Page last updated: 2024-08-23

alfentanil and Respiratory Insufficiency

alfentanil has been researched along with Respiratory Insufficiency in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19904 (15.38)18.7374
1990's5 (19.23)18.2507
2000's7 (26.92)29.6817
2010's8 (30.77)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Algera, H; Cavalla, D; Dahan, A; Evans, S; Horrigan, JP; Kiernan, B; McMorn, A; Niesters, M; Olofsen, E; Roozekrans, M; Sarton, E; Snape, M; van der Schrier, R; van Velzen, M1
Chen, ZJ; Li, JY; Wang, JF; Xu, L; Yu, L; Zhang, L1
Liou, JY; Mandell, MS; Teng, WN; Ting, CK; Tsou, MY1
Dahan, A; Hay, J; McLeod, JF; Okkerse, P; Roozekrans, M; van der Schrier, R1
Brock-Utne, JG; Drover, DR; He, L; Leng, JC; Leng, T; Silva, RA1
Boom, M; Dahan, A; Mooren, R; Olofsen, E; Roozekrans, M; van der Schrier, R1
Carson, JR; Codd, EE; Colburn, RW; Dax, SL; Flores, CM; Gallantine, EL; Meert, TF; Molino, L; Pullan, S; Razler, CM; Stone, DJ; Van Besien, CR; Wade, PR; Zhang, SP1
Fantegrossi, WE; Galuska, CM; Ko, MC; Prinssen, EP; Wichmann, J; Woods, JH1
Biros, MH; Gray, RO; Miner, JR; Stephens, D1
Angst, MS; Bradshaw, MH; Felden, L; Geisslinger, G; Greer, JJ; Johnson, S; Lötsch, J; Oertel, BG; Schmidt, H; Tran, PV; Varney, MA1
Dreher, M; Ekkernkamp, E; Kabitz, HJ; Storre, JH; Windisch, W1
Lee, P; Mathur, PN1
Carmi, U; Fruchter, O; Kramer, MR; Rosengarten, D; Zemtzov, D1
Bouillon, T; Bruhn, J; Hoeft, A; Roepcke, H1
Bouillon, T; Garstka, G; Hoeft, A; Schwilden, H; Shafer, S; Stafforst, D1
Aubert, D; Bertschy, C; Brix, M; Brugie, H; Lassauge, F1
Geisslinger, G; Lötsch, J; Oertel, BG; Schmidt, R; Schneider, A1
Flynn, PJ; Lalor, JM; Sebel, RS; Simpson, BA1
Sandin, RH; Sternlo, JE1
Chang, KJ; McNutt, RW; Su, YF1
Batson, MA; Csontos, E; Longmire, S1
Bahr, M; Nikki, P; Paloheimo, MP1
Johnson, DL; Krane, BD; Kreutz, JM; Mazuzan, JE1
Hull, CJ1
Eisele, JH; Golub, MS; Kuhnert, BR1

Reviews

2 review(s) available for alfentanil and Respiratory Insufficiency

ArticleYear
Recurrent respiratory depression after total intravenous anaesthesia with propofol and alfentanil.
    Anaesthesia, 1998, Volume: 53, Issue:4

    Topics: Adult; Alfentanil; Anesthetics, Combined; Anesthetics, Intravenous; Female; Humans; Male; Middle Aged; Propofol; Recurrence; Respiratory Insufficiency

1998
Alfentanil and delayed respiratory depression: case studies and review.
    Anesthesia and analgesia, 1990, Volume: 70, Issue:5

    Topics: Adult; Alfentanil; Anesthesia Recovery Period; Female; Humans; Male; Middle Aged; Naloxone; Postoperative Complications; Respiratory Insufficiency

1990

Trials

8 trial(s) available for alfentanil and Respiratory Insufficiency

ArticleYear
Respiratory Effects of the Atypical Tricyclic Antidepressant Tianeptine in Human Models of Opioid-induced Respiratory Depression.
    Anesthesiology, 2022, 10-01, Volume: 137, Issue:4

    Topics: Alfentanil; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Carbon Dioxide; Double-Blind Method; Female; Humans; Male; Remifentanil; Respiratory Insufficiency; Respiratory System Agents; Thiazepines

2022
Effectiveness of remimazolam besylate combined with alfentanil for fiberoptic bronchoscopy with preserved spontaneous breathing: a prospective, randomized, controlled clinical trial.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:13

    Topics: Alfentanil; Benzodiazepines; Bronchoscopy; Humans; Hypnotics and Sedatives; Hypotension; Propofol; Prospective Studies; Respiratory Insufficiency

2023
Two studies on reversal of opioid-induced respiratory depression by BK-channel blocker GAL021 in human volunteers.
    Anesthesiology, 2014, Volume: 121, Issue:3

    Topics: Adolescent; Adult; Alfentanil; Analgesia; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Doxapram; Healthy Volunteers; Hemodynamics; Humans; Large-Conductance Calcium-Activated Potassium Channels; Male; Middle Aged; Potassium Channel Blockers; Respiratory Insufficiency; Triazines

