Chung, JH1
Lee, JY2
Kang, DH1
Jo, JK1
Lee, JW2
Lee, SH2
Lee, KS4
Kim, TH1
Han, JH1
Lee, SW3
Maldonado-Ávila, M1
Manzanilla-García, HA1
Sierra-Ramírez, JA1
Carrillo-Ruiz, JD1
González-Valle, JC1
Rosas-Nava, E1
Guzman-Esquivel, J1
Labra-Salgado, IR1
Chang, DF1
Campbell, JR1
Colin, J1
Schweitzer, C1
Shahar, E1
Nassar, L1
Kedem, E1
Hassoun, G1
Kara, O1
Yazici, M1
Bulut, S1
Ozden, C1
Aktas, BK1
Deren, T1
Tagci, S1
Gokkaya, CS1
Baykam, MM1
Memis, A1
Salah Azab, S1
Elsheikh, MG1
Umul, M1
Altay, AB1
Bademkiran, F1
Turna, B1
Semerci, MB1
Apaydin, E1
Cikili, N1
Zhang, LT1
Park, K2
Chung, WS1
Kim, SW2
Hyun, JS1
Moon, DG1
Yang, SK1
Ryu, JK1
Yang, DY1
Moon, KH1
Min, KS1
Park, JK2
Barkin, J1
Diles, D1
Franks, B1
Berner, T1
Ben Rhouma, S1
H'sairi, M1
Adbi, H1
Binous, MY1
Nouira, Y1
Ben Raies, N1
Mosbah, AT1
Horchani, A1
Welk, B1
McArthur, E1
Fraser, LA1
Hayward, J1
Dixon, S1
Hwang, YJ1
Ordon, M1
Armarnik, S1
Mimouni, M1
Rosen, E1
Assia, EI1
Segev, F1
Minutoli, L1
Rinaldi, M1
Marini, H1
Irrera, N1
Crea, G1
Lorenzini, C1
Puzzolo, D1
Valenti, A1
Pisani, A1
Adamo, EB1
Altavilla, D1
Squadrito, F1
Micali, A1
Arikan, G1
Demir, O1
Yaman, A1
Bozkurt, O1
Saatci, AO1
Durak, I1
Esen, A1
Mamalis, N1
Bar-Yosef, Y1
Mabjeesh, NJ1
Laufer, M1
Neulander, EZ1
Kaver, I1
Matzkin, H5
Roehrborn, CG10
Rosen, RC1
Wiygul, J1
Babayan, RK1
Roumeguère, T1
Zouaoui Boudjeltia, K1
Hauzeur, C1
Schulman, C1
Vanhaeverbeek, M1
Wespes, E1
Kongkanand, A1
Chodchoy, V1
Lojanapiwat, B2
Pumpaisanchai, S1
Ratana-Olarn, K1
Sae-Tang, P1
Taweemonkongsap, T1
Tiong, HY1
Tibung, MJ1
Macalalag, M1
Li, MK1
Consigliere, D1
Kim, MK1
Cheon, J1
Chung, MK1
Chung, BH2
Leungwattanakij, S1
Watanachote, D1
Noppakulsatit, P1
Petchpaibuol, T1
Choeypunt, N1
Tongbai, T1
Wanamkang, T1
Permpongkosol, S2
Tantiwong, A1
Pripatnanont, C1
Akarasakul, D1
Kongwiwatanakul, S1
Chotikawanich, E1
Elterman, DS1
Lawrentschuk, N1
Guns, E1
Hersey, K1
Adomat, H1
Wood, CA1
Fleshner, N1
Park, KK1
Mah, SY1
Lee, YS2
Lee, HN1
Han, JY2
Choo, MS2
Song, K1
Kim, JC1
Cho, JS1
Alan, C1
Kırılmaz, B1
Koçoğlu, H1
Ersay, AR1
Ertung, Y1
Eren, AE1
Güner, S1
Mutlu, B1
Güner, E1
Taşçi, AI1
Karadağ, E1
Öner, S1
Budak, YU1
Atahan, Ö1
Giannakopoulos, XK1
Giotis, C1
Karkabounas, SCh1
Verginadis, II1
Simos, YV1
Peschos, D1
Evangelou, AM1
Krilad-O-Larn, S1
Ratana-O-Larn, K1
Öztürk, Mİ1
Kalkan, S1
Koca, O1
Güneş, M1
Akyüz, M1
Karaman, MI1
Sherman, JJ1
Welch, RW1
Hill, TM1
McEwen, C1
Theodossiadis, PG1
Achtsidis, V1
Theodoropoulou, S1
Tentolouris, N1
Komninos, C1
Fountas, KN1
Hwang, TI1
Chu, SH1
Lin, MS1
Chen, CS1
Lee, LM1
Chang, HC1
Yeh, SD1
Chen, WH1
Chiang, PH1
Lee, HJ1
Yuan, J1
Liu, Y1
Yang, Z1
Qin, X1
Yang, K1
Mao, C1
Ahtoy, P1
Chrétien, P1
Dupain, T1
Rauch, C1
Rouchouse, A1
Delfolie, A1
Pool, JL1
Kirby, RS2
Başar, MM1
Atan, A1
Ozergin, O1
Yildiz, M1
Doherty, AP1
Larson, TR1
Palea, S1
Barras, M1
Mottet, N1
Bressolle, F1
Delmas, V1
Robert, M1
Costa, P1
Borer, J1
Armstrong, P1
De Nunzio, C1
Franco, G1
Iori, F1
Leonardo, C1
Minardi, V1
Laurenti, C1
Van Kerrebroeck, P2
Nordling, J6
Lee, M1
Romics, I1
Weiner, DM1
Lowe, FC2
Marks, LS1
Gittelman, M1
Kim, D1
Forrest, J1
Jacobs, S1
Wyllie, MG1
Brown, GA1
Sussman, DO1
de Reijke, TM2
Klarskov, P1
Simon, HB1
McNeill, AS2
Rizvi, S1
Byrne, DJ2
Guay, DR1
McNeill, SA4
Hargreave, TB3
Bozlu, M1
Ulusoy, E1
Cayan, S1
Akbay, E2
Görür, S1
Emberton, M7
Elhilali, M6
Harving, N3
van Moorselaar, J1
Hartung, R3
Alcaraz, A4
Vallancien, G5
Annemans, L1
Cleemput, I1
Lamotte, M1
McNeill, A1
Hargreave, T1
Saad, F1
Nickel, JC2
Valiquette, L1
Casey, R1
Kuzmarov, I1
Wilt, TJ1
Egilmez, T1
Pourbagher, MA1
Guvel, S1
Kilinc, F1
Turunc, T1
Ozkardes, H1
McVary, KT1
Irani, J1
Armitage, JN1
van Moorselaar, RJ2
Kuritzky, L1
Rosenberg, MT1
Sadovsky, R1
Settas, G1
Fitt, AW1
Fitzpatrick, JM1
van Dijk, MM1
de la Rosette, JJ4
Michel, MC2
Desgrandchamps, F1
De La Taille, A1
Doublet, JD1
Elhilali, MM1
O'Leary, MP1
Wang, YS1
Tay, YK1
Kwok, C1
Lukacs, B10
Resnick, MI1
Kaplan, SA2
Gonzalez, RR1
Te, AE2
Sciarra, A1
Altan-Yaycioglu, R1
Yaycioglu, O1
Gul, U1
Pelit, A1
Adibelli, FM1
Akova, YA1
Cheung, CM1
Awan, MA1
Peh, KK1
Sandramouli, S1
Mariappan, P1
Brown, DJ1
Blouin, MC1
Blouin, J1
Perreault, S1
Lapointe, A1
Dragomir, A1
Gopi, SS1
Goodman, CM1
Robertson, A1
Kim, SY1
Kim, BH1
Dong, SH1
Kim, HJ1
Chang, YW1
Chang, R1
Kim, YW1
Gupta, VK1
Singh, AK1
Gupta, B1
Senkul, T1
Yilmaz, O1
Iseri, C1
Adayener, C1
Akyol, I1
Ates, F1
Buzelin, JM5
Hebert, M1
Blondin, P2
Jardin, A10
Hansen, BJ7
Mensink, HJ5
Walter, S2
Meyhoff, HH5
Larosa, M1
Ferretti, S1
Salsi, P1
Simonazzi, M1
Bensadoun, H4
Delauche-Cavallier, MC8
Stalla-Bourdillon, A1
Attali, P5
Milani, M1
Mautone, A1
Tucci, G1
Gentili, G1
Chisena, S1
Mandressi, A1
Zaroli, A1
Belloni, M1
Antonelli, D1
Bernasconi, S1
Buizza, C1
Schulman, CC1
De Sy, W1
Vandendris, M1
Tomas, M1
Santoni, JP2
Flyger, H3
Brasso, K1
Schou, J1
Thorup Andersen, J1
Mortensen, S3
Hald, T2
Wilde, MI1
Fitton, A1
McTavish, D1
Martelli, A1
Pacifico, P2
Casadei, G2
McCarthy, C4
Grange, JC6
Portet-Brunet, L1
MacCarthy, C1
Du Boys, B1
Grippon, P1
Lassale, C1
Leplège, A1
Thibault, P2
Mogensen, P1
Larsen, EH1
Roth, S2
Geffriaud-Ricouard, C4
Martorana, G1
Giberti, C1
Di Silverio, F1
von Heland, M1
Rigatti, P1
Colombo, R1
Gómez Sancha, F1
Fernández Arjona, M1
Peinado Ibarra, F1
Fernández Borrell, A1
Mínguez Martínez, R1
Pereira Sanz, I1
Fonteyne, E1
Kontturi, M1
Witjes, WP3
Khan, A1
Comet, D5
Riehmann, M1
Hendolin, N1
Zerbib, M1
Vignoli, GC1
Geffriaud, C1
Debruyne, FM2
Wijkstra, H1
Mazo, EB1
Matushevskiĭ, IA1
Nikitin, IuIu1
Chapple, CR2
Delauche Cavallier, MC1
Martin, D1
Angel, I1
Reis, RB1
Cologna, A1
Suaid, HJ1
Martins, AC1
Kohn, IJ1
Colloi, D1
Resel, L1
Vela-Casasempere, P1
Borras-Blasco, J1
Navarro-Ruiz, A1
Bèïque, L1
Por, CP1
Evans, MF1
Djavan, B1
Marberger, M1
Mc Carthy, C1
Höfner, K2
Claes, H1
Folkestad, B1
Speakman, MJ1
Daruwala, PD1
Mitchell, ID1
Shearer, MG1
Laval, KU2
van Cangh, P2
Sánchez-Chapado, M2
Guil, M2
Alfaro, V2
Badiella, L1
Fernández-Hernando, N2
Vela Navarrete, R1
Gabriel, R1
Barajas, R1
Ausín, I1
Fourcade, RO1
Clifford, GM1
Farmer, RD2
Badiella, LI1
Santoni, J1
Van Kerrebroeck, PE1
Souverein, PC1
Herings, RM1
Man in 't Veld, AJ1
Leufkens, HG1
Costantino, G1
Clementi, G1
Matera, M1
Dutkiewics, S1
Flannery, MT1
Narayan, P1
Chess-Williams, R1
McKeage, K1
Plosker, GL1
Kortmann, BB1
Rossi, C1
Sonke, GS1
Floratos, DL1
Kiemeney, LA1
van Kerrebroec, P1
Jonas, U1
Morita, T1
Kondo, S1
Teillac, P1
Carbin, BE1
Bauer, P1
Friskand, M1
Moyse, D1
Ramsay, JW1
Scott, GI1
Whitfield, HN1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prophylactic Tamsulosin in Prevention of Post-operative Urinary Retention in Men After Transanal Endoscopic Microsurgery: A Multicenter Randomized, Double-blind, Placebo-controlled Clinical Trial[NCT03314025]Phase 2158 participants (Anticipated)Interventional2017-10-06Recruiting
The Effects of Systemic Alfuzosin and Tamsulosin Hydrochloride on Choroidal Thickness and Pupil Diameter Sizes in Cases With Benign Prostatic Hyperplasia[NCT03144596]Phase 463 participants (Actual)Interventional2015-10-29Completed
The Long Term Effects of Alfuzosin (Xatral XL) in LUTS/BPH Patients: Evaluation of Symptom-specific Goal Achievement According to Symptom Improvement, Bladder Outlet Obstruction Grade and Bladder Contractility[NCT00836823]Phase 4130 participants (Actual)Interventional2005-12-31Completed
Long-Term, Efficacy and Safety of Alfuzosin 10 MG OD on the Risk of Acute Urinary Retention and the Need for Surgery in Patients With BPH. A Two Year, Randomized, Multicenter, Double-Blind, Parallel Group, Placebo-Controlled Study.[NCT00029822]Phase 31,522 participants (Actual)Interventional2001-05-31Completed
Research on Benefit of Umooze as Add-on Therapy in Benign Prostatic Hyperplasia[NCT02313233]41 participants (Actual)Interventional2013-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

