Page last updated: 2024-10-22

alendronate and Coronary Restenosis

alendronate has been researched along with Coronary Restenosis in 4 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Coronary Restenosis: Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.

Research Excerpts

ExcerptRelevanceReference
"The current treatment for coronary restenosis following balloon angioplasty involves the use of a mechanical or drug eluting stent (DES)."2.48Liposomal alendronate for the treatment of restenosis. ( Golomb, G; Gutman, D, 2012)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grad, E1
Zolotarevsky, K1
Danenberg, HD1
Nordling-David, MM1
Gutman, D2
Golomb, G2
Park, K1
Banai, S1
Finkelstein, A1
Almagor, Y1
Assali, A1
Hasin, Y1
Rosenschein, U1
Apruzzese, P1
Lansky, AJ1
Kume, T1
Edelman, ER1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intravenous Liposomal Alendronate Infusion in Subjects Undergoing Bare Metal Coronary Stent Implantation[NCT00739466]Phase 2226 participants (Actual)Interventional2008-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for alendronate and Coronary Restenosis

ArticleYear
Liposomal alendronate for the treatment of restenosis.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Jul-20, Volume: 161, Issue:2

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Coronary Restenosis; Humans; Liposomes; Macr

2012

Trials

1 trial available for alendronate and Coronary Restenosis

ArticleYear
Targeted anti-inflammatory systemic therapy for restenosis: the Biorest Liposomal Alendronate with Stenting sTudy (BLAST)-a double blind, randomized clinical trial.
    American heart journal, 2013, Volume: 165, Issue:2

    Topics: Administration, Intravenous; Alendronate; Coronary Angiography; Coronary Restenosis; Dose-Response R

2013

Other Studies

2 other studies available for alendronate and Coronary Restenosis

ArticleYear
The role of monocyte subpopulations in vascular injury following partial and transient depletion.
    Drug delivery and translational research, 2018, Volume: 8, Issue:4

    Topics: Alendronate; Animals; Carotid Artery Injuries; Clodronic Acid; Coronary Restenosis; Liposomes; Male;

2018
A new method for preventing restenosis: a single IV injection of drug-loaded nanoparticles.
    Journal of controlled release : official journal of the Controlled Release Society, 2009, Jan-19, Volume: 133, Issue:2

    Topics: Alendronate; Animals; Cell Line; Cell Survival; Clinical Trials, Phase II as Topic; Coronary Resteno

2009