alendronate has been researched along with Periodontal Pocket in 4 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
Periodontal Pocket: An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alendronate sodium is a potent inhibitor of bone resorption which has been effectively used to control osteolysis, and to treat Paget's disease and osteoporosis." | 6.71 | The effect of alendronate sodium on alveolar bone loss in periodontitis (clinical trial). ( El-Shinnawi, UM; El-Tantawy, SI, 2003) |
| "Alendronate (ALN) increases alveolar bone density with systemic use and, has been found to increase bone formation on local delivery into the periodontal pocket." | 5.16 | Local drug delivery of alendronate gel for the treatment of patients with chronic periodontitis with diabetes mellitus: a double-masked controlled clinical trial. ( Bajaj, P; Kumari, M; Naik, SB; Pradeep, AR; Rao, NS; Sharma, A, 2012) |
| "Alendronate sodium is a potent inhibitor of bone resorption which has been effectively used to control osteolysis, and to treat Paget's disease and osteoporosis." | 2.71 | The effect of alendronate sodium on alveolar bone loss in periodontitis (clinical trial). ( El-Shinnawi, UM; El-Tantawy, SI, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, A | 2 |
| Pradeep, AR | 2 |
| Rao, NS | 1 |
| Bajaj, P | 1 |
| Naik, SB | 1 |
| Kumari, M | 1 |
| El-Shinnawi, UM | 1 |
| El-Tantawy, SI | 1 |
| Brunsvold, MA | 1 |
| Chaves, ES | 1 |
| Kornman, KS | 1 |
| Aufdemorte, TB | 1 |
| Wood, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Alendronate With β - TCP Bone Substitute in Surgical Therapy of Periodontal Intra-osseous Defects: A Randomized, Controlled Clinical Trial.[NCT02795546] | Phase 4 | 32 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for alendronate and Periodontal Pocket
| Article | Year |
|---|---|
Clinical efficacy of 1% alendronate gel as a local drug delivery system in the treatment of chronic periodontitis: a randomized, controlled clinical trial.
Topics: Adult; Alendronate; Alveolar Bone Loss; Bone Density Conservation Agents; Bone Regeneration; Chronic | 2012 |
Local drug delivery of alendronate gel for the treatment of patients with chronic periodontitis with diabetes mellitus: a double-masked controlled clinical trial.
Topics: Adult; Alendronate; Alveolar Bone Loss; Bone Density Conservation Agents; Bone Regeneration; Chi-Squ | 2012 |
The effect of alendronate sodium on alveolar bone loss in periodontitis (clinical trial).
Topics: Absorptiometry, Photon; Adult; Alendronate; Alveolar Bone Loss; Alveolar Process; Bone Density; Dent | 2003 |
1 other study available for alendronate and Periodontal Pocket
| Article | Year |
|---|---|
Effects of a bisphosphonate on experimental periodontitis in monkeys.
Topics: Alendronate; Alveolar Bone Loss; Animals; Bone Density; Dental Plaque Index; Diphosphonates; Macaca | 1992 |