International Prostate Symptom Score (IPSS)

It's 7- item urinary symptom severity scale. The answers are assigned points from 0 to 5, indicating increasing severity. The total score can therefore range from 0 to 35 points. (NCT02313233)
Timeframe: 56 days

,
Interventionunits on a scale (Mean)
International prostate symptom scoreDifference in IPSS between V1 and V6
Placebo13.6-5.94
Umooze9.83-3.39

International Prostate Symptom Score (IPSS) Between V1 and V6 in the Same Medication for More Than 12 Months

It's 7- item urinary symptom severity scale. The answers are assigned points from 0 to 5, indicating increasing severity. The total score can therefore range from 0 to 35 points. (NCT02313233)
Timeframe: 56 days

,
Interventionunits on a scale (Mean)
International prostate symptom scoreDifference in IPSS between V1 and V6
Placebo14.33-4.33
Umooze11.00-9.50

Maximum Flow Rate (Qmax)

It's used to determine the degree of urinary difficulty. (NCT02313233)
Timeframe: 56 days

,
Interventionml/ sec (Mean)
QmaxDifference of Qmax between V1 and V6
Placebo12.722.49
Umooze14.42.88

Postvoid Residual Volume (PVR)

The PVR urine test measures the amount of urine left in the bladder after urination. (NCT02313233)
Timeframe: 56 days

,
Interventionml (Mean)
Post- Void Residual Volume (PVR)Difference of PVR between V1 and V6
Placebo67.214.8
Umooze35.3-8.39

Prostate Volume

It's related to progression of benign prostatic hyperplasia (BPH). (NCT02313233)
Timeframe: 56 days

,
Interventioncm^3 (Mean)
Prostate VolumeDifference of prostate volume between V1 and V6
Placebo38.2-1.33
Umooze29.1-8.17

Prostate-specific Antigen (PSA) Level

Serum PSA test measures the amount of prostate- specific antigen in the blood. As a man's prostate enlarges with age, the amount of PSA in the blood normally increases. (NCT02313233)
Timeframe: 56 days

,
Interventionng/ml (Mean)
Prostate- specific Antigen (PSA)Difference of PSA between V1 and V6
Placebo2.220.26
Umooze1.670.14

Quality of Life (QoL) Index Between V1 and V6 for the Subjects Taking 0.4 mg Harnalidge

The Quality of Life (QoL) is a single question with scores of 0~6 point and corresponding to the assessment index ranging from delighted to terrible. (NCT02313233)
Timeframe: 56 days

,
Interventionunits on a scale (Mean)
Quality of Life (QoL)Difference of QoL between V1 and V6
Placebo3.27-0.09
Umooze2.73-0.82

Quality- Of- Life Index (QoL)

The QoL index is a single question with scores of 0~6 point and corresponding to the assessment index ranging from delighted to terrible. (NCT02313233)
Timeframe: 56 days

,
Interventionunits on a scale (Mean)
Quality-of-Life (QoL)Difference of QoL between V1 and V6
Placebo3.22-0.56
Umooze2.72-0.61

Reviews

39 reviews available for alfuzosin and Adenoma, Prostatic

ArticleYear
Pharmacological options in the treatment of benign prostatic hyperplasia.
    Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Controlle

1997
Silodosin for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia.
    The Cochrane database of systematic reviews, 2017, 11-22, Volume: 11

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Humans; Indoles; Lower Urinary Tract Symptoms; Male;

2017
[LUTS in BPH patients : Comparison of silodosin versus tamsulosin, naftopidil, alfuzosin and placebo for the treatment of lower urinary tract symptoms].
    Der Urologe. Ausg. A, 2019, Volume: 58, Issue:7

