Page last updated: 2024-10-22

alendronate and Leishmaniasis, Visceral

alendronate has been researched along with Leishmaniasis, Visceral in 1 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Leishmaniasis, Visceral: A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African.

Research Excerpts

ExcerptRelevanceReference
"Alendronate was essentially inactive against both parasites."1.31In vivo activities of farnesyl pyrophosphate synthase inhibitors against Leishmania donovani and Toxoplasma gondii. ( Araujo, FG; Croft, SL; Docampo, R; Khan, AA; Martin, MB; Moreno, SN; Oldfield, E; Slifer, TR; Yardley, V, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yardley, V1
Khan, AA1
Martin, MB1
Slifer, TR1
Araujo, FG1
Moreno, SN1
Docampo, R1
Croft, SL1
Oldfield, E1

Other Studies

1 other study available for alendronate and Leishmaniasis, Visceral

ArticleYear
In vivo activities of farnesyl pyrophosphate synthase inhibitors against Leishmania donovani and Toxoplasma gondii.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:3

    Topics: Administration, Oral; Alendronate; Alkyl and Aryl Transferases; Animals; Cricetinae; Diphosphonates;

2002