Page last updated: 2024-10-22

alendronate and Fracture, Pathologic

alendronate has been researched along with Fracture, Pathologic in 107 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Research Excerpts

ExcerptRelevanceReference
" The objective of this study was to address the possibility that treatment with alendronate and vitamin D2 may reduce the incidence of hip fractures in elderly women with PD."5.12Alendronate and vitamin D2 for prevention of hip fracture in Parkinson's disease: a randomized controlled trial. ( Iwamoto, J; Kanoko, T; Sato, Y; Satoh, K, 2006)
" The fractures were associated with 6 years of oral alendronate treatment immediately followed by subcutaneous denosumab therapy and later teriparatide therapy for osteoporosis."5.01Antiresorptive-associated spontaneous fractures of both tibiae, followed by an atypical femur fracture during the sequential treatment with alendronate, denosumab then teriparatide. ( Poole, K; Sano, H; Tan, J, 2019)
"Alendronate and risedronate have been the standard regimens in the pharmacological intervention of osteoporosis based on their accumulated evidences of fracture prevention."4.85[New development in bisphosphonate treatment. Fracture prevention by bisphosphonates]. ( Hosoi, T, 2009)
" In Japan, at present, only weekly alendronate and risedronate, both oral, have been approved for osteoporosis."4.85[New development in bisphosphonate treatment. Characteristics and effectiveness of intermittent bisphophonates]. ( Okazaki, R, 2009)
" We performed additional analyses of phase III clinical trial and compared the effect of minodronic acid hydrate on bone turnover markers with those of alendronate in primary osteoporosis."4.85[New development in bisphosphonate treatment. Review of effect on bone metabolism by minodronic acid in primary osteoporosis]. ( Fukunaga, M, 2009)
"We studied 26,636 new users of an osteoporosis medication (alendronate, calcitonin, estrogen, raloxifene, or risedronate) who were age 65 or older and had an extended lapse in refill compliance, defined as a period of at least 60 days after the completion of one prescription in which no refill for any osteoporosis medication was obtained."3.74Gaps in treatment among users of osteoporosis medications: the dynamics of noncompliance. ( Arnold, M; Avorn, J; Brookhart, MA; Finkelstein, JS; Katz, JN; Mogun, H; Patrick, AR; Polinski, JM; Solmon, DH, 2007)
"Alendronate treatment is estimated to result in increases in hip bone density >or=0."2.74Value of routine monitoring of bone mineral density after starting bisphosphonate treatment: secondary analysis of trial data. ( Bauer, DC; Bell, KJ; Craig, JC; Ensrud, K; Hayen, A; Irwig, L; Macaskill, P, 2009)
"Gorham's disease is progressive in most patients; yet it can be self-limiting in a few reported cases."2.53Novel approach of treating Gorham-Stout disease in the humerus--Case report and review of literature. ( Al-Hussaini, M; Attili, A; Ellati, R; Haddad, H; Shehadeh, A, 2016)
" Also reviewed are results of "bridging" studies designed to demonstrate the comparable efficacy of less frequent dosing regimens to increase bone mineral density and to reduce bone turnover."2.45Efficacy of bisphosphonates in reducing fracture risk in postmenopausal osteoporosis. ( Bilezikian, JP, 2009)
" The potent bisphosphonate zoledronate can be given at intervals of as long as 1 year and produces changes in bone density and in markers of bone turnover comparable with those seen with conventional daily oral dosing with alendronate or risedronate."2.42Bisphosphonates: new indications and methods of administration. ( Reid, IR, 2003)
"Food and Drug Administration for the treatment of postmenopausal osteoporosis include the bisphosphonates risedronate and alendronate; the selective estrogen receptor modulator, raloxifene; and intranasal calcitonin-salmon spray."2.42An approach to postmenopausal osteoporosis treatment: a case study review. ( Kessenich, C, 2003)
" Alternative dosing schedules and routes of administration have become available and may improve fracture protection, compliance, and tolerability for the long term treatment of a chronic condition such as osteoporosis."2.42Oral antiresorptive therapy. ( Hosking, DJ; Pande, I, 2004)
"Osteoporosis is a common complication of Cushing's disease/syndrome."2.41Osteoporotic fractures at presentation of Cushing's disease: two case reports and a literature review. ( Crouzet, J; Fournier, JJ; Khanine, V; Luton, JP; Requeda, E; Simon, F, 2000)
"She had been treated for postmenopausal osteoporosis with 70 mg of alendronate weekly for 2 years."1.91A Case Report of Oral Bisphosphonate Treatment for Osteoporosis Leading to Atypical Femoral Fracture and Pathologic Mandibular Fracture. ( Fernandes, TL; Franco, GCN; Jitumori, C; Viezzer Fernandes, B, 2023)
"There are very few cases of pathological fracture induced by pancreatitis that affect the vertebrae."1.37Pathological fracture due to vertebral osteonecrosis associated with pancreatitis. ( Baba, T; Kaneko, H; Shitoto, K; Yoshioka, C, 2011)
"Gorham-Stout disease, or massive osteolysis, is an extremely rare idiopathic condition characterized by spontaneous, localized relentless resorption of one or several contiguous bones."1.36Conservative treatment of a pathologic fracture in a patient with Gorham-Stout disease. ( McCain, JP; Pedroletti, F; Rangarajan, S; Velez, I, 2010)
"Histopathologic analysis revealed a parathyroid adenoma."1.36Primary hyperparathyroidism with classic and severe skeletal involvement. ( Paz-Pacheco, E; Sandoval, MA, 2010)
" Strategies to improve adherence to osteoporosis therapy include reducing dosing frequency, changing the route of administration, educating the patient about optimum bisphosphonate administration, and sending patient reminders."1.35Maximizing effectiveness of bisphosphonate therapy for osteoporosis. ( Martens, MG; Shaw, H, 2008)
"A total of 196 consecutive patients treated for distal radius fractures were included in this study."1.35Comparison of radiographic fracture healing in the distal radius for patients on and off bisphosphonate therapy. ( Ayogu, N; Bouxsein, ML; Chacko, AT; Rozental, TD; Vazquez, MA, 2009)
" The hypothesis of a negative pharmacodynamic interaction between bisphosphonates, PPIs and corticosteroids which could lead to a decrease in bone strength after long-term use needs further investigation."1.35Low-energy femoral fractures associated with the long-term use of bisphosphonates: a case series from a Swiss university hospital. ( Dayer, P; Desmeules, J; Ing-Lorenzini, K; Peter, R; Plachta, O; Suva, D, 2009)
"Treatment with alendronate (Fosamax) reduces the risk of osteoporotic fractures at the spine, hip and wrist in women with and without prevalent vertebral fracture."1.34Cost-effectiveness of alendronate in the treatment of postmenopausal women in 9 European countries--an economic evaluation based on the fracture intervention trial. ( Boonen, S; Borgström, F; Haentjens, P; Johnell, O; Kanis, JA; Sen, SS; Ström, O, 2007)
"Alendronate has been studied extensively by large trials of high quality and its efficacy to reduce the risk of vertebral and nonvertebral fractures is in line with the criteria of evidence-based medicine."1.33[Drug therapy for prevention of falls and fractures]. ( Ringe, JD, 2006)
"Alendronate was significantly more effective than risedronate, calcitonin, estrogen, etidronate, and raloxifene (Relative Risks: 0."1.32Putting evidence-based medicine into clinical practice: comparing anti-resorptive agents for the treatment of osteoporosis. ( Hochberg, MC; Hosking, D; Wehren, LE, 2004)
"Because on bone marker measurement bone resorption was increased and bone formation was decreased from baseline, treatment was switched to oral alendronate (5 mg/day, daily)."1.31Insufficiency fracture of the femoral neck during osteoporosis treatment: a case report. ( Iwamoto, J; Takeda, T, 2002)

