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alendronate and Root Resorption

alendronate has been researched along with Root Resorption in 14 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Root Resorption: Resorption in which cementum or dentin is lost from the root of a tooth owing to cementoclastic or osteoclastic activity in conditions such as trauma of occlusion or neoplasms. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" Also, we estimated the optimal dosage of zoledronate in root treatment of the rat model for a maximum effect of zoledronate."5.42Could zoledronic acid prevent root resorption in replanted rat molar? ( Choi, SC; Kim, EC; Kim, KC; Kim, MS; Kwon, YD; Yoo, JE, 2015)
"Alendronate (ALN) is a third generation bisphosphonate with demonstrated osteoclast inhibitory activity that may slow down the resorptive process after severe traumatic injuries."5.31Effect of topical alendronate on root resorption of dried replanted dog teeth. ( Bryson, EC; Caplan, D; Levin, L; Trope, M, 2001)
"Alendronate cytotoxicity (10(-3) to 10(-9) mol/L) in human periodontal ligament fibroblasts, human osteogenic sarcoma cells, and murine osteoclastic precursors (RAW 264."3.81Effects of alendronate on osteoclast formation and activity in vitro. ( Geurtsen, W; Leyhausen, G; Martins, CA; Volk, J, 2015)
"The purpose of this study was to evaluate the potential usefulness of two bisphosphonates (BPs) (etidronate and zoledronate), compared with that of alendronate, which is a well-known drug for delayed replantation, in decreasing or preventing inflammatory root resorption and replacement root resorption in replanted teeth."3.76The effects of topical application of bisphosphonates on replanted rat molars. ( Choi, SC; Kim, GT; Kim, KC; Kwon, YD, 2010)
"Alendronate is a known inhibitor of root resorption and the development of alendronate paste would enhance its utilization as intracanal medication."3.75Biocompatibility evaluation of alendronate paste in rat's subcutaneous tissue. ( Capaldi, ML; Castilho, LR; de Moraes, IG; Mori, GG; Nunes, DC; Poi, WR, 2009)
"Our previous study showed that topical alendronate, an inhibitor of bone resorption, reduces root resorption and ankylosis for 21 d after replantation of rat teeth."3.74Long-term effects of local pretreatment with alendronate on healing of replanted rat teeth. ( Kawasaki, K; Komatsu, K; Nifuji, A; Oida, S; Shibata, T; Shimada, A; Shimoda, S, 2008)
" Also, we estimated the optimal dosage of zoledronate in root treatment of the rat model for a maximum effect of zoledronate."1.42Could zoledronic acid prevent root resorption in replanted rat molar? ( Choi, SC; Kim, EC; Kim, KC; Kim, MS; Kwon, YD; Yoo, JE, 2015)
"Atorvastatin (ATV) has bone anabolic properties, and alendronate (ALD) is an important antiresorptive drug."1.40Low-dose combination of alendronate and atorvastatin reduces ligature-induced alveolar bone loss in rats. ( Alencar, NM; Benevides, NM; Goes, P; Lima, V; Melo, IM; Ribeiro, RA; Silva, LM, 2014)
"Alendronate (ALN) is a third generation bisphosphonate with demonstrated osteoclast inhibitory activity that may slow down the resorptive process after severe traumatic injuries."1.31Effect of topical alendronate on root resorption of dried replanted dog teeth. ( Bryson, EC; Caplan, D; Levin, L; Trope, M, 2001)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's6 (42.86)29.6817
2010's7 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, M1
Kim, S1
Ko, H1
Song, M1
Goes, P1
Melo, IM1
Silva, LM1
Benevides, NM1
Alencar, NM1
Ribeiro, RA1
Lima, V1
Rothbarth, CP1
Bradaschia-Correa, V1
Ferreira, LB1
Arana-Chavez, VE1
Martins, CA1
Leyhausen, G1
Volk, J1
Geurtsen, W1
Yoo, JE1
Kim, MS1
Kwon, YD2
Kim, EC1
Kim, KC2
Choi, SC2
Mori, GG2
de Moraes, IG2
Nunes, DC1
Castilho, LR1
Poi, WR1
Capaldi, ML1
Kim, GT1
Krieger, E1
d'Hoedt, B1
Scheller, H1
Jacobs, C1
Walter, C1
Wehrbein, H1
Kum, KY1
Park, JH1
Yoo, YJ1
Choi, BK1
Lee, HJ1
Lee, SJ1
Lustosa-Pereira, A1
Garcia, RB2
Bernardineli, N2
Bramante, CM2
Bortoluzzi, EA1
Gomes de Moraes, I1
Komatsu, K1
Shimada, A1
Shibata, T1
Shimoda, S1
Oida, S1
Kawasaki, K1
Nifuji, A1
Igarashi, K1
Mitani, H1
Adachi, H1
Shinoda, H1
Levin, L1
Bryson, EC1
Caplan, D1
Trope, M1

