Page last updated: 2024-10-22

alendronate and Bone Spur

alendronate has been researched along with Bone Spur in 5 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Research Excerpts

ExcerptRelevanceReference
"To employ elemental Strontium as a tracer of bone turnover, in the presence (or absence) of the bisphosphonate drug Alendronate, in order to spatially map osteophytogenesis and other bone turnover in rats developing post-traumatic secondary osteoarthritis (PTOA)."7.78Potential mechanism of alendronate inhibition of osteophyte formation in the rat model of post-traumatic osteoarthritis: evaluation of elemental strontium as a molecular tracer of bone formation. ( Doschak, MR; Maksymowych, WP; Panahifar, A, 2012)
"Mechanical loading and alendronate (ALN) can be used as noninvasive physical therapy methods for osteoarthritis (OA)."4.31Axial Compressive Loading Attenuates Early Osteoarthritis by Reducing Subchondral Bone Remodeling. ( Cai, H; Fu, L; Li, G; Liu, C; Liu, Q; Liu, Y; Pan, Y; Wu, J; Yang, Q; Yu, Y; Zhong, J, 2023)
"To employ elemental Strontium as a tracer of bone turnover, in the presence (or absence) of the bisphosphonate drug Alendronate, in order to spatially map osteophytogenesis and other bone turnover in rats developing post-traumatic secondary osteoarthritis (PTOA)."3.78Potential mechanism of alendronate inhibition of osteophyte formation in the rat model of post-traumatic osteoarthritis: evaluation of elemental strontium as a molecular tracer of bone formation. ( Doschak, MR; Maksymowych, WP; Panahifar, A, 2012)
"Loading induced cartilage pathology, osteophyte formation, and SCB changes; however, lower initial SCB mass and stiffness in B6 mice did not attenuate load-induced OA severity compared to FVB mice."1.46Role of subchondral bone properties and changes in development of load-induced osteoarthritis in mice. ( Adebayo, OO; Goldring, MB; Goldring, SR; Ko, FC; van der Meulen, MCH; Wan, PT; Wright, TM, 2017)
"Alendronate treatment reduced bony osteophyte development."1.36In vivo microfocal computed tomography and micro-magnetic resonance imaging evaluation of antiresorptive and antiinflammatory drugs as preventive treatments of osteoarthritis in the rat. ( Doschak, MR; Jones, MD; Li, G; Maksymowych, WP; Tran, CW; Zernicke, RF, 2010)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Wu, J1
Pan, Y1
Yu, Y1
Yang, Q1
Liu, Q1
Liu, Y1
Zhong, J1
Fu, L1
Cai, H1
Liu, C1
Li, G2
Adebayo, OO1
Ko, FC1
Wan, PT1
Goldring, SR1
Goldring, MB1
Wright, TM1
van der Meulen, MCH1
Jones, MD1
Tran, CW1
Maksymowych, WP2
Zernicke, RF1
Doschak, MR2
Panahifar, A1
Neogi, T1
Nevitt, MC1
Ensrud, KE1
Bauer, D1
Felson, DT1

Trials

1 trial available for alendronate and Bone Spur

ArticleYear
The effect of alendronate on progression of spinal osteophytes and disc-space narrowing.
    Annals of the rheumatic diseases, 2008, Volume: 67, Issue:10

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Disease Progression; Female; Humans; Interverte

2008

Other Studies

4 other studies available for alendronate and Bone Spur

ArticleYear
Axial Compressive Loading Attenuates Early Osteoarthritis by Reducing Subchondral Bone Remodeling.
    The American journal of sports medicine, 2023, Volume: 51, Issue:7

    Topics: Alendronate; Animals; Bone Remodeling; Cartilage, Articular; Disease Models, Animal; Inflammation; M

2023
Role of subchondral bone properties and changes in development of load-induced osteoarthritis in mice.
    Osteoarthritis and cartilage, 2017, Volume: 25, Issue:12

    Topics: Alendronate; Animals; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Cancellous Bo

2017
In vivo microfocal computed tomography and micro-magnetic resonance imaging evaluation of antiresorptive and antiinflammatory drugs as preventive treatments of osteoarthritis in the rat.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:9

    Topics: Alendronate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Density Conservation Agents; Dis

2010
Potential mechanism of alendronate inhibition of osteophyte formation in the rat model of post-traumatic osteoarthritis: evaluation of elemental strontium as a molecular tracer of bone formation.
    Osteoarthritis and cartilage, 2012, Volume: 20, Issue:7

    Topics: Alendronate; Animals; Arthritis, Experimental; Bone Density Conservation Agents; Drug Evaluation, Pr

2012