Research

Studies (107)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (8.41)18.2507
2000's75 (70.09)29.6817
2010's22 (20.56)24.3611
2020's1 (0.93)2.80

Authors

AuthorsStudies
Fernandes, TL1
Viezzer Fernandes, B1
Jitumori, C1
Franco, GCN1
Mathonet, PY1
Willems, S1
Ciornohac, JF1
Tan, J1
Sano, H1
Poole, K1
Skoglund, K1
Hjortdal, O1
Ellati, R1
Attili, A1
Haddad, H1
Al-Hussaini, M1
Shehadeh, A1
Paccou, J1
Sánchez, A1
Blanco, R1
Martens, MG1
Shaw, H1
Ofluoglu, O1
Ofluoglu, D1
Holder, KK1
Kerley, SS1
Hosoi, T1
Okazaki, R1
Yamaguchi, T1
Sugimoto, T1
Fukunaga, M1
Bilezikian, JP1
Eiken, PA2
Abrahamsen, B1
Rozental, TD1
Vazquez, MA1
Chacko, AT1
Ayogu, N1
Bouxsein, ML1
Harada, A2
Kuroda, T1
Miyakawa, N1
Miyazaki, T1
Shiraki, M2
Wongchuensoontorn, C1
Liebehenschel, N1
Wagner, K1
Fakler, O1
Gutwald, R1
Schmelzeisen, R1
Sauerbier, S1
Bell, KJ1
Hayen, A1
Macaskill, P1
Irwig, L1
Craig, JC1
Ensrud, K2
Bauer, DC1
Ali, T1
Jay, RH1
Asano, S1
Suzuki, A1
Itoh, M1
Ing-Lorenzini, K1
Desmeules, J1
Plachta, O1
Suva, D1
Dayer, P1
Peter, R1
Pedroletti, F1
Rangarajan, S1
McCain, JP1
Velez, I1
Gorai, I1
Hori, H1
Baba, T1
Shitoto, K1
Yoshioka, C1
Kaneko, H1
Kuijpers, SC1
van Roessel, EW1
van Merkesteyn, JP1
Scoletta, M1
Arduino, PG1
Dalmasso, P1
Broccoletti, R1
Mozzati, M1
Gallego, L1
Junquera, L1
Pelaz, A1
Costilla, S1
Ott, SM1
Soen, S1
Wang, K1
Moaveni, A1
Dowrick, A1
Liew, S1
Unnanuntana, A2
Ashfaq, K1
Ton, QV1
Kleimeyer, JP1
Lane, JM3
Rebolledo, BJ1
Rasmussen, M1
Lange, J1
González López-Valcárcel, B1
Sosa Henríquez, M1
Ghazali, N1
Collyer, JC1
Tighe, JV1
Sandoval, MA1
Paz-Pacheco, E1
Robinson, PJ1
Bell, RJ1
Lanzafame, A1
Segal, L1
Kirby, C1
Piterman, L1
Davis, SR1
McCarthy, EA1
Raggio, CL1
Hossack, MD1
Miller, EA1
Jain, S1
Boskey, AL1
Camacho, NP1
Heijckmann, AC1
Juttmann, JR1
Wolffenbuttel, BH1
Iwamoto, J2
Takeda, T1
Reid, IR1
Nakamura, T1
Brixen, KT1
Mosekilde, L2
Jönsson, L1
Borgström, F2
Zethraeus, N1
Kessenich, C1
Lamy, O1
Krieg, MA1
Curković, B1
Wehren, LE2
Hosking, D1
Hochberg, MC2
Mazanec, D1
Siris, ES1
Chen, YT1
Abbott, TA1
Barrett-Connor, E2
Miller, PD1
Berger, ML1
Adachi, JD1
Woo, A1
Hittell, J1
Beardsley, C1
Noh, C1
Stoukides, CA1
Kaul, AF1
Bartl, R1
Ringe, JD2
Orimo, H1
Delmas, PD1
McClung, M1
Pande, I1
Hosking, DJ1
Christoffersen, H1
Holmegaard, SN1
Sato, Y1
Kanoko, T1
Satoh, K1
Kabi, F1
Mkinsi, O1
Zrigui, J1
Wong, P1
Anpalahan, M1
Yamamoto, S1
Kurato, S1
Iwase, T1
Inoue, K1
Sasaki, Y1
Tanaka, T1
Fujita, M1
Nakano, T1
Ando, F1
Vestergaard, P1
Langdahl, B1
Talbi, M1
Carrie, F1
Meley, M1
Briot, K1
Trémollières, F1
Thomas, T1
Roux, C1
Ström, O1
Sen, SS1
Boonen, S1
Haentjens, P1
Johnell, O2
Kanis, JA1
Brookhart, MA1
Avorn, J1
Katz, JN1
Finkelstein, JS1
Arnold, M1
Polinski, JM1
Patrick, AR1
Mogun, H1
Solmon, DH1
Gold, DT1
Martin, BC1
Frytak, JR1
Amonkar, MM1
Cosman, F1
Epstein, S1
Papierska, L1
Rabijewski, M1
Wells, GA1
Cranney, A1
Peterson, J1
Boucher, M1
Shea, B1
Robinson, V1
Coyle, D1
Tugwell, P1
Häuselmann, HJ1
Cummings, SR3
Kopjar, B1
Bjørndal, A1
Downs, RW1
Bone, HG1
McIlwain, H1
Baker, MZ1
Yates, AJ1
Lombardi, A1
