alendronate has been researched along with Experimental Neoplasms in 6 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1 mg/kg twice weekly or weekly) and dosing along with taxol (10-50 mg/kg/day, twice weekly, or weekly) blocked the growth of PC-3 ML tumors in the bone marrow and soft tissues in a statistically significant manner and improved survival rates significantly (p < 0." | 5.29 | Effects of alendronate and taxol on PC-3 ML cell bone metastases in SCID mice. ( Stearns, ME; Wang, M, 1996) |
| " Only one study so far has proven the therapeutic efficacy of L-ALD, in combination with γδ T cell immunotherapy, after intraperitoneal administration of γδ T cell resulting in delayed growth of ovarian cancer in mice." | 1.43 | In vitro potency, in vitro and in vivo efficacy of liposomal alendronate in combination with γδ T cell immunotherapy in mice. ( Al-Jamal, KT; Al-Jamal, WT; Hodgins, NO; Liu, M; Maher, J; Parente-Pereira, AC; Wang, JT, 2016) |
| "1 mg/kg twice weekly or weekly) and dosing along with taxol (10-50 mg/kg/day, twice weekly, or weekly) blocked the growth of PC-3 ML tumors in the bone marrow and soft tissues in a statistically significant manner and improved survival rates significantly (p < 0." | 1.29 | Effects of alendronate and taxol on PC-3 ML cell bone metastases in SCID mice. ( Stearns, ME; Wang, M, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Madka, V | 1 |
| Kumar, G | 1 |
| Pathuri, G | 1 |
| Zhang, Y | 2 |
| Lightfoot, S | 1 |
| Asch, AS | 1 |
| Mohammed, A | 1 |
| Steele, VE | 1 |
| Rao, CV | 1 |
| Swami, A | 1 |
| Reagan, MR | 1 |
| Basto, P | 1 |
| Mishima, Y | 1 |
| Kamaly, N | 1 |
| Glavey, S | 1 |
| Zhang, S | 1 |
| Moschetta, M | 1 |
| Seevaratnam, D | 1 |
| Liu, J | 1 |
| Memarzadeh, M | 1 |
| Wu, J | 1 |
| Manier, S | 1 |
| Shi, J | 1 |
| Bertrand, N | 1 |
| Lu, ZN | 1 |
| Nagano, K | 1 |
| Baron, R | 1 |
| Sacco, A | 1 |
| Roccaro, AM | 1 |
| Farokhzad, OC | 1 |
| Ghobrial, IM | 1 |
| Zhan, X | 1 |
| Jia, L | 1 |
| Niu, Y | 1 |
| Qi, H | 1 |
| Chen, X | 1 |
| Zhang, Q | 1 |
| Zhang, J | 1 |
| Wang, Y | 1 |
| Dong, L | 1 |
| Wang, C | 1 |
| Shmeeda, H | 1 |
| Amitay, Y | 1 |
| Gorin, J | 1 |
| Tzemach, D | 1 |
| Mak, L | 1 |
| Stern, ST | 1 |
| Barenholz, Y | 1 |
| Gabizon, A | 1 |
| Hodgins, NO | 1 |
| Al-Jamal, WT | 1 |
| Wang, JT | 1 |
| Parente-Pereira, AC | 1 |
| Liu, M | 1 |
| Maher, J | 1 |
| Al-Jamal, KT | 1 |
| Stearns, ME | 1 |
| Wang, M | 1 |
6 other studies available for alendronate and Experimental Neoplasms
| Article | Year |
|---|---|
Bisphosphonates Zometa and Fosamax Synergize with Metformin to Prevent AOM-Induced Colon Cancer in F344 Rat Model.
Topics: Administration, Oral; Alendronate; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cell P | 2020 |
Engineered nanomedicine for myeloma and bone microenvironment targeting.
Topics: Alendronate; Animals; Antineoplastic Agents; Bone Neoplasms; Boronic Acids; Bortezomib; Cell Line, T | 2014 |
Targeted depletion of tumour-associated macrophages by an alendronate-glucomannan conjugate for cancer immunotherapy.
Topics: Alendronate; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; F | 2014 |
Coencapsulation of alendronate and doxorubicin in pegylated liposomes: a novel formulation for chemoimmunotherapy of cancer.
Topics: Alendronate; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Doxorubicin; Female; H | 2016 |
In vitro potency, in vitro and in vivo efficacy of liposomal alendronate in combination with γδ T cell immunotherapy in mice.
Topics: Alendronate; Animals; Cell Line, Tumor; Cell Survival; Coculture Techniques; Cytotoxicity, Immunolog | 2016 |
Effects of alendronate and taxol on PC-3 ML cell bone metastases in SCID mice.
Topics: Alendronate; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protoc | 1996 |