Page last updated: 2024-10-22

alendronate and Osteonecrosis

alendronate has been researched along with Osteonecrosis in 107 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Osteonecrosis: Death of a bone or part of a bone, either atraumatic or posttraumatic.

Research Excerpts

ExcerptRelevanceReference
"To conduct a literature review on sodium alendronate, focusing on osteonecrosis of the jaws, a serious potential side effect."8.91Important aspects concerning alendronate-related osteonecrosis of the jaws: a literature review. ( Cherubini, K; Figueiredo, MA; Iglesias, JE; Salum, FG, 2015)
"The purpose of the current review was to determine the efficacy of alendronate for preventing collapse of femoral head in adult patients with nontraumatic avascular osteonecrosis of femoral head (ANFH)."8.90Efficacy of alendronate for preventing collapse of femoral head in adult patients with nontraumatic osteonecrosis. ( Hong, YC; Lin, T; Luo, RB; Shi, JB; Zhong, HM, 2014)
"We aimed to establish the incidence of alendronate-related osteonecrosis of the jaw (ONJ) in the southeast of Scotland, and to assess the effect of corticosteroids on it."7.83Epidemiological study of alendronate-related osteonecrosis of the jaw in the southeast of Scotland. ( Lopes, V; Malden, N; Ralston, S; Sammut, S, 2016)
"This work aimed at determining whether bisphosphonate therapy produces a sufficient condition for jaw osteonecrosis after tooth extraction."7.77Association between bisphosphonates and jaw osteonecrosis: a study in Wistar rats. ( Azambuja, AA; Campos, MM; Cherubini, K; Maahs, MP; Salum, FG, 2011)
"The aim of this study was to evaluate a possible role of microcracks in the pathogenesis of bisphosphonate-related osteonecrosis of the jaw (ONJ) and to discuss an etiological model."7.76Importance of microcracks in etiology of bisphosphonate-related osteonecrosis of the jaw: a possible pathogenetic model of symptomatic and non-symptomatic osteonecrosis of the jaw based on scanning electron microscopy findings. ( Eufinger, H; Hoefert, S; Schmitz, I; Tannapfel, A, 2010)
"Several recent medical articles have described multiple cases of unusual low-impact subtrochanteric stress fractures or completed fractures of the femur in patients who have been on the bisphosphonate alendronate for several years for osteoporosis or osteopenia."7.75Bisphosphonates and low-impact femoral fractures: current evidence on alendronate-fracture risk. ( Schneider, JP, 2009)
"Bisphosphonate use, in particular pamidronate, improved pain scores, analgesic requirement and musculoskeletal function in patients with osteonecrosis occurring as a complication of childhood ALL therapy."5.14Use of bisphosphonates for the treatment of osteonecrosis as a complication of therapy for childhood acute lymphoblastic leukaemia (ALL). ( Carter, T; Cole, C; Kotecha, RS; Lee, SJ; Murray, KJ; Powers, N, 2010)
"To conduct a literature review on sodium alendronate, focusing on osteonecrosis of the jaws, a serious potential side effect."4.91Important aspects concerning alendronate-related osteonecrosis of the jaws: a literature review. ( Cherubini, K; Figueiredo, MA; Iglesias, JE; Salum, FG, 2015)
"The purpose of the current review was to determine the efficacy of alendronate for preventing collapse of femoral head in adult patients with nontraumatic avascular osteonecrosis of femoral head (ANFH)."4.90Efficacy of alendronate for preventing collapse of femoral head in adult patients with nontraumatic osteonecrosis. ( Hong, YC; Lin, T; Luo, RB; Shi, JB; Zhong, HM, 2014)
" Usually with alendronate the risk of bisphosphonate-related osteonecrosis of jaw (BRONJ) wears off after 12 months."3.96Osteonecrosis and spontaneous exfoliation of dental implants associated with oral bisphosphonate therapy: a case report. ( Hilal, G; Rawal, SY, 2020)
"We aimed to establish the incidence of alendronate-related osteonecrosis of the jaw (ONJ) in the southeast of Scotland, and to assess the effect of corticosteroids on it."3.83Epidemiological study of alendronate-related osteonecrosis of the jaw in the southeast of Scotland. ( Lopes, V; Malden, N; Ralston, S; Sammut, S, 2016)
"Between 2006 and 2009, 17 consecutive patients (mean age 68 years) with clinical and radiographic signs of knee osteonecrosis were identified and given alendronate, 70 mg perorally, once a week for a minimum of 6 months."3.78Treatment of spontaneous osteonecrosis of the knee (SPONK) by a bisphosphonate. ( Geijer, M; Jureus, J; Lindstrand, A; Roberts, D; Tägil, M, 2012)
"This work aimed at determining whether bisphosphonate therapy produces a sufficient condition for jaw osteonecrosis after tooth extraction."3.77Association between bisphosphonates and jaw osteonecrosis: a study in Wistar rats. ( Azambuja, AA; Campos, MM; Cherubini, K; Maahs, MP; Salum, FG, 2011)
"twenty-three ONJ patients had taken alendronate for osteoporosis treatment, and the s-CTX testing results were low levels of 10-192 pg/ml (mean: 93."3.77Retrospective study of two biochemical markers for the risk assessment of oral bisphosphonate-related osteonecrosis of the jaws: can they be utilized as risk markers? ( Chung, DJ; Kim, DY; Kwon, YD; Ohe, JY; Park, YD, 2011)
