Page last updated: 2024-10-22

alendronate and Ectopic Ossification

alendronate has been researched along with Ectopic Ossification in 5 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Research Excerpts

ExcerptRelevanceReference
"Alendronate treatment of OPG-/- mice resulted in enhancement of the volume of heterotopic new bone."1.33Enhancement of crude bone morphogenetic protein-induced new bone formation and normalization of endochondral ossification by bisphosphonate treatment in osteoprotegerin-deficient mice. ( Goto, S; Kameyama, Y; Kawai, T; Kimura, M; Maeda, H; Miyazawa, K; Tabuchi, M, 2005)
"When alendronate was injected at 3, 4, and 5 weeks, the bone mass increased by 70% and by 166% after 6 and 10 weeks, respectively, in comparison to the untreated control."1.32The influence of alendronate on bone formation and resorption in a rat ectopic bone development model. ( Bahar, H; Binderman, I; Kollerman, R; Yaffe, A, 2003)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Song, B1
Sambasivan, A1
Ploumis, A1
Donovan, JM1
Olurinde, MO1
Clark, DM1
Wu, JC1
Sohn, DJ1
O'Connor, KC1
Kawao, N1
Yano, M1
Tamura, Y1
Okumoto, K1
Okada, K1
Kaji, H1
Yaffe, A1
Kollerman, R1
Bahar, H1
Binderman, I1
Tabuchi, M1
Miyazawa, K1
Kimura, M1
Maeda, H1
Kawai, T1
Kameyama, Y1
Goto, S1

Trials

1 trial available for alendronate and Ectopic Ossification

ArticleYear
Association between alendronate, serum alkaline phosphatase level, and heterotopic ossification in individuals with spinal cord injury.
    The journal of spinal cord medicine, 2015, Volume: 38, Issue:2

    Topics: Administration, Oral; Adult; Alendronate; Alkaline Phosphatase; Female; Humans; Male; Middle Aged; O

2015

Other Studies

4 other studies available for alendronate and Ectopic Ossification

ArticleYear
Utilization of Diagnostic Ultrasound in Early Detection of Heterotopic Ossification Causing Ulnar Nerve Compression.
    American journal of physical medicine & rehabilitation, 2021, 02-01, Volume: 100, Issue:2

    Topics: Adult; Alendronate; Bone Density Conservation Agents; Female; Humans; Ossification, Heterotopic; Uln

2021
Role of osteoclasts in heterotopic ossification enhanced by fibrodysplasia ossificans progressiva-related activin-like kinase 2 mutation in mice.
    Journal of bone and mineral metabolism, 2016, Volume: 34, Issue:5

    Topics: Activin Receptors, Type I; Alendronate; Alkaline Phosphatase; Animals; Benzamides; Calcium; Cell Lin

2016
The influence of alendronate on bone formation and resorption in a rat ectopic bone development model.
    Journal of periodontology, 2003, Volume: 74, Issue:1

    Topics: Alendronate; Analysis of Variance; Animals; Bone Density; Bone Diseases, Metabolic; Bone Marrow; Bon

2003
Enhancement of crude bone morphogenetic protein-induced new bone formation and normalization of endochondral ossification by bisphosphonate treatment in osteoprotegerin-deficient mice.
    Calcified tissue international, 2005, Volume: 77, Issue:4

    Topics: Alendronate; Alkaline Phosphatase; Animals; Bone Morphogenetic Proteins; Bone Resorption; Cattle; Ch

2005