alendronate and Myalgia studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Research Excerpts

Excerpt	Relevance	Reference
"A total of 140 postmenopausal women or men aged older than 50 years who met the indications for osteoporosis treatment were randomized to receive either generic (Bonmax®) or brand alendronate (Fosamax®) 70 mg/week over a 12-month period during the May 2014 to June 2015 study period."	9.24	Randomized clinical trial comparing efficacy and safety of brand versus generic alendronate (Bonmax®) for osteoporosis treatment. ( Jarusriwanna, A; Songcharoen, P; Unnanuntana, A, 2017)
"A total of 140 postmenopausal women or men aged older than 50 years who met the indications for osteoporosis treatment were randomized to receive either generic (Bonmax®) or brand alendronate (Fosamax®) 70 mg/week over a 12-month period during the May 2014 to June 2015 study period."	5.24	Randomized clinical trial comparing efficacy and safety of brand versus generic alendronate (Bonmax®) for osteoporosis treatment. ( Jarusriwanna, A; Songcharoen, P; Unnanuntana, A, 2017)

Research

Studies (1)

Authors

Clinical Trials (1)

Trial Overview

Trial Outcomes

Bone Mineral Density (BMD) at Lumbar Spine (L1-L4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Unnanuntana, A	1
Jarusriwanna, A	1
Songcharoen, P	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Randomized Trial Comparing Efficacy and Safety of Brand Versus Generic Alendronate for Osteoporosis Treatment[NCT02371252]	Phase 4	140 participants (Actual)	Interventional	2014-04-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Percent changes of bone mineral density at lumbar spine (L1-L4) from baseline to 1-year after treatment will be compared and analysed between 2 groups. (NCT02371252)
Timeframe: 1 year after treatment

Bone Mineral Density (BMD) at Total Hip

Intervention	percent (Mean)
Original Alendronate (Fosamax)	5.54
Generic Alendronate (Bonmax)	5.39

Percent changes of bone mineral density at total hip from baseline to 1-year after treatment will be compared and analysed between 2 groups. (NCT02371252)
Timeframe: 1 year after treatment

Intervention	percent (Mean)
Original Alendronate (Fosamax)	2.48
Generic Alendronate (Bonmax)	2.52