"The aim of this study was to evaluate a possible role of microcracks in the pathogenesis of bisphosphonate-related osteonecrosis of the jaw (ONJ) and to discuss an etiological model."3.76Importance of microcracks in etiology of bisphosphonate-related osteonecrosis of the jaw: a possible pathogenetic model of symptomatic and non-symptomatic osteonecrosis of the jaw based on scanning electron microscopy findings. ( Eufinger, H; Hoefert, S; Schmitz, I; Tannapfel, A, 2010)
"These results suggest that etidronate may 1) inhibit the entry of NBPs into cells related to inflammation and/or necrosis, 2) inhibit the binding of NBPs to bone hydroxyapatite, 3) at least partly eliminate (or substitute for) NBPs that have already accumulated within bones, and thus 4) if used as a substitution drug for NBPs, be effective at treating or preventing NBP-associated osteonecrosis of the jaw."3.76Inhibition of necrotic actions of nitrogen-containing bisphosphonates (NBPs) and their elimination from bone by etidronate (a non-NBP): a proposal for possible utilization of etidronate as a substitution drug for NBPs. ( Endo, Y; Funayama, H; Kawamura, H; Kumamoto, H; Kuroishi, T; Oizumi, T; Sasaki, K; Sugawara, S; Takahashi, H; Yamaguchi, K; Yamamoto, M; Yokoyama, M, 2010)
"Several recent medical articles have described multiple cases of unusual low-impact subtrochanteric stress fractures or completed fractures of the femur in patients who have been on the bisphosphonate alendronate for several years for osteoporosis or osteopenia."3.75Bisphosphonates and low-impact femoral fractures: current evidence on alendronate-fracture risk. ( Schneider, JP, 2009)
"Recently, some reports indicate that osteonecrosis of the jaws could occur after taking drugs containing hisphosphonates, including alendronate, pamidronate and zolendronate, which are widely used to treat osteoporosis and metastatic skeletal lesions in clinic."3.73[Advances in the research of bisphosphonate-associated osteonecrosis of the jaws]. ( Ji, T; Ruan, M; Zhang, CP, 2006)
"The name, osteonecrosis, is misleading because the primary histopathological lesion is osteocyte apoptosis."2.48Glucocorticoid-induced osteonecrosis. ( Weinstein, RS, 2012)
"They are indicated for the treatment of osteoporosis."2.44Osteochemonecrosis of jaws and bisphosphonates. ( Beirne, JC; Khosa, AD; Nayyar, MS, 2007)
"etidronate) have been associated with acute renal failure."2.44Safety considerations with bisphosphonates for the treatment of osteoporosis. ( Civitelli, R; Emkey, R; Strampel, W, 2007)
" The variety of bisphosphonates currently available to us provides a wide range of tolerability and dosing profiles thus necessitating a thorough comparison of the most recent oral and intravenous bisphosphonates to differentiate the clinical context in which they should be used."2.43Tolerability of different dosing regimens of bisphosphonates for the treatment of osteoporosis and malignant bone disease. ( Adachi, JD; Beattie, K; Bobba, RS; Kumbhare, D; Parkinson, B, 2006)
"There are very few cases of pathological fracture induced by pancreatitis that affect the vertebrae."1.37Pathological fracture due to vertebral osteonecrosis associated with pancreatitis. ( Baba, T; Kaneko, H; Shitoto, K; Yoshioka, C, 2011)
"Alendronate was the most frequently implicated (six cases) and risedronate (five cases)."1.36[Jaw osteonecrosis induced by oral biphosphonates: 12 cases]. ( Barrier, A; Descroix, V; Goudot, P; Lescaille, G; Rigolet, A; Ruhin, B, 2010)
" Twelve patients who presented with exposed bone associated with bisphosphonates were reviewed to determine the type, dosage and duration of their bisphosphonate therapy, presenting findings, comorbidities and the event that incited the bone exposure."1.34Bisphosphonate-associated osteonecrosis of the jaw in patients with multiple myeloma and breast cancer. ( Alati, C; Allegra, A; Alonci, A; Cicciù, M; De Ponte, FS; Musolino, C; Nastro, E; Oteri, G; Quartarone, E, 2007)
"No osteonecrosis was noted immediately postoperatively or during the follow-up period in 61 patients."1.34Implant placement with or without simultaneous tooth extraction in patients taking oral bisphosphonates: postoperative healing, early follow-up, and the incidence of complications in two private practices. ( Fugazzotto, PA; Jaffin, R; Kumar, A; Lightfoot, WS, 2007)
"Sixty-two (52."1.33Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment. ( Broumand, V; Fortin, M; Marx, RE; Sawatari, Y, 2005)
" Current reports have focused on therapy-resistant osteonecrosis of the jaws as a possible side effect of bisphosphonates."1.33[Osteonecrosis of the jaws as a possible adverse effect of the use of bisphosphonates]. ( Eufinger, H; Hoefert, S, 2005)
"Here we report 29 cases of bone necrosis of the jaws in patients treated with pamidronate (Aredia), zoledronate (Zometa) and alendronate: 15 underwent surgical procedures and 14 occurred spontaneously."1.33Bone necrosis of the jaws associated with bisphosphonate treatment: a report of twenty-nine cases. ( Bonaninil, M; Corcione, L; Corradi, D; D'Aleo, P; Ferrari, S; Guidotti, R; Manfredi, M; Meleti, M; Merigo, E; Poli, T; Ripasarti, A; Sesenna, E; Vescovi, P; Zanzucchi, E, 2006)
"As revascularization follows, bone resorption may lead to collapse in load bearing areas during the remodeling."1.32Alendronate prevents collapse in mechanically loaded osteochondral grafts: a bone chamber study in rats. ( Aspenberg, P; Astrand, J; Tägil, M; Westman, L, 2004)