2014
Doxapram-mediated Increase in Cardiac Output Reduces Opioid Plasma Concentrations: A Pharmacokinetic/Pharmacodynamic-Pharmacokinetic/Pharmacodynamic Modeling Study in Healthy Volunteers.
    Clinical pharmacology and therapeutics, 2017, Volume: 102, Issue:1

    Topics: Adult; Alfentanil; Analgesics; Analgesics, Opioid; Blood Pressure; Cardiac Output; Central Nervous System Stimulants; Doxapram; Healthy Volunteers; Humans; Male; Metabolic Clearance Rate; Respiratory Insufficiency; Respiratory System Agents; Treatment Outcome

2017
Randomized clinical trial of propofol with and without alfentanil for deep procedural sedation in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:9

    Topics: Adult; Alfentanil; Anesthetics, Intravenous; Deep Sedation; Drug Combinations; Emergency Medical Services; Humans; Oxygen; Oxygen Inhalation Therapy; Pain; Propofol; Respiratory Insufficiency; Treatment Outcome

2009
Selective antagonism of opioid-induced ventilatory depression by an ampakine molecule in humans without loss of opioid analgesia.
    Clinical pharmacology and therapeutics, 2010, Volume: 87, Issue:2

    Topics: Administration, Oral; Adult; Alfentanil; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Humans; Hypercapnia; Isoxazoles; Male; Naloxone; Narcotic Antagonists; Oxygen; Pain; Respiratory Insufficiency; Young Adult

2010
Propofol safety in bronchoscopy: prospective randomized trial using transcutaneous carbon dioxide tension monitoring.
    Respiration; international review of thoracic diseases, 2011, Volume: 82, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alfentanil; Anesthesia Recovery Period; Anesthetics, Intravenous; Blood Gas Monitoring, Transcutaneous; Bronchoscopy; Carbon Dioxide; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Oxygen; Propofol; Prospective Studies; Respiratory Insufficiency; Young Adult

2011
The mu-opioid receptor gene polymorphism 118A>G depletes alfentanil-induced analgesia and protects against respiratory depression in homozygous carriers.
    Pharmacogenetics and genomics, 2006, Volume: 16, Issue:9

    Topics: Adult; Alfentanil; Analgesia; Analgesics; Carbon Dioxide; Dose-Response Relationship, Drug; Electric Stimulation; Female; Forced Expiratory Volume; Genotype; Heterozygote; Homozygote; Humans; Infusion Pumps; Male; Pain; Polymorphism, Genetic; Receptors, Opioid, mu; Respiration; Respiratory Insufficiency; Treatment Outcome

2006

Other Studies

16 other study(ies) available for alfentanil and Respiratory Insufficiency

ArticleYear
Adaptation of non-linear mixed amount with zero amount response surface model for analysis of concentration-dependent synergism and safety with midazolam, alfentanil, and propofol sedation.
    British journal of anaesthesia, 2018, Volume: 120, Issue:6

    Topics: Adult; Aged; Alfentanil; Conscious Sedation; Drug Administration Schedule; Drug Combinations; Drug Synergism; Endoscopy, Gastrointestinal; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Models, Biological; Propofol; Respiratory Insufficiency

2018
Risk factors for respiratory depression in patients undergoing retrobulbar block for vitreoretinal surgery.
    Ophthalmic surgery, lasers & imaging retina, 2015, Volume: 46, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alfentanil; Anesthesia, Conduction; Anesthetics, Combined; Anesthetics, Intravenous; Conscious Sedation; Female; Fentanyl; Humans; Male; Midazolam; Middle Aged; Nerve Block; Orbit; Propofol; Prospective Studies; Respiratory Insufficiency; Risk Factors; Vitreoretinal Surgery; Young Adult

2015
JNJ-20788560 [9-(8-azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic acid diethylamide], a selective delta opioid receptor agonist, is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic toler
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:1

    Topics: Alfentanil; Analgesics, Opioid; Animals; Azabicyclo Compounds; Cricetinae; Drug Tolerance; Gastrointestinal Motility; Guanosine 5'-O-(3-Thiotriphosphate); Hot Temperature; Hyperalgesia; Irritants; Male; Mice; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, delta; Respiratory Insufficiency; Seizures; Self Administration; Stomach Ulcer; Substance Withdrawal Syndrome; Substance-Related Disorders; Xanthenes; Zymosan

2009
Behavioral effects of a synthetic agonist selective for nociceptin/orphanin FQ peptide receptors in monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:9

    Topics: Alfentanil; Analgesics, Opioid; Animals; Behavior, Animal; Benzimidazoles; Capsaicin; Central Nervous System Agents; Dose-Response Relationship, Drug; Female; Hot Temperature; Imidazoles; Macaca mulatta; Male; Naltrexone; Narcotic Antagonists; Nociceptin Receptor; Pain; Piperidines; Pruritus; Receptors, Opioid; Receptors, Opioid, mu; Reinforcement, Psychology; Respiratory Insufficiency; Spiro Compounds