Krupa, D1
Harning, R1
Ross, PD1
Black, D1
Genant, HK2
Nevitt, MC1
Musliner, T1
Thompson, D1
Høiseth, A1
el Maghraoui, A1
Lecoules, S1
Lechevalier, D1
Magnin, J1
Eulry, F1
Klovning, A1
Norheim, OF1
Khanine, V1
Fournier, JJ1
Requeda, E1
Luton, JP1
Simon, F1
Crouzet, J1
Kaufman, JM1
Abadie, E1
Adami, S2
Audran, M1
Avouac, B1
Sedrine, WB1
Calvo, G1
Devogelaer, JP1
Fuchs, V1
Kreutz, G1
Nilsson, P1
Pols, H1
Ringe, J1
Van Haelst, L1
Reginster, JY1
Khan, SN1
O'Connor, WJ1
Nydick, M1
Hommen, JP1
Schneider, R1
Tomin, E1
Brand, J1
Curtin, J1
Harsch, IA1
Hübner, RH1
Hahn, EG1
Hensen, J1
Prizzi, R1
Colapietro, F1
Kruse, HP1
Karpf, DB1
Harris, F1
LaCroix, AZ1
Black, DM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A 5-year, Double-blind, Randomized, Placebo-controlled Extension Study to Examine the Long-term Safety and Efficacy of Oral Alendronate in Postmenopausal Women Who Previously Received Alendronate in Conjunction With the Fracture Intervention Trial[NCT00398931]Phase 31,099 participants (Actual)Interventional1998-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

29 reviews available for alendronate and Fracture, Pathologic

ArticleYear
Antiresorptive-associated spontaneous fractures of both tibiae, followed by an atypical femur fracture during the sequential treatment with alendronate, denosumab then teriparatide.
    BMJ case reports, 2019, Jul-23, Volume: 12, Issue:7

    Topics: Absorptiometry, Photon; Adult; Alendronate; Bone Density; Denosumab; Dose-Response Relationship, Dru

2019
Novel approach of treating Gorham-Stout disease in the humerus--Case report and review of literature.
    European review for medical and pharmacological sciences, 2016, Volume: 20, Issue:3

    Topics: Adolescent; Alendronate; Bone Density Conservation Agents; Combined Modality Therapy; Fracture Fixat

2016
Alendronate for fracture prevention in postmenopause.
    American family physician, 2008, Sep-01, Volume: 78, Issue:5

    Topics: Alendronate; Bone Density Conservation Agents; Female; Fractures, Spontaneous; Humans; Middle Aged;

2008
[New development in bisphosphonate treatment. Fracture prevention by bisphosphonates].
    Clinical calcium, 2009, Volume: 19, Issue:1

    Topics: Alendronate; Bone Density Conservation Agents; Diphosphonates; Drug Therapy, Combination; Evidence-B

2009
[New development in bisphosphonate treatment. Characteristics and effectiveness of intermittent bisphophonates].
    Clinical calcium, 2009, Volume: 19, Issue:1

    Topics: Alendronate; Bone Density Conservation Agents; Clinical Trials as Topic; Diphosphonates; Drug Admini

2009
[New development in bisphosphonate treatment. When and how long should patients take bisphosphonates for osteoporosis?].
    Clinical calcium, 2009, Volume: 19, Issue:1

    Topics: Alendronate; Animals; Bone and Bones; Bone Density; Bone Density Conservation Agents; Drug Administr

2009
[New development in bisphosphonate treatment. Review of effect on bone metabolism by minodronic acid in primary osteoporosis].
    Clinical calcium, 2009, Volume: 19, Issue:1