Research

Studies (107)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's62 (57.94)29.6817
2010's43 (40.19)24.3611
2020's2 (1.87)2.80

Authors

AuthorsStudies
Rawal, SY1
Hilal, G1
Rong, K1
Li, X1
Jiang, W1
Wu, X1
Xia, Q1
Chen, J1
Yin, X1
Basile, P1
Falk, N1
Khominsky, A1
Lim, M1
Agarwala, S1
Vijayvargiya, M1
Chiu, WY1
Lee, JJ1
Tsai, KS1
Peled, E1
Bejar, J1
Barak, M1
Orion, E1
Norman, D1
Ulmner, M1
Jarnbring, F1
Törring, O1
Iglesias, JE1
Salum, FG2
Figueiredo, MA1
Cherubini, K2
Vaishya, R1
Vijay, V1
Vaish, A1
Hong, YC1
Luo, RB1
Lin, T1
Zhong, HM1
Shi, JB1
Yuan, H1
Tanaka, J1
Kokuryo, S1
Yoshiga, D1
Tsurushima, H1
Sakaguchi, O1
Habu, M1
Nishihara, T1
Yoshioka, I1
Tominaga, K1
Kaipatur, N1
Major, P1
Stevenson, T1
Pehowich, D1
Adeeb, S1
Doschak, M1
Amin, NL1
James, RM1
Phillips, R1
Sammut, S1
Malden, N1
Lopes, V1
Ralston, S1
Wong, YK1
Cheng, JC1
Lehrer, S1
Montazem, A1
Ramanathan, L1
Pessin-Minsley, M1
Pfail, J1
Stock, RG1
Kogan, R1
Sedghizadeh, PP1
Stanley, K1
Caligiuri, M1
Hofkes, S1
Lowry, B1
Shuler, CF1
Barrow, SY1
Thomas, MV1
Straus, SE1
Aragon-Ching, JB1
Ning, YM1
Chen, CC1
Latham, L1
Guadagnini, JP1
Gulley, JL1
Arlen, PM1
Wright, JJ1
Parnes, H1
Figg, WD1
Dahut, WL1
Geusens, P1
Schneider, JP1
Lazarovici, TS2
Yahalom, R1
Taicher, S1
Elad, S1
Hardan, I1
Yarom, N2
Kallmes, DF1
Rad, AE1
Gray, LA1
McDonald, RJ1
Clarke, BL1
Stanton, DC1
Balasanian, E1
Magliocca, KR1
Stavropoulos, MF1
Bhattacharyya, I1
Cohen, DM1
Zahrowski, JJ1
Kwon, YD3
Kim, YR1
Choi, BJ1
Lee, DW1
Kim, DY3
Harada, A1
Hikita, H1
Miyazawa, K1
Tabuchi, M1
Kimura, M1
Goto, S1
Kunchur, R1
Need, A1
Hughes, T1
Goss, A1
Wongchuensoontorn, C1
Liebehenschel, N1
Wagner, K1
Fakler, O1
Gutwald, R1
Schmelzeisen, R1
Sauerbier, S1
O'Ryan, FS2
Khoury, S1
Liao, W1
Han, MM1
Hui, RL2
Baer, D1
Martin, D2
Liberty, D1
Lo, JC2
Hoefert, S2
Schmitz, I1
Tannapfel, A1
Eufinger, H2
Bocanegra-Pérez, S1
Vicente-Barrero, M1
Sosa-Henríquez, M1
Gebaguer Blanco, A1
Knezevic, M1
Castellano-Navarro, JM1
Burr, DB2
Allen, MR2
Moynihan, R2
Gordon, NP1
Yang, J1
Hutchinson, M1
Lathon, PV1
Sanchez, G1
Silver, P1
Chandra, M1
McCloskey, CA1
Staffa, JA1
Willy, M1
Selby, JV1
Go, AS1
Ohe, JY2
Yoo, JY1
Walter, C1
Kotecha, RS1
Powers, N1
Lee, SJ1
Murray, KJ1
Carter, T1
Cole, C1
Gates, BJ1
Sonnett, TE1
Duvall, CA1
Dobbins, EK1
Oizumi, T1
Funayama, H1
Yamaguchi, K1
Yokoyama, M1
Takahashi, H1
Yamamoto, M1
Kuroishi, T1
Kumamoto, H1
Sasaki, K1
Kawamura, H1
Sugawara, S1
Endo, Y1
Baba, T1
Shitoto, K1
Yoshioka, C1
Kaneko, H1
Treister, NS1
Friedland, B1
Woo, SB2
Kraenzlin, ME1
Graf, C1
Meier, C1
Kraenzlin, C1
Friedrich, NF1
Chiu, CT1
Chiang, WF1
Chuang, CY1
Chang, SW1
Kuijpers, SC1
van Roessel, EW1
van Merkesteyn, JP1
Migliorati, CA1
Mattos, K1
Palazzolo, MJ1
Scoletta, M1
Arduino, PG2
Dalmasso, P1
Broccoletti, R2
Mozzati, M1
Hunter, SA1
Orheim, R1
Sazon, M1
Newman, H1
Woll, JE1
Bergevin, M1
Barrier, A1
Lescaille, G1
Rigolet, A1
Descroix, V1
Goudot, P1
Ruhin, B1
Maahs, MP1
Azambuja, AA1
Campos, MM1
Pozzi, S1
Raje, N1
Fedele, S1
Porter, SR1
D'Aiuto, F1
Aljohani, S1
Vescovi, P2
Manfredi, M2
Musciotto, A1
Di Fede, O1
Campisi, G1
Chung, DJ1
Park, YD1
Grey, A1
Cheung, A1
Seeman, E1
Pazianas, M1
Chtioui, H1
Lamine, F1
Daghfous, R1
Alloh Amichia, YC1
Le Bars, P1
Giumelli, B1
Soueidan, A1
Conte-Neto, N1
Bastos, AS1
Spolidorio, LC1
Marcantonio, RA1
Marcantonio, E1
Kang, HS1
Lee, JW1
Kim, JS1
Sharma, V1
Nagaraj, S1
Choksey, U1
Hegde, A1
Samant, R1
Balakrishnan, C1
Bartl, R1
Weinstein, RS1
Scully, C1
Brooke, AE1
Jureus, J1
Lindstrand, A1
Geijer, M1
Roberts, D1
Tägil, M2
Ruggiero, SL1
Mehrotra, B1
Astrand, J1
Westman, L1
Aspenberg, P1
Carter, G1
Goss, AN1
Doecke, C1
Hande, K1
Richardson, PG1
Sarathy, AP1
Bourgeois, SL1
Goodell, GG1
Marx, RE3
Sawatari, Y1
Fortin, M1
Broumand, V1
Robb-Nicholson, C2
Alexander, RE1
Marunick, M1
Gordon, S1
Nase, JB1
Suzuki, JB1
Ponte Fernández, N1
Estefania Fresco, R1
Aguirre Urizar, JM1
Talbi, M1
Carrie, F1
Meley, M1
Bobba, RS1
Beattie, K1
Parkinson, B1
Kumbhare, D1
Adachi, JD1
Nastro, E1
Musolino, C1
Allegra, A1
Oteri, G1
Cicciù, M1
Alonci, A1
Quartarone, E1
Alati, C1
De Ponte, FS1
Merigo, E1
Meleti, M1
Guidotti, R1
Ripasarti, A1
Zanzucchi, E1
D'Aleo, P1
Corradi, D1
Corcione, L1
Sesenna, E1
Ferrari, S1
Poli, T1
Bonaninil, M1
Rutkowski, JL1
Johnson, DA1
Smith, DM1
Harper, RP1
Fung, E1
Letonturier, P1
Khosa, AD1
Nayyar, MS1
Beirne, JC1
Ruan, M1
Ji, T1
Zhang, CP1
Malden, NJ1
Pai, AY1
Løkken, P1
Skoglund, LA1
Skjelbred, P1
Strampel, W1
Emkey, R1
Civitelli, R1
Fugazzotto, PA1
Lightfoot, WS1
Jaffin, R1
Kumar, A1
Levin, L1
Laviv, A1
Schwartz-Arad, D1
Cillo, JE1
Ulloa, JJ1
Lee, CY1
David, T1
Nishime, M1
Bianchi, ML1
Limonta, C1
Frasunkiewicz, J1
Biggioggero, M1
Vai, S1
Khan, A1
Udvardy, E1
Redl, P1
Márton, I1
Engroff, SL1
Coletti, D1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Controlled Trial of Cesamet(R) (Nabilone) for the Prevention of Postoperative Nausea and Vomiting in Elective Surgery[NCT02115529]Phase 2331 participants (Actual)Interventional2014-04-30Completed
The Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral Head[NCT05706909]20 participants (Anticipated)Observational2023-02-08Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

