Page last updated: 2024-10-22

alendronate and Cholera Infantum

alendronate has been researched along with Cholera Infantum in 41 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Research Excerpts

ExcerptRelevanceReference
"Alendronate 70 mg administered once weekly to women and men with osteoporosis has an upper GI and overall tolerability profile similar to that of placebo."9.11Upper gastrointestinal and overall tolerability of alendronate once weekly in patients with osteoporosis: results of a randomized, double-blind, placebo-controlled study. ( Eisman, JA; Gaines, KA; Lipschitz, S; Melton, ME; Rizzoli, R; Roman-Ivorra, J; Verbruggen, N, 2004)
" The study enrolled 450 postmenopausal women and men with osteoporosis (224 took alendronate, 226 took placebo) who were ambulatory and community dwelling at 48 outpatient study centers in the United States."9.10Tolerability of once-weekly alendronate in patients with osteoporosis: a randomized, double-blind, placebo-controlled study. ( de Papp, AE; Field-Munves, E; Greenspan, S; Palmisano, J; Petruschke, R; Smith, M; Tonino, R; Wang, L; Yates, J, 2002)
"The aim of our study was to evaluate the upper gastrointestinal (GI) tract side effect profile in 759 female patients that had taken alendronate (10 mg/day), for at least 6 months, for the treatment of osteoporosis, in relation to the safety of alendronate and the compliance of patients to its absorption rules."7.72Gastrointestinal side effect profile due to the use of alendronate in the treatment of osteoporosis. ( Akarirmak, U; Aki, S; Akyüz, G; Alper, S; Arpacioğlu, O; Atalay, F; Eryavuz, M; Eskiyurt, N; Kavuncu, V; Kokino, S; Kuru, O; Nas, K; Ozerbil, O; Savaş, G; Sendur, OF; Soy, D; Tüzün, F, 2003)
"Alendronate 70 mg administered once weekly to women and men with osteoporosis has an upper GI and overall tolerability profile similar to that of placebo."5.11Upper gastrointestinal and overall tolerability of alendronate once weekly in patients with osteoporosis: results of a randomized, double-blind, placebo-controlled study. ( Eisman, JA; Gaines, KA; Lipschitz, S; Melton, ME; Rizzoli, R; Roman-Ivorra, J; Verbruggen, N, 2004)
" A total of 450 (224 alendronate; 226 placebo) postmenopausal women and men with osteoporosis were randomized."5.11Upper gastrointestinal tolerability of once weekly alendronate 70 mg with concomitant non-steroidal anti-inflammatory drug use. ( Chen, E; Cryer, B; Geba, GP; Miller, P; Papp, AE; Petruschke, RA, 2005)
" The study enrolled 450 postmenopausal women and men with osteoporosis (224 took alendronate, 226 took placebo) who were ambulatory and community dwelling at 48 outpatient study centers in the United States."5.10Tolerability of once-weekly alendronate in patients with osteoporosis: a randomized, double-blind, placebo-controlled study. ( de Papp, AE; Field-Munves, E; Greenspan, S; Palmisano, J; Petruschke, R; Smith, M; Tonino, R; Wang, L; Yates, J, 2002)
"Alendronate is a second generation bisphosphonate which has been widely used in medical practice for two decades to treat osteoporosis and prevent fragility fractures both in elderly people and in younger patients."4.90Alendronate: new formulations of an old and effective drug to improve adherence avoiding upper gastrointestinal side effects. ( Auriemma, R; Migliore, A; Neglia, C; Piscitelli, P, 2014)
"Alendronate sodium is an aminobiphosphonate, an analog of inorganic pyrophosphate, indicated for the treatment of osteoporosis in post-menopausal women."3.72Pharmacovigilance study of alendronate in England. ( Biswas, PN; Shakir, SA; Wilton, LV, 2003)
"The aim of our study was to evaluate the upper gastrointestinal (GI) tract side effect profile in 759 female patients that had taken alendronate (10 mg/day), for at least 6 months, for the treatment of osteoporosis, in relation to the safety of alendronate and the compliance of patients to its absorption rules."3.72Gastrointestinal side effect profile due to the use of alendronate in the treatment of osteoporosis. ( Akarirmak, U; Aki, S; Akyüz, G; Alper, S; Arpacioğlu, O; Atalay, F; Eryavuz, M; Eskiyurt, N; Kavuncu, V; Kokino, S; Kuru, O; Nas, K; Ozerbil, O; Savaş, G; Sendur, OF; Soy, D; Tüzün, F, 2003)
"Osteoporosis is defined as a reduction of bone density or the presence of a fragility fracture."2.76Comparison of gastrointestinal symptoms at daily 10 mg versus weekly 70 mg Alendronate prescription in 195 osteoporotic cases. ( Amiri, AH; Tarrahi, MJ, 2011)