    Topics: Alendronate; Amino Acids; Biomarkers; Bone and Bones; Bone Density Conservation Agents; Clinical Tri

2009
Efficacy of bisphosphonates in reducing fracture risk in postmenopausal osteoporosis.
    The American journal of medicine, 2009, Volume: 122, Issue:2 Suppl

    Topics: Alendronate; Bone Density Conservation Agents; Diphosphonates; Etidronic Acid; Female; Fractures, Sp

2009
[Alendronate for the prevention and treatment of postmenopausal osteoporosis. A survey of a Cochrane review].
    Ugeskrift for laeger, 2009, Mar-09, Volume: 171, Issue:11

    Topics: Alendronate; Bone Density Conservation Agents; Evidence-Based Medicine; Female; Fractures, Spontaneo

2009
[Alendronate for treatment of osteoporoses].
    Nihon rinsho. Japanese journal of clinical medicine, 2009, Volume: 67, Issue:5

    Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Evidence-Based Medicine; Femoral Fractu

2009
[A-TOP research group/JOINT program].
    Nihon rinsho. Japanese journal of clinical medicine, 2009, Volume: 67, Issue:5

    Topics: Alendronate; Bone Density Conservation Agents; Cholecalciferol; Drug Therapy, Combination; Evidence-

2009
[Biochemical markers of bone turnover. New aspect. Biochemical markers of bone turnover in long term treatment with bisphosphonate].
    Clinical calcium, 2009, Volume: 19, Issue:8

    Topics: Alendronate; Biomarkers; Bone and Bones; Bone Density Conservation Agents; Bone Remodeling; Diphosph

2009
[Effects of SERMs on bone health. Combination therapy with raloxifene].
    Clinical calcium, 2010, Volume: 20, Issue:3

    Topics: Alendronate; Bone Density Conservation Agents; Drug Therapy, Combination; Female; Fractures, Spontan

2010
[Measurement of bone mineral density is necessary for monitoring of bisphosphonate treatment].
    Clinical calcium, 2011, Volume: 21, Issue:1

    Topics: Alendronate; Biomarkers; Bone Density; Diphosphonates; Drug Monitoring; Fractures, Spontaneous; Huma

2011
Canadian consensus on osteoporosis. Preventing osteoporosis among postmenopausal women.
    Canadian family physician Medecin de famille canadien, 2003, Volume: 49

    Topics: Aged; Alendronate; Calcium Channel Blockers; Canada; Estrogen Replacement Therapy; Etidronic Acid; F

2003
Bisphosphonates: new indications and methods of administration.
    Current opinion in rheumatology, 2003, Volume: 15, Issue:4

    Topics: Alendronate; Animals; Diphosphonates; Etidronic Acid; Fractures, Spontaneous; Humans; Imidazoles; Os

2003
An approach to postmenopausal osteoporosis treatment: a case study review.
    Journal of the American Academy of Nurse Practitioners, 2003, Volume: 15, Issue:12

    Topics: Aged; Alendronate; Bone Density; Calcitonin; Calcium, Dietary; Diphosphonates; Estrogen Replacement

2003
The use of bisphosphonates in the treatment of osteoporosis.
    Current opinion in rheumatology, 2005, Volume: 17, Issue:4

    Topics: Alendronate; Bone Density; Etidronic Acid; Female; Fractures, Spontaneous; Humans; Male; Osteogenesi

2005
Use of highly potent bisphosphonates in the treatment of osteoporosis.
    Current osteoporosis reports, 2003, Volume: 1, Issue:3

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Alendronate; Bone Density; Bone Remodeling; Diphosp

2003
Oral antiresorptive therapy.
    Current osteoporosis reports, 2004, Volume: 2, Issue:4

    Topics: Administration, Oral; Aged; Alendronate; Diphosphonates; Drug Therapy, Combination; Etidronic Acid;

2004
Fracture prevention in postmenopausal women.
    Clinical evidence, 2006, Issue:15

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Calcitonin; Calcium; Clodronic Acid; Diphosphon

2006
How long should patients take medications for postmenopausal osteoporosis?
    Joint bone spine, 2007, Volume: 74, Issue:1

    Topics: Aged; Aged, 80 and over; Alendronate; Biomarkers; Bone Density; Bone Density Conservation Agents; Dr

2007
Is cortical bone hip? What determines cortical bone properties?
    Bone, 2007, Volume: 41, Issue:1 Suppl 1

    Topics: Alendronate; Bone and Bones; Bone Density; Bone Remodeling; Etidronic Acid; Fractures, Spontaneous;

2007
[Glucocorticoid-induced osteoporosis].
    Polskie Archiwum Medycyny Wewnetrznej, 2007, Volume: 117, Issue:8

    Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Calcium; Diphosphonates; Female; Fractu

2007
Alendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women.
    The Cochrane database of systematic reviews, 2008, Jan-23, Issue:1

    Topics: Alendronate; Bone Density Conservation Agents; Female; Fractures, Bone; Fractures, Spontaneous; Hip

2008
[Alendronate also for women without established osteoporosis?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2000, Apr-30, Volume: 120, Issue:11

    Topics: Aged; Alendronate; Bone Density; Diphosphonates; Double-Blind Method; Evidence-Based Medicine; Femal

2000
Osteoporotic fractures at presentation of Cushing's disease: two case reports and a literature review.
    Joint bone spine, 2000, Volume: 67, Issue:4

    Topics: Absorptiometry, Photon; Adult; Alendronate; Bone and Bones; Cushing Syndrome; Fractures, Spontaneous

