Page last updated: 2024-10-22

alendronate and Osteosclerosis

alendronate has been researched along with Osteosclerosis in 7 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Osteosclerosis: An abnormal hardening or increased density of bone tissue.

Research Excerpts

ExcerptRelevanceReference
"These results suggest that etidronate may 1) inhibit the entry of NBPs into cells related to inflammation and/or necrosis, 2) inhibit the binding of NBPs to bone hydroxyapatite, 3) at least partly eliminate (or substitute for) NBPs that have already accumulated within bones, and thus 4) if used as a substitution drug for NBPs, be effective at treating or preventing NBP-associated osteonecrosis of the jaw."3.76Inhibition of necrotic actions of nitrogen-containing bisphosphonates (NBPs) and their elimination from bone by etidronate (a non-NBP): a proposal for possible utilization of etidronate as a substitution drug for NBPs. ( Endo, Y; Funayama, H; Kawamura, H; Kumamoto, H; Kuroishi, T; Oizumi, T; Sasaki, K; Sugawara, S; Takahashi, H; Yamaguchi, K; Yamamoto, M; Yokoyama, M, 2010)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Campbell, GM1
Tower, RJ1
Damm, T1
Kneissl, P1
Rambow, AC1
Schem, C1
Tiwari, S1
Glüer, CC1
Zaman, MU1
Nakamoto, T1
Tanimoto, K1
Hamada, H1
Matsuo, A1
Koizumi, T1
Satomi, T1
Chikazu, D1
Oizumi, T1
Funayama, H1
Yamaguchi, K1
Yokoyama, M1
Takahashi, H1
Yamamoto, M1
Kuroishi, T1
Kumamoto, H1
Sasaki, K1
Kawamura, H1
Sugawara, S1
Endo, Y1
Treister, NS1
Friedland, B1
Woo, SB1
Chiu, CT1
Chiang, WF1
Chuang, CY1
Chang, SW1
O'Ryan, FS1
Lo, JC1

Other Studies

7 other studies available for alendronate and Osteosclerosis

ArticleYear
Tracking the Progression of Osteolytic and Osteosclerotic Lesions in Mice Using Serial In Vivo μCT: Applications to the Assessment of Bisphosphonate Treatment Efficacy.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2018, Volume: 33, Issue:3

    Topics: Alendronate; Animals; Bone Resorption; Cell Line, Tumor; Diphosphonates; Disease Progression; Female

2018
A retrospective study of digital subtraction technique to detect sclerotic changes in alveolar bone on intraoral radiographs of bisphosphonate-treated patients.
    Dento maxillo facial radiology, 2013, Volume: 42, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Alveolar Process; Anatomic Landmarks; Bisphosphonate-As

2013
A simple evaluation method for early detection of bisphosphonate-related osteonecrosis of the mandible using computed tomography.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2014, Volume: 42, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Alendronate; Alveolar Process; Bisphosphonate-Ass

2014
Inhibition of necrotic actions of nitrogen-containing bisphosphonates (NBPs) and their elimination from bone by etidronate (a non-NBP): a proposal for possible utilization of etidronate as a substitution drug for NBPs.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2010, Volume: 68, Issue:5

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Bone Resorption; Diphosphonates; Ear, Extern

2010
Use of cone-beam computerized tomography for evaluation of bisphosphonate-associated osteonecrosis of the jaws.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2010, Volume: 109, Issue:5

    Topics: Adult; Aged; Alendronate; Bone Density Conservation Agents; Cone-Beam Computed Tomography; Diphospho

2010
Resolution of oral bisphosphonate and steroid-related osteonecrosis of the jaw--a serial case analysis.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2010, Volume: 68, Issue:5

    Topics: Actinomycosis; Administration, Oral; Aged; Aged, 80 and over; Alendronate; Anti-Bacterial Agents; Bo

2010
Bisphosphonate-related osteonecrosis of the jaw in patients with oral bisphosphonate exposure: clinical course and outcomes.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2012, Volume: 70, Issue:8

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alendronate; Anti-Bacterial Agents; Antirheumatic Age

2012