"The aim of this study was to provide confirmation that once-weekly dosing with 70 mg of alendronate (seven times the daily oral dose) and twice-weekly dosing with 35 mg is equivalent to the 10-mg once-daily regimen and to gain more extensive safety experience with this new dosing regimen."2.70Two-year results of once-weekly administration of alendronate 70 mg for the treatment of postmenopausal osteoporosis. ( Adami, S; Bone, G; Foldes, AJ; Greenspan, SL; Kaur, A; Levine, MA; Orloff, JJ; Peverly, CA; Rizzoli, R; Roux, C; Santora, AC; Schnitzer, TJ; Uebelhart, B; Watts, NB, 2002)
"Alendronate use was not associated with a significant increase in upper GI tract events among women at increased risk for these events (those aged > or =75 years with previous upper GI tract disease or using nonsteroidal anti-inflammatory drugs)."2.69Upper gastrointestinal tract safety profile of alendronate: the fracture intervention trial. ( Bauer, DC; Black, D; Ensrud, K; Freedholm, D; Hochberg, M; Musliner, T; Nevitt, M; Thompson, D, 2000)
" Less frequent dosing with any medication may enhance compliance, thereby maximizing the effectiveness of therapy."2.69Therapeutic equivalence of alendronate 70 mg once-weekly and alendronate 10 mg daily in the treatment of osteoporosis. Alendronate Once-Weekly Study Group. ( Adami, S; Bone, HG; Crepaldi, G; Emkey, R; Felsenberg, D; Foldes, AJ; Greenspan, SL; Kaur, A; Kiel, D; Levine, MA; McClung, M; Orloff, JJ; Pinchera, A; Recker, RR; Roux, C; Santora, AC; Schnitzer, T; Thompson, DE; Tonino, RP; Yates, J, 2000)
"Osteoporotic fractures are a public health problem and their incidence and subsequent economic and social costs are expected to rise in the next future."2.52The potential impact of new effervescent alendronate formulation on compliance and persistence in osteoporosis treatment. ( Carda, S; Cisari, C; Invernizzi, M, 2015)
"The data on gastrointestinal side effects (47 trials) indicated that alendronate, risedronate etidronate, and zolendronate have similar rates of the adverse effects; application of Bayesian network meta-analysis showed that equivalence was demonstrated according to margins around ±10%."2.52Gastrointestinal and renal side effects of bisphosphonates: differentiating between no proof of difference and proof of no difference. ( Fadda, V; Maratea, D; Messori, A; Trippoli, S, 2015)
"Pain is one of the most common symptoms in children and young people (CYP) with life-limiting conditions (LLCs) which include a wide range of diagnoses including cancer."2.52Pharmacological interventions for pain in children and adolescents with life-limiting conditions. ( Beecham, E; Bluebond-Langner, M; Candy, B; Howard, R; Jones, L; Laddie, J; McCulloch, R; Rees, H; Vickerstaff, V, 2015)
"etidronate) have been associated with acute renal failure."2.44Safety considerations with bisphosphonates for the treatment of osteoporosis. ( Civitelli, R; Emkey, R; Strampel, W, 2007)
"Oral daily bisphosphonates carry a potential for gastrointestinal (GI) adverse events, which has been partly addressed by introducing once-weekly regimens."2.43Oral ibandronate in the management of postmenopausal osteoporosis: review of upper gastrointestinal safety. ( Delmas, PD; Emkey, R; Epstein, S; Hiltbrunner, V; Schimmer, RC; Wilson, KM, 2006)
" The risk of an adverse upper GI event increases when these drugs are used concurrently with nonsteroidal anti-inflammatory drug (NSAID) therapy, but this incidence is no more than that observed with concurrent placebo and NSAID therapy."2.41Alendronate and risedronate: what you need to know about their upper gastrointestinal tract toxicity. ( Baker, DE, 2002)
" The manuscript then reviews therapies available for osteoporosis in the United States and makes recommendations about choosing therapies that minimize GI adverse effects in RA patients at high risk for such events."2.41Osteoporosis therapies for rheumatoid arthritis patients: minimizing gastrointestinal side effects. ( Schein, JR; Sewell, K, 2001)
"Alendronate is a potent bisphosphonate that is effective in preventing osteoporotic fractures."2.40The clinical tolerability profile of alendronate. ( Daifotis, A; Freedholm, D; Watts, N, 1999)
"Patients with symptoms of osteoporosis, prostate cancer, or breast cancer were surveyed to determine their knowledge of bisphosphonates."1.38Awareness and education of patients receiving bisphosphonates. ( Bauer, JS; Beck, N; Eitner, S; Kiefer, J; Stockmann, P; Wichmann, M, 2012)