    Topics: Adrenergic alpha-1 Receptor Antagonists; Humans; Indoles; Lower Urinary Tract Symptoms; Male; Naphth

2019
Apoptotic Pathways Linked to Endocrine System as Potential Therapeutic Targets for Benign Prostatic Hyperplasia.
    International journal of molecular sciences, 2016, Aug-11, Volume: 17, Issue:8

    Topics: Apoptosis; Dutasteride; Endocrine System; Finasteride; Humans; Male; Prostatic Hyperplasia; Quinazol

2016
[Alpha blockers in use for symptomatic benign prostatic hyperplasia--are all drugs born equal?].
    Harefuah, 2008, Volume: 147, Issue:6

    Topics: Adrenergic alpha-Antagonists; Doxazosin; Evidence-Based Medicine; Humans; Male; Prazosin; Prostatic

2008
Medical therapy options for aging men with benign prostatic hyperplasia: focus on alfuzosin 10 mg once daily.
    Clinical interventions in aging, 2008, Volume: 3, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aged; Aging; Dose-Response Relationship, Drug; Drug Administration Sch

2008
Watchful waiting in benign prostatic hyperplasia.
    Current opinion in urology, 2009, Volume: 19, Issue:1

    Topics: Adrenergic alpha-Antagonists; Disease Progression; Humans; Male; Prostate; Prostate-Specific Antigen

2009
Is there a rationale for the chronic use of phosphodiesterase-5 inhibitors for lower urinary tract symptoms secondary to benign prostatic hyperplasia?
    BJU international, 2009, Volume: 104, Issue:4

    Topics: Aged; Carbolines; Erectile Dysfunction; Humans; Imidazoles; Male; Middle Aged; Phosphodiesterase Inh

2009
The efficacy and safety of alpha-1 blockers for benign prostatic hyperplasia: an overview of 15 systematic reviews.
    Current medical research and opinion, 2013, Volume: 29, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Doxazosin; Humans; Male; Naphthalenes; Piperazines; Prostat

2013
Clinical significance of alpha1-adrenoceptor selectivity in the management of benign prostatic hyperplasia.
    International urology and nephrology, 2001, Volume: 33, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Blood-Brain Barrier; Doxazosin; Humans; Male;

2001
Current treatment options for benign prostatic hyperplasia and their impact on sexual function.
    Urology, 2003, Volume: 61, Issue:4

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Erectile Dysfunction; Finasteride; Human

2003
Alfuzosin hydrochloride for the treatment of benign prostatic hyperplasia.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2003, Jul-15, Volume: 60, Issue:14

    Topics: Adrenergic alpha-Antagonists; Clinical Trials as Topic; Delayed-Action Preparations; Drug Interactio

2003
[Pharmacologic treatment of benign prostatic hyperplasia].
    Orvosi hetilap, 2003, Sep-14, Volume: 144, Issue:37

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Doxazosin; Enzyme Inhibitors; Finasterid

2003
Alfuzosin for the management of benign prostate hyperplasia.
    Expert opinion on pharmacotherapy, 2003, Volume: 4, Issue:11

    Topics: Adrenergic alpha-Antagonists; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic;

2003
Extended-release alfuzosin hydrochloride: a new alpha-adrenergic receptor antagonist for symptomatic benign prostatic hyperplasia.
    The American journal of geriatric pharmacotherapy, 2004, Volume: 2, Issue:1

    Topics: Adrenergic alpha-Antagonists; Clinical Trials as Topic; Delayed-Action Preparations; Drug Administra

2004
Role of the newer alpha, -adrenergic-receptor antagonists in the treatment of benign prostatic hyperplasia-related lower urinary tract symptoms.
    Clinical therapeutics, 2004, Volume: 26, Issue:11

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Clinical Trials as Topic; Hum

2004
Alfuzosin for treatment of lower urinary tract symptoms compatible with benign prostatic hyperplasia: a systematic review of efficacy and adverse effects.
    Urology, 2005, Volume: 66, Issue:4

    Topics: Adrenergic alpha-Antagonists; Humans; Male; Prostatic Hyperplasia; Quinazolines; Randomized Controll

2005
Alfuzosin for symptomatic benign prostatic hyperplasia: long-term experience.
    The Journal of urology, 2006, Volume: 175, Issue:1

    Topics: Adrenergic alpha-Antagonists; Humans; Male; Prostatic Hyperplasia; Quality of Life; Quinazolines; Se

2006
Efficacy and safety of alfuzosin 10 mg once daily in the treatment of symptomatic benign prostatic hyperplasia.
    International journal of clinical practice, 2006, Volume: 60, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Prostatic Hyperpla

2006
The natural history of benign prostatic hyperplasia.
    BJU international, 2006, Volume: 97 Suppl 2

    Topics: Adrenergic alpha-Antagonists; Age Factors; Aged; Aged, 80 and over; Controlled Clinical Trials as To

2006
Definition of at-risk patients: dynamic variables.
    BJU international, 2006, Volume: 97 Suppl 2

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Disease Progression; Humans; M

2006
Effects of alpha(1)-adrenoceptor antagonists on male sexual function.
    Drugs, 2006, Volume: 66, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic Antagonists; Adult; Aged; Doxazosin; Ejaculation

2006
Alfuzosin: an alpha1-receptor blocker for the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Huma

2006
Treatment and pharmacologic management of BPH in the context of common comorbidities.
    The American journal of managed care, 2006, Volume: 12, Issue:5 Suppl

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Azasteroids; Cardiovascular Diseases; Co

2006
Clinical results with alpha-blockers in patients with symptomatic benign prostatic hyperplasia.
    Progress in clinical and biological research, 1994, Volume: 386

    Topics: Adrenergic alpha-Antagonists; Controlled Clinical Trials as Topic; Humans; Male; Multicenter Studies

1994
Alfuzosin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in benign prostatic hyperplasia.
    Drugs, 1993, Volume: 45, Issue:3

    Topics: Adrenergic alpha-Antagonists; Humans; Male; Prostatic Hyperplasia; Quinazolines

1993
Using a large clinical database to assess the effectiveness of alfuzosin.
    European urology, 1997, Volume: 32 Suppl 2

    Topics: Adrenergic alpha-Antagonists; Aged; Cost-Benefit Analysis; Databases, Factual; Decision Making, Comp

1997
[Alpha blockers in the treatment of benign hyperplasia of the prostate].
    Revista clinica espanola, 1997, Volume: 197, Issue:5

    Topics: Adrenergic alpha-Antagonists; Doxazosin; Humans; Indoramin; Male; Phenoxybenzamine; Prazosin; Prosta

1997
Clinical uroselectivity of alfuzosin in the treatment of benign prostatic hyperplasia.
    European urology, 1998, Volume: 33 Suppl 2

    Topics: Adrenergic alpha-Antagonists; Blood Pressure; Delayed-Action Preparations; Humans; Hypotension, Orth

1998
Pharmacotherapy for benign prostatic hyperplasia--the potential for alpha 1-adrenoceptor subtype-specific blockade.
    British journal of urology, 1998, Volume: 81 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Clinical Trials as Topic; Doxazosin; Hormones; Humans; Male; Patient S

1998
A meta-analysis on the efficacy and tolerability of alpha1-adrenoceptor antagonists in patients with lower urinary tract symptoms suggestive of benign prostatic obstruction.
    European urology, 1999, Volume: 36, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Controlled Clinical Trials as Topic; Dizzines

1999
Medical therapy for benign prostatic hyperplasia: a review of the literature.
    European urology, 2000, Volume: 38, Issue:1

    Topics: Adrenergic alpha-Antagonists; Doxazosin; Finasteride; Humans; Indoramin; Male; Prazosin; Prostatic H

2000
Postvoid residual urine in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: pooled analysis of eleven controlled studies with alfuzosin.
    Urology, 2001, Volume: 57, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Humans; Male; Middle Aged

2001
Does acute urinary retention respond to alpha-blockers alone?
    European urology, 2001, Volume: 39 Suppl 6

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Humans; Male; Prostatic Hyperplasia; Quinazolines; Trea

2001
Worldwide experience with alfuzosin and tamsulosin.
    Urology, 2001, Volume: 58, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Controlled Clinical Trials as Topic; Hu

