alendronate has been researched along with Otospongiosis in 3 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Identify and compare phenotypic properties of osteoblasts from patients with otosclerosis (OSO), normal bones (HOB), and normal stapes (NSO) to determine a possible cause for OSO hypermineralization and assess any effects of the bisphosphonate, alendronate." | 3.80 | Differences in otosclerotic and normal human stapedial osteoblast properties are normalized by alendronate in vitro. ( Aronow, M; Eisen, M; Flynn, J; Gronowicz, G; Kveton, J; Leonard, G; Parham, K; Richardson, YL; Rodner, C, 2014) |
| "Otospongiosis is a primary osteodystrophy of the otic capsule that affects genetically predisposed individuals and leads to a progressive hearing loss." | 2.77 | The effectiveness of audiometric evaluation in drug treatment for otospongiosis. ( Cruz, OL; Penido, Nde O; Suzuki, FB; Vicente, Ade O; Yamashita, HK, 2012) |
| "Otosclerosis is a bony dyscrasia characterized by histopathological findings of osteoclast production." | 1.35 | Medical treatment of otosclerosis: rationale for use of bisphosphonates. ( Brookler, K, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gronowicz, G | 1 |
| Richardson, YL | 1 |
| Flynn, J | 1 |
| Kveton, J | 1 |
| Eisen, M | 1 |
| Leonard, G | 1 |
| Aronow, M | 1 |
| Rodner, C | 1 |
| Parham, K | 1 |
| Brookler, K | 1 |
| Vicente, Ade O | 1 |
| Yamashita, HK | 1 |
| Cruz, OL | 1 |
| Suzuki, FB | 1 |
| Penido, Nde O | 1 |
1 trial available for alendronate and Otospongiosis
| Article | Year |
|---|---|
The effectiveness of audiometric evaluation in drug treatment for otospongiosis.
Topics: Adult; Aged; Alendronate; Audiometry; Auditory Threshold; Bone Conduction; Bone Density Conservation | 2012 |
2 other studies available for alendronate and Otospongiosis
| Article | Year |
|---|---|
Differences in otosclerotic and normal human stapedial osteoblast properties are normalized by alendronate in vitro.
Topics: Adult; Alendronate; Bone Density Conservation Agents; Calcification, Physiologic; Case-Control Studi | 2014 |
Medical treatment of otosclerosis: rationale for use of bisphosphonates.
Topics: Aged; Alendronate; Animals; Bone Density Conservation Agents; Bone Resorption; Cell Death; Combined | 2008 |