Page last updated: 2024-10-22

alendronate and Atherosclerosis

alendronate has been researched along with Atherosclerosis in 6 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.

Research Excerpts

ExcerptRelevanceReference
"40 rats were randomly divided into 4 groups: control, untreated atherosclerosis group, atherosclerotic rats treated with carvedilol (10mg/kg/d) and atherosclerotic rats treated with alendronate sodium (10mg/kg/d)."4.02Matrix metalloproteinase 9 a potential major player connecting atherosclerosis and osteoporosis in high fat diet fed rats. ( Abdelgwad, M; Estaphan, S; Kamar, S; Mostafa, S; Rashed, L; Sabry, M, 2021)
"Osteoporosis and atherosclerosis are the two most common diseases in postmenopausal women."2.79Change in arterial stiffness associated with monthly bisphosphonate treatment in women with postmenopausal osteoporosis. ( Igase, M; Kohara, K; Miki, T; Ochi, M; Ohara, M; Okada, Y; Tabara, Y; Takita, R, 2014)
" However, an inverse dose-response relationship was seen, with an increased risk in those with low adherence (≤0."1.38Acute myocardial infarction and atherosclerosis of the coronary arteries in patients treated with drugs against osteoporosis: calcium in the vessels and not the bones? ( Vestergaard, P, 2012)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Sabry, M1
Mostafa, S1
Rashed, L1
Abdelgwad, M1
Kamar, S1
Estaphan, S1
Igase, M1
Kohara, K1
Tabara, Y1
Ohara, M1
Takita, R1
Ochi, M1
Okada, Y1
Miki, T1
Mohamed, MT1
Abuelezz, SA1
Atalla, SS1
El Aziz, LFA1
Gorge, SS1
Strandberg, TE1
Vestergaard, P1
Yamada, S1
Inaba, M1
Nishizawa, Y1

Reviews

1 review available for alendronate and Atherosclerosis

ArticleYear
[Influence on atherosclerosis of improvement of bone mineral density after medication for osteoporosis].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Nov-28, Volume: 65 Suppl 9

    Topics: Alendronate; Apolipoprotein A-I; Arthritis, Rheumatoid; Atherosclerosis; Bone and Bones; Bone Densit

2007

Trials

1 trial available for alendronate and Atherosclerosis

ArticleYear
Change in arterial stiffness associated with monthly bisphosphonate treatment in women with postmenopausal osteoporosis.
    Menopause (New York, N.Y.), 2014, Volume: 21, Issue:9

    Topics: Administration, Oral; Aged; Alendronate; Ankle Brachial Index; Atherosclerosis; Bone Density Conserv

2014

Other Studies

4 other studies available for alendronate and Atherosclerosis

ArticleYear
Matrix metalloproteinase 9 a potential major player connecting atherosclerosis and osteoporosis in high fat diet fed rats.
    PloS one, 2021, Volume: 16, Issue:2

    Topics: Alendronate; Alkaline Phosphatase; Animals; Atherosclerosis; Biomarkers; Bone Density; Bone Remodeli

2021
The anti-osteoporotic and anti-atherogenic effects of alendronate and simvastatin in ovariectomized rats fed high fat diet: A comparative study of combination therapy versus monotherapy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 89

    Topics: Alendronate; Alkaline Phosphatase; Animals; Atherosclerosis; Body Weight; Bone and Bones; Bone Densi

2017
Alendronate, osteoporosis, and atherosclerosis.
    Archives of internal medicine, 2008, Nov-24, Volume: 168, Issue:21

    Topics: Alendronate; Atherosclerosis; Atrial Fibrillation; Bone Density Conservation Agents; Humans; Osteopo

2008
Acute myocardial infarction and atherosclerosis of the coronary arteries in patients treated with drugs against osteoporosis: calcium in the vessels and not the bones?
    Calcified tissue international, 2012, Volume: 90, Issue:1

    Topics: Aged; Alendronate; Atherosclerosis; Bone Density Conservation Agents; Calcium; Cohort Studies; Dipho

2012