2001
Alfuzosin: overview of pharmacokinetics, safety, and efficacy of a clinically uroselective alpha-blocker.
    Urology, 2001, Volume: 58, Issue:6 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Aged; Drug Administration Schedule; Humans; Male; Prostatic Hyperplasi

2001
The use of alpha-adrenoceptor antagonists in lower urinary tract disease.
    Expert opinion on pharmacotherapy, 2002, Volume: 3, Issue:2

    Topics: Adrenergic alpha-Antagonists; Humans; Hypertension; Male; Prostatic Hyperplasia; Quinazolines; Sulfo

2002
Alfuzosin: a review of the therapeutic use of the prolonged-release formulation given once daily in the management of benign prostatic hyperplasia.
    Drugs, 2002, Volume: 62, Issue:4

    Topics: Absorption; Adrenergic alpha-Antagonists; Aged; Area Under Curve; Clinical Trials as Topic; Delayed-

2002
Alfuzosin: a clinically uroselective alpha1-blocker.
    World journal of urology, 2002, Volume: 19, Issue:6

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Aged; Animals; Clinical Trials, Phase III as Top

2002

Trials

72 trials available for alfuzosin and Adenoma, Prostatic

ArticleYear
The Effects of Systemic Alfuzosin and Tamsulosin Hydrochloride on Choroidal Thickness and Pupil Diameter Sizes in Cases with Benign Prostatic Hyperplasia.
    Current eye research, 2017, Volume: 42, Issue:12

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and over; Choroid; Color Vision; Diagnostic

2017
Evaluation of patient outcome after discontinuation of alfuzosin treatment for benign prostatic hyperplasia: a multicentre, prospective study.
    International journal of clinical practice, 2013, Volume: 67, Issue:9

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Humans; Lower Urinary Tract Symptoms; Male; Prospecti

2013
A comparative study on the use of tamsulosin versus alfuzosin in spontaneous micturition recovery after transurethral catheter removal in patients with benign prostatic growth.
    International urology and nephrology, 2014, Volume: 46, Issue:4

    Topics: Acute Disease; Adrenergic alpha-1 Receptor Antagonists; Aged; Device Removal; Humans; Male; Middle A

2014
Prospective masked comparison of intraoperative floppy iris syndrome severity with tamsulosin versus alfuzosin.
    Ophthalmology, 2014, Volume: 121, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Cross-Sectional Studies; Double-Blind Method; Humans;

2014
Is the double dose alpha-blocker treatment superior than the single dose in the management of patients suffering from acute urinary retention caused by benign prostatic hyperplasia?
    Urology journal, 2014, Jul-08, Volume: 11, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and over; Dizziness; Drug Therapy, Combinati

2014
Multicenter, prospective, comparative cohort study evaluating the efficacy and safety of alfuzosin 10 mg with regard to blood pressure in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia with or without antihypertensive med
    Clinical interventions in aging, 2015, Volume: 10

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Humans; Hypertension; Lowe

2015
Alfuzosin 10 mg once daily increases the chances of successful trial without catheter after acute urinary retention secondary to benign prostate hyperplasia.
    Urologia internationalis, 2009, Volume: 83, Issue:1

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Aged; Double-Blind Method; Humans; Male; Prostatic Hype

2009
An open, non-comparative, multicentre study on the impact of alfuzosin on sexual function using the Male Sexual Health Questionnaire in patients with benign prostate hyperplasia.
    International journal of clinical practice, 2010, Volume: 64, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Ejaculation; Humans; Male; Middle Aged; Patient Satis

2010
Sexuality and management of benign prostatic hyperplasia with alfuzosin: SAMBA Thailand.
    The journal of sexual medicine, 2010, Volume: 7, Issue:9

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Ejaculation; Erectile Dysfunction; Humans; Male; Midd

2010
Most bothersome symptom and symptom specific goal achievement in patients with benign prostatic obstruction: a prospective open label study.
    The Journal of urology, 2011, Volume: 185, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Goals; Humans; Male; Middle Aged; Prospective Studies; Pros

2011
The long-term effect of alfuzosin in patients with lower urinary tract symptoms suggestive of benign prostate hyperplasia: evaluation of voiding and storage function with respect to bladder outlet obstruction grade and contractility.
    Urology, 2011, Volume: 77, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Muscle

2011
Randomized crossover comparison of tamsulosin and alfuzosin in patients with urinary disturbances caused by benign prostatic hyperplasia.
    International urology and nephrology, 2011, Volume: 43, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Cross-Over Studies; Humans; Male; Middle Aged; Prosta

2011
Effects of pulsed electromagnetic fields on benign prostate hyperplasia.
    International urology and nephrology, 2011, Volume: 43, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Electromagnetic Fields; Humans; Male; Organ Size; Pro

2011
Treatment with a uroselective α1-blocker improves voiding and sexual function: a study in Thai men with lower urinary tract symptoms.
    The journal of sexual medicine, 2011, Volume: 8, Issue:9

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Erectile Dysfunction; Humans; Male; Middle Aged; Peni

2011
Efficacy of alfuzosin and sildenafil combination in male patients with lower urinary tract symptoms.
    Andrologia, 2012, Volume: 44 Suppl 1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Drug Therapy, Combination; Humans; Male; Middl

2012
Alfuzosin, an alpha1-adrenoceptor antagonist for the treatment of benign prostatic hyperplasia: once daily versus 3 times daily dosing in healthy subjects.
    International journal of clinical pharmacology and therapeutics, 2002, Volume: 40, Issue:7

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Analysis of Variance; A

2002
Prostatic tissual distribution of alfuzosin in patients with benign prostatic hyperplasia following repeated oral administration.
    European urology, 2003, Volume: 44, Issue:1

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Aged; Biological Availability; Biopsy, Needle; D

2003
Safety and efficacy of alfuzosin 10 mg once-daily in the treatment of lower urinary tract symptoms and clinical benign prostatic hyperplasia: a pooled analysis of three double-blind, placebo-controlled studies.
    BJU international, 2003, Volume: 92, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Erectile Dysfunct

2003
First dose efficacy of alfuzosin once daily in men with symptomatic benign prostatic hyperplasia.
    Urology, 2003, Volume: 62, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Cross-Over Studies; Dru

2003
Comparative efficacy of two alpha-adrenoreceptor antagonists, doxazosin and alfuzosin, in patients with lower urinary tract symptoms from benign prostatic enlargement.
    BJU international, 2004, Volume: 93, Issue:6

    Topics: Adrenergic alpha-Antagonists; Double-Blind Method; Doxazosin; Drug Administration Schedule; Humans;

2004
Prostate size influences the outcome after presenting with acute urinary retention.
    BJU international, 2004, Volume: 94, Issue:4

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Aged; Cohort Studies; Follow-Up Studies; Humans; Male;

2004
Alfuzosin 10 mg once daily in the management of acute urinary retention: results of a double-blind placebo-controlled study.
    Urology, 2005, Volume: 65, Issue:1

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Aged; Biomarkers; Combined Modality Therapy; Disease-Fr

2005
Efficacy and safety of two doses (10 and 15 mg) of alfuzosin or tamsulosin (0.4 mg) once daily for treating symptomatic benign prostatic hyperplasia.
    BJU international, 2005, Volume: 95, Issue:7

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Double-Blin

2005
Three months' treatment with the alpha1-blocker alfuzosin does not affect total or transition zone volume of the prostate.
    Prostate cancer and prostatic diseases, 2006, Volume: 9, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Confidence Intervals; Dose-Response Relations

2006
Alfuzosin 10 mg once daily prevents overall clinical progression of benign prostatic hyperplasia but not acute urinary retention: results of a 2-year placebo-controlled study.
    BJU international, 2006, Volume: 97, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aged; Disease Progression; Double-Blind Method; Humans; Male; Middle A

2006
The beneficial effect of alfuzosin 10 mg once daily in 'real-life' practice on lower urinary tract symptoms (LUTS), quality of life and sexual dysfunction in men with LUTS and painful ejaculation.
    BJU international, 2006, Volume: 97, Issue:6

    Topics: Adrenergic alpha-Antagonists; Aged; Ejaculation; Humans; Male; Middle Aged; Pain; Prostatic Hyperpla