16 reviews available for alendronate and Osteonecrosis

ArticleYear
"Spontaneous" medication-related osteonecrosis of the jaw; two case reports and a systematic review.
    Australian dental journal, 2018, Volume: 63, Issue:4

    Topics: Aged; Alendronate; Antineoplastic Agents; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone D

2018
Important aspects concerning alendronate-related osteonecrosis of the jaws: a literature review.
    Gerodontology, 2015, Volume: 32, Issue:3

    Topics: Alendronate; Bone Density Conservation Agents; Humans; Jaw Diseases; Osteonecrosis

2015
Efficacy of alendronate for preventing collapse of femoral head in adult patients with nontraumatic osteonecrosis.
    BioMed research international, 2014, Volume: 2014

    Topics: Alendronate; Bone Density Conservation Agents; Femur Head; Humans; Lithotripsy; Osteonecrosis; Treat

2014
QUESTION 1: Should we be using bisphosphonates for osteonecrosis complicating childhood acute lymphoblastic leukaemia?
    Archives of disease in childhood, 2016, Volume: 101, Issue:3

    Topics: Adolescent; Alendronate; Antineoplastic Agents; Bone Density Conservation Agents; Diphosphonates; Fe

2016
Bisphosphonates for postmenopausal osteoporosis: determining duration of treatment.
    Current osteoporosis reports, 2009, Volume: 7, Issue:1

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Diphosphonates; Etidronic Acid; Female; Frac

2009
[Alendronate for treatment of osteoporoses].
    Nihon rinsho. Japanese journal of clinical medicine, 2009, Volume: 67, Issue:5

    Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Evidence-Based Medicine; Femoral Fractu

2009
Review of osteoporosis pharmacotherapy for geriatric patients.
    The American journal of geriatric pharmacotherapy, 2009, Volume: 7, Issue:6

    Topics: Aged; Alendronate; Bone Density; Calcitonin; Calcium, Dietary; Diphosphonates; Economics, Pharmaceut

2009
Osteonecrosis of the jaw and the role of macrophages.
    Journal of the National Cancer Institute, 2011, Feb-02, Volume: 103, Issue:3

    Topics: Alendronate; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bone

2011
Glucocorticoid-induced osteonecrosis.
    Endocrine, 2012, Volume: 41, Issue:2

    Topics: Adult; Alendronate; Animals; Anti-Inflammatory Agents; Apoptosis; Bone Density Conservation Agents;

2012
Glucocorticoid-induced osteonecrosis.
    Endocrine, 2012, Volume: 41, Issue:2

    Topics: Adult; Alendronate; Animals; Anti-Inflammatory Agents; Apoptosis; Bone Density Conservation Agents;

2012
Glucocorticoid-induced osteonecrosis.
    Endocrine, 2012, Volume: 41, Issue:2

    Topics: Adult; Alendronate; Animals; Anti-Inflammatory Agents; Apoptosis; Bone Density Conservation Agents;

2012
Glucocorticoid-induced osteonecrosis.
    Endocrine, 2012, Volume: 41, Issue:2

    Topics: Adult; Alendronate; Animals; Anti-Inflammatory Agents; Apoptosis; Bone Density Conservation Agents;

2012
Bisphosphonates and oral pathology I. General and preventive aspects.
    Medicina oral, patologia oral y cirugia bucal, 2006, Aug-01, Volume: 11, Issue:5

    Topics: Administration, Oral; Alendronate; Antibiotic Prophylaxis; Bone Density Conservation Agents; Bone Re

2006
Tolerability of different dosing regimens of bisphosphonates for the treatment of osteoporosis and malignant bone disease.
    Drug safety, 2006, Volume: 29, Issue:12

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Bone Neoplasms; Diphosphonates; Etidronic Ac

2006
Osteochemonecrosis of jaws and bisphosphonates.
    Irish medical journal, 2007, Volume: 100, Issue:3

    Topics: Alendronate; Bone Density Conservation Agents; Etidronic Acid; Humans; Jaw; Osteonecrosis; Osteoporo

2007
[Diphosphonate therapy and osteonecrosis of the jaw].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2007, Aug-09, Volume: 127, Issue:15

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Dental Care; Diphosphonates; Female; Humans; Ja

2007
Safety considerations with bisphosphonates for the treatment of osteoporosis.
    Drug safety, 2007, Volume: 30, Issue:9

    Topics: Acute-Phase Reaction; Administration, Oral; Alendronate; Bone Density Conservation Agents; Diphospho

2007
Use of platelet-rich plasma in the management of oral biphosphonate-associated osteonecrosis of the jaw: a report of 2 cases.
    The Journal of oral implantology, 2007, Volume: 33, Issue:6

    Topics: Actinomycosis; Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Diphosphonate

