Page last updated: 2024-10-22

alendronate and Metastase

alendronate has been researched along with Metastase in 6 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Research Excerpts

ExcerptRelevanceReference
"1 mg/kg twice weekly or weekly) and dosing along with taxol (10-50 mg/kg/day, twice weekly, or weekly) blocked the growth of PC-3 ML tumors in the bone marrow and soft tissues in a statistically significant manner and improved survival rates significantly (p < 0."5.29Effects of alendronate and taxol on PC-3 ML cell bone metastases in SCID mice. ( Stearns, ME; Wang, M, 1996)
"The various features of carcinoid tumors metastasizing to the skeleton are briefly reviewed."1.31Case of an ivory vertebra. ( Ball, DW; Basaria, S; Belzberg, AJ; McCarthy, EF, 2000)
"1 mg/kg twice weekly or weekly) and dosing along with taxol (10-50 mg/kg/day, twice weekly, or weekly) blocked the growth of PC-3 ML tumors in the bone marrow and soft tissues in a statistically significant manner and improved survival rates significantly (p < 0."1.29Effects of alendronate and taxol on PC-3 ML cell bone metastases in SCID mice. ( Stearns, ME; Wang, M, 1996)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aragon-Ching, JB1
Ning, YM1
Chen, CC1
Latham, L1
Guadagnini, JP1
Gulley, JL1
Arlen, PM1
Wright, JJ1
Parnes, H1
Figg, WD1
Dahut, WL1
Thamake, SI1
Raut, SL1
Gryczynski, Z1
Ranjan, AP1
Vishwanatha, JK1
Ozen, M1
Karaahmet, F1
Aydin, K1
Sarici, F1
Altundag, K1
Stearns, ME1
Wang, M1
Basaria, S1
McCarthy, EF1
Belzberg, AJ1
Ball, DW1
Andela, VB1
Rosenblatt, JD1
Schwarz, EM1
Puzas, EJ1
O'Keefe, RJ1
Rosier, RN1

Trials

1 trial available for alendronate and Metastase

ArticleYear
Higher incidence of Osteonecrosis of the Jaw (ONJ) in patients with metastatic castration resistant prostate cancer treated with anti-angiogenic agents.
    Cancer investigation, 2009, Volume: 27, Issue:2

    Topics: Adult; Aged; Alendronate; Angiogenesis Inhibitors; Diphosphonates; Humans; Ibandronic Acid; Incidenc

2009

Other Studies

5 other studies available for alendronate and Metastase

ArticleYear
Alendronate coated poly-lactic-co-glycolic acid (PLGA) nanoparticles for active targeting of metastatic breast cancer.
    Biomaterials, 2012, Volume: 33, Issue:29

    Topics: Alendronate; Animals; Antineoplastic Agents; Bone and Bones; Bone Neoplasms; Boronic Acids; Bortezom

2012
Bisphosphonates may also be effective in the management of non-skeletal metastases in hormone receptor positive breast cancer.
    Medical hypotheses, 2007, Volume: 68, Issue:3

    Topics: Alendronate; Breast Neoplasms; Diphosphonates; Female; Humans; Neoplasm Metastasis; Receptors, Estro

2007
Effects of alendronate and taxol on PC-3 ML cell bone metastases in SCID mice.
    Invasion & metastasis, 1996, Volume: 16, Issue:3

    Topics: Alendronate; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protoc

1996
Case of an ivory vertebra.
    Journal of endocrinological investigation, 2000, Volume: 23, Issue:8

    Topics: Alendronate; Alkaline Phosphatase; Biopsy; Bone Marrow; Carcinoid Tumor; Diagnosis, Differential; Di

2000
Synergism of aminobisphosphonates and farnesyl transferase inhibitors on tumor metastasis.
    Clinical orthopaedics and related research, 2002, Issue:397

    Topics: Alendronate; Alkyl and Aryl Transferases; Animals; Drug Screening Assays, Antitumor; Drug Synergism;

2002