"A rise in gastrointestinal (GI) adverse events (AEs) and a decline in bone mineral density (BMD) was observed in patients previously tolerant to brand alendronate shortly after generic versions were introduced in July 2005 to the Canadian market."1.36Adverse events, bone mineral density and discontinuation associated with generic alendronate among postmenopausal women previously tolerant of brand alendronate: a retrospective cohort study. ( Adachi, JD; Airia, P; Grima, DT; Ioannidis, G; Papaioannou, A, 2010)
" Although these agents are generally well tolerated, serious gastrointestinal adverse events, including hospitalization for gastrointestinal bleed, may arise."1.35Comparative gastrointestinal safety of weekly oral bisphosphonates. ( Brookhart, MA; Cadarette, SM; Katz, JN; Levin, R; Solomon, DH; Stedman, MR; Stürmer, T, 2009)
"Treatment with omeprazole or melatonin prevented this damage as well as the changes in biochemical parameters, and melatonin appeared to be more efficient than omeprazole in protecting the mucosa."1.33Protective effect of melatonin and omeprazole against alendronat-induced gastric damage. ( Arbak, S; Dülger, GA; Ersoy, Y; Goren, FO; Sener, G; Ulusoy, NB, 2005)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (14.63)18.2507
2000's24 (58.54)29.6817
2010's11 (26.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amiri, AH1
Tarrahi, MJ1
Panarelli, NC1
Invernizzi, M1
Cisari, C1
Carda, S1
Fadda, V1
Maratea, D1
Trippoli, S1
Messori, A1
Piscitelli, P1
Auriemma, R1
Neglia, C1
Migliore, A1
Beecham, E1
Candy, B1
Howard, R1
McCulloch, R1
Laddie, J1
Rees, H1
Vickerstaff, V1
Bluebond-Langner, M1
Jones, L1
Modi, A1
Siris, ES1
Steve Fan, CP1
Sajjan, S1
Cadarette, SM1
Katz, JN1
Brookhart, MA1
Stürmer, T1
Stedman, MR1
Levin, R1
Solomon, DH1
Blumentals, WA1
Harris, ST1
Cole, RE1
Huang, L1
Silverman, SL2
Adachi, JD3
Faraawi, RY1
O'Mahony, MF1
Nayar, A1
Massaad, R1
Evans, JK1
Yacik, C1
Grima, DT1
Papaioannou, A1
Airia, P1
Ioannidis, G1
Ralston, SH1
Kou, TD1
Wick-Urban, B1
Steinbuch, M1
Masud, T1
Bauer, JS1
Beck, N1
Kiefer, J1
Stockmann, P1
Wichmann, M1
Eitner, S1
Landfeldt, E1
Lang, A1
Robbins, S1
Ström, O1
Baker, DE1
Tremaine, WJ1
Khosla, S1
Greenspan, S1
Field-Munves, E1
Tonino, R1
Smith, M1
Petruschke, R1
Wang, L1
Yates, J2
de Papp, AE1
Palmisano, J1
Rizzoli, R2
Greenspan, SL2
Bone, G1
Schnitzer, TJ1
Watts, NB1
Adami, S3
Foldes, AJ2
Roux, C2
Levine, MA2
Uebelhart, B1
Santora, AC2
Kaur, A2
Peverly, CA1
Orloff, JJ2
Watts, N1
Freedholm, D2
Daifotis, A1
Biswas, PN1
Wilton, LV1
Shakir, SA1
Brixen, KT1
Mosekilde, L1
Aki, S1
Eskiyurt, N1
Akarirmak, U1
Tüzün, F1
Eryavuz, M1
Alper, S1
Arpacioğlu, O1
Atalay, F1
Kavuncu, V1
Kokino, S1
Kuru, O1
Nas, K1
Ozerbil, O1
Savaş, G1
Sendur, OF1
Soy, D1
Akyüz, G1
Eisman, JA1
Roman-Ivorra, J1
Lipschitz, S1
Verbruggen, N1
Gaines, KA1
Melton, ME1
Cryer, B1
Miller, P1
Petruschke, RA1
Chen, E1
Geba, GP1
Papp, AE1
Sener, G1
Goren, FO1
Ulusoy, NB1
Ersoy, Y1
Arbak, S1
Dülger, GA1
Epstein, S1
Delmas, PD1
Emkey, R3
Wilson, KM1
Hiltbrunner, V1
Schimmer, RC1
Boyd, IW1
McEwen, J1
Calcino, LJ1
Twiss, IM1
van den Berk, AH1
de Kam, ML1
Bosch, JJ1
Cohen, AF1
Vermeij, P1
Burggraaf, J1
Penning-van Beest, FJ1
Goettsch, WG1
Erkens, JA1
Herings, RM1
Halkin, H1
Dushenat, M1
Silverman, B1
Shalev, V1
Loebstein, R1
Lomnicky, Y1
Friedman, N1
Strampel, W1
Civitelli, R1
Kishimoto, H1
Kelly, R1
Taggart, H1
Kirby, M1
Mackay, F1
Mann, RD1
Young, JH1
Lombardi, A1
Bauer, DC1
Black, D1
Ensrud, K1
Thompson, D1
Hochberg, M1
Nevitt, M1
Musliner, T1
Schnitzer, T1
Bone, HG1
Crepaldi, G1
McClung, M1
Kiel, D1
Felsenberg, D1
Recker, RR1
Tonino, RP1
Pinchera, A1
Thompson, DE1
Sewell, K1
Schein, JR1
Miller, PD1
Olszynski, WP1
Kendler, DL1
Licata, AA1
Li, Z1
Gomez-Panzani, E1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A 5-year, Double-blind, Randomized, Placebo-controlled Extension Study to Examine the Long-term Safety and Efficacy of Oral Alendronate in Postmenopausal Women Who Previously Received Alendronate in Conjunction With the Fracture Intervention Trial[NCT00398931]Phase 31,099 participants (Actual)Interventional1998-02-28Completed
A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Once-Weekly Alendronate in HIV-Infected Subjects With Decreased Bone Mineral Density Receiving Calcium and Vitamin D[NCT00061256]Phase 280 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for alendronate and Cholera Infantum

