alendronate has been researched along with Depressive Disorder, Major in 3 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In premenopausal women with MDD, reduced daily adiponectin production may increase the risk of diabetes mellitus, and elevated leptin may contribute to osteoporosis." | 7.76 | Low 24-hour adiponectin and high nocturnal leptin concentrations in a case-control study of community-dwelling premenopausal women with major depressive disorder: the Premenopausal, Osteopenia/Osteoporosis, Women, Alendronate, Depression (POWER) study. ( Ahima, RS; Blackman, MR; Cizza, G; Duan, Z; Eskandari, F; Nguyen, VT; Reynolds, JC; Wright, EC, 2010) |
| "In premenopausal women with MDD, reduced daily adiponectin production may increase the risk of diabetes mellitus, and elevated leptin may contribute to osteoporosis." | 3.76 | Low 24-hour adiponectin and high nocturnal leptin concentrations in a case-control study of community-dwelling premenopausal women with major depressive disorder: the Premenopausal, Osteopenia/Osteoporosis, Women, Alendronate, Depression (POWER) study. ( Ahima, RS; Blackman, MR; Cizza, G; Duan, Z; Eskandari, F; Nguyen, VT; Reynolds, JC; Wright, EC, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cizza, G | 3 |
| Nguyen, VT | 1 |
| Eskandari, F | 2 |
| Duan, Z | 1 |
| Wright, EC | 1 |
| Reynolds, JC | 2 |
| Ahima, RS | 1 |
| Blackman, MR | 2 |
| Ronsaville, DS | 1 |
| Kleitz, H | 1 |
| Mistry, S | 1 |
| Torvik, S | 2 |
| Sonbolian, N | 2 |
| Gold, PW | 1 |
| Martinez, PE | 1 |
| Hartman, JM | 1 |
| Berger, A | 1 |
| Baker, K | 1 |
| Bolle, J | 1 |
| Handel, D | 1 |
| Mannes, A | 1 |
| Pereira, D | 1 |
| St Germain, D | 1 |
| Ronsaville, D | 1 |
| Calis, KA | 1 |
| Phillips, TM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The P.O.W.E.R. STUDY (Premenopause, Osteopenia/Osteoporosis, Women, Alendronate, Depression)[NCT00006180] | Phase 4 | 220 participants | Interventional | 2000-08-10 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for alendronate and Depressive Disorder, Major
| Article | Year |
|---|---|
Clinical subtypes of depression are associated with specific metabolic parameters and circadian endocrine profiles in women: the power study.
Topics: Adrenocorticotropic Hormone; Adult; Alendronate; Biomarkers; Body Composition; Bone Density; Circadi | 2012 |
Quality of life and pain in premenopausal women with major depressive disorder: the POWER Study.
Topics: Adult; Alendronate; Bone Density; Bone Density Conservation Agents; Calcitonin Gene-Related Peptide; | 2006 |
1 other study available for alendronate and Depressive Disorder, Major
| Article | Year |
|---|---|
Low 24-hour adiponectin and high nocturnal leptin concentrations in a case-control study of community-dwelling premenopausal women with major depressive disorder: the Premenopausal, Osteopenia/Osteoporosis, Women, Alendronate, Depression (POWER) study.
Topics: Adiponectin; Adrenocorticotropic Hormone; Adult; Alendronate; Body Mass Index; Case-Control Studies; | 2010 |