2007
[Osteonecrosis of the jaw developing during bisphosphonate treatment].
    Magyar onkologia, 2008, Volume: 52, Issue:1

    Topics: Alendronate; Anti-Infective Agents; Bone Density Conservation Agents; Bone Neoplasms; Bone Remodelin

2008

Trials

3 trials available for alendronate and Osteonecrosis

ArticleYear
Higher incidence of Osteonecrosis of the Jaw (ONJ) in patients with metastatic castration resistant prostate cancer treated with anti-angiogenic agents.
    Cancer investigation, 2009, Volume: 27, Issue:2

    Topics: Adult; Aged; Alendronate; Angiogenesis Inhibitors; Diphosphonates; Humans; Ibandronic Acid; Incidenc

2009
Clinical investigation of C-terminal cross-linking telopeptide test in prevention and management of bisphosphonate-associated osteonecrosis of the jaws.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009, Volume: 67, Issue:6

    Topics: Administration, Oral; Age Factors; Aged; Aged, 80 and over; Alendronate; Biomarkers; Bone Density Co

2009
Use of bisphosphonates for the treatment of osteonecrosis as a complication of therapy for childhood acute lymphoblastic leukaemia (ALL).
    Pediatric blood & cancer, 2010, Jul-01, Volume: 54, Issue:7

    Topics: Administration, Oral; Adolescent; Adrenal Cortex Hormones; Alendronate; Antineoplastic Combined Chem

2010

Other Studies

88 other studies available for alendronate and Osteonecrosis

ArticleYear
Osteonecrosis and spontaneous exfoliation of dental implants associated with oral bisphosphonate therapy: a case report.
    Australian dental journal, 2020, Volume: 65, Issue:1

    Topics: Alendronate; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; D

2020
Alendronate Alleviated Femoral Head Necrosis and Upregulated BMP2/EIF2AK3/EIF2A/ATF4 Pathway in Liquid Nitrogen Treated Rats.
    Drug design, development and therapy, 2021, Volume: 15

    Topics: Activating Transcription Factor 4; Alendronate; Animals; Bone Morphogenetic Protein 2; eIF-2 Kinase;

2021
Anterolateral hip pain · no specific injury · Dx?
    The Journal of family practice, 2018, Volume: 67, Issue:8

    Topics: Alendronate; Arthralgia; Athletes; Bone Density Conservation Agents; Glucocorticoids; Hip Joint; Hoc

2018
Bisphosphonate combination therapy for non-femoral avascular necrosis.
    Journal of orthopaedic surgery and research, 2019, Apr-24, Volume: 14, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Aged; Alendronate; Bone Densit

2019
Atypical femoral fractures shortly after osteonecrosis of the jaw in a postmenopausal woman taking alendronate for osteoporosis.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:4

    Topics: Administration, Oral; Alendronate; Bone Density Conservation Agents; Female; Femoral Fractures; Huma

2013
Core decompression and alendronate treatment of the osteonecrotic rat femoral head: computer-assisted analysis.
    International journal of experimental pathology, 2013, Volume: 94, Issue:3

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Combined Modality Therapy; Decompression, Su

2013
Osteonecrosis of the jaw in Sweden associated with the oral use of bisphosphonate.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2014, Volume: 72, Issue:1

    Topics: Administration, Oral; Age Factors; Aged; Aged, 80 and over; Alendronate; Bisphosphonate-Associated O

2014
Spontaneous osteonecrosis of the knee: an unusual cause of knee pain.
    BMJ case reports, 2014, Apr-30, Volume: 2014

    Topics: Acute Disease; Adult; Alendronate; Arthralgia; Diclofenac; Disease Progression; Humans; Knee Joint;

2014
Comment on "Efficacy of Alendronate for Preventing Collapse of Femoral Head in Adult Patients with Nontraumatic Osteonecrosis".
    BioMed research international, 2015, Volume: 2015

    Topics: Alendronate; Bone Density Conservation Agents; Femur Head; Humans; Osteonecrosis

2015
An osteonecrosis model induced by oral bisphosphonate in ovariectomised rats.
    Oral diseases, 2015, Volume: 21, Issue:8

    Topics: Administration, Oral; Alendronate; Animals; Bone Density Conservation Agents; Disease Models, Animal

2015
Impact of selective alveolar decortication on bisphosphonate burdened alveolar bone during orthodontic tooth movement.
    Archives of oral biology, 2015, Volume: 60, Issue:11

    Topics: Alendronate; Alveolar Process; Animals; Bone Remodeling; Electron Probe Microanalysis; Female; Maxil

2015
Epidemiological study of alendronate-related osteonecrosis of the jaw in the southeast of Scotland.
    The British journal of oral & maxillofacial surgery, 2016, Volume: 54, Issue:5

    Topics: Aged; Aged, 80 and over; Alendronate; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Densi

2016
Bisphosphonate-related osteonecrosis of the jaws--report of 2 cases and strategies on prevention and management.
    Quintessence international (Berlin, Germany : 1985), 2008, Volume: 39, Issue:3

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Bone Neoplasms; Diphosphonates; Female; Humans;

2008
Bisphosphonate-induced osteonecrosis of the jaws, bone markers, and a hypothesized candidate gene.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009, Volume: 67, Issue:1

    Topics: Alendronate; Biomarkers; Bone and Bones; Bone Density Conservation Agents; Collagen Type I; Cysteine

2009
Oral bisphosphonate use and the prevalence of osteonecrosis of the jaw: an institutional inquiry.
    Journal of the American Dental Association (1939), 2009, Volume: 140, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Female

2009
Is your knowledge up-to-date? Bisphosphonate-related osteonecrosis of the jaw.
    International journal of dental hygiene, 2008, Volume: 6, Issue:4

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Denture, Complete, Upper; Diphosphonates; Femal

2008
Evidence-based dentistry and the concept of harm.
    Dental clinics of North America, 2009, Volume: 53, Issue:1

    Topics: Alendronate; Bone Density Conservation Agents; Chronic Periodontitis; Clinical Competence; Databases

2009
Bisphosphonates and low-impact femoral fractures: current evidence on alendronate-fracture risk.
    Geriatrics, 2009, Volume: 64, Issue:1

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Bone Resorption; Drug Administration Schedule;