2006
Rapid onset of action with alfuzosin 10 mg once daily in men with benign prostatic hyperplasia: a randomized, placebo-controlled trial.
    Prostate cancer and prostatic diseases, 2007, Volume: 10, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aged; Double-Blind Method; Humans; Male; Middle Aged; Placebos; Prosta

2007
Combination of alfuzosin and sildenafil is superior to monotherapy in treating lower urinary tract symptoms and erectile dysfunction.
    European urology, 2007, Volume: 51, Issue:6

    Topics: Adrenergic alpha-Antagonists; Aged; Drug Therapy, Combination; Erectile Dysfunction; Humans; Male; M

2007
The effects of two systemic alpha1-adrenergic blockers on pupil diameter: a prospective randomized single-blind study.
    Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 375, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Humans; Intraoperative

2007
A prospective pilot study to validate the management protocol for patients presenting with acute urinary retention: a community-based, nonhospitalised protocol.
    TheScientificWorldJournal, 2006, Jun-02, Volume: 6

    Topics: Adrenergic alpha-Antagonists; Aged; Catheterization; Community Health Services; Humans; Male; Middle

2006
Alpha-blocking treatment with alfuzosin in symptomatic benign prostatic hyperplasia: comparative study with prazosin. The PRAZALF Group.
    British journal of urology, 1993, Volume: 72, Issue:6

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Double-Blind Method; Humans; Male; Middle Age

1993
[Alfuzosin in the treatment of benign prostatic hypertrophy].
    Journal d'urologie, 1993, Volume: 99, Issue:6

    Topics: Adrenergic alpha-Antagonists; Humans; Male; Prostatic Hyperplasia; Quality of Life; Quinazolines; Ur

1993
Alfuzosin in the treatment of benign prostatic hyperplasia: effects on symptom scores, urinary flow rates and residual volume. A multicentre, double-blind, placebo-controlled trial. ALFECH Study Group.
    Scandinavian journal of urology and nephrology. Supplementum, 1994, Volume: 157

    Topics: Adrenergic alpha-Antagonists; Aged; Double-Blind Method; Humans; Male; Middle Aged; Prostatic Hyperp

1994
Long-term treatment of benign prostatic hyperplasia with alfuzosin: a 24-30 month survey. BPHALF Group.
    British journal of urology, 1994, Volume: 74, Issue:5

    Topics: Adrenergic alpha-Antagonists; Aged; Blood Pressure; Follow-Up Studies; Heart Rate; Humans; Long-Term

1994
[Assessment of the effects of alfuzosin on miction with dynamic echography].
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 1994, Volume: 66, Issue:4 Suppl

    Topics: Adrenergic alpha-Antagonists; Double-Blind Method; Humans; Male; Prostatic Hyperplasia; Quinazolines

1994
Multicenter observational trial on symptomatic treatment of benign prostatic hyperplasia with alfuzosin: clinical evaluation of impact on patient's quality of life. The Italian Alfuzosin Cooperative Group.
    European urology, 1995, Volume: 27, Issue:2

    Topics: Activities of Daily Living; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Analysis o

1995
Belgian multicenter clinical study of alfuzosin, a selective alpha 1-blocker, in the treatment of benign prostatic hyperplasia. The Alfuzosin Belgian Group.
    Acta urologica Belgica, 1994, Volume: 62, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Cross-Over Studies; Double-Blind Method; Humans; Male; Mi

1994
Validation of the self-administered Danish Prostatic Symptom Score (DAN-PSS-1) system for use in benign prostatic hyperplasia.
    British journal of urology, 1995, Volume: 76, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Prostatic H

1995
Effect of alfuzosin on quality of life in benign prostatic hyperplasia patients: preliminary results. Italian Alfuzosin Co-Operative Group.
    European urology, 1993, Volume: 24 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Aged; Humans; Male; Middle Aged; Prostatic Hyperplasia; Quality of Lif

1993
Long-term quality of life in patients with benign prostatic hypertrophy: preliminary results of a cohort survey of 7,093 patients treated with an alpha-1-adrenergic blocker, alfuzosin. QOL BPH Study Group in General Practice.
    European urology, 1993, Volume: 24 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Aged; Cohort Studies; Follow-Up Studies; Humans; Male; Prospective Stu

1993
Symptomatic outcome of transurethral prostatectomy, alpha-blockade and placebo in the treatment of benign prostatic hyperplasia. Evaluation of treatment with the Danish Prostatic Symptom Score (DAN-PSS-1) system. The ALFECH Study Group.
    Scandinavian journal of urology and nephrology, 1996, Volume: 30, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Follow-Up Studies; Humans; Male; Middle Aged;

1996
Safety profile of 3 months' therapy with alfuzosin in 13,389 patients suffering from benign prostatic hypertrophy.
    European urology, 1996, Volume: 29, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aged; Drug Evaluation; Follow-Up Studies; France; Humans; Male; Produc

1996
Prospective study of men with clinical benign prostatic hyperplasia treated with alfuzosin by general practitioners: 1-year results.
    Urology, 1996, Volume: 48, Issue:5

    Topics: Adrenergic alpha-Antagonists; Aged; Disease Progression; Family Practice; Humans; Male; Middle Aged;

1996
Placebo effects in the pharmacological treatment of uncomplicated benign prostatic hyperplasia. The ALFECH Study Group.
    Scandinavian journal of urology and nephrology, 1996, Volume: 30, Issue:5

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Denmark; Double-Blind Method; Drug Administra

1996
Efficacy and safety of sustained-release alfuzosin 5 mg in patients with benign prostatic hyperplasia. ALGEBI Study Group.
    European urology, 1997, Volume: 31, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Blood Pressure; Delayed-Action Preparations;

1997
Clinical uroselectivity: evidence from patients treated with slow-release alfuzosin for symptomatic benign prostatic obstruction.
    British journal of urology, 1997, Volume: 79, Issue:6

    Topics: Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases

1997
Effects of short-term treatment with the alpha 1-blocker alfuzosin on urodynamic pressure/flow parameters in patients with benign prostatic hyperplasia.
    European urology, 1997, Volume: 32, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Double-Blind Method; Follow-Up Studies; Human

1997
Comparison of tamsulosin with alfuzosin in the treatment of patients with lower urinary tract symptoms suggestive of bladder outlet obstruction (symptomatic benign prostatic hyperplasia). The European Tamsulosin Study Group.
    British journal of urology, 1997, Volume: 80, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aged; Blood Pressure; Humans; Male; Middle Aged; Prostatic Hyperplasia

1997
Comparison of the Danish Prostatic Symptom Score with the International Prostatic Symptom Score, the Madsen-Iversen and Boyarsky symptom indexes. ALFECH Study Group.
    British journal of urology, 1998, Volume: 81, Issue:1

    Topics: Adrenergic alpha-Antagonists; Double-Blind Method; Humans; Hyperthermia, Induced; Male; Microwaves;

1998
Clinical uroselectivity: a 3-year follow-up in general practice. BPH Group in General Practice.
    European urology, 1998, Volume: 33 Suppl 2

    Topics: Adrenergic alpha-Antagonists; Aged; Family Practice; Follow-Up Studies; Humans; Male; Middle Aged; P

1998
Intermittent alpha-blocker therapy in the treatment of men with lower urinary tract symptoms.
    Urology, 1998, Volume: 52, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aged; Humans; Male; Middle Aged; Prospective Studies; Prostatic Hyperp

1998
Sustained-release alfuzosin, finasteride and the combination of both in the treatment of benign prostatic hyperplasia. European ALFIN Study Group.
    European urology, 1998, Volume: 34, Issue:3

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Aged; Delayed-Action Preparations; Doubl

1998
Are the new selective alpha-blockers better than non-selective alpha-blockers for benign prostatic hyperplasia?
    Canadian family physician Medecin de famille canadien, 1998, Volume: 44

    Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Double-Blind Method; Humans; Hypotension; Mal

1998
Long-term treatment of benign prostatic hyperplasia with alfuzosin: a 12-18 month assessment. BPHALF Group.
    British journal of urology, 1993, Volume: 72, Issue:5 Pt 1

    Topics: Adrenergic alpha-Antagonists; Aged; Double-Blind Method; Humans; Male; Middle Aged; Prostatic Hyperp

1993
[Prospective follow-up of 3,228 patients suffering from clinical benign prostatic hyperplasia (BPH) treated for 3 years wi alfuzosin in general practice. BPH Group in General Practice].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 1999, Volume: 9, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Cohort Studies; Follow-Up Studies; France; Hu

