Page last updated: 2024-10-22

alexidine and Dental Plaque

alexidine has been researched along with Dental Plaque in 7 studies

alexidine: until June 1975 was mistakenly treated as synonym for chlorhexidine; RN given refers to parent cpd
alexidine : An amphipathic bisbiguanide with a structure consisting of two (2-ethylhexyl)guanide units linked by a hexamethylene bridge.

Dental Plaque: A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.

Research Excerpts

ExcerptRelevanceReference
"The primary purpose of this study was to determine the safety and effectiveness of alexidine in the control of plaque and gingivitis in humans."9.04Effects of an alexidine mouthwash on dental plaque and gingivitis in humans over a six-month period. ( Finn, SB; Jamison, HC; Weatherford, TW, 1977)
"The primary purpose of this study was to determine the safety and effectiveness of alexidine in the control of plaque and gingivitis in humans."5.04Effects of an alexidine mouthwash on dental plaque and gingivitis in humans over a six-month period. ( Finn, SB; Jamison, HC; Weatherford, TW, 1977)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Warner, VD1
Lynch, DM1
Kim, KH1
Grunewald, GL1
Moran, J1
Addy, M2
Roberts, WR1
Weatherford, TW1
Finn, SB1
Jamison, HC1
Carlson, HC1
Porter, K1
Alms, TH1
Shern, RJ1
Rapani, E1

Trials

2 trials available for alexidine and Dental Plaque

ArticleYear
Comparison of the bisbiguanide antiseptics alexidine and chlorhexidine. I. Effect on plaque accumulation and salivary bacteria.
    Journal of clinical periodontology, 1981, Volume: 8, Issue:3

    Topics: Adult; Bacteria; Biguanides; Chlorhexidine; Dental Plaque; Humans; Male; Mouthwashes; Saliva; Time F

1981
Effects of an alexidine mouthwash on dental plaque and gingivitis in humans over a six-month period.
    Journal of the American Dental Association (1939), 1977, Volume: 94, Issue:3

    Topics: Adolescent; Adult; Aged; Biguanides; Dental Plaque; Drug Evaluation; Female; Gingivitis; Humans; Mal

1977

Other Studies

5 other studies available for alexidine and Dental Plaque

ArticleYear
Quantitative structure-activity relationships for biguanides, carbamimidates, and bisbiguanides as inhibitors of Streptococcus mutans No. 6715.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:4

    Topics: Biguanides; Dental Plaque; Imides; Microbial Sensitivity Tests; Models, Biological; Solubility; Stre

1979
The effect of surface adsorption and staining reactions on the antimicrobial properties of some cationic antiseptic mouthwashes.
    Journal of periodontology, 1984, Volume: 55, Issue:5

    Topics: Adsorption; Anti-Infective Agents, Local; Bacteria; Biguanides; Cetylpyridinium; Chlorhexidine; Dent

1984
The effect of an alexidine mouthwash on dental plaque and gingivitis.
    Journal of periodontology, 1977, Volume: 48, Issue:4

    Topics: Adolescent; Adult; Aged; Biguanides; Color; Dental Plaque; Gingivitis; Humans; Middle Aged; Mouthwas

1977
Effects of various organic compounds and fluoride on dental plaque and caries in rats.
    Caries research, 1988, Volume: 22, Issue:3

    Topics: Actinomyces; Animals; Biguanides; Cariostatic Agents; Cations; Dental Caries; Dental Plaque; Female;

1988
[Mouthrinses in the prevention of dental caries].
    Rivista di odontostomatologia e implantoprotesi, 1985, Issue:2

    Topics: Biguanides; Chlorhexidine; Dental Caries; Dental Plaque; Humans; Mouthwashes

1985