2009
Bisphosphonate-related osteonecrosis of the jaws: a single-center study of 101 patients.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009, Volume: 67, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alendronate; Angiogenesis Inhibitors; Anti-Bac

2009
Bisphosphonates are not associated with vertebral osteonecrosis.
    Journal of bone and mineral metabolism, 2009, Volume: 27, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Bone Density; Diphosphonates; Female; Humans; Male; Mid

2009
Outcome of surgical management of bisphosphonate-related osteonecrosis of the jaws: review of 33 surgical cases.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009, Volume: 67, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Diphosphonates; Femal

2009
A compounded diagnosis: maxillary osteochemonecrosis in the setting of low dose radiotherapy.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009, Volume: 67, Issue:5

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Diagnosis, Differential; Diphosphonates; Female

2009
Oral bisphosphonates.
    Journal of the American Dental Association (1939), 2009, Volume: 140, Issue:5

    Topics: Alendronate; Bone Density Conservation Agents; Female; Humans; Jaw Diseases; Osteonecrosis; Osteopor

2009
Oral bisphosphonate-related osteonecrosis of the jaws: favorable outcome after bisphosphonate holiday.
    Quintessence international (Berlin, Germany : 1985), 2009, Volume: 40, Issue:4

    Topics: Administration, Oral; Aged; Alendronate; Bone Density Conservation Agents; Collagen Type I; Drug Adm

2009
Bisphosphonate administration prior to tooth extraction delays initial healing of the extraction socket in rats.
    Journal of bone and mineral metabolism, 2009, Volume: 27, Issue:6

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Bone Resorption; Diphosphonates; Equipment D

2009
Pathological fractures in patients caused by bisphosphonate-related osteonecrosis of the jaws: report of 3 cases.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009, Volume: 67, Issue:6

    Topics: Administration, Oral; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Diphosphonat

2009
Intravenous bisphosphonate-related osteonecrosis of the jaw: bone scintigraphy as an early indicator.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009, Volume: 67, Issue:7

    Topics: Administration, Oral; Alendronate; Bone Density Conservation Agents; Diphosphonates; Early Diagnosis

2009
Importance of microcracks in etiology of bisphosphonate-related osteonecrosis of the jaw: a possible pathogenetic model of symptomatic and non-symptomatic osteonecrosis of the jaw based on scanning electron microscopy findings.
    Clinical oral investigations, 2010, Volume: 14, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Connective Tissue; Di

2010
[Osteonecrosis of the jaw secondary to oral alendronate: Report of three cases].
    Revista medica de Chile, 2009, Volume: 137, Issue:2

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Diabetes Mellitus, Type 2; F

2009
Mandibular necrosis in beagle dogs treated with bisphosphonates.
    Orthodontics & craniofacial research, 2009, Volume: 12, Issue:3

    Topics: Alendronate; Alveolar Process; Animals; Bone Density Conservation Agents; Bone Matrix; Bone Remodeli

2009
Battle over popular bone drug Fosamax bursts into court.
    BMJ (Clinical research ed.), 2009, Aug-06, Volume: 339

    Topics: Alendronate; Bone Density Conservation Agents; Drug Industry; Humans; Jaw Diseases; Legislation, Dru

2009
US judge rules Merck won't face "punitive damages" in first Fosamax case.
    BMJ (Clinical research ed.), 2009, Aug-06, Volume: 339

    Topics: Alendronate; Bone Density Conservation Agents; Bone Remodeling; Drug Industry; Humans; Jaw Diseases;

2009
Prevalence of osteonecrosis of the jaw in patients with oral bisphosphonate exposure.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2010, Volume: 68, Issue:2

    Topics: Administration, Oral; Aged; Alendronate; Bone Density Conservation Agents; California; Cross-Section

2010
Correlation between serum C-terminal cross-linking telopeptide of type I collagen and staging of oral bisphosphonate-related osteonecrosis of the jaws.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009, Volume: 67, Issue:12

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alendronate; Biomarkers; Bone Density Conservation Ag

2009
Inhibition of necrotic actions of nitrogen-containing bisphosphonates (NBPs) and their elimination from bone by etidronate (a non-NBP): a proposal for possible utilization of etidronate as a substitution drug for NBPs.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2010, Volume: 68, Issue:5

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Bone Resorption; Diphosphonates; Ear, Extern

2010
Pathological fracture due to vertebral osteonecrosis associated with pancreatitis.
    Archives of orthopaedic and trauma surgery, 2011, Volume: 131, Issue:1

    Topics: Alendronate; Bone and Bones; Bone Density Conservation Agents; Disease Progression; Fat Necrosis; Fr

2011
Use of cone-beam computerized tomography for evaluation of bisphosphonate-associated osteonecrosis of the jaws.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2010, Volume: 109, Issue:5

    Topics: Adult; Aged; Alendronate; Bone Density Conservation Agents; Cone-Beam Computed Tomography; Diphospho

2010
Possible beneficial effect of bisphosphonates in osteonecrosis of the knee.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2010, Volume: 18, Issue:12

    Topics: Alendronate; Alkaline Phosphatase; Amino Acids; Bone Density Conservation Agents; Bone Marrow Diseas

2010
Resolution of oral bisphosphonate and steroid-related osteonecrosis of the jaw--a serial case analysis.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2010, Volume: 68, Issue:5

    Topics: Actinomycosis; Administration, Oral; Aged; Aged, 80 and over; Alendronate; Anti-Bacterial Agents; Bo

2010
Unusual case of a conservatively treated pathological fracture after sequestrectomy in a patient with long-term oral bisphosphonate use.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2011, Volume: 39, Issue:1

    Topics: Administration, Oral; Aged; Alendronate; Anti-Bacterial Agents; Bone Density Conservation Agents; Di

2011
How patients' lack of knowledge about oral bisphosphonates can interfere with medical and dental care.
    Journal of the American Dental Association (1939), 2010, Volume: 141, Issue:5

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alendronate; Bone Density; Bone Density Conser

2010
Treatment outcomes in patients with bisphosphonate-related osteonecrosis of the jaws: a prospective study.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2010, Volume: 110, Issue:1

    Topics: Aged; Alcohol Drinking; Alendronate; Anti-Bacterial Agents; Bone Density Conservation Agents; Chroni

