alendronate has been researched along with Muscular Dystrophies, Limb-Girdle in 1 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
Muscular Dystrophies, Limb-Girdle: A heterogenous group of inherited muscular dystrophy that can be autosomal dominant or autosomal recessive. There are many forms (called LGMDs) involving genes encoding muscle membrane proteins such as the sarcoglycan (SARCOGLYCANS) complex that interacts with DYSTROPHIN. The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the HIPS and SHOULDERS (the pelvic and shoulder girdles).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alendronate treatment did not ameliorate muscle degeneration, but demonstrated a limited enhancement on muscle function test." | 1.43 | Glucocorticoid Steroid and Alendronate Treatment Alleviates Dystrophic Phenotype with Enhanced Functional Glycosylation of α-Dystroglycan in Mouse Model of Limb-Girdle Muscular Dystrophy with FKRPP448L Mutation. ( Blaeser, A; Bollinger, LE; Cox, MD; Harper, AD; Lu, P; Lu, QL; Luckie, TM; Madden, KL; Richardson, SM; Shah, SN; Sparks, S; Sun, Y; Wu, B, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, B | 1 |
| Shah, SN | 1 |
| Lu, P | 1 |
| Richardson, SM | 1 |
| Bollinger, LE | 1 |
| Blaeser, A | 1 |
| Madden, KL | 1 |
| Sun, Y | 1 |
| Luckie, TM | 1 |
| Cox, MD | 1 |
| Sparks, S | 1 |
| Harper, AD | 1 |
| Lu, QL | 1 |
1 other study available for alendronate and Muscular Dystrophies, Limb-Girdle
| Article | Year |
|---|---|
Glucocorticoid Steroid and Alendronate Treatment Alleviates Dystrophic Phenotype with Enhanced Functional Glycosylation of α-Dystroglycan in Mouse Model of Limb-Girdle Muscular Dystrophy with FKRPP448L Mutation.
Topics: Adrenal Cortex Hormones; Alendronate; Animals; Blotting, Western; Bone Density; Bone Density Conserv | 2016 |