1999
Tamsulosin 0.4 mg once daily: effect on sexual function in patients with lower urinary tract symptoms suggestive of benign prostatic obstruction.
    European urology, 1999, Volume: 36, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Drug Therapy, Combinati

1999
Sustained-release alfuzosin and trial without catheter after acute urinary retention: a prospective, placebo-controlled.
    BJU international, 1999, Volume: 84, Issue:6

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Delayed-Action Preparations; Follow-Up Studie

1999
History of 7,093 patients with lower urinary tract symptoms related to benign prostatic hyperplasia treated with alfuzosin in general practice up to 3 years.
    European urology, 2000, Volume: 37, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aged; Cohort Studies; Disease Progression; Family Practice; Follow-Up

2000
Efficacy and safety of a new prolonged release formulation of alfuzosin 10 mg once daily versus alfuzosin 2.5 mg thrice daily and placebo in patients with symptomatic benign prostatic hyperplasia. ALFORTI Study Group.
    European urology, 2000, Volume: 37, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aged; Delayed-Action Preparations; Double-Blind Method; Drug Administr

2000
Safety and efficacy of sustained-release alfuzosin on lower urinary tract symptoms suggestive of benign prostatic hyperplasia in 3,095 Spanish patients evaluated during general practice.
    European urology, 2000, Volume: 37, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aged; Analysis of Variance; Blood Pressure Monitoring, Ambulatory; Del

2000
Safety, efficacy and impact on Patients' quality of life of a long-term treatment with the alpha(1)-blocker alfuzosin in symptomatic patients with BPH. The Italian Alfuzosin Co-Operative Group.
    European urology, 2000, Volume: 37, Issue:6

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Prostatic Hyperpla

2000
[Efficiency and tolerance of terazosine in ambulatory patients with benign prostatic hypertrophy: comparative randomized and double-blind trial versus alfuzosin. The MG Terazosine Group].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2000, Volume: 10, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Ambulatory Care; Double-Blind Method; Humans;

2000
The clinical uroselectivity of alfuzosin is not significantly affected by the age of patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia.
    BJU international, 2000, Volume: 86, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adult; Age Factors; Aged; Humans; Male; Middle Aged; Prostatic Hyperpl

2000
The efficacy and safety of a new once-a-day formulation of an alpha-blocker.
    European urology, 2001, Volume: 39 Suppl 6

    Topics: Adrenergic alpha-Antagonists; Aged; Drug Administration Schedule; Humans; Male; Middle Aged; Prostat

2001
[Long-term therapy of benign prostatic hyperplasia. Our experience].
    Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 2001, Volume: 53, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aged; Doxazosin; Finasteride; Follow-Up Studies; Humans; Male; Mepartr

2001
Efficacy and safety of once-daily alfuzosin in the treatment of lower urinary tract symptoms and clinical benign prostatic hyperplasia: a randomized, placebo-controlled trial.
    Urology, 2001, Volume: 58, Issue:6

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Canada; Double-Blind

2001
Long-term safety and efficacy of a once-daily formulation of alfuzosin 10 mg in patients with symptomatic benign prostatic hyperplasia: open-label extension study.
    European urology, 2002, Volume: 41, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Delayed-Action Preparations; Dose-Response Re

2002
Urinary flow rates in patients with benign prostatic hypertrophy following treatment with alfuzosin. DUALF Group.
    British journal of urology, 1992, Volume: 70, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Double-Blin

1992
Alfuzosin for treatment of benign prostatic hypertrophy. The BPH-ALF Group.
    Lancet (London, England), 1991, Jun-15, Volume: 337, Issue:8755

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Drug Evaluation; Humans; Male; Middle Aged; P

1991
Efficacy of alfuzosine (an alpha 1-adrenoreceptor blocking drug) in benign hyperplasia of the prostate.
    Scandinavian journal of urology and nephrology. Supplementum, 1991, Volume: 138

    Topics: Adrenergic alpha-Antagonists; Aged; Double-Blind Method; Humans; Male; Middle Aged; Prostatic Hyperp

1991
A double-blind controlled trial of a new alpha-1 blocking drug in the treatment of bladder outflow obstruction.
    British journal of urology, 1985, Volume: 57, Issue:6

    Topics: Adult; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Humans; Male; Middle Aged; Pro

1985
[Efficacy of an alpha-blocker, alfuzosin, on urinary disorders in men with prostatic adenoma. Intermediate results of a European multicenter study].
    Annales d'urologie, 1988, Volume: 22, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Europe; Huma

1988

Other Studies

75 other studies available for alfuzosin and Adenoma, Prostatic

ArticleYear
Structure-activity studies for a novel series of tricyclic substituted hexahydrobenz[e]isoindole alpha(1A) adrenoceptor antagonists as potential agents for the symptomatic treatment of benign prostatic hyperplasia (BPH).
    Journal of medicinal chemistry, 2000, Apr-20, Volume: 43, Issue:8

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cell Line; Dogs; Heterocyclic Compounds, 3-Ri

2000
Structure-activity studies for a novel series of bicyclic substituted hexahydrobenz[e]isoindole alpha1A adrenoceptor antagonists as potential agents for the symptomatic treatment of benign prostatic hyperplasia.
    Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cell Line; Dogs; Dox

2001
[The influence of alfuzosin monotherapy on the sexual function of patients with benign prostatic hyperplasia in real clinical practice (results of a Russian multicenter study)].
    Urologiia (Moscow, Russia : 1999), 2022, Issue:6

    Topics: Adrenergic alpha-Antagonists; Humans; Lower Urinary Tract Symptoms; Male; Prostatic Hyperplasia; Qua

2022
Evaluation of syncope association with α
    Die Pharmazie, 2019, 12-01, Volume: 74, Issue:12

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Doxazosin; Humans; Hypertension; Indoles; Male; Midd

2019
[The use of alfuzosin in the treatment of patients with acute urinary retention].
    Urologiia (Moscow, Russia : 1999), 2020, Issue:6

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Pro

2020
Linh Phu Khang Tue Tinh inhibited prostate proliferation in rats induced benign prostatic hyperplasia by testosterone propionate.
    Journal of ethnopharmacology, 2021, Oct-28, Volume: 279

    Topics: 5-alpha Reductase Inhibitors; Animals; Dutasteride; Male; Medicine, East Asian Traditional; Prostati

2021
Simultaneous HPLC determination of alfuzosin, tamsulosin and vardenafil in human plasma and pharmaceutical formulations using time programmed fluorescence detection.
    Annales pharmaceutiques francaises, 2019, Volume: 77, Issue:1

    Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Chromatography, High Pressure Liquid; Drug Co

2019
Successful reversal of isolated delayed spinal cord ischemia following endovascular abdominal aneurysm repair.
    Vascular health and risk management, 2019, Volume: 15

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Angiography, Digital Subtraction; Aortic Aneurysm, Ab

2019
Alpha-1 adrenergic antagonists induced severe rhinitis in patients with benign prostatic hyperplasia.
    Current drug safety, 2014, Volume: 9, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Cerebrospinal Fluid Rhinorrhea; Doxazosin; Humans; Ma

2014
Effects of medical therapy or surgery on prostatic and bladder resistive indices in patients with benign prostatic hyperplasia.
    Urologia internationalis, 2015, Volume: 94, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Humans; Lower Urinary Tract Symptoms; Male; Middle Ag

2015
The impact of the bladder wall thickness on the outcome of the medical treatment using alpha-blocker of BPH patients with LUTS.
    The aging male : the official journal of the International Society for the Study of the Aging Male, 2015, Volume: 18, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Humans; Lower Urinary Tract Symptoms; Male; Middle Ag

2015
The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity.
    Turkish journal of medical sciences, 2014, Volume: 44, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Autonomic Nervous System; Blood Glucose; Body Mass In

2014
Alpha blocker monotherapy versus combination therapy with antimuscarinics in men with persistent LUTS refractory to alpha-adrenergic treatment: patterns of persistence.
    The Canadian journal of urology, 2015, Volume: 22, Issue:4

    Topics: Administrative Claims, Healthcare; Adrenergic alpha-Antagonists; Aged; Benzofurans; Doxazosin; Drug