2000
Background for studies on the treatment of male osteoporosis: state of the art.
    Annals of the rheumatic diseases, 2000, Volume: 59, Issue:10

    Topics: Age Factors; Aged; Aged, 80 and over; Alendronate; Body Height; Body Weight; Bone Density; Fractures

2000
Improvement in spine bone density and reduction in risk of vertebral fractures during treatment with antiresorptive drugs.
    The American journal of medicine, 2002, Volume: 112, Issue:4

    Topics: Alendronate; Bone Density; Bone Resorption; Female; Fractures, Spontaneous; Humans; Logistic Models;

2002

Trials

7 trials available for alendronate and Fracture, Pathologic

ArticleYear
Value of routine monitoring of bone mineral density after starting bisphosphonate treatment: secondary analysis of trial data.
    BMJ (Clinical research ed.), 2009, Jun-23, Volume: 338

    Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Female; Fractures, Spontaneous; Hip Joi

2009
Comparison of plain vertebral X-ray and dual-energy X-ray absorptiometry for the identification of older women for fracture prevention in primary care.
    Internal medicine journal, 2013, Volume: 43, Issue:1

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Alendronate; Australia; Bone Density; Bone Density

2013
[A head-to-head comparative study for evaluation of effectiveness among drugs for osteoporosis].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2006, Volume: 43, Issue:1

    Topics: Aged; Alendronate; Bone and Bones; Bone Density; Bone Density Conservation Agents; Drug Evaluation;

2006
Alendronate and vitamin D2 for prevention of hip fracture in Parkinson's disease: a randomized controlled trial.
    Movement disorders : official journal of the Movement Disorder Society, 2006, Volume: 21, Issue:7

    Topics: Aged; Aged, 80 and over; Alendronate; Amino Acids; Bone Density; Bone Resorption; Calcium; Drug Ther

2006
[Should bisphosphonate treatment be used for super-old patients with osteoporosis?].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2006, Volume: 43, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Alendronate; Bone Density; Bone Density Conservation Agents; F

2006
An open-label extension study of alendronate treatment in elderly women with osteoporosis.
    Calcified tissue international, 1999, Volume: 64, Issue:6

    Topics: Absorptiometry, Photon; Administration, Oral; Aged; Aged, 80 and over; Alendronate; Bone Density; Do

1999
Larger increases in bone mineral density during alendronate therapy are associated with a lower risk of new vertebral fractures in women with postmenopausal osteoporosis. Fracture Intervention Trial Research Group.
    Arthritis and rheumatism, 1999, Volume: 42, Issue:6

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density; Female; Femur Neck; Fractures, Spontaneous; Huma

1999

Other Studies

71 other studies available for alendronate and Fracture, Pathologic

ArticleYear
A Case Report of Oral Bisphosphonate Treatment for Osteoporosis Leading to Atypical Femoral Fracture and Pathologic Mandibular Fracture.
    The American journal of case reports, 2023, Oct-23, Volume: 24

    Topics: Alendronate; Bone Density Conservation Agents; Diphosphonates; Female; Femoral Fractures; Fractures,

2023
[Subtrochanteric pathological fracture on bisphosphonates].
    Revue medicale de Liege, 2018, Volume: 73, Issue:2

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Diphosphonates; Female; Fractures, Spontaneous;

2018
Femoral fracture and temporomandibular joint destruction following the use of bisphosphonates.
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2015, Jan-27, Volume: 135, Issue:2

    Topics: Aged; Alendronate; Bisphosphonate-Associated Osteonecrosis of the Jaw; Diphosphonates; Female; Fract

2015
Management after first-line antiresorptive treatment for postmenopausal osteoporosis.
    Joint bone spine, 2016, Volume: 83, Issue:4

    Topics: Absorptiometry, Photon; Aged; Alendronate; Bone Density Conservation Agents; Denosumab; Dose-Respons

2016
Osteonecrosis of the jaw (ONJ) and atypical femoral fracture (AFF) in an osteoporotic patient chronically treated with bisphosphonates.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2017, Volume: 28, Issue:3

    Topics: Aged, 80 and over; Alendronate; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Con

2017
Maximizing effectiveness of bisphosphonate therapy for osteoporosis.
    Southern medical journal, 2008, Volume: 101, Issue:8

    Topics: Administration, Oral; Alendronate; Bone Density Conservation Agents; Diphosphonates; Etidronic Acid;

2008
A case report: pregnancy-induced severe osteoporosis with eight vertebral fractures.
    Rheumatology international, 2008, Volume: 29, Issue:2

    Topics: Adult; Alendronate; Back Pain; Bone Density; Bone Density Conservation Agents; Female; Fractures, Sp

2008
Comparison of radiographic fracture healing in the distal radius for patients on and off bisphosphonate therapy.
    The Journal of hand surgery, 2009, Volume: 34, Issue:4

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Bone Diseases, Metabolic; Bo

2009
Pathological fractures in patients caused by bisphosphonate-related osteonecrosis of the jaws: report of 3 cases.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009, Volume: 67, Issue:6

    Topics: Administration, Oral; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Diphosphonat

2009
Do not use bisphosphonate therapy indefinitely for fracture prevention.
    Prescrire international, 2008, Volume: 17, Issue:97

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density; Diphosphonates; Female; Fractures, Bone; Fractur

2008
Spontaneous femoral shaft fracture after long-term alendronate.
    Age and ageing, 2009, Volume: 38, Issue:5

    Topics: Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Bony Callus; Female; Femoral Fract

2009
Low-energy femoral fractures associated with the long-term use of bisphosphonates: a case series from a Swiss university hospital.
    Drug safety, 2009, Volume: 32, Issue:9

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Bone Nails; Diphosphonates;

