alendronate has been researched along with Carcinoma 256, Walker in 3 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
Carcinoma 256, Walker: A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The findings suggest that there is no pharmacodynamic advantage for continuous infusion of alendronate." | 1.31 | Pharmacokinetic and pharmacodynamic evaluation of intermittent versus continuous alendronate administration in rats. ( Golomb, G; Hoffman, A; Stepensky, D, 2002) |
| "To validate our hypothesis that a bisphosphonate (BP) having a nitrogen-containing heterocyclic ring on the side chain, and with no hydroxyl on the geminal carbon would possess increased activity, and better oral bioavailability due to enhanced solubility of its calcium complexes/salts and weaker Ca chelating properties." | 1.30 | Synthesis and preclinical pharmacology of 2-(2-aminopyrimidinio) ethylidene-1,1-bisphosphonic acid betaine (ISA-13-1)-a novel bisphosphonate. ( Alferiev, IS; Breuer, E; Cohen, H; Ezra, A; Golomb, G; Hägele, G; Hoffman, A; Mönkkönen, J; Ornoy, A; Patlas, N; Pinto, T; Sagi, H; Seibel, MJ; Solomon, V; Stepensky, D, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, H | 1 |
| Alferiev, IS | 1 |
| Mönkkönen, J | 1 |
| Seibel, MJ | 1 |
| Pinto, T | 1 |
| Ezra, A | 1 |
| Solomon, V | 1 |
| Stepensky, D | 2 |
| Sagi, H | 1 |
| Ornoy, A | 1 |
| Patlas, N | 1 |
| Hägele, G | 1 |
| Hoffman, A | 2 |
| Breuer, E | 1 |
| Golomb, G | 2 |
| Kozak, S | 1 |
| Rizzoli, R | 1 |
| Trechsel, U | 1 |
| Fleisch, H | 1 |
3 other studies available for alendronate and Carcinoma 256, Walker
| Article | Year |
|---|---|
Synthesis and preclinical pharmacology of 2-(2-aminopyrimidinio) ethylidene-1,1-bisphosphonic acid betaine (ISA-13-1)-a novel bisphosphonate.
Topics: Administration, Oral; Alendronate; Animals; Antineoplastic Agents; Betaine; Bone Diseases; Bone Neop | 1999 |
Pharmacokinetic and pharmacodynamic evaluation of intermittent versus continuous alendronate administration in rats.
Topics: Alendronate; Animals; Bone Neoplasms; Bone Resorption; Calcium; Carcinoma 256, Walker; Drug Administ | 2002 |
Effect of a single injection of two new bisphosphonates on the hypercalcemia and hypercalciuria induced by Walker carcinosarcoma 256/B in thyroparathyroidectomized rats.
Topics: Alendronate; Animals; Bone Resorption; Calcium; Carcinoma 256, Walker; Diphosphonates; Hypercalcemia | 1987 |