Page last updated: 2024-10-22

alendronate and Gastritis

alendronate has been researched along with Gastritis in 5 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Gastritis: Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders.

Research Excerpts

ExcerptRelevanceReference
"The anti-catabolic bisphosphonate alendronate is considered as the first-line medical treatment in post-menopausal osteoporosis; but several side effects, including gastric mucosal injury, are associated with its use."7.91Melatonin supports alendronate in preserving bone matrix and prevents gastric inflammation in ovariectomized rats. ( Akkiprik, M; Çilingir-Kaya, ÖT; Ercan, F; Gürler, EB; Peker Eyüboglu, I; Reiter, RJ; Yegen, BÇ, 2019)
"The anti-catabolic bisphosphonate alendronate is considered as the first-line medical treatment in post-menopausal osteoporosis; but several side effects, including gastric mucosal injury, are associated with its use."3.91Melatonin supports alendronate in preserving bone matrix and prevents gastric inflammation in ovariectomized rats. ( Akkiprik, M; Çilingir-Kaya, ÖT; Ercan, F; Gürler, EB; Peker Eyüboglu, I; Reiter, RJ; Yegen, BÇ, 2019)
"Alendronate does not cause predictable esophageal, gastric, or duodenal mucosal damage when used as directed."2.69Upper gastrointestinal toxicity of alendronate. ( Depew, WT; Lowe, CE; Meddings, JB; Paterson, WG; Vanner, SJ, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gürler, EB1
Çilingir-Kaya, ÖT1
Peker Eyüboglu, I1
Ercan, F1
Akkiprik, M1
Reiter, RJ1
Yegen, BÇ1
Naito, Y1
Yoshikawa, T1
Parfitt, JR1
Driman, DK1
Downs, RW1
Bone, HG1
McIlwain, H1
Baker, MZ1
Yates, AJ1
Lombardi, A1
Krupa, D1
Harning, R1
Lowe, CE1
Depew, WT1
Vanner, SJ1
Paterson, WG1
Meddings, JB1

Reviews

1 review available for alendronate and Gastritis

ArticleYear
Pathological effects of drugs on the gastrointestinal tract: a review.
    Human pathology, 2007, Volume: 38, Issue:4

    Topics: Alendronate; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Colitis; Drug-Related Side Effects

2007

Trials

2 trials available for alendronate and Gastritis

ArticleYear
An open-label extension study of alendronate treatment in elderly women with osteoporosis.
    Calcified tissue international, 1999, Volume: 64, Issue:6

    Topics: Absorptiometry, Photon; Administration, Oral; Aged; Aged, 80 and over; Alendronate; Bone Density; Do

1999
Upper gastrointestinal toxicity of alendronate.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:3

    Topics: Adult; Aged; Alendronate; Double-Blind Method; Dyspepsia; Female; Gastric Mucosa; Gastritis; Gastros

2000

Other Studies

2 other studies available for alendronate and Gastritis

ArticleYear
Melatonin supports alendronate in preserving bone matrix and prevents gastric inflammation in ovariectomized rats.
    Cell biochemistry and function, 2019, Volume: 37, Issue:2

    Topics: Alendronate; Animals; Bone Matrix; Female; Gastritis; Inflammation; Melatonin; Osteoporosis; Ovariec

2019
Rebamipide: a gastrointestinal protective drug with pleiotropic activities.
    Expert review of gastroenterology & hepatology, 2010, Volume: 4, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Alendronate; Allopurinol; Animals; Anti-Inflammatory Agents

2010