2009
Sedation during flexible bronchoscopy in patients with pre-existing respiratory failure: Midazolam versus Midazolam plus Alfentanil.
    Respiration; international review of thoracic diseases, 2010, Volume: 79, Issue:4

    Topics: Adult; Aged; Alfentanil; Anesthesia Recovery Period; Anesthetics, Intravenous; Blood Gas Monitoring, Transcutaneous; Bronchoscopy; Carbon Dioxide; Female; Heart Rate; Humans; Male; Midazolam; Middle Aged; Oxygen; Respiratory Insufficiency

2010
Safe to sedate for bronchoscopy despite respiratory failure.
    Respiration; international review of thoracic diseases, 2010, Volume: 79, Issue:4

    Topics: Alfentanil; Anesthetics, Intravenous; Bronchoscopy; Humans; Midazolam; Respiratory Insufficiency

2010
Opioid-induced respiratory depression is associated with increased tidal volume variability.
    European journal of anaesthesiology, 2003, Volume: 20, Issue:2

    Topics: Adult; Aged; Alfentanil; Analgesics, Opioid; Analysis of Variance; Female; Humans; Infusions, Intravenous; Laryngeal Masks; Male; Middle Aged; Pirinitramide; Respiratory Insufficiency; Tidal Volume; Time Factors

2003
Piritramide and alfentanil display similar respiratory depressant potency.
    Acta anaesthesiologica Scandinavica, 2003, Volume: 47, Issue:10

    Topics: Adult; Aged; Alfentanil; Analgesics, Opioid; Carbon Dioxide; Depression, Chemical; Female; Humans; Male; Middle Aged; Pirinitramide; Respiratory Insufficiency; Retrospective Studies

2003
[Specific features of anesthesia for primary surgery in children with facial and palatal clefts: retrospective study in 93 children at the Besançon University Hospital].
    Revue de stomatologie et de chirurgie maxillo-faciale, 2006, Volume: 107, Issue:2

    Topics: Alfentanil; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Loss, Surgical; Cleft Lip; Cleft Palate; Female; Halothane; Humans; Infant; Isoflurane; Laryngismus; Male; Maxilla; Methyl Ethers; Pierre Robin Syndrome; Postoperative Complications; Postoperative Nausea and Vomiting; Respiratory Insufficiency; Retrospective Studies; Sevoflurane; Sufentanil

2006
Respiratory depression after alfentanil infusion.
    British medical journal (Clinical research ed.), 1984, Dec-08, Volume: 289, Issue:6458

    Topics: Aged; Alfentanil; Analgesics, Opioid; Female; Fentanyl; Humans; Infusions, Parenteral; Male; Middle Aged; Respiratory Insufficiency

1984
Delta-opioid ligands reverse alfentanil-induced respiratory depression but not antinociception.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:3

    Topics: Alfentanil; Analgesics, Opioid; Animals; Benzamides; Hypercapnia; Ligands; Male; Naltrexone; Narcotic Antagonists; Narcotics; Oligopeptides; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration; Respiratory Insufficiency; Somatostatin

1998
Alfentanil for urgent caesarean section in a patient with severe mitral stenosis and pulmonary hypertension.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:6

    Topics: Adult; Alfentanil; Anesthesia, Intravenous; Anesthesia, Obstetrical; Carbon Dioxide; Cesarean Section; Female; Fetal Blood; Humans; Hypertension, Pulmonary; Infant, Newborn; Male; Mitral Valve Stenosis; Oxygen; Pregnancy; Pregnancy Complications, Cardiovascular; Respiratory Insufficiency

1990
Comparison of non-invasive respiratory and arterial blood gas analysis. A recovery room study on acute respiratory depression.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1990, Volume: 203

    Topics: Aged; Aged, 80 and over; Alfentanil; Analgesia; Anesthesia, Local; Arteries; Blood Gas Analysis; Carbon Dioxide; Cataract Extraction; Female; Humans; Male; Middle Aged; Oxygen; Pulmonary Gas Exchange; Respiration; Respiratory Insufficiency

1990
Alfentanil anesthesia in gall bladder surgery.
    Acta anaesthesiologica Scandinavica, 1986, Volume: 30, Issue:8

    Topics: Alfentanil; Anesthesia, Intravenous; Fentanyl; Humans; Respiratory Insufficiency

1986
Disposition of intrapartum narcotic analgesics in monkeys.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:7

    Topics: Alfentanil; Anesthesia, Intravenous; Anesthesia, Obstetrical; Animals; Female; Fentanyl; Fetal Blood; Labor, Obstetric; Macaca mulatta; Maternal-Fetal Exchange; Meperidine; Pregnancy; Protein Binding; Respiratory Insufficiency

1988
Respiratory depression after alfentanil infusion.
    British medical journal (Clinical research ed.), 1985, Jan-26, Volume: 290, Issue:6464

    Topics: Adjuvants, Anesthesia; Alfentanil; Fentanyl; Humans; Respiratory Insufficiency

1985