alendronate has been researched along with Degenerative Disc Disease in 3 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Osteoporosis adversely affects disc degeneration cascades, and prophylactic alendronate (ALN) helps delay intervertebral disc degeneration (IDD) in ovariectomized (OVX) rats." | 7.85 | Effects of alendronate on lumbar intervertebral disc degeneration with bone loss in ovariectomized rats. ( Dai, M; Li, S; Luo, Y; Shen, Y; Song, H; Wang, W; Yang, K; Zhang, L; Zhang, Y, 2017) |
| "A model of disc degeneration adjacent to a lumbar fusion in osteoporotic rats." | 5.42 | Alendronate Prevents Intervertebral Disc Degeneration Adjacent to a Lumbar Fusion in Ovariectomized Rats. ( Gou, Y; Song, HP; Tian, FM; Wang, P; Wang, WY; Zhang, H; Zhang, L; Zhou, Z, 2015) |
| "Alendronate (ALN) can increase bone mass and improve the microstructure of osteoporotic vertebrae, which might be helpful in preserving disc morphology and mechanical properties." | 5.39 | Alendronate retards the progression of lumbar intervertebral disc degeneration in ovariectomized rats. ( Hu, QF; Luo, Y; Song, HP; Su, YL; Wang, WY; Zhang, L; Zhang, YZ, 2013) |
| "Osteoporosis adversely affects disc degeneration cascades, and prophylactic alendronate (ALN) helps delay intervertebral disc degeneration (IDD) in ovariectomized (OVX) rats." | 3.85 | Effects of alendronate on lumbar intervertebral disc degeneration with bone loss in ovariectomized rats. ( Dai, M; Li, S; Luo, Y; Shen, Y; Song, H; Wang, W; Yang, K; Zhang, L; Zhang, Y, 2017) |
| "A model of disc degeneration adjacent to a lumbar fusion in osteoporotic rats." | 1.42 | Alendronate Prevents Intervertebral Disc Degeneration Adjacent to a Lumbar Fusion in Ovariectomized Rats. ( Gou, Y; Song, HP; Tian, FM; Wang, P; Wang, WY; Zhang, H; Zhang, L; Zhou, Z, 2015) |
| "Alendronate (ALN) can increase bone mass and improve the microstructure of osteoporotic vertebrae, which might be helpful in preserving disc morphology and mechanical properties." | 1.39 | Alendronate retards the progression of lumbar intervertebral disc degeneration in ovariectomized rats. ( Hu, QF; Luo, Y; Song, HP; Su, YL; Wang, WY; Zhang, L; Zhang, YZ, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luo, Y | 2 |
| Zhang, L | 3 |
| Wang, WY | 2 |
| Hu, QF | 1 |
| Song, HP | 2 |
| Su, YL | 1 |
| Zhang, YZ | 1 |
| Zhou, Z | 1 |
| Tian, FM | 1 |
| Wang, P | 1 |
| Gou, Y | 1 |
| Zhang, H | 1 |
| Song, H | 1 |
| Wang, W | 1 |
| Li, S | 1 |
| Yang, K | 1 |
| Dai, M | 1 |
| Shen, Y | 1 |
| Zhang, Y | 1 |
3 other studies available for alendronate and Degenerative Disc Disease
| Article | Year |
|---|---|
Alendronate retards the progression of lumbar intervertebral disc degeneration in ovariectomized rats.
Topics: Absorptiometry, Photon; Alendronate; Animals; Biomechanical Phenomena; Bone Density; Bone Density Co | 2013 |
Alendronate Prevents Intervertebral Disc Degeneration Adjacent to a Lumbar Fusion in Ovariectomized Rats.
Topics: Alendronate; Animals; Bone Density; Bone Density Conservation Agents; Female; Intervertebral Disc; I | 2015 |
Effects of alendronate on lumbar intervertebral disc degeneration with bone loss in ovariectomized rats.
Topics: Alendronate; Animals; Bone Density Conservation Agents; Cartilage; Collagen Type II; Female; Humans; | 2017 |