ArticleYear
Drug-induced injury in the gastrointestinal tract.
    Seminars in diagnostic pathology, 2014, Volume: 31, Issue:2

    Topics: Alendronate; Angiotensin II Type 1 Receptor Blockers; Anti-Inflammatory Agents; Antineoplastic Agent

2014
The potential impact of new effervescent alendronate formulation on compliance and persistence in osteoporosis treatment.
    Aging clinical and experimental research, 2015, Volume: 27, Issue:2

    Topics: Alendronate; Bone Density Conservation Agents; Chemistry, Pharmaceutical; Esophagus; Gastrointestina

2015
Gastrointestinal and renal side effects of bisphosphonates: differentiating between no proof of difference and proof of no difference.
    Journal of endocrinological investigation, 2015, Volume: 38, Issue:2

    Topics: Alendronate; Bone Density Conservation Agents; Diphosphonates; Etidronic Acid; Female; Gastrointesti

2015
Alendronate: new formulations of an old and effective drug to improve adherence avoiding upper gastrointestinal side effects.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:24

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Chemistry, Pharmaceutical; Female; Fractures

2014
Pharmacological interventions for pain in children and adolescents with life-limiting conditions.
    The Cochrane database of systematic reviews, 2015, Mar-13, Issue:3

    Topics: Adolescent; Alendronate; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, Preschool

2015
Alendronate and risedronate: what you need to know about their upper gastrointestinal tract toxicity.
    Reviews in gastroenterological disorders, 2002, Volume: 2, Issue:1

    Topics: Alendronate; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Digestive System; Dr

2002
The clinical tolerability profile of alendronate.
    International journal of clinical practice. Supplement, 1999, Volume: 101

    Topics: Alendronate; Clinical Trials, Phase III as Topic; Double-Blind Method; Female; Gastrointestinal Dise

1999
Oral ibandronate in the management of postmenopausal osteoporosis: review of upper gastrointestinal safety.
    Maturitas, 2006, Apr-20, Volume: 54, Issue:1

    Topics: Administration, Oral; Alendronate; Bone Density Conservation Agents; Diphosphonates; Drug Administra

