Page last updated: 2024-10-22

alendronate and Osteomalacia

alendronate has been researched along with Osteomalacia in 7 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Osteomalacia: Disorder caused by an interruption of the mineralization of organic bone matrix leading to bone softening, bone pain, and weakness. It is the adult form of rickets resulting from disruption of VITAMIN D; PHOSPHORUS; or CALCIUM homeostasis.

Research Excerpts

ExcerptRelevanceReference
"Treatment effects on bone quality and remodeling was assessed in postmenopausal women with osteoporosis treated with oral alendronate."9.08Histomorphometric assessment of the long-term effects of alendronate on bone quality and remodeling in patients with osteoporosis. ( Arlot, ME; Chavassieux, PM; Meunier, PJ; Reda, C; Wei, L; Yates, AJ, 1997)
"Treatment effects on bone quality and remodeling was assessed in postmenopausal women with osteoporosis treated with oral alendronate."5.08Histomorphometric assessment of the long-term effects of alendronate on bone quality and remodeling in patients with osteoporosis. ( Arlot, ME; Chavassieux, PM; Meunier, PJ; Reda, C; Wei, L; Yates, AJ, 1997)
"Osteoporosis and osteomalacia have been observed after gastrectomy and appear to be caused by reduced food intake and absorption, and steatorrhea."2.82Metabolic bone disorders after gastrectomy: inevitable or preventable? ( Aoyama, T; Atsumi, Y; Rino, Y; Yamada, T; Yukawa, N, 2022)
"Alendronate treatment was discontinued and, while a suitable kidney donor was sought, the patient was treated for 6 months with teriparatide, which significantly reduced the osteomalacia."1.42Reversible Deterioration in Hypophosphatasia Caused by Renal Failure With Bisphosphonate Treatment. ( Collins, JF; Cundy, T; Dray, M; Fratzl-Zelman, N; Gamsjaeger, S; Klaushofer, K; Michigami, T; Paschalis, EP; Roschger, A; Roschger, P; Tachikawa, K, 2015)
"Alendronate has been studied extensively by large trials of high quality and its efficacy to reduce the risk of vertebral and nonvertebral fractures is in line with the criteria of evidence-based medicine."1.33[Drug therapy for prevention of falls and fractures]. ( Ringe, JD, 2006)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Rino, Y1
Aoyama, T1
Atsumi, Y1
Yamada, T1
Yukawa, N1
Florez, H1
Mandelikova, S1
Filella, X1
Monegal, A1
GuaƱabens, N1
Peris, P1
Cundy, T1
Michigami, T1
Tachikawa, K1
Dray, M1
Collins, JF1
Paschalis, EP1
Gamsjaeger, S1
Roschger, A1
Fratzl-Zelman, N1
Roschger, P1
Klaushofer, K1
Ghose, R1
Ringe, JD1
Papierska, L1
Rabijewski, M1
Chavassieux, PM1
Arlot, ME1
Reda, C1
Wei, L1
Yates, AJ1
Meunier, PJ1

Reviews

2 reviews available for alendronate and Osteomalacia

ArticleYear
Metabolic bone disorders after gastrectomy: inevitable or preventable?
    Surgery today, 2022, Volume: 52, Issue:2

    Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Calcitriol; F

2022
[Glucocorticoid-induced osteoporosis].
    Polskie Archiwum Medycyny Wewnetrznej, 2007, Volume: 117, Issue:8

    Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Calcium; Diphosphonates; Female; Fractu

2007

Trials

1 trial available for alendronate and Osteomalacia

ArticleYear
Histomorphometric assessment of the long-term effects of alendronate on bone quality and remodeling in patients with osteoporosis.
    The Journal of clinical investigation, 1997, Sep-15, Volume: 100, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Biopsy; Bone and Bones; Bone Remodeling; Calcification,

1997

Other Studies

4 other studies available for alendronate and Osteomalacia

ArticleYear
Clinical significance of increased serum levels of FGF-23 in fibrous dysplasia.
    Medicina clinica, 2018, 07-23, Volume: 151, Issue:2

    Topics: Adult; Aged; Alendronate; Biomarkers; Bone Density Conservation Agents; Female; Fibroblast Growth Fa

2018
Reversible Deterioration in Hypophosphatasia Caused by Renal Failure With Bisphosphonate Treatment.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2015, Volume: 30, Issue:9

    Topics: Alendronate; Densitometry; Diphosphonates; DNA Mutational Analysis; Fractures, Bone; Genetic Associa

2015
Osteomalacia: recovery of bone density.
    The New Zealand medical journal, 2004, Jun-18, Volume: 117, Issue:1196

    Topics: 25-Hydroxyvitamin D 2; Absorptiometry, Photon; Aged; Alendronate; Alkaline Phosphatase; Back Pain; B

2004
[Drug therapy for prevention of falls and fractures].
    Medizinische Klinik (Munich, Germany : 1983), 2006, Volume: 101 Suppl 1

    Topics: Accidental Falls; Alendronate; Bone Density Conservation Agents; Drug Therapy, Combination; Evidence

2006