Page last updated: 2024-10-22

alendronate and Ulcer

alendronate has been researched along with Ulcer in 16 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.

Research Excerpts

ExcerptRelevanceReference
"Alendronate is commonly used in the treatment of osteoporosis and other bone diseases."8.88Laryngeal ulceration and hemoptysis secondary to inadvertent alendronate overdose: case report and review of the literature. ( Bee, J; Hanna, J; Sataloff, RT, 2012)
"We describe three patients who had severe esophagitis shortly after starting to take alendronate and also analyze adverse esophageal effects reported to Merck, the manufacturer, through postmarketing surveillance."8.79Esophagitis associated with the use of alendronate. ( Daifotis, A; de Groen, PC; Freedholm, D; Hirsch, LJ; Lubbe, DF; Pinkas, H; Pryor-Tillotson, S; Seleznick, MJ; Stephenson, W; Wang, KK, 1996)
"We present a case of esophageal ulcerations caused by alendronate (Fosamax), a recently marketed medication."8.79A new probable increasing cause of esophageal ulceration: alendronate. ( Colina, RE; Kikendall, JW; Smith, M; Wong, RK, 1997)
" We used health registers to identify predictors of new major osteoporotic fractures in patients adhering to alendronate."7.79Characteristics of patients who suffer major osteoporotic fractures despite adhering to alendronate treatment: a National Prescription registry study. ( Abrahamsen, B; Eastell, R; Eiken, PA; Rubin, KH, 2013)
"Alendronate is commonly used in the treatment of osteoporosis and other bone diseases."4.88Laryngeal ulceration and hemoptysis secondary to inadvertent alendronate overdose: case report and review of the literature. ( Bee, J; Hanna, J; Sataloff, RT, 2012)
"We describe three patients who had severe esophagitis shortly after starting to take alendronate and also analyze adverse esophageal effects reported to Merck, the manufacturer, through postmarketing surveillance."4.79Esophagitis associated with the use of alendronate. ( Daifotis, A; de Groen, PC; Freedholm, D; Hirsch, LJ; Lubbe, DF; Pinkas, H; Pryor-Tillotson, S; Seleznick, MJ; Stephenson, W; Wang, KK, 1996)
"We present a case of esophageal ulcerations caused by alendronate (Fosamax), a recently marketed medication."4.79A new probable increasing cause of esophageal ulceration: alendronate. ( Colina, RE; Kikendall, JW; Smith, M; Wong, RK, 1997)
" We used health registers to identify predictors of new major osteoporotic fractures in patients adhering to alendronate."3.79Characteristics of patients who suffer major osteoporotic fractures despite adhering to alendronate treatment: a National Prescription registry study. ( Abrahamsen, B; Eastell, R; Eiken, PA; Rubin, KH, 2013)
"Ingestion of alendronate sodium (Fosamax) by osteoporotic patients can be associated with esophagitis and esophageal ulcer."3.70Alendronate-associated esophageal injury: pathologic and endoscopic features. ( Abraham, SC; Cruz-Correa, M; Lee, LA; Wu, TT; Yardley, JH, 1999)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (68.75)18.2507
2000's1 (6.25)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sakaida, H1
Yuasa, H1
Fukutome, K1
Takeuchi, K1
Ueda, K1
Muto, M1
Chiba, T1
Abrahamsen, B1
Rubin, KH1
Eiken, PA1
Eastell, R1
Hanna, J1
Bee, J1
Sataloff, RT1
Terashima, T1
Hiramatsu, K1
Shimatani, A1
Matsuda, M1
Ogino, H1
Satomura, Y1
Noda, Y1
Maconi, G1
Bianchi Porro, G1
Abdelmalek, MF1
Douglas, DD1
de Groen, PC1
Lubbe, DF1
Hirsch, LJ2
Daifotis, A1
Stephenson, W1
Freedholm, D1
Pryor-Tillotson, S1
Seleznick, MJ1
Pinkas, H1
Wang, KK1
Castell, DO1
Liberman, UI1
Sorrentino, D1
Trevisi, A1
Bernardis, V1
DeBiase, F1
Labombarda, A1
Bartoli, E1
Colina, RE1
Smith, M1
Kikendall, JW1
Wong, RK1
Tursi, A1
Cuoco, L1
Cammarota, G1
Papa, A1
De Vitis, I1
Fedeli, G1
Gasbarrini, G1
Kaye, PS1
Abraham, SC1
Cruz-Correa, M1
Lee, LA1
Yardley, JH1
Wu, TT1

