Page last updated: 2024-10-22

alendronate and Back Pain

alendronate has been researched along with Back Pain in 17 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Back Pain: Acute or chronic pain located in the posterior regions of the THORAX; LUMBOSACRAL REGION; or the adjacent regions.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to investigate the effect of alendronate on metacarpal and lumbar bone mineral density (BMD), bone resorption, and chronic back pain in postmenopausal women with osteoporosis."9.11Effects of alendronate on metacarpal and lumbar bone mineral density, bone resorption, and chronic back pain in postmenopausal women with osteoporosis. ( Iwamoto, J; Sato, Y; Takeda, T; Uzawa, M, 2004)
"Exercise may enhance the effect of alendronate on bone mineral density (BMD) and reduce chronic back pain in elderly women with osteoporosis."9.11Effect of whole-body vibration exercise on lumbar bone mineral density, bone turnover, and chronic back pain in post-menopausal osteoporotic women treated with alendronate. ( Iwamoto, J; Sato, Y; Takeda, T; Uzawa, M, 2005)
"To compare the effects on back pain of teriparatide versus alendronate, we analyzed the reporting of back pain in a head to head comparator trial and a followup study."9.11Longterm reduction of back pain risk in women with osteoporosis treated with teriparatide compared with alendronate. ( Body, JJ; Chen, P; Krege, JH; Miller, PD; Rohe, ME; Shergy, WJ, 2005)
"The purpose of the present study was to compare the effects of treatment with etidronate and alendronate on bone resorption, back pain, and activities of daily living (ADL) in elderly women with vertebral fractures."9.10Comparative effects of treatment with etidronate and alendronate on bone resorption, back pain, and activities of daily living in elderly women with vertebral fractures. ( Ichimura, S; Iwamoto, J; Takeda, T; Uzawa, M, 2003)
"To determine the effect of alendronate therapy on days affected by back pain in postmenopausal women with existing vertebral fractures."9.09Effect of alendronate on limited-activity days and bed-disability days caused by back pain in postmenopausal women with existing vertebral fractures. Fracture Intervention Trial Research Group. ( Black, DM; Cummings, SR; Ensrud, K; Nevitt, MC; Rubin, SR; Thompson, DE; Yates, AJ, 2000)
"Efficacy and safety of a new combination package containing 4 or 12 self-explanatory one-week blisters, each with one tablet of 70 mg alendronate (CAS 260055-05-8) and 7 capsules of 1 microg alfacalcidol (CAS 41294-56-8) (Tevabone) on muscle power, muscle function, balance and back pain was investigated in an open, multi-centered, uncontrolled, prospective study on a cohort of elderly patients with a high risk of falls and fractures."7.77Risk reduction of falls and fractures, reduction of back pain and safety in elderly high risk patients receiving combined therapy with alfacalcidol and alendronate: a prospective study. ( Ringe, JD; Schacht, E, 2011)
"The purpose of this study was to investigate the effect of alendronate on metacarpal and lumbar bone mineral density (BMD), bone resorption, and chronic back pain in postmenopausal women with osteoporosis."5.11Effects of alendronate on metacarpal and lumbar bone mineral density, bone resorption, and chronic back pain in postmenopausal women with osteoporosis. ( Iwamoto, J; Sato, Y; Takeda, T; Uzawa, M, 2004)
"Exercise may enhance the effect of alendronate on bone mineral density (BMD) and reduce chronic back pain in elderly women with osteoporosis."5.11Effect of whole-body vibration exercise on lumbar bone mineral density, bone turnover, and chronic back pain in post-menopausal osteoporotic women treated with alendronate. ( Iwamoto, J; Sato, Y; Takeda, T; Uzawa, M, 2005)