2009
Conservative treatment of a pathologic fracture in a patient with Gorham-Stout disease.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2010, Volume: 109, Issue:2

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Female; Fracture Fixation; Fractures, Spontaneo

2010
Pathological fracture due to vertebral osteonecrosis associated with pancreatitis.
    Archives of orthopaedic and trauma surgery, 2011, Volume: 131, Issue:1

    Topics: Alendronate; Bone and Bones; Bone Density Conservation Agents; Disease Progression; Fat Necrosis; Fr

2011
Unusual case of a conservatively treated pathological fracture after sequestrectomy in a patient with long-term oral bisphosphonate use.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2011, Volume: 39, Issue:1

    Topics: Administration, Oral; Aged; Alendronate; Anti-Bacterial Agents; Bone Density Conservation Agents; Di

2011
Treatment outcomes in patients with bisphosphonate-related osteonecrosis of the jaws: a prospective study.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2010, Volume: 110, Issue:1

    Topics: Aged; Alcohol Drinking; Alendronate; Anti-Bacterial Agents; Bone Density Conservation Agents; Chroni

2010
Pathological mandibular fracture after simple molar extraction in a patient with osteogenesis imperfecta treated with alendronate.
    Medicina oral, patologia oral y cirugia bucal, 2010, Nov-01, Volume: 15, Issue:6

    Topics: Adult; Alendronate; Diphosphonates; Fractures, Spontaneous; Humans; Male; Mandibular Fractures; Mola

2010
Atraumatic bilateral femur fracture in long-term bisphosphonate use.
    Orthopedics, 2010, Volume: 33, Issue:7

    Topics: Alendronate; Bone Density Conservation Agents; Female; Femoral Fractures; Fractures, Spontaneous; Hu

2010
Alendronate-associated femoral insufficiency fractures and femoral stress reactions.
    Journal of orthopaedic surgery (Hong Kong), 2011, Volume: 19, Issue:1

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Bone Nails; Female; Femoral

2011
The effect of long-term alendronate treatment on cortical thickness of the proximal femur.
    Clinical orthopaedics and related research, 2012, Volume: 470, Issue:1

    Topics: Aged; Alendronate; Bone Density; Bone Density Conservation Agents; Case-Control Studies; Densitometr

2012
Bilateral pathologic hip fractures associated with antiretroviral therapy: a case report.
    The Journal of bone and joint surgery. American volume, 2011, Jul-20, Volume: 93, Issue:14

    Topics: Accidental Falls; Adenine; Alendronate; Anti-HIV Agents; Bone Density Conservation Agents; Comorbidi

2011
[Treatment with bisphosphonates as a possible cause of bilateral spontaneous atypical femoral fracture].
    Ugeskrift for laeger, 2012, Jan-09, Volume: 174, Issue:1-2

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Female; Fractures, Spontaneous; Hip Fractures;

2012
[Estimate of the 10-year risk of osteoporotic fractures in the Spanish population].
    Medicina clinica, 2013, Feb-02, Volume: 140, Issue:3

    Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Alendronate; Algorithms; Bone Density Conservation

2013
Hemimandibulectomy and vascularized fibula flap in bisphosphonate-induced mandibular osteonecrosis with polycythaemia rubra vera.
    International journal of oral and maxillofacial surgery, 2013, Volume: 42, Issue:1

    Topics: Aged, 80 and over; Alendronate; Aspirin; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone De

2013
Primary hyperparathyroidism with classic and severe skeletal involvement.
    BMJ case reports, 2010, Aug-26, Volume: 2010

    Topics: Adenoma; Alendronate; Calcitriol; Calcium Carbonate; Female; Follow-Up Studies; Fractures, Spontaneo

2010
Alendronate treatment for infants with osteogenesis imperfecta: demonstration of efficacy in a mouse model.
    Pediatric research, 2002, Volume: 52, Issue:5

    Topics: Alendronate; Animals; Biomechanical Phenomena; Bone and Bones; Bone Density; Collagen Type I; Diseas

2002
Intravenous pamidronate compared with oral alendronate for the treatment of postmenopausal osteoporosis.
    The Netherlands journal of medicine, 2002, Volume: 60, Issue:8

    Topics: Administration, Oral; Aged; Alendronate; Bone Density; Diphosphonates; Female; Fractures, Spontaneou

2002
Insufficiency fracture of the femoral neck during osteoporosis treatment: a case report.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2002, Volume: 7, Issue:6

    Topics: Administration, Oral; Aged; Alendronate; Bone Density; Bone Resorption; Dose-Response Relationship,

2002
[Fragility fracture and its control].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2003, Volume: 40, Issue:3

    Topics: Accidental Falls; Aged; Alendronate; Female; Fractures, Spontaneous; Hip Fractures; Humans; Male; Os

2003
[Alendronate once a week].
    Ugeskrift for laeger, 2003, Jun-30, Volume: 165, Issue:27

    Topics: Alendronate; Bone Density; Female; Fractures, Spontaneous; Gastrointestinal Diseases; Humans; Male;

2003
[Osteoporosis. Don't forget the men!].
    MMW Fortschritte der Medizin, 2003, Sep-11, Volume: 145, Issue:37

    Topics: Aged; Alendronate; Bone Density; Clinical Trials as Topic; Fractures, Spontaneous; Humans; Hydroxych

2003
[Cost-effectiveness of alendronate treatment of osteoporosis in Denmark. An economic evaluation based on the Fracture Intervention Trial].
    Ugeskrift for laeger, 2003, Oct-20, Volume: 165, Issue:43