Reviews

3 reviews available for alendronate and Ulcer

ArticleYear
Laryngeal ulceration and hemoptysis secondary to inadvertent alendronate overdose: case report and review of the literature.
    Ear, nose, & throat journal, 2012, Volume: 91, Issue:11

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Drug Overdose; Hemoptysis; Humans; Laryngeal Di

2012
Esophagitis associated with the use of alendronate.
    The New England journal of medicine, 1996, Oct-03, Volume: 335, Issue:14

    Topics: Aged; Aged, 80 and over; Alendronate; Diphosphonates; Esophagitis; Female; Humans; Osteoporosis, Pos

1996
A new probable increasing cause of esophageal ulceration: alendronate.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:4

    Topics: Adult; Alendronate; Biopsy; Esophageal Diseases; Esophagogastric Junction; Esophagoscopy; Female; Hu

1997

Trials

1 trial available for alendronate and Ulcer

ArticleYear
Esophagitis and alendronate.
    The New England journal of medicine, 1996, Oct-03, Volume: 335, Issue:14

    Topics: Alendronate; Diphosphonates; Esophageal Diseases; Esophagitis; Female; Humans; Osteoporosis, Postmen

1996

Other Studies

12 other studies available for alendronate and Ulcer

ArticleYear
Pharyngolaryngeal ulcers associated with the improper use of alendronate.
    Auris, nasus, larynx, 2017, Volume: 44, Issue:6

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Female; Humans; Laryngeal Diseases; Osteoporosi

2017
A case of esophageal ulcer caused by alendronate sodium tablets.
    Gastrointestinal endoscopy, 2011, Volume: 73, Issue:5

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Diagnosis, Differential; Endoscopy, Gastrointes

2011
Characteristics of patients who suffer major osteoporotic fractures despite adhering to alendronate treatment: a National Prescription registry study.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2013, Volume: 24, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Comorbid

2013
An esophageal ulcer mimicking advanced esophageal cancer in a patient on alendronate sodium treatment for osteoporosis.
    Endoscopy, 2006, Volume: 38 Suppl 2

    Topics: Alendronate; Bone Density Conservation Agents; Diagnosis, Differential; Esophageal Diseases; Esophag

2006
Multiple ulcerative esophagitis caused by alendronate.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:10

    Topics: Alendronate; Diphosphonates; Esophagitis; Female; Humans; Middle Aged; Ulcer

1995
Alendronate-induced ulcerative esophagitis.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:6

    Topics: Aged; Alendronate; Diphosphonates; Drug Interactions; Esophagitis; Humans; Male; Ulcer

1996
Postmarketing surveillance indicates need for better education of patients taking alendronate.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, May-01, Volume: 53, Issue:9

    Topics: Alendronate; Diphosphonates; Esophageal Diseases; Esophagitis; Humans; Patient Education as Topic; P

1996
"Pill esophagitis"--the case of alendronate.
    The New England journal of medicine, 1996, Oct-03, Volume: 335, Issue:14

    Topics: Alendronate; Diphosphonates; Esophagitis; Female; Humans; Osteoporosis, Postmenopausal; Ulcer

1996
Esophageal ulceration due to alendronate.
    Endoscopy, 1996, Volume: 28, Issue:6

    Topics: Adult; Alendronate; Esophageal Diseases; Humans; Male; Osteoporosis; Ulcer

1996
Ulcerative oesophagitis due to alendronate.
    Italian journal of gastroenterology and hepatology, 1997, Volume: 29, Issue:5

    Topics: Aged; Alendronate; Esophagitis; Female; Humans; Ulcer

1997
Gastric hemorrhage and ulceration in hiatal hernia sac associated with alendronate.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:5

    Topics: Aged; Aged, 80 and over; Alendronate; Esophageal Diseases; Female; Gastrointestinal Hemorrhage; Hern

1999
Alendronate-associated esophageal injury: pathologic and endoscopic features.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 1999, Volume: 12, Issue:12

    Topics: Aged; Aged, 80 and over; Alendronate; Esophageal Diseases; Esophagitis; Esophagoscopy; Esophagus; Fe

1999