2015
[Impact of alfuzosin 10 mg once daily on quality of life in Tunisian patients with lower urinary symptoms suggestive of benign prostatic hyperplasia].
    La Tunisie medicale, 2015, Volume: 93, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Humans; Male; Middle Aged; Prospective Studies; Prost

2015
The risk of fall and fracture with the initiation of a prostate-selective α antagonist: a population based cohort study.
    BMJ (Clinical research ed.), 2015, Oct-26, Volume: 351

    Topics: Accidental Falls; Adrenergic alpha-1 Receptor Antagonists; Aged; Canada; Craniocerebral Trauma; Frac

2015
Modified corneal incisions in intraoperative floppy iris syndrome (IFIS)-prone patients.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2016, Volume: 254, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and over; Cornea; Drug Combinations; Humans;

2016
The effect of various alpha1-adrenergic receptor antagonists on pupillary dilation.
    Annals of ophthalmology (Skokie, Ill.), 2008,Spring, Volume: 40, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Doxazosin; Humans; Iris Disea

2008
Intraoperative floppy-iris syndrome associated with systemic alpha blockers.
    Journal of cataract and refractive surgery, 2008, Volume: 34, Issue:7

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Cataract Extraction; Doxazosi

2008
Safety and efficacy of a prolonged-release formulation of alfuzosin 10 mg once daily in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2009, Volume: 92, Issue:7

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Delayed-Action Preparations; Ejaculati

2009
Investigating contamination of phytotherapy products for benign prostatic hyperplasia with alpha-blockers and 5alpha-reductase inhibitors.
    The Journal of urology, 2010, Volume: 183, Issue:5

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Azasteroids; Capsules; Cholestenone 5 alpha-Redu

2010
Effects of α-blocker 'add on' treatment on blood pressure in symptomatic BPH with or without concomitant hypertension.
    Prostate cancer and prostatic diseases, 2010, Volume: 13, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Doxazosin; Drug Combina

2010
Comparison of effects of alpha receptor blockers on endothelial functions and coagulation parameters in patients with benign prostatic hyperplasia.
    Urology, 2011, Volume: 77, Issue:6

    Topics: Adrenergic alpha-Antagonists; Aged; Blood Coagulation; Blood Pressure; Brachial Artery; Doxazosin; E

2011
Alfuzosin induced thrombocytopenia after treatment for benign prostatic hyperplasia.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2010, Volume: 82, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Humans; Male; Prostatic Hyperplasia; Quinazolines; Th

2010
Prescriber monitoring for benign prostatic hyperplasia within a family medicine clinic: a comparison of medication classes.
    Journal of pharmacy practice, 2012, Volume: 25, Issue:2

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Aged; Doxazosin; Drug Therapy, Combinati

2012
The effect of alpha antagonists on pupil dynamics: implications for the diagnosis of intraoperative floppy iris syndrome.
    American journal of ophthalmology, 2012, Volume: 153, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Case-Control Studies; Cataract Extraction; Diagnostic Techn

2012
Impact of alfuzosin on sexual function in Taiwanese men with benign prostatic hyperplasia.
    The Kaohsiung journal of medical sciences, 2012, Volume: 28, Issue:8

    Topics: Aged; Drug Administration Schedule; Erectile Dysfunction; Humans; Lower Urinary Tract Symptoms; Male

2012
Reversible visual loss caused by combination therapy of alfuzosin and finasteride in a patient with uveitic glaucoma.
    Cutaneous and ocular toxicology, 2013, Volume: 32, Issue:2

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-1 Receptor Antagonists; Antihypertensive Agents; Drug

2013
The efficacy of alfuzosin treatment in patients with prostatism.
    International urology and nephrology, 2001, Volume: 33, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aged; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic

2001
Benign prostatic hyperplasia.
    Hospital medicine (London, England : 1998), 2003, Volume: 64, Issue:2

    Topics: Adrenergic alpha-Antagonists; Clinical Trials as Topic; Doxazosin; Drug Therapy, Combination; Enzyme

2003
Comparison of the relaxant effects of alfuzosin, phentolamine and sildenafil on rabbit isolated corpus cavernosum.
    BJU international, 2003, Volume: 91, Issue:9

    Topics: Adrenergic alpha-Antagonists; Animals; Erectile Dysfunction; Male; Muscle Relaxation; Penile Erectio

2003
Proceedings of the 99th meeting of the Food and Drug Administration Cardiovascular and Renal Drugs Advisory Committee. May 29th and 30th, 2003.
    Circulation, 2003, Jun-17, Volume: 107, Issue:23

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adolescent; Adult; Advisory Committees; Anti-Infective Agents;

2003
Clinical and pressure-flow changes after long-term treatment with alfuzosin SR.
    Urologia internationalis, 2003, Volume: 71, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Humans; Male; Middle Aged; Prostatic Hyperplasia; Quinazo

2003
Safety and efficacy of alfuzosin 10 mg once-daily in the treatment of lower urinary tract symptoms and clinical benign prostatic hyperplasia: a pooled analysis of three double-blind, placebo-controlled studies.
    BJU international, 2003, Volume: 92, Issue:9

    Topics: Adrenergic alpha-Antagonists; Double-Blind Method; Humans; Male; Prostatic Hyperplasia; Quinazolines

2003
Alfuzosin (uroxatral)--another alpha1-blocker for benign prostatic hyperplasia.
    The Medical letter on drugs and therapeutics, 2004, Jan-05, Volume: 46, Issue:1173

    Topics: Adrenergic alpha-Antagonists; Clinical Trials as Topic; Contraindications; Drug Interactions; Humans

2004
A current review of medical therapy for benign prostatic hyperplasia.
    The Journal of the American Osteopathic Association, 2004, Volume: 104, Issue:2 Suppl 2

    Topics: Adrenergic alpha-Antagonists; Algorithms; Azasteroids; Cholestenone 5 alpha-Reductase; Doxazosin; Dr

2004
On call. My doctor gave me a prescription for Uroxatral to treat my enlarged prostate. I tried to look up this medicine in your Harvard Medical School Guide to Men's Health, but I couldn't find it. What can you tell me about Uroxatral?
    Harvard men's health watch, 2004, Volume: 8, Issue:11

    Topics: Adrenergic beta-Antagonists; Humans; Male; Prostatic Hyperplasia; Quinazolines

2004
A comparison of four different alpha1-blockers in benign prostatic hyperplasia patients with and without diabetes.
    Scandinavian journal of urology and nephrology, 2004, Volume: 38, Issue:5

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Cohort Studies; Diabetes Mellitus; Doxazosin;

2004
Symptom deterioration during treatment and history of AUR are the strongest predictors for AUR and BPH-related surgery in men with LUTS treated with alfuzosin 10 mg once daily.
    Urology, 2005, Volume: 66, Issue:2

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Drug Administration Sch

2005
The economic impact of using alfuzosin 10 mg once daily in the management of acute urinary retention in the UK: a 6-month analysis.
    BJU international, 2005, Volume: 96, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Decision Support Techniques; Drug Costs; Emergency Treatm

2005
Early symptom improvement of benign prostatic hyperplasia (BPH) treated with once daily alfuzosin.
    The Canadian journal of urology, 2005, Volume: 12, Issue:4

    Topics: Adrenergic alpha-Antagonists; Delayed-Action Preparations; Humans; Male; Middle Aged; Prostatic Hype

2005
Effects of selective alpha-1-adrenergic receptor blockers on bladder weight.
    Urologia internationalis, 2006, Volume: 76, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Humans; Hypertrophy; Ma

2006
Are all alpha-blockers created the same?
    European urology, 2006, Volume: 49, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adult; Clinical Trials as Topic; Dizziness; Doxazosin; Humans; Male; M

2006
Dynamic variables: novel and perhaps better predictors of progression in benign prostatic hyperplasia.
    BJU international, 2006, Volume: 97, Issue:3

    Topics: Adrenergic alpha-Antagonists; Disease Progression; Humans; Male; Prostatic Hyperplasia; Quinazolines

2006
Long-term efficacy and safety of alfuzosin 10 mg once daily: a 2-year experience in 'real-life' practice.
    BJU international, 2006, Volume: 97, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aged; Ejaculation; Humans; Libido; Male; Middle Aged; Patient Satisfac

