Page last updated: 2024-10-22

alexidine and Pancreatic Neoplasms

alexidine has been researched along with Pancreatic Neoplasms in 1 studies

alexidine: until June 1975 was mistakenly treated as synonym for chlorhexidine; RN given refers to parent cpd
alexidine : An amphipathic bisbiguanide with a structure consisting of two (2-ethylhexyl)guanide units linked by a hexamethylene bridge.

Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Research Excerpts

ExcerptRelevanceReference
" Alexidine Dihydrochloride (AD), an orally bioavailable bis-biguanide compound, is an apoptosis stimulating reagent."1.56Repurposing of Alexidine Dihydrochloride as an Apoptosis Initiator and Cell Cycle Inhibitor in Human Pancreatic Cancer. ( Aydemir, E; Bayrak, OF; Kasikci, E; Sahin, F; Yogurtcu, BM, 2020)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Kasikci, E1
Aydemir, E1
Yogurtcu, BM1
Sahin, F1
Bayrak, OF1

Other Studies

1 other study available for alexidine and Pancreatic Neoplasms

ArticleYear
Repurposing of Alexidine Dihydrochloride as an Apoptosis Initiator and Cell Cycle Inhibitor in Human Pancreatic Cancer.
    Anti-cancer agents in medicinal chemistry, 2020, Volume: 20, Issue:16

    Topics: Antineoplastic Agents; Apoptosis; Biguanides; Cell Cycle; Cell Line; Dose-Response Relationship, Dru

2020