alendronate has been researched along with Hypertrophy in 3 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with alendronate, pamidronate, and zoledronate, but not clodronate, led to a decrease in the number of chondrocytes per column in the hypertrophic chondrocyte layer." | 1.40 | Effect of bisphosphonates on the rapidly growing male murine skeleton. ( Bouxsein, ML; Brooks, DJ; Demay, MB; Louis, L; Zhu, ED, 2014) |
| "Alendronate was injected subcutaneously every other day in postnatal Day 1 Sprague Dawley rats." | 1.36 | Alendronate affects cartilage resorption by regulating vascular endothelial growth factor expression in rats. ( Choi, NK; Jung, JY; Kang, JH; Kang, SJ; Kim, BY; Kim, MS; Kim, SH; Kim, WJ; Ko, HM; Koh, JT; Oh, WM; Yang, SY, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, ED | 1 |
| Louis, L | 1 |
| Brooks, DJ | 1 |
| Bouxsein, ML | 1 |
| Demay, MB | 1 |
| Ye, Y | 1 |
| Hu, SJ | 1 |
| Li, L | 1 |
| Kang, JH | 1 |
| Choi, NK | 1 |
| Kang, SJ | 1 |
| Yang, SY | 1 |
| Ko, HM | 1 |
| Jung, JY | 1 |
| Kim, MS | 1 |
| Koh, JT | 1 |
| Kim, WJ | 1 |
| Oh, WM | 1 |
| Kim, BY | 1 |
| Kim, SH | 1 |
3 other studies available for alendronate and Hypertrophy
| Article | Year |
|---|---|
Effect of bisphosphonates on the rapidly growing male murine skeleton.
Topics: Alendronate; Animals; Apoptosis; Biomechanical Phenomena; Bone and Bones; Bone Development; Bone Res | 2014 |
Inhibition of farnesylpyrophosphate synthase prevents angiotensin II-induced hypertrophic responses in rat neonatal cardiomyocytes: involvement of the RhoA/Rho kinase pathway.
Topics: Alendronate; Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Dimethylallyltranstransferase; | 2009 |
Alendronate affects cartilage resorption by regulating vascular endothelial growth factor expression in rats.
Topics: Alendronate; Animals; Animals, Newborn; Blood Vessels; Bone Density Conservation Agents; Bone Develo | 2010 |