    Topics: Aged; Alendronate; Cost of Illness; Cost-Benefit Analysis; Denmark; Drug Costs; Female; Fractures, S

2003
[Effects of different treatments for osteoporosis on prevention of fractures: toward and individualized and economic approach].
    Praxis, 2004, Mar-10, Volume: 93, Issue:11

    Topics: Aged; Aged, 80 and over; Alendronate; Calcitonin; Calcium; Cost-Benefit Analysis; Diphosphonates; Fe

2004
[Bisphosphonates in the prevention of vertebral and non-vertebral fractures in postmenopausal women with osteoporosis].
    Reumatizam, 2003, Volume: 50, Issue:2

    Topics: Alendronate; Diphosphonates; Etidronic Acid; Female; Fractures, Spontaneous; Humans; Middle Aged; Os

2003
Putting evidence-based medicine into clinical practice: comparing anti-resorptive agents for the treatment of osteoporosis.
    Current medical research and opinion, 2004, Volume: 20, Issue:4

    Topics: Alendronate; Bone Resorption; Evidence-Based Medicine; Female; Fractures, Spontaneous; Humans; Meta-

2004
Osteoporosis screening: time to take responsibility.
    Archives of internal medicine, 2004, May-24, Volume: 164, Issue:10

    Topics: Absorptiometry, Photon; Aged; Alendronate; Bone Density; Calcium Compounds; Female; Follow-Up Studie

2004
Bone mineral density thresholds for pharmacological intervention to prevent fractures.
    Archives of internal medicine, 2004, May-24, Volume: 164, Issue:10

    Topics: Age Distribution; Aged; Aged, 80 and over; Alendronate; Bone Density; Calcium Compounds; Cohort Stud

2004
[Data comparison of osteoporosis patients demonstrates nasal administration is not optimal].
    MMW Fortschritte der Medizin, 2004, Feb-12, Volume: 146, Issue:7

    Topics: Administration, Intranasal; Administration, Oral; Aerosols; Aged; Alendronate; Calcitonin; Etidronic

2004
[Risk of osteoporosis in postmenopausal women. When is bone density measurement indicated?].
    MMW Fortschritte der Medizin, 2004, May-20, Volume: 146, Issue:21

    Topics: Absorptiometry, Photon; Aged; Alendronate; Bone Density; Etidronic Acid; Evidence-Based Medicine; Fr

2004
[Are there differences in bisphosphonates? (interview by Dr. Beate Schumacher)].
    MMW Fortschritte der Medizin, 2004, Aug-05, Volume: 146, Issue:31-32

    Topics: Alendronate; Diphosphonates; Dose-Response Relationship, Drug; Etidronic Acid; Fractures, Spontaneou

2004
An ongoing six-year innovative osteoporosis disease management program: challenges and success in an IPA physician group environment.
    Disease management : DM, 2004,Fall, Volume: 7, Issue:3

    Topics: Absorptiometry, Photon; Age Distribution; Aged; Alendronate; California; Disease Management; Family

2004
[Update 2004. Osteoporosis--management--current status].
    Krankenpflege Journal, 2004, Volume: 42, Issue:7-10

    Topics: Aged; Aged, 80 and over; Alendronate; Calcium, Dietary; Cross-Sectional Studies; Etidronic Acid; Fem

2004
[Routine osteoporosis therapy].
    Krankenpflege Journal, 2004, Volume: 42, Issue:7-10

    Topics: Administration, Intranasal; Aged; Alendronate; Calcitonin; Clinical Trials as Topic; Diphosphonates;

2004
[Recent progress in osteoporosis research].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2005, Volume: 42, Issue:1

    Topics: Aged; Alendronate; Bone Density; Evidence-Based Medicine; Female; Fractures, Spontaneous; Genetic Pr

2005
Teriparatide: new preparation. Osteoporosis: less well evaluated than alendronic acid.
    Prescrire international, 2005, Volume: 14, Issue:75

    Topics: Alendronate; Animals; Bone Density; Clinical Trials as Topic; Drug Combinations; Female; Fractures,

2005
[Examination and treatment of orthopedic-surgery patients with osteoporosis-related fragility fractures].
    Ugeskrift for laeger, 2005, Nov-21, Volume: 167, Issue:47

    Topics: Adult; Aged; Alendronate; Bone Density; Bone Density Conservation Agents; Calcium; Etidronic Acid; F

2005
[Treating with what? Therapy for how long?].
    MMW Fortschritte der Medizin, 2005, Dec-15, Volume: 147, Issue:51-52

    Topics: Adult; Aged; Alendronate; Bone Density; Bone Density Conservation Agents; Clinical Trials as Topic;

2005
[Reliably combined to combat osteoporosis].
    MMW Fortschritte der Medizin, 2005, Dec-15, Volume: 147, Issue:51-52

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Clinical Trials as Topic; Drug Administration S

2005
[Pregnancy-associated osteoporosis. A new case].
    La Revue de medecine interne, 2006, Volume: 27, Issue:7

    Topics: Adult; Alendronate; Bone Density; Bone Density Conservation Agents; Female; Follow-Up Studies; Fract

2006
Osteoporotic fractures and vitamin D deficiency.
    Australian family physician, 2006, Volume: 35, Issue:7

    Topics: Absorptiometry, Photon; Aged; Alendronate; Bone Density Conservation Agents; Female; Femoral Fractur

2006
[Drug therapy for prevention of falls and fractures].
    Medizinische Klinik (Munich, Germany : 1983), 2006, Volume: 101 Suppl 1

    Topics: Accidental Falls; Alendronate; Bone Density Conservation Agents; Drug Therapy, Combination; Evidence