2010
Demineralization removes residual alendronate in allograft bone procured from donors with a history of bisphosphonate use.
    Journal of periodontology, 2011, Volume: 82, Issue:2

    Topics: Aged; Alendronate; Bone Demineralization Technique; Bone Density Conservation Agents; Bone Matrix; B

2011
[Jaw osteonecrosis induced by oral biphosphonates: 12 cases].
    Revue de stomatologie et de chirurgie maxillo-faciale, 2010, Volume: 111, Issue:4

    Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Alendronate; Autoimmu

2010
Association between bisphosphonates and jaw osteonecrosis: a study in Wistar rats.
    Head & neck, 2011, Volume: 33, Issue:2

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Diphosphonates; Disease Models, Animal; Drug

2011
Bisphosphonates and atypical femoral fractures.
    The New England journal of medicine, 2010, 09-09, Volume: 363, Issue:11

    Topics: Alendronate; Bone Density Conservation Agents; Bone Resorption; Diphosphonates; Femoral Fractures; H

2010
Nonexposed variant of bisphosphonate-associated osteonecrosis of the jaw: a case series.
    The American journal of medicine, 2010, Volume: 123, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Breast Neoplasms; Dip

2010
Retrospective study of two biochemical markers for the risk assessment of oral bisphosphonate-related osteonecrosis of the jaws: can they be utilized as risk markers?
    Clinical oral implants research, 2011, Volume: 22, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alendronate; Biomarkers; Bone Density Conservation Ag

2011
Teriparatide for bone loss in the jaw.
    The New England journal of medicine, 2010, Dec-16, Volume: 363, Issue:25

    Topics: Alendronate; Bone Density Conservation Agents; Bone Regeneration; Combined Modality Therapy; Humans;

2010
Teriparatide therapy for alendronate-associated osteonecrosis of the jaw.
    The New England journal of medicine, 2010, Dec-16, Volume: 363, Issue:25

    Topics: Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Bone Regeneration; Female; Humans;

2010
Teriparatide therapy for osteonecrosis of the jaw.
    The New England journal of medicine, 2011, 03-17, Volume: 364, Issue:11

    Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Bone Regeneration; Drug Interactions; H

2011
[Prosthetic rehabilitation after osteonecrosis of the jaws due to histiocytosis X and treatment with bisphosphonates apropos of a case].
    Odonto-stomatologie tropicale = Tropical dental journal, 2010, Volume: 33, Issue:132

    Topics: Adult; Alendronate; Bone Density Conservation Agents; Denture Design; Denture, Partial, Fixed; Dentu

2010
Oral bisphosphonate-related osteonecrosis of the jaws in rheumatoid arthritis patients: a critical discussion and two case reports.
    Head & face medicine, 2011, Apr-27, Volume: 7

    Topics: Administration, Oral; Aged; Alendronate; Arthritis, Rheumatoid; Bone Density Conservation Agents; Di

2011
Dental sinus tracts mimicking scrofuloderma: cutaneous presentation of underlying bisphosphonate-related osteonecrosis of the jaw.
    Clinical and experimental dermatology, 2011, Volume: 36, Issue:6

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Cutaneous Fistula; Diagnosis, Differential; Dip

2011
Bisphosphonate-induced osteonecrosis of the jaw.
    The Journal of the Association of Physicians of India, 2011, Volume: 59

    Topics: Adult; Aged; Alendronate; Bone Density Conservation Agents; Female; Humans; Jaw Diseases; Osteonecro

2011
[Inflammation of the jaws during treatment with bisphosphonates].
    Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:41

    Topics: Administration, Oral; Aged; Alendronate; Bone Density; Bone Density Conservation Agents; Bone Diseas

2011
Images in clinical medicine. Halitosis and sensory loss.
    The New England journal of medicine, 2012, Aug-09, Volume: 367, Issue:6

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Female; Halitosis; Humans; Mandibular Diseases;

2012
Treatment of spontaneous osteonecrosis of the knee (SPONK) by a bisphosphonate.
    Acta orthopaedica, 2012, Volume: 83, Issue:5

    Topics: Aged; Aged, 80 and over; Alendronate; Diphosphonates; Female; Humans; Knee Joint; Male; Middle Aged;

2012
Ten years of alendronate treatment for osteoporosis in postmenopausal women.
    The New England journal of medicine, 2004, Jul-08, Volume: 351, Issue:2

    Topics: Alendronate; Bone Regeneration; Female; Humans; Jaw; Osteonecrosis; Osteoporosis, Postmenopausal; Ri

2004
Alendronate prevents collapse in mechanically loaded osteochondral grafts: a bone chamber study in rats.
    Acta orthopaedica Scandinavica, 2004, Volume: 75, Issue:6

    Topics: Alendronate; Animals; Biomechanical Phenomena; Bone Remodeling; Bone Resorption; Bone Transplantatio

2004
Alendronate (Fosamax) and risedronate (Actonel) revisited.
    The Medical letter on drugs and therapeutics, 2005, Apr-25, Volume: 47, Issue:1207

    Topics: Alendronate; Bone Density; Bone Remodeling; Dose-Response Relationship, Drug; Etidronic Acid; Female

2005
Bisphosphonates and avascular necrosis of the jaw: a possible association.
    The Medical journal of Australia, 2005, Apr-18, Volume: 182, Issue:8

    Topics: Aged; Aged, 80 and over; Alendronate; Anti-Inflammatory Agents; Diphosphonates; Female; Follow-Up St

2005
Osteonecrosis of the jaw and bisphosphonates.
    The New England journal of medicine, 2005, Jul-07, Volume: 353, Issue:1

    Topics: Alendronate; Animals; Diphosphonates; Humans; Imidazoles; Jaw Diseases; Osteonecrosis; Osteoporosis;

2005
Bisphosphonate-associated osteonecrosis of the jaws and endodontic treatment: two case reports.
    Journal of endodontics, 2005, Volume: 31, Issue:10

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Diphosphonates; Humans; Imidazoles; Jaw Disease

2005
Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2005, Volume: 63, Issue:11

    Topics: Abscess; Alendronate; Antineoplastic Agents; Bone Density Conservation Agents; Bone Neoplasms; Breas

