alendronate has been researched along with Hypocalcemia in 11 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
Hypocalcemia: Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to assess the effects of the antiresorptive treatments of alendronate (ALN), risedronate (RIS) and raloxifene (RLX) on the response of bone to endogenous parathyroid hormone (PTH) induced by acute hypocalcemia." | 5.14 | Marked reduction of bone turnover by alendronate attenuates the acute response of bone resorption marker to endogenous parathyroid hormone. ( Stepan, JJ; Zikan, V, 2009) |
| "Alendronate sodium is an aminobiphosphonate, an analog of inorganic pyrophosphate, indicated for the treatment of osteoporosis in post-menopausal women." | 3.72 | Pharmacovigilance study of alendronate in England. ( Biswas, PN; Shakir, SA; Wilton, LV, 2003) |
| "This case report describes a patient who was previously prescribed alendronate (Fosamax) and presented with postoperative hypophosphatemia and hypocalcemic tetany after bowel preparation with Fleet Phospho-Soda." | 3.70 | Postoperative hypocalcemic tetany caused by fleet phospho-soda preparation in a patient taking alendronate sodium: report of a case. ( Badhwar, V; Campisi, P; Morin, S; Trudel, JL, 1999) |
| "Alendronate is a bisphosphonate which inhibits bone resorption." | 1.29 | Effects of the bisphosphonate, alendronate, on parturition in the rat. ( Manson, JM; Minsker, DH; Peter, CP, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zikan, V | 1 |
| Stepan, JJ | 1 |
| Jain, SK | 1 |
| Roy, SP | 1 |
| Nagi, ON | 1 |
| Maclsaac, RJ | 1 |
| Seeman, E | 1 |
| Jerums, G | 1 |
| Biswas, PN | 1 |
| Wilton, LV | 1 |
| Shakir, SA | 1 |
| Lin, JH | 1 |
| Chen, IW | 1 |
| deLuna, FA | 1 |
| Hichens, M | 1 |
| Minsker, DH | 1 |
| Manson, JM | 1 |
| Peter, CP | 1 |
| Schussheim, DH | 1 |
| Jacobs, TP | 1 |
| Silverberg, SJ | 1 |
| Ikeda, K | 1 |
| Kawaguchi, Y | 1 |
| Nakayama, M | 1 |
| Yamamoto, H | 1 |
| Osaka, N | 1 |
| Takeyama, H | 1 |
| Hosoya, T | 1 |
| Campisi, P | 1 |
| Badhwar, V | 1 |
| Morin, S | 1 |
| Trudel, JL | 1 |
| Kashyap, AS | 1 |
| Kashyap, S | 1 |
| Stuckey, BG | 1 |
| Lim, EM | 1 |
| Kent, GN | 1 |
| Ward, LC | 1 |
| Gutteridge, DH | 1 |
1 trial available for alendronate and Hypocalcemia
| Article | Year |
|---|---|
Marked reduction of bone turnover by alendronate attenuates the acute response of bone resorption marker to endogenous parathyroid hormone.
Topics: Aged; Aged, 80 and over; Alendronate; Area Under Curve; Biomarkers; Bone Density Conservation Agents | 2009 |
10 other studies available for alendronate and Hypocalcemia
| Article | Year |
|---|---|
Alendronate induced femur fracture complicated with secondary hyperparathyroidism.
Topics: Aged; Alendronate; Bone Density Conservation Agents; Female; Femoral Fractures; Humans; Hyperparathy | 2011 |
Seizures after alendronate.
Topics: Aged; Aged, 80 and over; Alendronate; Drug Administration Schedule; Female; Humans; Hypocalcemia; Os | 2002 |
Pharmacovigilance study of alendronate in England.
Topics: Adult; Aged; Aged, 80 and over; Alendronate; Angioedema; Cohort Studies; Erythema Multiforme; Family | 2003 |
Role of calcium in plasma protein binding and renal handling of alendronate in hypo- and hypercalcemic rats.
Topics: Alendronate; Animals; Blood Proteins; Calcium; Calcium Radioisotopes; Diphosphonates; Hydrogen-Ion C | 1993 |
Effects of the bisphosphonate, alendronate, on parturition in the rat.
Topics: Alendronate; Animals; Calcium; Diphosphonates; Female; Fertility; Hypocalcemia; Labor, Obstetric; Ma | 1993 |
Hypocalcemia associated with alendronate.
Topics: Aged; Alendronate; Bone Diseases, Metabolic; Female; Humans; Hypocalcemia; Hypoparathyroidism | 1999 |
Novel usage of alendronate to prevent profound hypocalcemia immediately after parathyroidectomy in patients with severe secondary hyperparathyroidism.
Topics: Alendronate; Calcium; Humans; Hyperparathyroidism, Secondary; Hypocalcemia; Male; Middle Aged; Parat | 1999 |
Postoperative hypocalcemic tetany caused by fleet phospho-soda preparation in a patient taking alendronate sodium: report of a case.
Topics: Adult; Alendronate; Cathartics; Colectomy; Colonoscopy; Crohn Disease; Drug Combinations; Enema; Fem | 1999 |
Hypoparathyroidism unmasked by alendronate.
Topics: Aged; Alendronate; Calcitriol; Calcium Carbonate; Calcium Channel Agonists; Female; Humans; Hypocalc | 2000 |
Bisphosphonate therapy for Paget's disease in a patient with hypoparathyroidism: profound hypocalcemia, rapid response, and prolonged remission.
Topics: Alendronate; Calcitriol; Calcium; Cervical Vertebrae; Diphosphonates; Female; Humans; Hypocalcemia; | 2001 |