2006
Safety considerations with bisphosphonates for the treatment of osteoporosis.
    Drug safety, 2007, Volume: 30, Issue:9

    Topics: Acute-Phase Reaction; Administration, Oral; Alendronate; Bone Density Conservation Agents; Diphospho

2007
[Efficacy and tolerability of once-weekly administration of 35 mg alendronate and 17.5 mg risedronate].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Nov-28, Volume: 65 Suppl 9

    Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Clinical Trials as Top

2007
Osteoporosis therapies for rheumatoid arthritis patients: minimizing gastrointestinal side effects.
    Seminars in arthritis and rheumatism, 2001, Volume: 30, Issue:4

    Topics: Alendronate; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Estrogen Replacement Th

2001

Trials

11 trials available for alendronate and Cholera Infantum

ArticleYear
Comparison of gastrointestinal symptoms at daily 10 mg versus weekly 70 mg Alendronate prescription in 195 osteoporotic cases.
    Indian journal of medical sciences, 2011, Volume: 65, Issue:11

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Female; Gastrointestinal Diseases; Humans; Male

2011
Upper gastrointestinal tolerability of alendronate sodium monohydrate 10 mg once daily in postmenopausal women: a 12-week, randomized, double-blind, placebo-controlled, exploratory study.
    Clinical therapeutics, 2009, Volume: 31, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Double-Blind Method;

2009
Tolerability of once-weekly alendronate in patients with osteoporosis: a randomized, double-blind, placebo-controlled study.
    Mayo Clinic proceedings, 2002, Volume: 77, Issue:10

    Topics: Alendronate; Analysis of Variance; Bone Density; Bone Resorption; Double-Blind Method; Female; Gastr

2002
Two-year results of once-weekly administration of alendronate 70 mg for the treatment of postmenopausal osteoporosis.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2002, Volume: 17, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Alkaline Phosphatase; Bone Density; Bone Resorption; Co

2002
Upper gastrointestinal and overall tolerability of alendronate once weekly in patients with osteoporosis: results of a randomized, double-blind, placebo-controlled study.
    Current medical research and opinion, 2004, Volume: 20, Issue:5

    Topics: Administration, Oral; Alendronate; Analysis of Variance; Double-Blind Method; Female; Gastrointestin

2004
Upper gastrointestinal tolerability of once weekly alendronate 70 mg with concomitant non-steroidal anti-inflammatory drug use.
    Alimentary pharmacology & therapeutics, 2005, Mar-01, Volume: 21, Issue:5

    Topics: Aged; Alendronate; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Therapy, Combi

2005
A comparison of the gastrointestinal effects of the nitrogen-containing bisphosphonates pamidronate, alendronate, and olpadronate in humans.
    Journal of clinical pharmacology, 2006, Volume: 46, Issue:4

    Topics: Adult; Alendronate; Bone Density Conservation Agents; Cross-Over Studies; Diphosphonates; Female; Ga

2006
Treatment of Paget's disease of bone with alendronate.
    Bone, 1999, Volume: 24, Issue:5 Suppl

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Alkaline Phosphatase; Bone Resorption; Etidronic Acid;

1999
Upper gastrointestinal tract safety profile of alendronate: the fracture intervention trial.
    Archives of internal medicine, 2000, Feb-28, Volume: 160, Issue:4

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density; Digestive System; Double-Blind Method; Duodenal

2000
Therapeutic equivalence of alendronate 70 mg once-weekly and alendronate 10 mg daily in the treatment of osteoporosis. Alendronate Once-Weekly Study Group.
    Aging (Milan, Italy), 2000, Volume: 12, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alendronate; Bone Density; Dose-Response Relat

2000
Tolerability of risedronate in postmenopausal women intolerant of alendronate.
    Aging (Milan, Italy), 2001, Volume: 13, Issue:5

    Topics: Alendronate; Calcium Channel Blockers; Double-Blind Method; Etidronic Acid; Female; Gastrointestinal

2001

Other Studies

19 other studies available for alendronate and Cholera Infantum

ArticleYear
Gastrointestinal Events Among Patients Initiating Osteoporosis Therapy: A Retrospective Administrative Claims Database Analysis.
    Clinical therapeutics, 2015, Jun-01, Volume: 37, Issue:6

    Topics: Administrative Claims, Healthcare; Aged; Alendronate; Databases, Factual; Diphosphonates; Female; Ga

2015
Comparative gastrointestinal safety of weekly oral bisphosphonates.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2009, Volume: 20, Issue:10