"To compare the effects on back pain of teriparatide versus alendronate, we analyzed the reporting of back pain in a head to head comparator trial and a followup study."5.11Longterm reduction of back pain risk in women with osteoporosis treated with teriparatide compared with alendronate. ( Body, JJ; Chen, P; Krege, JH; Miller, PD; Rohe, ME; Shergy, WJ, 2005)
"The purpose of this open-labeled prospective study was to compare the treatment effects of cyclical etidronate and alendronate on the lumbar bone mineral density (BMD), bone resorption, and back pain in elderly women with osteoporosis."5.11Comparison of effect of treatment with etidronate and alendronate on lumbar bone mineral density in elderly women with osteoporosis. ( Iwamoto, J; Sato, Y; Takeda, T; Uzawa, M, 2005)
"The purpose of the present study was to examine the early response of lumbar bone mineral density (BMD), bone resorption, and back pain to alendronate after treatment with cyclical etidronate in postmenopausal women with osteoporosis."5.10Early response to alendronate after treatment with etidronate in postmenopausal women with osteoporosis. ( Ichimura, S; Iwamoto, J; Takeda, T; Uzawa, M, 2003)
"The purpose of the present study was to compare the effects of treatment with etidronate and alendronate on bone resorption, back pain, and activities of daily living (ADL) in elderly women with vertebral fractures."5.10Comparative effects of treatment with etidronate and alendronate on bone resorption, back pain, and activities of daily living in elderly women with vertebral fractures. ( Ichimura, S; Iwamoto, J; Takeda, T; Uzawa, M, 2003)
"To determine the effect of alendronate therapy on days affected by back pain in postmenopausal women with existing vertebral fractures."5.09Effect of alendronate on limited-activity days and bed-disability days caused by back pain in postmenopausal women with existing vertebral fractures. Fracture Intervention Trial Research Group. ( Black, DM; Cummings, SR; Ensrud, K; Nevitt, MC; Rubin, SR; Thompson, DE; Yates, AJ, 2000)
"Efficacy and safety of a new combination package containing 4 or 12 self-explanatory one-week blisters, each with one tablet of 70 mg alendronate (CAS 260055-05-8) and 7 capsules of 1 microg alfacalcidol (CAS 41294-56-8) (Tevabone) on muscle power, muscle function, balance and back pain was investigated in an open, multi-centered, uncontrolled, prospective study on a cohort of elderly patients with a high risk of falls and fractures."3.77Risk reduction of falls and fractures, reduction of back pain and safety in elderly high risk patients receiving combined therapy with alfacalcidol and alendronate: a prospective study. ( Ringe, JD; Schacht, E, 2011)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (70.59)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ofluoglu, O1
Ofluoglu, D1
Iwamoto, J6
Makita, K1
Sato, Y4
Takeda, T6
Matsumoto, H1
Schacht, E2
Ringe, JD2
Dukas, L1
Mazor, Z1
Dytfeld, J1
Horst-Sikorska, W1
Yoshioka, T1
Okimoto, N1
Okamoto, K1
Sakai, A1
Ichimura, S2
Uzawa, M5
Witzig, M1
Bützberger, S1
Caravatti, M1
Furrer, J1
Schulthess, G1
Sarikaya, S1
Ozdolap, S1
Açikgöz, G1
Erdem, CZ1
Nakamura, T1
Ghose, R1
Miller, PD1
Shergy, WJ1
Body, JJ1
Chen, P1
Rohe, ME1
Krege, JH1
Nevitt, MC1
Thompson, DE1
Black, DM1
Rubin, SR1
Ensrud, K1
Yates, AJ1
Cummings, SR1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Minodronate in the Treatment of Postmenopausal Osteoporosis With Low Back Pain: a Single-centre and Randomized Controlled Trial[NCT05645289]Phase 472 participants (Anticipated)Interventional2023-01-01Not yet recruiting
A 5-year, Double-blind, Randomized, Placebo-controlled Extension Study to Examine the Long-term Safety and Efficacy of Oral Alendronate in Postmenopausal Women Who Previously Received Alendronate in Conjunction With the Fracture Intervention Trial[NCT00398931]Phase 31,099 participants (Actual)Interventional1998-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for alendronate and Back Pain

