alendronate has been researched along with Tibial Fractures in 7 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
Tibial Fractures: Fractures of the TIBIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Long-term use has resulted in unexpected subtrochanteric fractures in some elderly patients." | 5.37 | Alendronate-associated ulnar and tibial fractures: a case report. ( Kumar, VP; Tang, ZH, 2011) |
| " The fractures were associated with 6 years of oral alendronate treatment immediately followed by subcutaneous denosumab therapy and later teriparatide therapy for osteoporosis." | 5.01 | Antiresorptive-associated spontaneous fractures of both tibiae, followed by an atypical femur fracture during the sequential treatment with alendronate, denosumab then teriparatide. ( Poole, K; Sano, H; Tan, J, 2019) |
| "However, a limited amount of bone resorption is required for bisphosphonates to exert an effect." | 1.42 | Anti-RANKL treatment improves screw fixation in cancellous bone in rats. ( Aspenberg, P; Bernhardsson, M; Sandberg, O, 2015) |
| " Long-term use has resulted in unexpected subtrochanteric fractures in some elderly patients." | 1.37 | Alendronate-associated ulnar and tibial fractures: a case report. ( Kumar, VP; Tang, ZH, 2011) |
| " Concerns have been raised about potential oversuppression of bone turnover and the development of atypical skeletal fragility associated with long-term use of bisphosphonates." | 1.36 | Atypical insufficiency fracture of the tibia associated with long-term bisphosphonate therapy. ( Breglia, MD; Carter, JD, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tan, J | 1 |
| Sano, H | 1 |
| Poole, K | 1 |
| Aspenberg, P | 2 |
| Bernhardsson, M | 1 |
| Sandberg, O | 1 |
| Breglia, MD | 1 |
| Carter, JD | 1 |
| Tang, ZH | 1 |
| Kumar, VP | 1 |
| van der Poest Clement, E | 1 |
| van Engeland, M | 1 |
| Adèr, H | 1 |
| Roos, JC | 1 |
| Patka, P | 1 |
| Lips, P | 1 |
| Nakamura, T | 1 |
1 review available for alendronate and Tibial Fractures
| Article | Year |
|---|---|
Antiresorptive-associated spontaneous fractures of both tibiae, followed by an atypical femur fracture during the sequential treatment with alendronate, denosumab then teriparatide.
Topics: Absorptiometry, Photon; Adult; Alendronate; Bone Density; Denosumab; Dose-Response Relationship, Dru | 2019 |
1 trial available for alendronate and Tibial Fractures
| Article | Year |
|---|---|
Alendronate in the prevention of bone loss after a fracture of the lower leg.
Topics: Adult; Alendronate; Bone Resorption; Double-Blind Method; Female; Humans; Male; Middle Aged; Prospec | 2002 |
5 other studies available for alendronate and Tibial Fractures
| Article | Year |
|---|---|
Alendronate-eluting polyglucose-lignol composite (POGLICO): a new biomaterial for fracture fixating implants.
Topics: Alendronate; Animals; Bone Density Conservation Agents; Bone Screws; Coated Materials, Biocompatible | 2014 |
Anti-RANKL treatment improves screw fixation in cancellous bone in rats.
Topics: Alendronate; Animals; Bone Density Conservation Agents; Bone Resorption; Diphosphonates; Fracture He | 2015 |
Atypical insufficiency fracture of the tibia associated with long-term bisphosphonate therapy.
Topics: Adrenal Cortex Hormones; Alendronate; Antirheumatic Agents; Arthritis, Rheumatoid; Diphosphonates; F | 2010 |
Alendronate-associated ulnar and tibial fractures: a case report.
Topics: Aged; Alendronate; Bone Density Conservation Agents; Female; Humans; Radiography; Tibial Fractures; | 2011 |
[Fragility fracture and its control].
Topics: Accidental Falls; Aged; Alendronate; Female; Fractures, Spontaneous; Hip Fractures; Humans; Male; Os | 2003 |