2005
[Osteonecrosis of the jaws as a possible adverse effect of the use of bisphosphonates].
    Mund-, Kiefer- und Gesichtschirurgie : MKG, 2005, Volume: 9, Issue:4

    Topics: Aged; Alendronate; Diphosphonates; Female; Follow-Up Studies; Humans; Imidazoles; Male; Mandibular D

2005
By the way, doctor. I've heard that taking Fosamax for a long time causes the jawbone to deteriorate. Do you know anything about this?
    Harvard women's health watch, 2005, Volume: 13, Issue:4

    Topics: Alendronate; Bone Density Conservation Agents; Diphosphonates; Female; Humans; Imidazoles; Osteoclas

2005
Relationship between periodontal disease and systemic diseases.
    Texas dental journal, 2006, Volume: 123, Issue:2

    Topics: Alendronate; Bone Density Conservation Agents; Contraindications; Dental Implantation, Endosseous; D

2006
Prosthodontic treatment during active osteonecrosis related to radiation and bisphosphonate therapy: a clinical report.
    The Journal of prosthetic dentistry, 2006, Volume: 96, Issue:1

    Topics: Alendronate; Bone Density Conservation Agents; Carcinoma, Squamous Cell; Cranial Irradiation; Dentur

2006
Osteonecrosis of the jaw and oral bisphosphonate treatment.
    Journal of the American Dental Association (1939), 2006, Volume: 137, Issue:8

    Topics: Administration, Oral; Aged; Alendronate; Bone Density Conservation Agents; Debridement; Dental Carie

2006
[Bisphosphonate-related bilateral mandibular osteochemonecrosis with pathological fracture of the horizontal ramus].
    Revue de stomatologie et de chirurgie maxillo-faciale, 2006, Volume: 107, Issue:5

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Fractures, Spontaneous; Humans; Male; Mandibula

2006
Bisphosphonate-associated osteonecrosis of the jaw in patients with multiple myeloma and breast cancer.
    Acta haematologica, 2007, Volume: 117, Issue:3

    Topics: Alendronate; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Fem

2007
Bone necrosis of the jaws associated with bisphosphonate treatment: a report of twenty-nine cases.
    Acta bio-medica : Atenei Parmensis, 2006, Volume: 77, Issue:2

    Topics: Aged; Aged, 80 and over; Alendronate; Anti-Bacterial Agents; Antifungal Agents; Bone Density Conserv

2006
Clinical concerns of alendronate use.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2007, Volume: 65, Issue:2

    Topics: Alendronate; Bone Density Conservation Agents; Bone Remodeling; Contraindications; Dose-Response Rel

2007
By the way, doctor. I'm 60 and have osteoporosis. My doctor is recommending Fosamax, but I'm concerned about jawbone problems. Are there any other drugs I can take?
    Harvard women's health watch, 2006, Volume: 14, Issue:4

    Topics: Alendronate; Bone Density Conservation Agents; Estrogen Replacement Therapy; Exercise; Female; Human

2006
Resolution of bisphosphonate-associated osteonecrosis of the mandible: possible application for intermittent low-dose parathyroid hormone [rhPTH(1-34)].
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2007, Volume: 65, Issue:3

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Clinical Protocols; Female; Humans; Injections,

2007
[Questions and answers about bisphosphonates].
    Presse medicale (Paris, France : 1983), 2007, Volume: 36, Issue:3 Pt 1

    Topics: Administration, Oral; Age Factors; Alendronate; Bone Density; Bone Density Conservation Agents; Bone

2007
Bisphosphonates. A cornerstone of osteoporosis treatment.
    Mayo Clinic women's healthsource, 2007, Volume: 11, Issue:5

    Topics: Alendronate; Bone Density Conservation Agents; Diphosphonates; Estrogen Replacement Therapy; Etidron

2007
[Advances in the research of bisphosphonate-associated osteonecrosis of the jaws].
    Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2006, Volume: 15, Issue:6

    Topics: Alendronate; Biomedical Research; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density C

2006
Oral bisphosphonate associated osteonecrosis of the jaws: three case reports.
    British dental journal, 2007, Jul-28, Volume: 203, Issue:2

    Topics: Administration, Oral; Aged; Alendronate; Anti-Bacterial Agents; Bone Density Conservation Agents; Bo

2007
Implant placement with or without simultaneous tooth extraction in patients taking oral bisphosphonates: postoperative healing, early follow-up, and the incidence of complications in two private practices.
    Journal of periodontology, 2007, Volume: 78, Issue:9

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Dental

2007
Denture-related osteonecrosis of the maxilla associated with oral bisphosphonate treatment.
    Journal of the American Dental Association (1939), 2007, Volume: 138, Issue:9

    Topics: Administration, Oral; Aged; Alendronate; Bone Density Conservation Agents; Denture, Partial, Removab

2007
Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2007, Volume: 65, Issue:12

    Topics: Alendronate; Biomarkers; Bone Density Conservation Agents; Collagen Type I; Diphosphonates; Etidroni

2007
Comment on: Bisphosphonates and osteonecrosis of the jaw.
    Rheumatology (Oxford, England), 2008, Volume: 47, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Alendronate; Child; Child, Preschool; Diphosphonates; Dose-

2008
Osteonecrosis of the jaw: new developments in an old disease.
    The Journal of rheumatology, 2008, Volume: 35, Issue:4

    Topics: Alendronate; Bone Density Conservation Agents; Diphosphonates; Dose-Response Relationship, Drug; Eti

2008
Mandible matrix necrosis in beagle dogs after 3 years of daily oral bisphosphonate treatment.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2008, Volume: 66, Issue:5

    Topics: Administration, Oral; Alendronate; Analysis of Variance; Animals; Bone Density Conservation Agents;

2008
Bisphosphonate related osteonecrosis of the palate: report of a case managed with free tissue transfer.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2008, Volume: 105, Issue:5

    Topics: Administration, Oral; Aged; Alendronate; Anastomosis, Surgical; Bone Density Conservation Agents; Fe

2008
Clinical concerns of alendronate use.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2008, Volume: 66, Issue:6

    Topics: Adult Stem Cells; Alendronate; Bone Density Conservation Agents; Dose-Response Relationship, Drug; H

2008