Other Studies

14 other studies available for alendronate and Root Resorption

ArticleYear
Effect of ProRoot MTA® and Biodentine® on osteoclastic differentiation and activity of mouse bone marrow macrophages.
    Journal of applied oral science : revista FOB, 2019, Jan-07, Volume: 27

    Topics: Alendronate; Animals; Blotting, Western; Bone Density Conservation Agents; Bone Marrow Cells; Calciu

2019
Low-dose combination of alendronate and atorvastatin reduces ligature-induced alveolar bone loss in rats.
    Journal of periodontal research, 2014, Volume: 49, Issue:1

    Topics: Acid Phosphatase; Alanine Transaminase; Alendronate; Alkaline Phosphatase; Alveolar Bone Loss; Anima

2014
Effects of the bisphosphonate alendronate on molars of young rats after lateral luxation.
    Dental traumatology : official publication of International Association for Dental Traumatology, 2014, Volume: 30, Issue:6

    Topics: Acid Phosphatase; Alendronate; Alveolar Process; Animals; Bone Density Conservation Agents; Dental C

2014
Effects of alendronate on osteoclast formation and activity in vitro.
    Journal of endodontics, 2015, Volume: 41, Issue:1

    Topics: Alendronate; Animals; Cathepsin K; Cell Proliferation; Cell Survival; Fibroblasts; Humans; Mice; Ost

2015
Could zoledronic acid prevent root resorption in replanted rat molar?
    Dental traumatology : official publication of International Association for Dental Traumatology, 2015, Volume: 31, Issue:6

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Diphosphonates; Imidazoles; Rats; Rats, Spra

2015
Biocompatibility evaluation of alendronate paste in rat's subcutaneous tissue.
    Dental traumatology : official publication of International Association for Dental Traumatology, 2009, Volume: 25, Issue:2

    Topics: Alendronate; Animals; Biocompatible Materials; Disease Models, Animal; Injections, Subcutaneous; Mal

2009
The effects of topical application of bisphosphonates on replanted rat molars.
    Dental traumatology : official publication of International Association for Dental Traumatology, 2010, Volume: 26, Issue:6

    Topics: Administration, Topical; Alendronate; Animals; Bone Density Conservation Agents; Citric Acid; Dental

2010
[Orthodontic treatment of patients medicated with bisphosphonates-a clinical case report].
    Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, 2013, Volume: 74, Issue:1

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Dental Implants; Female; Humans; Root Resorptio

2013
The inhibitory effect of alendronate and taurine on osteoclast differentiation mediated by Porphyromonas gingivalis sonicates in vitro.
    Journal of endodontics, 2003, Volume: 29, Issue:1

    Topics: Alendronate; Animals; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Coculture Techniques

2003
Evaluation of the topical effect of alendronate on the root surface of extracted and replanted teeth. Microscopic analysis on rats' teeth.
    Dental traumatology : official publication of International Association for Dental Traumatology, 2006, Volume: 22, Issue:1

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Desiccation; Male; Rats; Root Canal Therapy;

2006
Morphometric and microscopic evaluation of the effect of a solution of alendronate as an intracanal therapeutic agent in rat teeth submitted to late reimplantation.
    Dental traumatology : official publication of International Association for Dental Traumatology, 2007, Volume: 23, Issue:4

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Calcium Hydroxide; Male; Rats; Rats, Wistar;

2007
Long-term effects of local pretreatment with alendronate on healing of replanted rat teeth.
    Journal of periodontal research, 2008, Volume: 43, Issue:2

    Topics: Alendronate; Alveolar Bone Loss; Animals; Bone Density Conservation Agents; Dental Pulp Calcificatio

2008
Anchorage and retentive effects of a bisphosphonate (AHBuBP) on tooth movements in rats.
    American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 1994, Volume: 106, Issue:3

    Topics: Alendronate; Alveolar Bone Loss; Analysis of Variance; Animals; Dental Stress Analysis; Diphosphonat

1994
Effect of topical alendronate on root resorption of dried replanted dog teeth.
    Dental traumatology : official publication of International Association for Dental Traumatology, 2001, Volume: 17, Issue:3

    Topics: Administration, Topical; Alendronate; Animals; Ankylosis; Bicuspid; Chi-Square Distribution; Dental

2001