alendronate has been researched along with Oral Ulcer in 17 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
Oral Ulcer: A loss of mucous substance of the mouth showing local excavation of the surface, resulting from the sloughing of inflammatory necrotic tissue. It is the result of a variety of causes, e.g., denture irritation, aphthous stomatitis (STOMATITIS, APHTHOUS); NOMA; necrotizing gingivitis (GINGIVITIS, NECROTIZING ULCERATIVE); TOOTHBRUSHING; and various irritants. (From Jablonski, Dictionary of Dentistry, 1992, p842)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Irritation of the mucosa of the aerodigestive tract is a well-known adverse effect of alendronate, whereas oral ulceration has been reported in only 14 articles in both the English and non-English literature." | 7.76 | Oral ulcer associated with alendronate: a case report. ( Kharazmi, M; Rizk, M; Sjöqvist, K; Warfvinge, G, 2010) |
| "The authors report the case of a 54-year-old man suffering from steroid-induced osteoporosis, who presented with severe oral ulcerations due to sucking alendronate tablets instead of swallowing them." | 7.70 | Severe oral ulcerations induced by alendronate. ( Bolla, G; Demerjian, N; Spreux, A, 1999) |
| "Alendronate can cause mucosal ulcerations in the oral cavity, affecting patients with intense pain and causing severe morbidity." | 6.48 | Oral ulcers, a little known adverse effect of alendronate: review of the literature. ( Kharazmi, M; Sjöqvist, K; Warfvinge, G, 2012) |
| "Irritation of the mucosa of the aerodigestive tract is a well-known adverse effect of alendronate, whereas oral ulceration has been reported in only 14 articles in both the English and non-English literature." | 3.76 | Oral ulcer associated with alendronate: a case report. ( Kharazmi, M; Rizk, M; Sjöqvist, K; Warfvinge, G, 2010) |
| "The authors report the case of a 54-year-old man suffering from steroid-induced osteoporosis, who presented with severe oral ulcerations due to sucking alendronate tablets instead of swallowing them." | 3.70 | Severe oral ulcerations induced by alendronate. ( Bolla, G; Demerjian, N; Spreux, A, 1999) |
| "Alendronate can cause mucosal ulcerations in the oral cavity, affecting patients with intense pain and causing severe morbidity." | 2.48 | Oral ulcers, a little known adverse effect of alendronate: review of the literature. ( Kharazmi, M; Sjöqvist, K; Warfvinge, G, 2012) |
| " However, there seems to be a limited awareness that oral bisphosphonates can also induce adverse effects in the soft tissues of the oral cavity, as indicated by the paucity of reported cases in the literature." | 1.38 | Pharmacovigilance of oral bisphosphonates: adverse effects manifesting in the soft tissue of the oral cavity. ( Kharazmi, M; Persson, U; Warfvinge, G, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 10 (58.82) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Larson, MJ | 1 |
| Oakes, AB | 1 |
| Epperson, E | 1 |
| Chew, DJ | 1 |
| Lengfeld, J | 1 |
| Buder-Bakhaya, K | 1 |
| Goebeler, M | 1 |
| Wobser, M | 1 |
| Cardona Tortajada, F | 1 |
| Sainz Gómez, E | 1 |
| Figuerido Garmendia, J | 1 |
| Lirón de Robles Adsuar, A | 1 |
| Aleid, W | 1 |
| Sidebottom, A | 1 |
| Barrow, SY | 1 |
| Kharazmi, M | 3 |
| Sjöqvist, K | 2 |
| Rizk, M | 1 |
| Warfvinge, G | 3 |
| Abtahi, J | 1 |
| Agholme, F | 1 |
| Sandberg, O | 1 |
| Aspenberg, P | 1 |
| Persson, U | 1 |
| Krasagakis, K | 1 |
| Krüger-Krasagakis, S | 1 |
| Ioannidou, D | 1 |
| Tosca, A | 1 |
| Schmutz, JL | 1 |
| Barbaud, A | 2 |
| Trechot, P | 2 |
| Ponte Fernández, N | 1 |
| Estefania Fresco, R | 1 |
| Aguirre Urizar, JM | 1 |
| Dicko, A | 1 |
| Toulemonde, A | 1 |
| Hoareau, F | 1 |
| Avenel-Audran, M | 1 |
| Verret, JL | 1 |
| Levin, L | 1 |
| Laviv, A | 1 |
| Schwartz-Arad, D | 1 |
| Demerjian, N | 1 |
| Bolla, G | 1 |
| Spreux, A | 1 |
| Gonzalez-Moles, MA | 1 |
| Bagan-Sebastian, JV | 1 |
| Schmutz, J | 1 |
3 reviews available for alendronate and Oral Ulcer
| Article | Year |
|---|---|
Bisphosphonate-Mediated Oral Ulcers: A Rare Differential Diagnosis of Erosive Oral Lesions.