2006
Intraoperative floppy iris syndrome in a patient taking alfuzosin for benign prostatic hypertrophy.
    Eye (London, England), 2006, Volume: 20, Issue:12

    Topics: Adrenergic alpha-Antagonists; Aged, 80 and over; Cataract Extraction; Humans; Intraoperative Complic

2006
The management of acute urinary retention in France: a cross-sectional survey in 2618 men with benign prostatic hyperplasia.
    BJU international, 2006, Volume: 97, Issue:4

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Catheters, Indwelling;

2006
Toxic epidermal necrolysis caused by alfuzosin, an alpha1-adrenoceptor antagonist.
    Archives of dermatology, 2006, Volume: 142, Issue:7

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Diagnosis, Differential; Exanthema; Fever; Hu

2006
Response to daily 10 mg alfuzosin predicts acute urinary retention and benign prostatic hyperplasia related surgery in men with lower urinary tract symptoms.
    The Journal of urology, 2006, Volume: 176, Issue:3

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Aged; Drug Administration Schedule; Humans; Male; Middl

2006
Lower urinary tract symptoms (LUTS) and sexual dysfunction (SD): new targets for new combination therapies?
    European urology, 2007, Volume: 51, Issue:6

    Topics: Adrenergic alpha-Antagonists; Age Factors; Aged; Drug Therapy, Combination; Enzyme Inhibitors; Erect

2007
Incidence of intraoperative floppy iris syndrome in patients on either systemic or topical alpha1-adrenoceptor antagonist.
    American journal of ophthalmology, 2007, Volume: 143, Issue:6

    Topics: Administration, Topical; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adul

2007
Intravesical prostatic protrusion is better than prostate volume in predicting the outcome of trial without catheter in white men presenting with acute urinary retention: a prospective clinical study.
    The Journal of urology, 2007, Volume: 178, Issue:2

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Endosonography; Humans; Male;

2007
Intraoperative floppy-iris syndrome associated with alpha1-adrenoreceptors: comparison of tamsulosin and alfuzosin.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:7

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Humans; Incidence; Intr

2007
Alfuzosin-induced acute liver injury.
    The Korean journal of hepatology, 2007, Volume: 13, Issue:3

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Chemical and Drug Induced Liver Injury; Dysuria; Humans

2007
Potentiometric sensors enabling fast screening of the benign prostatic hyperplasia drug alfuzosin in pharmaceuticals, urine and serum.
    Combinatorial chemistry & high throughput screening, 2007, Volume: 10, Issue:7

    Topics: Drug Evaluation, Preclinical; Electrochemistry; Electrodes; Humans; Hydrogen-Ion Concentration; Male

2007
Comparing the therapeutic outcome of different alpha-blocker treatments for BPH in the same individuals.
    International urology and nephrology, 2008, Volume: 40, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Prazosin; Prostate

2008
Alfuzosin 10 mg once daily for treating benign prostatic hyperplasia: a 3-year experience in real-life practice.
    BJU international, 2008, Volume: 101, Issue:7

    Topics: Adrenergic alpha-Antagonists; Aged; Disease Progression; Erectile Dysfunction; Humans; Male; Nocturi

2008
[Use of terazosin and alfuzosin in the treatment of benign prostatic hypertrophy (BPH): our experience].
    Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma, 1994, Volume: 65, Issue:1-2

    Topics: Adrenergic alpha-Antagonists; Aged; Follow-Up Studies; Humans; Male; Middle Aged; Prazosin; Prostati

1994
[Alfuzosin in benign prostatic hyperplasia. A new principle is evaluated. Report of a study].
    Fortschritte der Medizin. Supplement : die Kongressinformation fur die Praxis, 1995, Volume: 166

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Humans; Male

1995
[Alpha blockers, TUS-P and TUR-P in the treatment of benign prostatic hypertrophy. A comparison using multivariate statistical analysis].
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 1995, Volume: 67, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aged; Follow-Up Studies; Humans; Male; Middle Aged; Multivariate Analy

1995
Re: Alpha-blockade in the treatment of symptomatic benign prostatic hyperplasia.
    The Journal of urology, 1996, Volume: 156, Issue:1

    Topics: Adrenergic alpha-Antagonists; Humans; Male; Prostatic Hyperplasia; Quinazolines

1996
[Drugs for prostatic adenoma].
    Soins; la revue de reference infirmiere, 1995, Issue:599

    Topics: Adrenergic alpha-Antagonists; Drug Monitoring; Enzyme Inhibitors; Finasteride; Humans; Male; Prostat

1995
Construction and validation of a short-form benign prostatic hypertrophy health-related quality-of-life questionnaire. BPH Group in General Practice.
    British journal of urology, 1997, Volume: 80, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Anxiety; Case-Control Studies; Cohort

1997
Computerized artifact detection and correction of uroflow curves: towards a more consistent quantitative assessment of maximum flow.
    European urology, 1998, Volume: 33, Issue:1

    Topics: Adrenergic alpha-Antagonists; Computer Simulation; Humans; Male; Models, Biological; Observer Variat

1998
[The treatment of patients with benign prostatic hyperplasia using the selective alpha-blocker alfuzosin].
    Terapevticheskii arkhiv, 1997, Volume: 69, Issue:10

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Drug Evaluation; Humans; Male; Middle Aged; P

1997
Clinical uroselectivity: evidence from patients treated with slow release alfuzosin for symptomatic benign prostatic obstruction.
    British journal of urology, 1998, Volume: 81, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Delayed-Action Preparations; Dose-Response Re

1998
Alfuzosin-associated dermatomyositis.
    British journal of rheumatology, 1998, Volume: 37, Issue:10

    Topics: Adrenergic alpha-Antagonists; Aged; Dermatomyositis; Humans; Magnetic Resonance Imaging; Male; Muscl

1998
One-year follow-up of 2829 patients with moderate to severe lower urinary tract symptoms treated with alfuzosin in general practice according to IPSS and a health-related quality-of-life questionnaire. BPM Group in General Practice.
    Urology, 2000, Volume: 55, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Family Practice; Follow-Up Studies; Humans; M

2000
[Prostatic benign hypertrophy: review of effectiveness, tolerance, and impact on quality of life of prolonged treatment with alfuzosin].
    Actas urologicas espanolas, 2000, Volume: 24, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aged; Humans; Male; Prostatic Hyperplasia; Quality of Life; Quinazolin

2000
Evaluating adverse cardiovascular effects of drug treatment for benign prostatic hyperplasia (BPH): methodological considerations.
    Journal of clinical epidemiology, 2001, Volume: 54, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Adult; Aged; Bias; Cardiovascular Diseas

2001
Efficacy and tolerability of drugs for treatment of benign prostatic hyperplasia.
    International urology and nephrology, 2001, Volume: 32, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aged; Doxazosin; Enzyme Inhibitors; Finasteride; Humans; Male; Middle

2001
Long-term risk of re-treatment of patients using alpha-blockers for lower urinary tract symptoms.
    The Journal of urology, 2002, Volume: 167, Issue:4

    Topics: Adrenergic beta-Antagonists; Follow-Up Studies; Humans; Male; Middle Aged; Prazosin; Prostatic Hyper

2002
[Alfuzosin. A new selective alpha 1 receptor antagonist for symptomatic medical treatment of benign prostatic hypertrophy prior to surgery].
    Ugeskrift for laeger, 1992, Feb-03, Volume: 154, Issue:6

    Topics: Adrenergic alpha-Antagonists; Humans; Male; Premedication; Preoperative Care; Prostatectomy; Prostat

1992
[Comparison of selective alpha-1 blockades for alpha-receptors in human hypertrophied prostatic adenomas].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1992, Volume: 83, Issue:3

    Topics: Adenoma; Adrenergic alpha-Antagonists; Aged; Humans; Male; Piperazines; Prazosin; Prostatic Hyperpla

1992
Alfuzosin for benign prostatic hypertrophy.
    Lancet (London, England), 1991, Jul-20, Volume: 338, Issue:8760

    Topics: Adrenergic alpha-Antagonists; Drug Administration Schedule; Humans; Male; Prazosin; Prostatic Hyperp

1991
Alfuzosin for benign prostatic hypertrophy.
    Lancet (London, England), 1991, Oct-12, Volume: 338, Issue:8772

    Topics: Adrenergic alpha-Antagonists; Humans; Male; Prostatic Hyperplasia; Quinazolines

1991