alendronate has been researched along with Colitis in 3 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Another inhibitor of prenylation, namely alendronate, reduces colitis in rodents." | 7.83 | The Bisphosphonate Pamidronate is an Intestinal Antiinflammatory Agent in Rat and Mouse Experimental Colitis. ( González, R; López-Posadas, R; Martínez-Augustin, O; Mascaraque, C; Sánchez de Medina, F; Suárez, MD; Zarzuelo, A, 2016) |
| "Alendronate treatment (25 or 75 mg kg(-1) day(-1)) resulted in a decrease in the colonic damage score and loss of body weight (at 25 mg kg(-1) day(-1) only)." | 7.74 | The bisphosphonate alendronate improves the damage associated with trinitrobenzenesulfonic acid-induced colitis in rats. ( Ballester, I; Daddaoua, A; López-Posadas, R; Martínez-Augustin, O; Nieto, A; Sánchez de Medina, F; Suárez, MD; Zarzuelo, A, 2007) |
| " Another inhibitor of prenylation, namely alendronate, reduces colitis in rodents." | 3.83 | The Bisphosphonate Pamidronate is an Intestinal Antiinflammatory Agent in Rat and Mouse Experimental Colitis. ( González, R; López-Posadas, R; Martínez-Augustin, O; Mascaraque, C; Sánchez de Medina, F; Suárez, MD; Zarzuelo, A, 2016) |
| "Alendronate treatment (25 or 75 mg kg(-1) day(-1)) resulted in a decrease in the colonic damage score and loss of body weight (at 25 mg kg(-1) day(-1) only)." | 3.74 | The bisphosphonate alendronate improves the damage associated with trinitrobenzenesulfonic acid-induced colitis in rats. ( Ballester, I; Daddaoua, A; López-Posadas, R; Martínez-Augustin, O; Nieto, A; Sánchez de Medina, F; Suárez, MD; Zarzuelo, A, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| López-Posadas, R | 2 |
| Mascaraque, C | 1 |
| González, R | 1 |
| Suárez, MD | 2 |
| Zarzuelo, A | 2 |
| Martínez-Augustin, O | 2 |
| Sánchez de Medina, F | 2 |
| Parfitt, JR | 1 |
| Driman, DK | 1 |
| Ballester, I | 1 |
| Daddaoua, A | 1 |
| Nieto, A | 1 |
1 review available for alendronate and Colitis
| Article | Year |
|---|---|
Pathological effects of drugs on the gastrointestinal tract: a review.
Topics: Alendronate; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Colitis; Drug-Related Side Effects | 2007 |
2 other studies available for alendronate and Colitis
| Article | Year |
|---|---|
The Bisphosphonate Pamidronate is an Intestinal Antiinflammatory Agent in Rat and Mouse Experimental Colitis.
Topics: Alendronate; Animals; Anti-Inflammatory Agents; Colitis; Dextran Sulfate; Diphosphonates; Ibandronic | 2016 |
The bisphosphonate alendronate improves the damage associated with trinitrobenzenesulfonic acid-induced colitis in rats.
Topics: Administration, Oral; Alendronate; Animals; Anti-Inflammatory Agents; Body Weight; Bone Density Cons | 2007 |