ArticleYear
[Fracture Intervention Trial I and II(alendronate)].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 2

    Topics: Activities of Daily Living; Alendronate; Back Pain; Controlled Clinical Trials as Topic; Humans; Ost

2004

Trials

9 trials available for alendronate and Back Pain

ArticleYear
Alendronate is more effective than elcatonin in improving pain and quality of life in postmenopausal women with osteoporosis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2011, Volume: 22, Issue:10

    Topics: Aged; Aged, 80 and over; Alendronate; Alkaline Phosphatase; Back Pain; Calcitonin; Collagen Type I;

2011
A comparative study of the effects of daily minodronate and weekly alendronate on upper gastrointestinal symptoms, bone resorption, and back pain in postmenopausal osteoporosis patients.
    Journal of bone and mineral metabolism, 2013, Volume: 31, Issue:2

    Topics: Aged; Alendronate; Back Pain; Biomarkers; Bone Density; Bone Density Conservation Agents; Bone Remod

2013
Early response to alendronate after treatment with etidronate in postmenopausal women with osteoporosis.
    The Keio journal of medicine, 2003, Volume: 52, Issue:2

    Topics: Aged; Aged, 80 and over; Alendronate; Back Pain; Bone Density; Calcium; Collagen; Collagen Type I; E

2003
Comparative effects of treatment with etidronate and alendronate on bone resorption, back pain, and activities of daily living in elderly women with vertebral fractures.
    The Keio journal of medicine, 2003, Volume: 52, Issue:4

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alendronate; Back Pain; Bone Resorption; Disabi

2003
Effects of alendronate on metacarpal and lumbar bone mineral density, bone resorption, and chronic back pain in postmenopausal women with osteoporosis.
    Clinical rheumatology, 2004, Volume: 23, Issue:5

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Alendronate; Back Pain; Biomarkers; Bone Density; B

2004
Effect of whole-body vibration exercise on lumbar bone mineral density, bone turnover, and chronic back pain in post-menopausal osteoporotic women treated with alendronate.
    Aging clinical and experimental research, 2005, Volume: 17, Issue:2

    Topics: Accidental Falls; Aged; Aged, 80 and over; Alendronate; Alkaline Phosphatase; Back Pain; Bone Densit

2005
Longterm reduction of back pain risk in women with osteoporosis treated with teriparatide compared with alendronate.
    The Journal of rheumatology, 2005, Volume: 32, Issue:8

    Topics: Aged; Alendronate; Back Pain; Female; Follow-Up Studies; Humans; Incidence; Middle Aged; Osteoporosi

2005
Comparison of effect of treatment with etidronate and alendronate on lumbar bone mineral density in elderly women with osteoporosis.
    Yonsei medical journal, 2005, Dec-31, Volume: 46, Issue:6

    Topics: Aged; Aged, 80 and over; Alendronate; Back Pain; Biomarkers; Bone Density; Bone Density Conservation

2005
Effect of alendronate on limited-activity days and bed-disability days caused by back pain in postmenopausal women with existing vertebral fractures. Fracture Intervention Trial Research Group.
    Archives of internal medicine, 2000, Jan-10, Volume: 160, Issue:1

    Topics: Activities of Daily Living; Aged; Alendronate; Back Pain; Bed Rest; Bone Density; Double-Blind Metho

2000

Other Studies

7 other studies available for alendronate and Back Pain

ArticleYear
A case report: pregnancy-induced severe osteoporosis with eight vertebral fractures.
    Rheumatology international, 2008, Volume: 29, Issue:2

    Topics: Adult; Alendronate; Back Pain; Bone Density; Bone Density Conservation Agents; Female; Fractures, Sp

2008
Risk reduction of falls and fractures, reduction of back pain and safety in elderly high risk patients receiving combined therapy with alfacalcidol and alendronate: a prospective study.
    Arzneimittel-Forschung, 2011, Volume: 61, Issue:1

    Topics: Accidental Falls; Aged; Aged, 80 and over; Alendronate; Back Pain; Bone Density Conservation Agents;

2011
Potency of a combined alfacalcidol-alendronate therapy to reduce the risk of falls and fractures in elderly patients with glucocorticoid-induced osteoporosis.
    Arzneimittel-Forschung, 2011, Volume: 61, Issue:2

    Topics: Absorptiometry, Photon; Accidental Falls; Aged; Alendronate; Back Pain; Bone Density; Bone Density C

2011
Pregnancy associated osteoporosis--a case report.
    Ginekologia polska, 2012, Volume: 83, Issue:5

    Topics: Adult; Alendronate; Back Pain; Bone Density; Bone Density Conservation Agents; Calcium, Dietary; Fem

2012
[Backache and palmar eczema (SAPHO syndrome)].
    Deutsche medizinische Wochenschrift (1946), 2003, Aug-22, Volume: 128, Issue:34-35

    Topics: Acquired Hyperostosis Syndrome; Alendronate; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Dia

2003
Pregnancy-associated osteoporosis with vertebral fractures and scoliosis.
    Joint bone spine, 2004, Volume: 71, Issue:1

    Topics: Absorptiometry, Photon; Adult; Alendronate; Back Pain; Bone Density; Calcium Carbonate; Exercise The

2004
Osteomalacia: recovery of bone density.
    The New Zealand medical journal, 2004, Jun-18, Volume: 117, Issue:1196

    Topics: 25-Hydroxyvitamin D 2; Absorptiometry, Photon; Aged; Alendronate; Alkaline Phosphatase; Back Pain; B

2004