Topics: Aged; Alendronate; Bone Density Conservation Agents; Diagnosis, Differential; Female; Humans; Oral U | 2016 |
Oral ulcers, a little known adverse effect of alendronate: review of the literature.
Topics: Alendronate; Bone Density Conservation Agents; Drug Monitoring; Humans; Oral Ulcer; Substance-Relate | 2012 |
Bisphosphonates and oral pathology I. General and preventive aspects.
Topics: Administration, Oral; Alendronate; Antibiotic Prophylaxis; Bone Density Conservation Agents; Bone Re | 2006 |
14 other studies available for alendronate and Oral Ulcer
| Article | Year |
|---|---|
Medication-related osteonecrosis of the jaw after long-term bisphosphonate treatment in a cat.
Topics: Alendronate; Animals; Bisphosphonate-Associated Osteonecrosis of the Jaw; Cat Diseases; Cats; Diphos | 2019 |
[Chronic mouth ulcer due to inadequate ingestion of alendronate].
Topics: Aged; Alendronate; Chronic Disease; Female; Humans; Oral Ulcer | 2008 |
Oral mucosal irritation with incorrect use of alendronate.
Topics: Administration, Oral; Alendronate; Bone Density Conservation Agents; Humans; Male; Middle Aged; Oral | 2009 |
Is your knowledge up-to-date? Bisphosphonate-related osteonecrosis of the jaw.
Topics: Aged; Alendronate; Bone Density Conservation Agents; Denture, Complete, Upper; Diphosphonates; Femal | 2008 |
Oral ulcer associated with alendronate: a case report.
Topics: Aged, 80 and over; Alendronate; Atrophy; Biopsy; Bone Density Conservation Agents; Diagnosis, Differ | 2010 |
Bisphosphonate-induced osteonecrosis of the jaw in a rat model arises first after the bone has become exposed. No primary necrosis in unexposed bone.
Topics: Alendronate; Animals; Anti-Inflammatory Agents; Bisphosphonate-Associated Osteonecrosis of the Jaw; | 2012 |
Pharmacovigilance of oral bisphosphonates: adverse effects manifesting in the soft tissue of the oral cavity.
Topics: Administration, Oral; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Alendronate; | 2012 |
Chronic erosive and ulcerative oral lesions caused by incorrect administration of alendronate.
Topics: Aged; Alendronate; Chronic Disease; Female; Humans; Oral Ulcer | 2004 |
[Alendronate and mouth ulcers: careful interrogation of the patient to start with].
Topics: Alendronate; Bone Density Conservation Agents; Humans; Male; Medical History Taking; Middle Aged; Or | 2005 |
[Mouth ulcers].
Topics: Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Esophagitis; Humans; Male; Oral Ul | 2007 |
Denture-related osteonecrosis of the maxilla associated with oral bisphosphonate treatment.
Topics: Administration, Oral; Aged; Alendronate; Bone Density Conservation Agents; Denture, Partial, Removab | 2007 |
Severe oral ulcerations induced by alendronate.
Topics: Alendronate; Humans; Male; Middle Aged; Oral Ulcer; Osteoporosis | 1999 |
Alendronate-related oral mucosa ulcerations.
Topics: Aged; Alendronate; Female; Humans; Lip Diseases; Mouth Mucosa; Oral Ulcer; Palate, Hard; Tongue Dise | 2000 |
[Monosodium alendronate].
Topics: Alendronate; Esophagitis; Humans; Oral Ulcer | 2000 |