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Diphos

2009
Risk of severe gastrointestinal events in women treated with monthly ibandronate or weekly alendronate and risedronate.
    The Annals of pharmacotherapy, 2009, Volume: 43, Issue:4

    Topics: Aged; Alendronate; Cohort Studies; Diphosphonates; Drug Administration Schedule; Etidronic Acid; Fem

2009
Adverse events, bone mineral density and discontinuation associated with generic alendronate among postmenopausal women previously tolerant of brand alendronate: a retrospective cohort study.
    BMC musculoskeletal disorders, 2010, Apr-14, Volume: 11

    Topics: Aged; Aged, 80 and over; Alendronate; Bone and Bones; Bone Density; Bone Density Conservation Agents

2010
Risk of upper gastrointestinal tract events in risedronate users switched to alendronate.
    Calcified tissue international, 2010, Volume: 87, Issue:4

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Cohort Studies; Databases, F

2010
Awareness and education of patients receiving bisphosphonates.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2012, Volume: 40, Issue:3

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alendronate; Arthralgia; Bisphosphonate-Associated Os

2012
Gastrointestinal tolerability and patterns of switching in patients treated for primary osteoporosis: the Swedish Adherence Register Analysis (SARA).
    Calcified tissue international, 2011, Volume: 89, Issue:3

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Drug Substitution; Drug-Rela

2011
Bisphosphonates and the upper gastrointestinal tract: skeletal gain without visceral pain?
    Mayo Clinic proceedings, 2002, Volume: 77, Issue:10

    Topics: Alendronate; Etidronic Acid; Female; Gastrointestinal Diseases; Humans; Osteoporosis, Postmenopausal

2002
Pharmacovigilance study of alendronate in England.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2003, Volume: 14, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Angioedema; Cohort Studies; Erythema Multiforme; Family

2003
[Alendronate once a week].
    Ugeskrift for laeger, 2003, Jun-30, Volume: 165, Issue:27

    Topics: Alendronate; Bone Density; Female; Fractures, Spontaneous; Gastrointestinal Diseases; Humans; Male;

2003
Gastrointestinal side effect profile due to the use of alendronate in the treatment of osteoporosis.
    Yonsei medical journal, 2003, Dec-30, Volume: 44, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Female; Gastrointestinal Diseases; Humans; Middle Aged;

2003
Protective effect of melatonin and omeprazole against alendronat-induced gastric damage.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:8

    Topics: Administration, Oral; Alendronate; Animals; Anti-Ulcer Agents; Antioxidants; Fasting; Female; Gastri

2005
A study of codispensing with sodium alendronate in Australia.
    British journal of clinical pharmacology, 2006, Volume: 61, Issue:4

    Topics: Alendronate; Australia; Bone Density Conservation Agents; Calcitriol; Cohort Studies; Databases, Fac

2006
Determinants of persistence with bisphosphonates: a study in women with postmenopausal osteoporosis.
    Clinical therapeutics, 2006, Volume: 28, Issue:2

    Topics: Age Factors; Aged; Alendronate; Bone Density Conservation Agents; Databases, Factual; Drug Administr

2006
Brand versus generic alendronate: gastrointestinal effects measured by resource utilization.
    The Annals of pharmacotherapy, 2007, Volume: 41, Issue:1

    Topics: Aged; Alendronate; Chemistry, Pharmaceutical; Cohort Studies; Drugs, Generic; Female; Gastrointestin

2007
Incidence of gastrointestinal side effects due to alendronate is high in clinical practice.
    BMJ (Clinical research ed.), 1997, Nov-08, Volume: 315, Issue:7117

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Gastrointestinal Diseases; Humans; Middle Aged

1997
Tolerability of alendronate. Comparison group taking placebo should have been included.
    BMJ (Clinical research ed.), 1998, May-02, Volume: 316, Issue:7141

    Topics: Aged; Alendronate; Female; Fractures, Bone; Gastrointestinal Diseases; Humans

1998
Tolerability of alendronate. Figures given in letter were prevalences, not incidences.
    BMJ (Clinical research ed.), 1998, May-02, Volume: 316, Issue:7141

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alendronate; Gastrointestinal Diseases; Humans; Middle A

1998
Tolerability of alendronate. Manufacturer's comment.
    BMJ (Clinical research ed.), 1998, May-02, Volume: 316, Issue:7141

    Topics: Aged; Alendronate; Female; Gastrointestinal Diseases; Humans

1998