2006
[Bisphosphonate-related bilateral mandibular osteochemonecrosis with pathological fracture of the horizontal ramus].
    Revue de stomatologie et de chirurgie maxillo-faciale, 2006, Volume: 107, Issue:5

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Fractures, Spontaneous; Humans; Male; Mandibula

2006
Cost-effectiveness of alendronate in the treatment of postmenopausal women in 9 European countries--an economic evaluation based on the fracture intervention trial.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2007, Volume: 18, Issue:8

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Computer Simulation; Cost-Be

2007
Gaps in treatment among users of osteoporosis medications: the dynamics of noncompliance.
    The American journal of medicine, 2007, Volume: 120, Issue:3

    Topics: Aged; Aged, 80 and over; Alendronate; Attitude to Health; Bone Density; Bone Density Conservation Ag

2007
A claims database analysis of persistence with alendronate therapy and fracture risk in post-menopausal women with osteoporosis.
    Current medical research and opinion, 2007, Volume: 23, Issue:3

    Topics: Age Distribution; Aged; Alendronate; Bone Density; Bone Density Conservation Agents; Cohort Studies;

2007
[Correlation between studies and general practice].
    MMW Fortschritte der Medizin, 2006, Nov-16, Volume: 148, Issue:46

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Calcitonin; Etidronic Acid; Family Practice; Fe

2006
[Osteoporosis compounds in general practice. That is REAL: in routine practice the better choice].
    MMW Fortschritte der Medizin, 2007, Mar-29, Volume: 149, Issue:13

    Topics: Alendronate; Bone Density Conservation Agents; Cohort Studies; Etidronic Acid; Female; Fractures, Sp

2007
[Long term effects of raloxifen on the bones].
    Ugeskrift for laeger, 2008, Jan-21, Volume: 170, Issue:4

    Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Drug Therapy, Combination; Female; Frac

2008
[Alendronate (Fosamax 10 mg). The first amino-biphosphate for the treatment of women with postmenopausal osteoporosis].
    Geburtshilfe und Frauenheilkunde, 1996, Volume: 56, Issue:10 Suppl

    Topics: Aged; Alendronate; Diphosphonates; Dose-Response Relationship, Drug; Female; Femoral Neck Fractures;

1996
[Does alendronate reduce the risk of fractures in postmenopausal women with osteoporosis?].
    Praxis, 1997, Apr-09, Volume: 86, Issue:15

    Topics: Aged; Alendronate; Female; Fractures, Spontaneous; Humans; Middle Aged; Osteoporosis, Postmenopausal

1997
Prevention of hip fractures in older women: a population-based perspective.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1998, Volume: 8 Suppl 1

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density; Calcium; Estrogen Replacement Therapy; Exercise;

1998
[New knowledge on alendronate (Fosamax) and fractures].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1999, Feb-20, Volume: 119, Issue:5

    Topics: Alendronate; Diphosphonates; Female; Fractures, Spontaneous; Humans; Osteoporosis, Postmenopausal

1999
[Fast protection against osteoporotic fractures by using alendronat].
    Der Orthopade, 1999, Volume: 28, Issue:4 Suppl

    Topics: Alendronate; Diphosphonates; Female; Fractures, Spontaneous; Humans; Osteoporosis, Postmenopausal

1999
[Research philosophy and practical research--new knowledge about alendronate and fractures].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1999, Apr-30, Volume: 119, Issue:11

    Topics: Alendronate; Female; Fractures, Spontaneous; Humans; Osteoporosis, Postmenopausal; Research

1999
[A new type of iliac fracture caused by bone insufficiency].
    Presse medicale (Paris, France : 1983), 1999, Jun-19, Volume: 28, Issue:22

    Topics: Alendronate; Bone Density; Calcium; Densitometry; Diphosphonates; Female; Fractures, Spontaneous; Hu

1999
[Most recent study results show: the bisphosphonate alendronate works more rapidly than previously assumed].
    MMW Fortschritte der Medizin, 2000, Jul-06, Volume: 142, Issue:26-27

    Topics: Alendronate; Evidence-Based Medicine; Fractures, Spontaneous; Hip Fractures; Humans; Osteoporosis; T

2000
Bisphosphonate therapy in fibrous dysplasia.
    Clinical orthopaedics and related research, 2001, Issue:382

    Topics: Administration, Oral; Adult; Aged; Alendronate; Biomarkers; Bone and Bones; Collagen; Collagen Type

2001
[Osteoporosis and multiple pregnancy--a case report with positive outcome].
    Medizinische Klinik (Munich, Germany : 1983), 2001, Jul-15, Volume: 96, Issue:7

    Topics: Adult; Alendronate; Bone Density; Calcium Channel Agonists; Calcium, Dietary; Cholecalciferol; Contr

2001
Alendronate for the treatment of osteoporosis in men.
    Calcified tissue international, 2001, Volume: 69, Issue:4

    Topics: Alendronate; Bone Density; Climacteric; Female; Fractures, Spontaneous; Humans; Lumbar Vertebrae; Ma

2001
[Economic aspects of osteoporosis therapy. What does a prevented fracture cost?].
    MMW Fortschritte der Medizin, 2001, Nov-22, Volume: 143, Issue:47

    Topics: Aged; Alendronate; Cost-Benefit Analysis; Etidronic Acid; Female; Fractures, Spontaneous; Germany; H

2001
[Convenient and well-tolerated therapy of osteoporosis. Preventing fractures only once a week].
    MMW Fortschritte der Medizin, 2002, Apr-25, Volume: 144, Issue:17

    Topics: Aged; Alendronate; Drug Administration Schedule; Female; Fractures, Spontaneous; Humans; Middle Aged

2002