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alendronate and Reflex Sympathetic Dystrophy

alendronate has been researched along with Reflex Sympathetic Dystrophy in 3 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Reflex Sympathetic Dystrophy: A syndrome characterized by severe burning pain in an extremity accompanied by sudomotor, vasomotor, and trophic changes in bone without an associated specific nerve injury. This condition is most often precipitated by trauma to soft tissue or nerve complexes. The skin over the affected region is usually erythematous and demonstrates hypersensitivity to tactile stimuli and erythema. (Adams et al., Principles of Neurology, 6th ed, p1360; Pain 1995 Oct;63(1):127-33)

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effects of the antiresorptive agent alendronate at a daily oral dose of 40 mg in patients with posttraumatic complex regional pain syndrome type I (CRPS I) of the lower extremity."9.11Role of alendronate in therapy for posttraumatic complex regional pain syndrome type I of the lower extremity. ( Boutsen, Y; Brasseur, JP; Depreseux, G; Devogelaer, JP; Manicourt, DH, 2004)
"To evaluate the effects of the antiresorptive agent alendronate at a daily oral dose of 40 mg in patients with posttraumatic complex regional pain syndrome type I (CRPS I) of the lower extremity."5.11Role of alendronate in therapy for posttraumatic complex regional pain syndrome type I of the lower extremity. ( Boutsen, Y; Brasseur, JP; Depreseux, G; Devogelaer, JP; Manicourt, DH, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Manicourt, DH1
Brasseur, JP1
Boutsen, Y1
Depreseux, G1
Devogelaer, JP1
Adami, S1
Fossaluzza, V1
Gatti, D1
Fracassi, E1
Braga, V1

Trials

2 trials available for alendronate and Reflex Sympathetic Dystrophy

ArticleYear
Role of alendronate in therapy for posttraumatic complex regional pain syndrome type I of the lower extremity.
    Arthritis and rheumatism, 2004, Volume: 50, Issue:11

    Topics: Administration, Oral; Adult; Alendronate; Collagen; Collagen Type I; Double-Blind Method; Drug Admin

2004
Bisphosphonate therapy of reflex sympathetic dystrophy syndrome.
    Annals of the rheumatic diseases, 1997, Volume: 56, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Arm; Bone Density; Double-Blind Method; Female; Humans;

1997

Other Studies

1 other study available for alendronate and Reflex Sympathetic Dystrophy

ArticleYear
Complex regional pain syndrome type 1. Some treatments assessed versus placebo, limited efficacy.
    Prescrire international, 2009, Volume: 18, Issue:104

    Topics: Adrenal Cortex Hormones; Alendronate; Analgesia; Analgesics, Opioid; Antidepressive Agents; Behavior

2009